BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0152.p (305 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb21636 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH red... 333 4e-91 RSp0608 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH redu... 290 2e-78 paaE [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reducta... 230 3e-60 MT3658_2 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH red... 227 2e-59 Rv3554_2 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH red... 227 3e-59 >SMb21636 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Sme Sinorhizobium meliloti Length = 358 Score = 333 bits (853), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 163/358 (45%), Positives = 225/358 (62%), Gaps = 55/358 (15%) Query: 1 MSKFYPLTISDVKQETRDTIVVSFAVPAELQDTFSYQQGQHLTLRSEINGEDLRRSYSIC 60 M++FYPL +++V+++TRD +VV+ E + F + QGQ+LT R GE+LRRSYSIC Sbjct: 1 MARFYPLQVTEVRRDTRDAVVVTLEPREEDRAAFDFTQGQYLTFRRLFGGEELRRSYSIC 60 Query: 61 SAVQERQLRVAIKRAPGGLFSNWANESFVPGQRIDVMPPMGHFNVPLEAGNRKHYLAFAA 120 + + E L+V IKR G FS+WANE PG ++ MPPMG F P+E KHYL FA Sbjct: 61 AGLDEGALKVGIKRVDDGCFSSWANEELEPGDTLEAMPPMGAFFTPIEPEAAKHYLGFAG 120 Query: 121 GSGITPMMSIIKTTLLSEPHSHFTLVYANRASSSVIFKEELTDLKDTYLERFNVVYVMSR 180 GSGITP++S++KT L EP S FTLVYANR SS++F+EEL DLK+ YL R +V++V+ Sbjct: 121 GSGITPVLSLVKTVLAREPRSAFTLVYANRHFSSIMFREELDDLKNLYLGRLSVLHVLES 180 Query: 181 EQQDVELFNGRIDRAKCDAFFASWIDLKDVDAAFLCGPEDMVQAVAASLQAHGLPKTQIK 240 E Q+++LF+GR+DR KC A F SWID++ D AF+CGPE M+ VAA+L+AHGL +IK Sbjct: 181 EAQEIDLFSGRLDREKCTALFRSWIDVRSADTAFICGPEPMMLGVAAALRAHGLGDDRIK 240 Query: 241 TELFAASTPPRAHA---------ARAVC-------------------------------- 259 ELFAAS P RA +RA C Sbjct: 241 FELFAASQPGRARRKVESAAGADSRARCEATVTLDGATRSFTFPKEGLSLLEAALENRMD 300 Query: 260 --------------GKVVEGKVDMDANYALEDYEIARGFVLSCQSFPVSDKLLLDFDQ 303 KV+EG+V+M++N ALEDYE+ +G+VL+CQS+P+SD++++ +DQ Sbjct: 301 APFACKAGVCSSCRAKVLEGEVEMESNNALEDYEVEQGYVLTCQSYPLSDRIVVSYDQ 358 >RSp0608 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Rso Ralstonia solanacearum Length = 363 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 156/359 (43%), Positives = 219/359 (61%), Gaps = 58/359 (16%) Query: 3 KFYPLTISDVKQETRDTIVVSFAVPAELQDTFSYQQGQHLTLRSEINGE---DLRRSYSI 59 +F+PL +++V+ ET DTI + F VP +L++ + + QGQ LTLR +LRRSYSI Sbjct: 4 QFHPLRVAEVRGETADTISLRFDVPDDLREAYRFTQGQFLTLRVPAGAAGQGELRRSYSI 63 Query: 60 CSAVQER----QLRVAIKRAPGGLFSNWANESFVPGQRIDVMPPMGHFNVPLEAGNRKHY 115 C AVQ+ +LRVA+KR G+FSN ++ GQ +DV+PP G F VPL A + +HY Sbjct: 64 CCAVQDYDAHGELRVAVKRVDAGVFSNHLHDRIRVGQTLDVLPPDGRFYVPLAAESARHY 123 Query: 116 LAFAAGSGITPMMSIIKTTLLSEPHSHFTLVYANRASSSVIFKEELTDLKDTYLERFNVV 175 +AFAAGSGITP++S+IKTTL +EPHS FTLVY NR S+IF E L DLKD YL+RF + Sbjct: 124 VAFAAGSGITPVLSLIKTTLAAEPHSRFTLVYGNRTVDSIIFAEALEDLKDRYLDRFALY 183 Query: 176 YVMSREQQDVELFNGRIDRAKCDAFFASWIDLKDVDAAFLCGPEDMVQAVAASLQAHGLP 235 +V+SR+ Q++ LFNGR+D K AF + I D+DAAF+CGP M+ AV A+L A G+P Sbjct: 184 HVLSRQPQEIALFNGRLDGDKARAFLDTLIPPDDIDAAFICGPSTMIDAVEAALLARGVP 243 Query: 236 KTQIKTELFA-----ASTPPRAHAARA--------------------------------- 257 + ++ E F AS PR AA A Sbjct: 244 RERVHAERFGVPVGDASARPRKPAAVAGDVALTVVLDGKSHHVPMAGDGKVLDSALAAGL 303 Query: 258 ---------VC----GKVVEGKVDMDANYALEDYEIARGFVLSCQSFPVSDKLLLDFDQ 303 VC KV+EG+V+M+ N+ LED+EI +GFVL+CQ+ P++ ++++ +D+ Sbjct: 304 DLPYACKGGVCCTCRAKVLEGRVEMEKNFTLEDWEIRQGFVLTCQARPLTQRVVVSYDE 362 >paaE [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Eco Escherichia coli K12 Length = 356 Score = 230 bits (587), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 111/249 (44%), Positives = 160/249 (64%), Gaps = 2/249 (0%) Query: 1 MSKFYPLTISDVKQETRDTIVVSFAVPAELQDTFSYQQGQHLTLRSEINGEDLRRSYSIC 60 M+ F+ LT++ V+ ETRD + ++FAVP LQ+ + ++ GQHLTL++ +GE+LRR YSIC Sbjct: 1 MTTFHSLTVAKVESETRDAVTITFAVPQPLQEAYRFRPGQHLTLKASFDGEELRRCYSIC 60 Query: 61 SAVQERQLRVAIKRAPGGLFSNWANESFVPGQRIDVMPPMGHFNVPLEAGNRKHYLAFAA 120 + ++ VA+K GG FS +A E G ++VM P GHF +A + YLA AA Sbjct: 61 RSYLPGEISVAVKAIEGGRFSRYAREHIRQGMTLEVMVPQGHFGYQPQAERQGRYLAIAA 120 Query: 121 GSGITPMMSIIKTTLLSEPHSHFTLVYANRASSSVIFKEELTDLKDTYLERFNVVYVMSR 180 GSGITPM++II TTL +EP S FTL+Y NR S S++F++ L DLKD Y +R ++ + S+ Sbjct: 121 GSGITPMLAIIATTLQTEPESQFTLIYGNRTSQSMMFRQALADLKDKYPQRLQLLCIFSQ 180 Query: 181 EQQDVELFNGRIDRAKCDAFFASWIDLKDVDAAFLCGPEDMVQAVAASLQAHGLPKTQIK 240 E D +L +GRID K + AS I+ + D AF+CGP M+ +L+A G+P I Sbjct: 181 ETLDSDLLHGRIDGEKLQSLGASLINFRLYDEAFICGPAAMMDDAETALKALGMPDKTIH 240 Query: 241 TELFAASTP 249 E F +TP Sbjct: 241 LERF--NTP 247 >MT3658_2 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 MtC Mycobacterium tuberculosis CDC1551 Length = 360 Score = 227 bits (579), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 122/342 (35%), Positives = 180/342 (52%), Gaps = 46/342 (13%) Query: 7 LTISDVKQETRDTIVVSFAVPAELQDTFSYQQGQHLTLRSEINGEDLRRSYSICSAVQER 66 + ++ V T D +V+FAVP L+D F ++ GQH+T+R+++ G+ +RR+YSIC+ Sbjct: 18 IPVASVDPITADATLVTFAVPEALRDAFRFEPGQHVTVRTDLGGQGIRRNYSICAPATRA 77 Query: 67 QLRVAIKRAPGGLFSNWANESFVPGQRIDVMPPMGHFNVPLEAGNRKHYLAFAAGSGITP 126 QLR+A+K PGG FS + G +++M P G F PL+ +RKHY+ AGSGITP Sbjct: 78 QLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGTPLDPLHRKHYVGLVAGSGITP 137 Query: 127 MMSIIKTTLLSEPHSHFTLVYANRASSSVIFKEELTDLKDTYLERFNVVYVMSREQQDVE 186 ++SI+ TTL E S FTL+Y NR S +F+ EL L+ Y +R +++V+S E Sbjct: 138 VLSILATTLEIETESRFTLIYGNRTKESTMFRAELDRLESRYADRLEILHVLSSEPLHTP 197 Query: 187 LFNGRIDRAKCDAFFASWIDLKDVDAAFLCGPEDMVQAVAASLQAHGLPKTQIKTELFAA 246 GRIDR K + S + VD F+CGP M AV +L HG+ +I ELF Sbjct: 198 ELRGRIDRDKLTRWLTSTLRPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYG 257 Query: 247 -STPPRAHAA-------------RAV----------------------------CG---- 260 TPP + RA+ CG Sbjct: 258 FDTPPATRPSYAGATVTFTLSGQRAIFDLVPGDSILEGALGLRSDAPYACMGGACGTCRA 317 Query: 261 KVVEGKVDMDANYALEDYEIARGFVLSCQSFPVSDKLLLDFD 302 K++EG V+MD N+AL E+ G++L+CQS P + + +D+D Sbjct: 318 KLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAVDYD 359 >Rv3554_2 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Mtu Mycobacterium tuberculosis H37Rv Length = 350 Score = 227 bits (578), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 122/342 (35%), Positives = 180/342 (52%), Gaps = 46/342 (13%) Query: 7 LTISDVKQETRDTIVVSFAVPAELQDTFSYQQGQHLTLRSEINGEDLRRSYSICSAVQER 66 + ++ V T D +V+FAVP L+D F ++ GQH+T+R+++ G+ +RR+YSIC+ Sbjct: 8 IPVASVDPITADATLVTFAVPEALRDAFRFEPGQHVTVRTDLGGQGIRRNYSICAPATRA 67 Query: 67 QLRVAIKRAPGGLFSNWANESFVPGQRIDVMPPMGHFNVPLEAGNRKHYLAFAAGSGITP 126 QLR+A+K PGG FS + G +++M P G F PL+ +RKHY+ AGSGITP Sbjct: 68 QLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGTPLDPLHRKHYVGLVAGSGITP 127 Query: 127 MMSIIKTTLLSEPHSHFTLVYANRASSSVIFKEELTDLKDTYLERFNVVYVMSREQQDVE 186 ++SI+ TTL E S FTL+Y NR S +F+ EL L+ Y +R +++V+S E Sbjct: 128 VLSILATTLEIETESRFTLIYGNRTKESTMFRAELDRLESRYADRLEILHVLSSEPLHTP 187 Query: 187 LFNGRIDRAKCDAFFASWIDLKDVDAAFLCGPEDMVQAVAASLQAHGLPKTQIKTELFAA 246 GRIDR K + S + VD F+CGP M AV +L HG+ +I ELF Sbjct: 188 ELRGRIDRDKLTRWLTSTLRPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYG 247 Query: 247 -STPPRAHAA-------------RAV----------------------------CG---- 260 TPP + RA+ CG Sbjct: 248 FDTPPATRPSYAGATVTFTLSGQRAIFDLVPGDSILEGALGLRSDAPYACMGGACGTCRA 307 Query: 261 KVVEGKVDMDANYALEDYEIARGFVLSCQSFPVSDKLLLDFD 302 K++EG V+MD N+AL E+ G++L+CQS P + + +D+D Sbjct: 308 KLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAVDYD 349