BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0103.p (372 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2951 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 420 e-117 NMA1771 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 273 4e-73 NMB1582 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 266 4e-71 aq_2084 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 216 6e-56 DR2461 [E] COG0079 Histidinol-phosphate/aromatic aminotransferas... 179 1e-44 >RSc2951 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Rso Ralstonia solanacearum Length = 374 Score = 420 bits (1079), Expect = e-117, Method: Compositional matrix adjust. Identities = 222/367 (60%), Positives = 273/367 (74%), Gaps = 3/367 (0%) Query: 8 PEPESIDQLIANVIRPVVRGWQSYHVPSAEGMVKLDAMENPYLLPAELREQLAQRLAALE 67 P S+D L+ ++R VR +YHVP A GMVKLDAMENPY LPA LR+ L +RLA + Sbjct: 6 PVQPSLDDLLGRIVRDDVRAMGAYHVPDASGMVKLDAMENPYHLPAMLRDALGKRLAEVA 65 Query: 68 LNRYPVPAYTALKAAICKRLGVPAGYDVLLGNGSDELIALLSVACAQPGRTILAPEPGFV 127 LNRYPVP ALKA + + + VPAG DVLLGNGSDE+I+L+++A A+PG T+LAP PGFV Sbjct: 66 LNRYPVPTADALKAQLKRVMRVPAGADVLLGNGSDEIISLIAIAAAKPGATVLAPVPGFV 125 Query: 128 MYGVSAKMAGLEYVGVPLRADLSLDLPAMLAAMEAHKPVITWLGYPNNPTGTLYEMADV- 186 MY +SA++ GL++VGVPLRADL+LD AMLAAM H+P + +L YPNNPTG L++ AD+ Sbjct: 126 MYAMSAQLMGLKFVGVPLRADLTLDREAMLAAMAEHQPAVIYLAYPNNPTGNLFDAADMD 185 Query: 187 --LRIVEAAAPYGLVVVDEAYQPFAASTLMPALPQHNNLVLMRTVSKLGLAGIRLGYLSA 244 LR LVVVDEAYQPFA + MP LP+ ++L++MRTVSKLGLAGIRLGY++ Sbjct: 186 ALLRAARGPVCQSLVVVDEAYQPFAQHSWMPRLPEFDHLLVMRTVSKLGLAGIRLGYVAG 245 Query: 245 APALLRELDKVRPPYNVNVLTEAAALFVLEHLDVLQAQAARLRQARSALAAELAALDGVQ 304 P + ELDKVRPPYNVNVLTEA A FVL+H+DVL AQAA LR R+ L L+A GV Sbjct: 246 HPKWIAELDKVRPPYNVNVLTEATAAFVLDHVDVLDAQAATLRAERTRLIDALSAQPGVT 305 Query: 305 VFPSAANFLLIRVPGADKVCASLLAHRVLVKNAGRMHVLLQNCLRITVSSDEENAMFLAA 364 VFPSAANFLL+RVP A + LL RVLVKN +MH LL NCLR+TVS+ EENA FL A Sbjct: 306 VFPSAANFLLLRVPDAAGLFERLLKRRVLVKNVSKMHPLLANCLRVTVSNPEENAQFLDA 365 Query: 365 LKTALRE 371 +L++ Sbjct: 366 FAASLQD 372 >NMA1771 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase NmA Neisseria meningitidis Z2491 Length = 365 Score = 273 bits (699), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 145/355 (40%), Positives = 216/355 (60%), Gaps = 8/355 (2%) Query: 17 IANVIRPVVRGWQSYHVPSAE-GMVKLDAMENPYLLPAELREQLAQ----RLAALELNRY 71 + + IR ++ +Y + G KLD+ME+P + P E L Q RLAA ++ Y Sbjct: 4 VRSFIRDDIQAMSAYQIADVPPGFAKLDSMESP-VHPFAGHETLLQEWQARLAAAPIHLY 62 Query: 72 PVPAYTALKAAICKRLGVPAGYDVLLGNGSDELIALLSVACAQPGRTILAPEPGFVMYGV 131 P P+ + L+ A+ +P D+ LGNGSDELI +++ A+PG +LA EP FVMY Sbjct: 63 PNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITMLTAKPGAAMLAAEPSFVMYRH 122 Query: 132 SAKMAGLEYVGVPLRADLSLDLPAMLAAMEAHKPVITWLGYPNNPTGTLYEMADVLRIVE 191 +A + G++YVGVPL D +L+LPA+L A+ H+P +T++ YPNNPTG + A++ ++E Sbjct: 123 NAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTFIAYPNNPTGVCFTRAEIEAVIE 182 Query: 192 AAAPYGLVVVDEAYQPFAASTLMPALPQHNNLVLMRTVSKLGLAGIRLGYLSAAPALLRE 251 A+ G+VVVDEAY F + +P NL++MRTVSK+G AG+R+GY + P ++ E Sbjct: 183 ASD--GIVVVDEAYGAFNGDSFLPQAGSIPNLIVMRTVSKIGFAGLRIGYAAGCPEVIGE 240 Query: 252 LDKVRPPYNVNVLTEAAALFVLEHLDVLQAQAARLRQARSALAAELAALDGVQVFPSAAN 311 L K+ PPYN+N L+ A L+H ++ A L+ R + AEL + + FPS AN Sbjct: 241 LQKILPPYNMNQLSLTTAKLALQHYGIISANIDSLKNERERMFAELGKICRLNTFPSQAN 300 Query: 312 FLLIRVPGADKVCASLLAHRVLVKNAGRMHVLLQNCLRITVSSDEENAMFLAALK 366 F+ IRVP AD + +L +R+LVK H LL++CLRITV S +N L ++ Sbjct: 301 FITIRVPDADLLFDTLKQNRILVKKLHGAHPLLEHCLRITVGSPAQNDAVLNIIR 355 >NMB1582 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Nme Neisseria meningitidis MC58 Length = 365 Score = 266 bits (681), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 142/355 (40%), Positives = 215/355 (60%), Gaps = 8/355 (2%) Query: 17 IANVIRPVVRGWQSYHVPSAE-GMVKLDAMENPYLLPAELREQLAQ----RLAALELNRY 71 + + IR ++ +Y + G KLD+ME+P + P E L Q RLAA ++ Y Sbjct: 4 VRSFIRDDIQAMSAYQIADVPPGFAKLDSMESP-VHPFAGHETLLQEWQARLAAAPIHLY 62 Query: 72 PVPAYTALKAAICKRLGVPAGYDVLLGNGSDELIALLSVACAQPGRTILAPEPGFVMYGV 131 P P+ + L+ A+ +P D+ LGNGSDELI +++ A+PG +LA EP FVMY Sbjct: 63 PNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITMLTAKPGAAMLAAEPSFVMYRH 122 Query: 132 SAKMAGLEYVGVPLRADLSLDLPAMLAAMEAHKPVITWLGYPNNPTGTLYEMADVLRIVE 191 +A + G++YVGVPL D +L+LPA+L A+ H+P +T++ YPNNPTG + A++ ++E Sbjct: 123 NAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTFIAYPNNPTGVCFTRAEIEAVIE 182 Query: 192 AAAPYGLVVVDEAYQPFAASTLMPALPQHNNLVLMRTVSKLGLAGIRLGYLSAAPALLRE 251 A+ G+VVVDEAY F + +P + NL+++RT+SK+G AG+R+GY + P ++ E Sbjct: 183 ASD--GIVVVDEAYGAFNGDSFLPQAGRIPNLIVLRTLSKIGFAGLRIGYAAGCPEVIGE 240 Query: 252 LDKVRPPYNVNVLTEAAALFVLEHLDVLQAQAARLRQARSALAAELAALDGVQVFPSAAN 311 L K+ PPYN+N L+ A L H ++ A L+ R + AEL + + F S AN Sbjct: 241 LQKILPPYNMNQLSLTTAKLALRHYGIISANIDSLKNERERMFAELGKICRLNTFSSQAN 300 Query: 312 FLLIRVPGADKVCASLLAHRVLVKNAGRMHVLLQNCLRITVSSDEENAMFLAALK 366 F+ IRVP AD + +L +R+LVK H LL++CLRITV S +N L ++ Sbjct: 301 FITIRVPDADLLFDTLKQNRILVKKLHGAHPLLEHCLRITVGSPAQNDAVLNIIR 355 >aq_2084 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Aae Aquifex aeolicus Length = 354 Score = 216 bits (550), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 122/350 (34%), Positives = 191/350 (54%), Gaps = 7/350 (2%) Query: 25 VRGWQSYHVPSAEGMVKLDAMENPYLLPAELREQLAQRLAALELNRYPVPAYTALKAAIC 84 ++ ++Y V+L + E PY P E++++ + L + LN+YP P LKA + Sbjct: 6 IKELEAYKTEVTPASVRLSSNEFPYDFPEEIKQRALEELKKVPLNKYPDPEAKELKAVLA 65 Query: 85 KRLGVPAGYDVLLGNGSDELIALLSVACAQPGRTILAPEPGFVMYGVSAKMAGLEYVGVP 144 GV +++LGNGSDELI LS+A + + P P F MY +SAK+ G V V Sbjct: 66 DFFGVKEE-NLVLGNGSDELIYYLSIAIGELYIPVYIPVPTFPMYEISAKVLGRPLVKVQ 124 Query: 145 LRADLSLDLPAMLAAMEAHKPVITWLGYPNNPTGTLYEMADVLRIVEAAAPYGLVVVDEA 204 L + +DL + +E KPV+ + YPNNPTG L+ + I V+DEA Sbjct: 125 LDENFDIDLERSIELIEKEKPVLGYFAYPNNPTGNLFSRGKIEEIRNRGV---FCVIDEA 181 Query: 205 YQPFAASTLMPALPQHNNLVLMRTVSKLGLAGIRLGYLSAAPALLRELDKVRPPYNVNVL 264 Y ++ T + + + V++RT+SK+G+A +R+G L ++ E++KVR P+NV Sbjct: 182 YYHYSGETFLEDALKREDTVVLRTLSKIGMASLRVGILIGKGEIVSEINKVRLPFNVTYP 241 Query: 265 TEA-AALFVLEHLDVLQAQAARLRQARSALAAELAALDGVQVFPSAANFLLIRVPG-ADK 322 ++ A + + E + L + + + R + E+ ++GV+VFPS ANFLL R P A + Sbjct: 242 SQVMAKVLLTEGREFLMEKIQEVVKERERMYDEMKKIEGVEVFPSKANFLLFRTPYPAHE 301 Query: 323 VCASLLAHRVLVKNAGRMHVLLQNCLRITVSSDEENAMFLAALKTALREL 372 V LL VLV+N M LQ CLR++V EEN FL AL+ +++ L Sbjct: 302 VYQELLKRDVLVRNVSYMEG-LQKCLRVSVGKPEENNKFLEALEESIKSL 350 >DR2461 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Dra Deinococcus radiodurans Length = 361 Score = 179 bits (453), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 121/347 (34%), Positives = 177/347 (51%), Gaps = 5/347 (1%) Query: 21 IRPVVRGWQSYHVPSAEGMVKLDAMENPYLLPAELREQLAQRLAALELNRYPVPAYTALK 80 +R VR +Y + KLD ENPY P EL+++ A+R+ A NRYP L+ Sbjct: 14 VRQAVRDIPAYPFTPIDVPYKLDQNENPYDFPPELKQKAAERMLAHPWNRYPDLHADTLR 73 Query: 81 AAICKRLGVPAGYDVLLGNGSDELIALLSVACAQPGRTILAPEPGFVMYGVSAKMAGLEY 140 AAI G A V++ GS+ LI +L+ G+T+L +P F +Y + A M G E Sbjct: 74 AAIAGYEGWDAA-GVVITPGSNVLIKILT-ELGGIGQTVLTTDPTFSVYTLEAAMLGAEL 131 Query: 141 VGVPLRADLSLDLPAMLAAMEAHKPVITWLGYPNNPTGTLYEMADVLRIVEAAAPYGLV- 199 V PL D SL + A L A+ AH P + ++ P+ PTG DV R+VE A G V Sbjct: 132 VLTPLNPDFSLPVEATLQALAAHAPGVFYVTQPHAPTGHSDRPEDVRRVVEVADRLGWVT 191 Query: 200 VVDEAYQPFAASTLMPALPQHNNLVLMRTVSK-LGLAGIRLGYLSAAPALLRELDKVRPP 258 V+DEAY +A + + +++ +RT SK GLAG+R GYL P L L K+ Sbjct: 192 VIDEAYSQYAGTDYRELVRAGKHVLSLRTFSKAWGLAGVRAGYLLTNPELAGHLQKLVSA 251 Query: 259 YNVNVLTEAAALFVLEHLDVLQAQAARLRQARSALAAELAALDGVQVFPSAANFLLIRVP 318 + +N LT+A LEH + ++ + A R + A + +FPS NF L++ P Sbjct: 252 FTINFLTQAVIETALEHPEYMRERVAEAIAERGRIYAAVQGHPTCTIFPSNTNFFLLKTP 311 Query: 319 GADKVCASLLAHRVLVKNAGRMHVLLQNCLRITVSSDEENAMFLAAL 365 AD LL H ++ + ++ L CLRI V + EN +AA+ Sbjct: 312 DADAAYRHLLEHGIVCRRQDKLRG-LDGCLRIAVGTPAENDALIAAI 357