BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0039.0233.p         (185 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

lin0572 [E] COG0107 Imidazoleglycerol-phosphate synthase Lin Lis...    74   1e-13
aq_181 [E] COG0107 Imidazoleglycerol-phosphate synthase Aae Aqui...    73   4e-13
L0071 [E] COG0107 Imidazoleglycerol-phosphate synthase Lla Lacto...    72   8e-13
CAC0941 [E] COG0107 Imidazoleglycerol-phosphate synthase Cac Clo...    71   1e-12
SA2465 [E] COG0107 Imidazoleglycerol-phosphate synthase Sau Stap...    65   1e-10

>lin0572 [E] COG0107 Imidazoleglycerol-phosphate synthase Lin Listeria
           innocua
          Length = 251

 Score = 74.3 bits (181), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 50/169 (29%), Positives = 85/169 (50%), Gaps = 7/169 (4%)

Query: 6   PLIYGGGIASAEDGVKVIQAGADRISIDALLHDAPQVLIELGYQLGVQALIAAVPMRMHN 65
           PL  GGGI S  D  +++QAGAD+IS+++     P+++ E   + G Q ++ A+  + + 
Sbjct: 76  PLTVGGGINSVNDMKELLQAGADKISLNSAAIKRPELIQEGANKFGNQCIVVAIDAKWNG 135

Query: 66  QMPCWHDYRH--RRDLPLAALE--KVLGRGLASELLVIDCEHEGRAASFDTHLLDALPD- 120
               WH +    R D  L A+E  K   +  A E+L+   + +G    +D  L  A+ + 
Sbjct: 136 SN--WHVFTRGGRDDTGLDAIEWAKKATQLGAGEILLTSMDGDGTKNGYDIPLTKAISEA 193

Query: 121 WNMPLLAFGGISEASQMEELLARPRVAAVGVGNFLSYRELAIQQYKKVL 169
            ++P++A GG   AS M E+  +    A    +   Y EL+I+  K  L
Sbjct: 194 VSVPVIASGGCGNASHMVEVFEQTNATAALAASIFHYGELSIKNVKTTL 242


>aq_181 [E] COG0107 Imidazoleglycerol-phosphate synthase Aae Aquifex
           aeolicus
          Length = 253

 Score = 72.8 bits (177), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 50/170 (29%), Positives = 85/170 (50%), Gaps = 9/170 (5%)

Query: 6   PLIYGGGIASAEDGVKVIQAGADRISIDALLHDAPQVLIELGYQLGVQALIAAVPMRMHN 65
           P   GGGI S ED  ++++AGAD+ISI+      P ++ E   + G Q ++ A+  +   
Sbjct: 76  PFTVGGGIRSLEDMRRLLEAGADKISINTAAVKNPNLIYEGAKRFGSQCIVVAIDAKRKG 135

Query: 66  QMPCWHDYRH--RRDLPLAALE---KVLGRGLASELLVIDCEHEGRAASFDTHLLDALPD 120
               W  Y H  R    L A+E   KV   G A E+L+   + +G    +D  L  A+ +
Sbjct: 136 N--SWEVYIHGGRTPTGLDAVEWAKKVESLG-AGEILLTSMDRDGTKDGYDIELNRAISE 192

Query: 121 -WNMPLLAFGGISEASQMEELLARPRVAAVGVGNFLSYRELAIQQYKKVL 169
             N+P++A GG  +     E+ ++ +V A    +   +RE++I + K+ L
Sbjct: 193 AVNIPVIASGGAGKKEHFYEVFSKTKVEAALAASVFHFREISIPELKEYL 242


>L0071 [E] COG0107 Imidazoleglycerol-phosphate synthase Lla Lactococcus
           lactis
          Length = 259

 Score = 71.6 bits (174), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 46/172 (26%), Positives = 82/172 (47%), Gaps = 5/172 (2%)

Query: 3   LGTPLIYGGGIASAEDGVKVIQAGADRISIDALLHDAPQVLIELGYQLGVQALIAAVPMR 62
           L  PL +GGGI S +D  +++  GAD++S+++   + P+++ +   +LGVQ ++ A+  +
Sbjct: 73  LSIPLTFGGGIRSIDDFRRILARGADKVSVNSAAIENPELIRQAANELGVQCVVVAIDAK 132

Query: 63  MHNQMPCWHDY----RHRRDLPLAALEKVLGRGLASELLVIDCEHEGRAASFDTHLL-DA 117
                  +  Y    R    L L    K   R  A E+L+   + +G    +D  +L D 
Sbjct: 133 KRADHRGYDVYIKGGRENAGLDLVDWAKKCERLGAGEILLTSMDKDGTKTGYDLEMLNDV 192

Query: 118 LPDWNMPLLAFGGISEASQMEELLARPRVAAVGVGNFLSYRELAIQQYKKVL 169
               N+P++A GG  + S + E+    R  A  V +   Y E  + + K  L
Sbjct: 193 CTAVNIPVVASGGCGKISDIVEVFQNTRSDAALVASLFHYGEATVDEVKDEL 244


>CAC0941 [E] COG0107 Imidazoleglycerol-phosphate synthase Cac Clostridium
           acetobutylicum
          Length = 253

 Score = 71.2 bits (173), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 49/181 (27%), Positives = 88/181 (48%), Gaps = 11/181 (6%)

Query: 6   PLIYGGGIASAEDGVKVIQAGADRISIDALLHDAPQVLIELGYQLGVQALIAAVPMRMHN 65
           PL  GGGI   +D   +++AGAD+ISI++     P+++ E   + G Q ++ AV  R + 
Sbjct: 76  PLTVGGGIRDVDDFKNILRAGADKISINSAAIRNPELINEAAKKFGSQCVVVAVDARRNI 135

Query: 66  QMPCWHDYRH--RRDLPLAALEKV-----LGRGLASELLVIDCEHEGRAASFDTHLLDAL 118
           +   ++ + +  R D  L A+E V     LG G   E+L+   + +G    +D  L  A+
Sbjct: 136 ETGGFNVFINGGRVDTSLDAIEWVKKCESLGAG---EILLTSMDADGTKNGYDVELTGAV 192

Query: 119 PD-WNMPLLAFGGISEASQMEELLARPRVAAVGVGNFLSYRELAIQQYKKVLASPALRPA 177
            D   +P++A GG       +E+  +    A  V +   Y+E  + + K  L   +++  
Sbjct: 193 CDAVRIPVIASGGCGRLEDFDEIFKKTSADAALVASLFHYKEYTVGEVKNYLRENSIQVR 252

Query: 178 L 178
           L
Sbjct: 253 L 253


>SA2465 [E] COG0107 Imidazoleglycerol-phosphate synthase Sau Staphylococcus
           aureus N315
          Length = 252

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 48/170 (28%), Positives = 80/170 (47%), Gaps = 7/170 (4%)

Query: 6   PLIYGGGIASAEDGVKVIQAGADRISIDALLHDAPQVLIELGYQLGVQALIAAV-----P 60
           PL  GGGI S +D  +++  GAD++S+++     PQ++ +   + G Q +  A+     P
Sbjct: 76  PLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDP 135

Query: 61  MRMHNQMPCWHDYRHRRDLPLAALEKVLGRGLASELLVIDCEHEGRAASFDT-HLLDALP 119
            R      C H  +   ++ +    + + +  A ELLV    H+G    FD  HL     
Sbjct: 136 ER-KAHYCCTHGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLAKIKS 194

Query: 120 DWNMPLLAFGGISEASQMEELLARPRVAAVGVGNFLSYRELAIQQYKKVL 169
             N+P++A GG   A    EL  +  V+A    + L  RE  +Q  K+V+
Sbjct: 195 LVNIPIIASGGGGNAQHFVELFNQTDVSAGLAASILHDRETTVQSIKEVI 244