BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0106.p (216 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB1579 [E] COG0040 ATP phosphoribosyltransferase Nme Neisseria ... 309 3e-84 NMA1768 [E] COG0040 ATP phosphoribosyltransferase NmA Neisseria ... 309 3e-84 PA4449 [E] COG0040 ATP phosphoribosyltransferase Pae Pseudomonas... 247 2e-65 BS_hisG [E] COG0040 ATP phosphoribosyltransferase Bsu Bacillus s... 184 1e-46 BH3583 [E] COG0040 ATP phosphoribosyltransferase Bha Bacillus ha... 171 9e-43 >NMB1579 [E] COG0040 ATP phosphoribosyltransferase Nme Neisseria meningitidis MC58 Length = 217 Score = 309 bits (791), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 151/212 (71%), Positives = 177/212 (83%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 LT+ALSKGRIFEETLPLL AAGI +E+PE SRKLI+ TN ++R++IVRA+DVPTYV+Y Sbjct: 6 LTIALSKGRIFEETLPLLAAAGIVPTEEPEKSRKLIIGTNHENIRLVIVRATDVPTYVRY 65 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 GAADFG+AGKDVL+EHGG GLY+P+DL IAKCR+ VAV++GFDY A + G RL++ TKY Sbjct: 66 GAADFGIAGKDVLIEHGGTGLYRPLDLEIAKCRMMVAVRKGFDYEAASQPGCRLKIATKY 125 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 A HFA KGVHVD+IKLYGSMEL PLVGLSDAIVDLVSTG TL+AN L VEHI+DI Sbjct: 126 PEIAASHFAGKGVHVDIIKLYGSMELAPLVGLSDAIVDLVSTGNTLKANGLEAVEHIVDI 185 Query: 185 SSRLVVNQAALKLKRERLQPILDAFEKASKAK 216 SSRLVVN+AALK K L+PI+ AF A KAK Sbjct: 186 SSRLVVNKAALKTKYALLEPIIQAFGGAVKAK 217 >NMA1768 [E] COG0040 ATP phosphoribosyltransferase NmA Neisseria meningitidis Z2491 Length = 217 Score = 309 bits (791), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 151/212 (71%), Positives = 177/212 (83%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 LT+ALSKGRIFEETLPLL AAGI +E+PE SRKLI+ TN ++R++IVRA+DVPTYV+Y Sbjct: 6 LTIALSKGRIFEETLPLLAAAGIVPTEEPEKSRKLIIGTNHENIRLVIVRATDVPTYVRY 65 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 GAADFG+AGKDVL+EHGG GLY+P+DL IAKCR+ VAV++GFDY A + G RL++ TKY Sbjct: 66 GAADFGIAGKDVLIEHGGTGLYRPLDLEIAKCRMMVAVRKGFDYEAASQPGCRLKIATKY 125 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 A HFA KGVHVD+IKLYGSMEL PLVGLSDAIVDLVSTG TL+AN L VEHI+DI Sbjct: 126 PEIAASHFAGKGVHVDIIKLYGSMELAPLVGLSDAIVDLVSTGNTLKANGLEAVEHIVDI 185 Query: 185 SSRLVVNQAALKLKRERLQPILDAFEKASKAK 216 SSRLVVN+AALK K L+PI+ AF A KAK Sbjct: 186 SSRLVVNKAALKTKYALLEPIIQAFGGAVKAK 217 >PA4449 [E] COG0040 ATP phosphoribosyltransferase Pae Pseudomonas aeruginosa Length = 211 Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 125/212 (58%), Positives = 162/212 (76%), Gaps = 5/212 (2%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 LT+ALSKGRI ++TLPLL AAGI SE+P+ SRKLI+PT+ DVR++IVRA+DVPTYV++ Sbjct: 2 LTIALSKGRILDDTLPLLAAAGIVPSENPDKSRKLIIPTSLSDVRLLIVRATDVPTYVEH 61 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 GAAD GVAGKDVL+E+GG+GLY+P+DL IA C+L A G A RLRV TK+ Sbjct: 62 GAADLGVAGKDVLMEYGGQGLYEPLDLRIANCKLMTAGAIG-----APEPKGRLRVATKF 116 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 VN A+ ++A +G VD+IKLYGSMEL PLVGL+D I+D+V TG TLRAN L E I I Sbjct: 117 VNVAKRYYAEQGRQVDVIKLYGSMELAPLVGLADKIIDVVDTGNTLRANGLEPQELIATI 176 Query: 185 SSRLVVNQAALKLKRERLQPILDAFEKASKAK 216 SSRLVVN+A++K++ R+Q ++D A +A+ Sbjct: 177 SSRLVVNKASMKMQHGRIQSLIDTLRDAVEAR 208 >BS_hisG [E] COG0040 ATP phosphoribosyltransferase Bsu Bacillus subtilis Length = 213 Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 96/198 (48%), Positives = 135/198 (68%), Gaps = 6/198 (3%) Query: 1 MTQQLTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPT 60 M + LT+A+ KGRIFEE LL+ AG + E+ E SRKLI+ + ++R I+ + DV T Sbjct: 1 MGKLLTMAMPKGRIFEEAAGLLRQAGYRLPEEFEDSRKLIIDVPEENLRFILAKPMDVTT 60 Query: 61 YVQYGAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRV 120 YV++G AD G+AGKDV+LE + +Y+ +DLNI+KC L+VA D++ G R+ Sbjct: 61 YVEHGVADVGIAGKDVMLEEERD-VYEVLDLNISKCHLAVAGLPNTDWS-----GVAPRI 114 Query: 121 VTKYVNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEH 180 TKY N A +F +G V++IKL GS+EL PL+GL+D IVD+VSTG TL+ N LVE EH Sbjct: 115 ATKYPNVASSYFREQGEQVEIIKLNGSIELAPLIGLADRIVDIVSTGQTLKENGLVETEH 174 Query: 181 IIDISSRLVVNQAALKLK 198 I DI+SR +VN + ++K Sbjct: 175 ICDITSRFIVNPVSYRMK 192 >BH3583 [E] COG0040 ATP phosphoribosyltransferase Bha Bacillus halodurans Length = 212 Score = 171 bits (434), Expect = 9e-43, Method: Compositional matrix adjust. Identities = 90/203 (44%), Positives = 141/203 (69%), Gaps = 5/203 (2%) Query: 5 LTLALSKGRIFEETLPLLKAAGITVSEDPESSRKLILPTNDPDVRVIIVRASDVPTYVQY 64 LT+A+ KGRIF+E + LL+ AG + + E+SRKLI+ + ++R I+ + DVPTYV++ Sbjct: 4 LTVAMPKGRIFDEAVGLLRKAGYNLPAEFEASRKLIVDVPEENMRFILAKPMDVPTYVEH 63 Query: 65 GAADFGVAGKDVLLEHGGEGLYQPIDLNIAKCRLSVAVQEGFDYANAVRQGARLRVVTKY 124 G AD GVAGKDV+LE + +Y+ +DL I++C L+VA ++ + + +V +KY Sbjct: 64 GVADVGVAGKDVMLEEERD-VYEVLDLKISECYLAVAGLPNYEKKHDLNP----KVASKY 118 Query: 125 VNTAREHFAAKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANKLVEVEHIIDI 184 + A +F +G V++IKL GS+EL PL+GL+D IVD+VSTG TLR N LVE+E ++ I Sbjct: 119 PHLATRYFKEQGEQVEIIKLNGSIELAPLIGLADRIVDIVSTGRTLRENGLVELEKMMTI 178 Query: 185 SSRLVVNQAALKLKRERLQPILD 207 +SRL+VN + ++K ER+ +++ Sbjct: 179 TSRLIVNPVSYRMKDERIDEMVE 201