BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0161.p (271 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ydbS [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Eco Esc... 260 3e-69 PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 216 4e-56 PA3591 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 201 2e-51 AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu A... 201 2e-51 BMEI1945 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme... 199 4e-51 >ydbS [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Eco Escherichia coli K12 Length = 255 Score = 260 bits (664), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 139/246 (56%), Positives = 175/246 (71%), Gaps = 1/246 (0%) Query: 9 DLLAARHGEHVLHLTLNRPALRNALRNQSLREIVAALARAEEDDSVRVVVISGNEKAFAA 68 +L+ +R + VL LTLNRPA RNAL N L ++V L A D S+ V VI+GN + FAA Sbjct: 3 ELIVSRQ-QRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAA 61 Query: 69 GADLNEMIHKDAIATQLDVRAQYWRAIARFPKPILAAVNGYALGAGCELLMHADIAIAAR 128 GADLNEM KD AT D R Q W + F KP++AAVNGYALGAGCEL + D+ +A Sbjct: 62 GADLNEMAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGE 121 Query: 129 GAKIGQPEINVGTIPGAGGTQRLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDD 188 A+ G PEI +G +PGAGGTQRLIR+VGK LA KMVLSGE I+A QA QAGLV++V D Sbjct: 122 NARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSD 181 Query: 189 ATLERTLALAHSIAQKSPLAVRLAKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGI 248 TLE L LA +A+ SPLA++ AK+A+ QS E+ L+AGL ER+ F+L+AA+ DR EGI Sbjct: 182 LTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGI 241 Query: 249 AAFQEK 254 +AF +K Sbjct: 242 SAFLQK 247 >PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 261 Score = 216 bits (550), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 112/233 (48%), Positives = 154/233 (66%) Query: 22 LTLNRPALRNALRNQSLREIVAALARAEEDDSVRVVVISGNEKAFAAGADLNEMIHKDAI 81 L LNRP RNAL ++ + + + D ++RV+V++G+ + FAAGADL ++ AI Sbjct: 21 LRLNRPQARNALNDEVRQRLASHFQTLGADPAIRVIVLTGDSRCFAAGADLRDLSTSTAI 80 Query: 82 ATQLDVRAQYWRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEINVGT 141 +YW AIAR PKP++AAVNG+ALG GCEL MH D+ +A A+ QPEI VG Sbjct: 81 GLYGRHGERYWEAIARCPKPVIAAVNGFALGGGCELAMHCDLIVAGESAQFAQPEIKVGV 140 Query: 142 IPGAGGTQRLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALAHSI 201 +PGAGGTQRL+R VGK A++M+ +G + A QAL GLV+EVV D++TL R L LA I Sbjct: 141 MPGAGGTQRLVRAVGKFQALRMLFTGCLVKAPQALAMGLVSEVVADESTLARALELAMEI 200 Query: 202 AQKSPLAVRLAKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEK 254 A+ PLA+ KE +L +L L++ L ERK+F L+ S D++EG+ AF EK Sbjct: 201 ARLPPLALAQIKEVVLAGADLPLDSALALERKAFQLLFDSQDQKEGMHAFLEK 253 >PA3591 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 265 Score = 201 bits (510), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 119/251 (47%), Positives = 159/251 (63%), Gaps = 2/251 (0%) Query: 5 VAYEDLLAARHGEHVLHLTLNRPALRNALRNQSLREIVAA-LARAEEDDSVRVVVISGNE 63 V E +L R + V L LNRPA+ NAL N LRE +A + R +E RV+V++GN Sbjct: 8 VRPELVLLERPEQGVALLRLNRPAVLNAL-NMRLREALAEHVRRLDECADTRVIVLTGNG 66 Query: 64 KAFAAGADLNEMIHKDAIATQLDVRAQYWRAIARFPKPILAAVNGYALGAGCELLMHADI 123 AFAAGADLNE+ A+ Q ++W+A+A KP++AAV G+ALG GCEL MH D+ Sbjct: 67 TAFAAGADLNELAEASALEIQQRGVERHWQALAACRKPLIAAVEGHALGGGCELAMHCDL 126 Query: 124 AIAARGAKIGQPEINVGTIPGAGGTQRLIRTVGKPLAMKMVLSGEFISADQALQAGLVAE 183 +A A+ QPEI VG +PGAGGTQRL+R VGK A++M+ +G + A +AL GLV+E Sbjct: 127 IVAGASARFAQPEIRVGVMPGAGGTQRLVRAVGKFQALRMLFTGCTVRAPEALAIGLVSE 186 Query: 184 VVDDDATLERTLALAHSIAQKSPLAVRLAKEAMLQSFELGLEAGLLFERKSFSLMAASAD 243 V D L+R L LA IA PLA+ KE +L +L L+ L ERK+F L+ S D Sbjct: 187 VAADGQALDRALELARQIAGLPPLALAQIKEVVLAGADLPLDQALALERKAFQLLFDSHD 246 Query: 244 RQEGIAAFQEK 254 ++EG+ AF EK Sbjct: 247 QKEGMRAFLEK 257 >AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 256 Score = 201 bits (510), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 115/236 (48%), Positives = 154/236 (65%), Gaps = 8/236 (3%) Query: 23 TLNRPALRNALRNQSLREIVAALARAEEDDSVRVVVISGNEKAFAAGADLNEMIHKDAI- 81 TLNRP NAL ++ E+ + EE RV++I+G+ KAFAAGAD+NE++ +DAI Sbjct: 17 TLNRPEKLNALDTKTRMELAEVIEGIEE--VARVLIITGSGKAFAAGADINELLQRDAIK 74 Query: 82 ---ATQLDVRAQYWRAIARFPKPILAAVNGYALGAGCELLMHADIAIAARGAKIGQPEIN 138 AT+L + I P++AAVNGY LG GCEL M DI IA+ AK GQPEIN Sbjct: 75 AFEATKLGT--DLFSRIEELEIPVIAAVNGYTLGGGCELAMACDIRIASEKAKFGQPEIN 132 Query: 139 VGTIPGAGGTQRLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEVVDDDATLERTLALA 198 + IPGAGGTQRL R VG +A K+VL+GE I A AL+ GLV EVV+ + +ER +A Sbjct: 133 LAIIPGAGGTQRLPRLVGLGMAKKLVLTGEIIDAQTALRIGLVEEVVEHERLMERAKEVA 192 Query: 199 HSIAQKSPLAVRLAKEAMLQSFELGLEAGLLFERKSFSLMAASADRQEGIAAFQEK 254 I +KSPLAV++AK+A+ S + L+ GL +E F+L+ +S D +EG+ AF EK Sbjct: 193 AKIIEKSPLAVKVAKKALNASINMPLKEGLRYEASLFALLFSSEDAKEGMRAFLEK 248 >BMEI1945 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 293 Score = 199 bits (507), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 114/250 (45%), Positives = 155/250 (62%), Gaps = 1/250 (0%) Query: 5 VAYEDLLAARHGEHVLHLTLNRPALRNALRNQSLREIVAALARAEEDDSVRVVVISGNEK 64 +AYE ++ + V + LNRP NAL L E+ ALA + D V VV++G+EK Sbjct: 37 MAYETIIVETR-DSVGLIRLNRPQALNALNRAVLEELTDALAAFDADGKVGAVVLTGSEK 95 Query: 65 AFAAGADLNEMIHKDAIATQLDVRAQYWRAIARFPKPILAAVNGYALGAGCELLMHADIA 124 AFAAGAD+ EM + + L W+ + R KPI+AAV+GYALG GCEL M D Sbjct: 96 AFAAGADIKEMQLINFVDAYLQDMFADWQKVDRIRKPIIAAVSGYALGGGCELAMMCDFI 155 Query: 125 IAARGAKIGQPEINVGTIPGAGGTQRLIRTVGKPLAMKMVLSGEFISADQALQAGLVAEV 184 IA AK GQPEI +G IPG GG+QRL R VGK AM M L+G + A +A + GLV+ V Sbjct: 156 IAGSNAKFGQPEITLGAIPGMGGSQRLTRYVGKSKAMDMCLTGRMMDAAEAERCGLVSRV 215 Query: 185 VDDDATLERTLALAHSIAQKSPLAVRLAKEAMLQSFELGLEAGLLFERKSFSLMAASADR 244 V +A LE L A IA S ++V +AKEA+ +++E L+ GL FER+ F + A+ D+ Sbjct: 216 VAPEALLEEALKAAERIASFSRVSVYMAKEAVNRAYETTLDEGLRFERRLFHSLFATEDQ 275 Query: 245 QEGIAAFQEK 254 +EG++AF +K Sbjct: 276 KEGMSAFVDK 285