BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0041.0053.p (325 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2065 [CR] COG0604 NADPH Rso Ralstonia solanacearum 476 e-134 AGc1508 [CR] COG0604 NADPH Atu Agrobacterium tumefaciens strain ... 374 e-103 BMEI0302 [CR] COG0604 NADPH Bme Brucella melitensis 372 e-103 YPO1653 [CR] COG0604 NADPH Ype Yersinia pestis 365 e-101 SMc00034 [CR] COG0604 NADPH Sme Sinorhizobium meliloti 355 6e-98 >RSc2065 [CR] COG0604 NADPH Rso Ralstonia solanacearum Length = 334 Score = 476 bits (1226), Expect = e-134, Method: Compositional matrix adjust. Identities = 242/332 (72%), Positives = 271/332 (81%), Gaps = 10/332 (3%) Query: 1 MRAIEIKEFGGPEVLQACERPVPELKAGEVLIKVHAAGVNRPDVFQRTGNYPVPPGASDL 60 MRAIEI ++GGP+VL+ ERP+PE KAGEVLI+V AAGVNRPDVFQRTGNYPVPPGASD+ Sbjct: 1 MRAIEITQYGGPDVLKPAERPMPEPKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDI 60 Query: 61 PGLEVAGEIVAGDLGDS----GFKLGDLVCALVQGGGYAEFCAAPLAQCLPVPKGLSALE 116 PGLEVAGEIV GDL + G + GD VCALVQGGGYAEFC APL Q LPVP GLS +E Sbjct: 61 PGLEVAGEIVGGDLAHADNRYGLRAGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDIE 120 Query: 117 AAALPENYFTVWSNVFDRGQLS-----GEETLLVQGGSSGIGVTAIQIARALGHRVFATA 171 AAALPENYFTVWSNVFDRGQL ETLLVQGGSSGIG TAIQ+A ALG+RVFATA Sbjct: 121 AAALPENYFTVWSNVFDRGQLGQGAHGKGETLLVQGGSSGIGTTAIQMASALGYRVFATA 180 Query: 172 GSAEKCRACEELGAERAINYKTEDFEAVVKELTGGRGVDVILDMVGGDYLPREIKALADD 231 GS EKC AC LGA RAI Y+TEDF VVK TG RGVDV+LDMVGG Y+ REI ADD Sbjct: 181 GSDEKCAACVALGAARAIRYRTEDFAEVVKAETG-RGVDVVLDMVGGSYVAREIACTADD 239 Query: 232 GRLVFIAQLGGAKGQLDMGQVMRRRLTITGSTLRPRPVAFKAAIAAKLREHVWPLIEAGK 291 GR+V IA LGGAK ++ +G+++RRR+T+TGSTLRPRPVAFKAAIAA L + VWPL+ +G+ Sbjct: 240 GRIVLIALLGGAKAEVPLGEILRRRITLTGSTLRPRPVAFKAAIAAHLHDTVWPLLASGR 299 Query: 292 IRPVIHHRFPLEQAAQAHAMMEGSTHIGKIML 323 IRPVIH P E AAQAHA+ME S HIGKIML Sbjct: 300 IRPVIHEVMPAEHAAQAHALMESSAHIGKIML 331 >AGc1508 [CR] COG0604 NADPH Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 348 Score = 374 bits (960), Expect = e-103, Method: Compositional matrix adjust. Identities = 186/326 (57%), Positives = 237/326 (72%), Gaps = 1/326 (0%) Query: 1 MRAIEIKEFGGPEVLQACERPVPELKAGEVLIKVHAAGVNRPDVFQRTGNYPVPPGASDL 60 MR I++ GGPEV+Q+ + P+P+ GE+L+KV AAGVNRPDV QR G YP P GAS + Sbjct: 22 MRFIDLPSHGGPEVMQSSKAPLPKPARGEILVKVEAAGVNRPDVAQRQGIYPPPKGASPI 81 Query: 61 PGLEVAGEIVAGDLGDSGFKLGDLVCALVQGGGYAEFCAAPLAQCLPVPKGLSALEAAAL 120 GLE+AGE+VA G FKLGD VCAL GGGYAE+CA P Q LP PKG A++AAAL Sbjct: 82 LGLEIAGEVVALGEGVDEFKLGDKVCALANGGGYAEYCAVPAGQALPFPKGYDAVKAAAL 141 Query: 121 PENYFTVWSNVFDRGQLSGEETLLVQGGSSGIGVTAIQIARALGHRVFATAGSAEKCRAC 180 PE +FTVW+N+F L+ ET+L+ GG+SGIG TAIQ+A+A G V+ATAGSAEKC AC Sbjct: 142 PETFFTVWANLFQMAGLTEGETVLIHGGTSGIGTTAIQLAKAFGAEVYATAGSAEKCEAC 201 Query: 181 EELGAERAINYKTEDFEAVVKELTGGRGVDVILDMVGGDYLPREIKALADDGRLVFIAQL 240 +LG +RAINY+ EDF +VK TGG+GVDV+LDM+G Y + + ALA DG L IA L Sbjct: 202 VKLGTKRAINYREEDFAEIVKSETGGKGVDVVLDMIGAAYFEKNLAALAKDGCLSIIAFL 261 Query: 241 GGAKGQ-LDMGQVMRRRLTITGSTLRPRPVAFKAAIAAKLREHVWPLIEAGKIRPVIHHR 299 GGA + +D+ +M +RLT+TGST+RPR K AI +L E VWPLIE+GK+ PVI+ Sbjct: 262 GGATAEKVDLRPIMVKRLTVTGSTMRPRTADEKRAIRDELVEQVWPLIESGKVAPVINRV 321 Query: 300 FPLEQAAQAHAMMEGSTHIGKIMLEL 325 F LE+ AH +ME S HIGKI++++ Sbjct: 322 FTLEEVVDAHRLMESSNHIGKIVMKV 347 >BMEI0302 [CR] COG0604 NADPH Bme Brucella melitensis Length = 336 Score = 372 bits (955), Expect = e-103, Method: Compositional matrix adjust. Identities = 191/325 (58%), Positives = 232/325 (71%) Query: 1 MRAIEIKEFGGPEVLQACERPVPELKAGEVLIKVHAAGVNRPDVFQRTGNYPVPPGASDL 60 M AIEI E GG +L+ +R VPE K GE+L++V AAGVNRPDV QR G Y PPGASD+ Sbjct: 11 MTAIEITEPGGAYMLRPAQRAVPEPKEGEILVRVRAAGVNRPDVLQRQGQYAPPPGASDI 70 Query: 61 PGLEVAGEIVAGDLGDSGFKLGDLVCALVQGGGYAEFCAAPLAQCLPVPKGLSALEAAAL 120 PGLE+AG+IVA G F+ GD V AL+ GGGYAE+ + LP+P G +EAAA+ Sbjct: 71 PGLEIAGDIVALGHGVKRFRKGDQVVALLAGGGYAEYAVVHESNALPLPSGFGYIEAAAI 130 Query: 121 PENYFTVWSNVFDRGQLSGEETLLVQGGSSGIGVTAIQIARALGHRVFATAGSAEKCRAC 180 PE +FTVW NVF+RG L E LV GGSSGIG TAIQ+A+A G V TAGS EKC AC Sbjct: 131 PETFFTVWHNVFERGGLKEGEVFLVHGGSSGIGTTAIQLAKAFGATVITTAGSKEKCDAC 190 Query: 181 EELGAERAINYKTEDFEAVVKELTGGRGVDVILDMVGGDYLPREIKALADDGRLVFIAQL 240 +LGA+RAINY EDF AVVKE+TGG+GVDVILDMVGGDY+ R KA A+DGR++ IA L Sbjct: 191 VKLGADRAINYHEEDFVAVVKEMTGGKGVDVILDMVGGDYVERNYKAAAEDGRIMQIAFL 250 Query: 241 GGAKGQLDMGQVMRRRLTITGSTLRPRPVAFKAAIAAKLREHVWPLIEAGKIRPVIHHRF 300 GAK + +M +RLT TGSTLRPRPVAFKA IA +L VWPL+ ++ PV+ F Sbjct: 251 NGAKATANFAILMTKRLTHTGSTLRPRPVAFKAGIARELEAKVWPLLAQRRVAPVMDMIF 310 Query: 301 PLEQAAQAHAMMEGSTHIGKIMLEL 325 L+ A +AH ME HIGKI+L++ Sbjct: 311 SLKDAWRAHERMEEGRHIGKIVLDI 335 >YPO1653 [CR] COG0604 NADPH Ype Yersinia pestis Length = 336 Score = 365 bits (938), Expect = e-101, Method: Compositional matrix adjust. Identities = 183/324 (56%), Positives = 229/324 (70%), Gaps = 1/324 (0%) Query: 1 MRAIEIKEFGGPEVLQACERPVPELKAGEVLIKVHAAGVNRPDVFQRTGNYPVPPGASDL 60 M AIEI +FGGPEVL +RP P AGE+L+KV AAGVNRPDV QR G Y PPGASD+ Sbjct: 11 MVAIEITQFGGPEVLVPAKRPTPMPAAGEILVKVSAAGVNRPDVMQRRGQYAPPPGASDI 70 Query: 61 PGLEVAGEIVAGDLGDSGFKLGDLVCALVQGGGYAEFCAAPLAQCLPVPKGLSALEAAAL 120 PGLEVAGE+VA + FK+GD VC L+ GGGYA++C LP+P+GLSA+EAAAL Sbjct: 71 PGLEVAGEVVATAADVTRFKIGDNVCGLIAGGGYAQYCVIHETNALPIPQGLSAIEAAAL 130 Query: 121 PENYFTVWSNVFDRGQLSGEETLLVQGGSSGIGVTAIQIARALG-HRVFATAGSAEKCRA 179 PE +FTVW+N+F RG + ET+L+ GGSSGIG TAI +++A G V T GS EK +A Sbjct: 131 PETFFTVWTNLFQRGHFTAGETVLIHGGSSGIGTTAILLSKAFGAATVIVTVGSEEKRQA 190 Query: 180 CEELGAERAINYKTEDFEAVVKELTGGRGVDVILDMVGGDYLPREIKALADDGRLVFIAQ 239 C LGA+ AINY T+DF A K T G+G DVI+D++ GDY+ R A A +GR+V I Sbjct: 191 CLNLGADIAINYHTQDFVAETKRATAGKGADVIVDLIAGDYVARNYDAAAMNGRIVQIGT 250 Query: 240 LGGAKGQLDMGQVMRRRLTITGSTLRPRPVAFKAAIAAKLREHVWPLIEAGKIRPVIHHR 299 G L++ ++ +RLT TGSTLR R VA KA IA +L +HVWPL+ GK++P I Sbjct: 251 QNGHAKDLNLMLMLIKRLTHTGSTLRSRTVAEKALIANELEQHVWPLLSEGKMKPQIFST 310 Query: 300 FPLEQAAQAHAMMEGSTHIGKIML 323 FPLE AA+AH +ME STHIGKI+L Sbjct: 311 FPLEAAAKAHELMESSTHIGKIVL 334 >SMc00034 [CR] COG0604 NADPH Sme Sinorhizobium meliloti Length = 327 Score = 355 bits (912), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 183/326 (56%), Positives = 225/326 (69%), Gaps = 1/326 (0%) Query: 1 MRAIEIKEFGGPEVLQACERPVPELKAGEVLIKVHAAGVNRPDVFQRTGNYPVPPGASDL 60 M +++ GGPE + P+PE++ G++LI+V A G+NRPDV QR G+YP+P GAS + Sbjct: 1 MTYVDLPGPGGPENMVLARGPLPEVRPGDILIRVEAFGINRPDVLQRKGDYPLPAGASPI 60 Query: 61 PGLEVAGEIVAGDLGDSGFKLGDLVCALVQGGGYAEFCAAPLAQCLPVPKGLSALEAAAL 120 GLE AGE+VA G +GF GD VCAL GG YAE+CA P Q L PKG A +AAAL Sbjct: 61 LGLEAAGEVVALGEGATGFSTGDKVCALANGGAYAEYCAVPATQALRWPKGYDAAKAAAL 120 Query: 121 PENYFTVWSNVFDRGQLSGEETLLVQGGSSGIGVTAIQIARALGHRVFATAGSAEKCRAC 180 PE +FTVW+NVFD +L ET LV GGSSGIG TAIQ+ARA G VFATAG+A KC AC Sbjct: 121 PETFFTVWANVFDMARLKSGETFLVHGGSSGIGTTAIQLARAFGAEVFATAGNAAKCEAC 180 Query: 181 EELGAERAINYKTEDFEAVVKELTGGRGVDVILDMVGGDYLPREIKALADDGRLVFIAQL 240 E LGA+RAINY+ EDF+AVV + TGGRGVDVILDMVGG Y R I +LA DGRL IA L Sbjct: 181 EALGAKRAINYREEDFKAVVLQETGGRGVDVILDMVGGRYFDRNIGSLAKDGRLSIIAFL 240 Query: 241 GGAK-GQLDMGQVMRRRLTITGSTLRPRPVAFKAAIAAKLREHVWPLIEAGKIRPVIHHR 299 GGA+ ++ ++ +RL + GS LRPR A K AI L E VWPL+E G + PVI Sbjct: 241 GGARVDGANIAPILMKRLQVMGSLLRPRTAAEKQAIRDGLAEKVWPLLEGGDVAPVIQAV 300 Query: 300 FPLEQAAQAHAMMEGSTHIGKIMLEL 325 P + A AH +ME HIGKI++ + Sbjct: 301 LPFAEIAGAHRLMEEGDHIGKIVMRI 326