BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0039.0096.p         (90 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

all4087 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolas...    70   2e-12
NMB0602 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolas...    69   3e-12
NMA0806 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolas...    69   4e-12
HI0961 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase...    67   1e-11
PA0656 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase...    62   3e-10

>all4087 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases Nos Nostoc sp. PCC 7120
          Length = 122

 Score = 69.7 bits (169), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 11/84 (13%)

Query: 1   VHFLIVPRQHVATLADCGEQHAAVLGKMLALAPRLAAEQGCGYGLDAEGKPSGGFKTIIN 60
           VH L++P+Q +A L+D      A+LG +L  A R+A E G             G++ +IN
Sbjct: 46  VHILVIPKQPLAKLSDADSHDHALLGHLLLTAKRVAQEAGL----------ENGYRVVIN 95

Query: 61  TGPDGGQEVYHLHMHVIGG-PHPW 83
            G DGGQ VYHLH+H++GG P  W
Sbjct: 96  NGNDGGQTVYHLHLHILGGRPMAW 119


>NMB0602 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases Nme Neisseria meningitidis MC58
          Length = 107

 Score = 68.9 bits (167), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 10/80 (12%)

Query: 1   VHFLIVPRQHVATLADCGEQHAAVLGKMLALAPRLAAEQGCGYGLDAEGKPSGGFKTIIN 60
           VH L++P+ H  +LA    +H  +LGKM+   P +A   G           + GFKT+IN
Sbjct: 37  VHLLLIPKVHFDSLAHAAPEHQMLLGKMMLKVPEIAKAAGL----------ADGFKTLIN 86

Query: 61  TGPDGGQEVYHLHMHVIGGP 80
           TG  GGQEV+HLH+H++G P
Sbjct: 87  TGKGGGQEVFHLHIHIMGTP 106


>NMA0806 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases NmA Neisseria meningitidis Z2491
          Length = 107

 Score = 68.6 bits (166), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 10/80 (12%)

Query: 1   VHFLIVPRQHVATLADCGEQHAAVLGKMLALAPRLAAEQGCGYGLDAEGKPSGGFKTIIN 60
           VH L++P+ H  +LA    +H  +LGKM+   P +A   G           + GFKT+IN
Sbjct: 37  VHLLLIPKVHFDSLAHAAPEHQPLLGKMMLKVPEIAKAAGL----------ADGFKTLIN 86

Query: 61  TGPDGGQEVYHLHMHVIGGP 80
           TG  GGQEV+HLH+H++G P
Sbjct: 87  TGKGGGQEVFHLHIHIMGTP 106


>HI0961 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases Hin Haemophilus influenzae
          Length = 130

 Score = 66.6 bits (161), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 9/78 (11%)

Query: 2   HFLIVPRQHVATLADCGEQHAAVLGKMLALAPRLAAEQGCGYGLDAEGKPSGGFKTIINT 61
           H LI+P + + T+ D  EQ    LG++ ++A +LA E+G             G++ I+N 
Sbjct: 53  HILIIPNKVIPTVNDVTEQDEVALGRLFSVAAKLAKEEGVA---------EDGYRLIVNC 103

Query: 62  GPDGGQEVYHLHMHVIGG 79
              GGQEV+HLHMH++GG
Sbjct: 104 NKHGGQEVFHLHMHLVGG 121


>PA0656 [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other
           HIT family hydrolases Pae Pseudomonas aeruginosa
          Length = 112

 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 32/78 (41%), Positives = 45/78 (57%), Gaps = 10/78 (12%)

Query: 1   VHFLIVPRQHVATLADCGEQHAAVLGKMLALAPRLAAEQGCGYGLDAEGKPSGGFKTIIN 60
           VHFL++P++H+ TL    E    + G +L  A RLA EQGC            GF+ ++N
Sbjct: 36  VHFLVIPKRHIPTLEHLTEADRPLAGHILFTAQRLAREQGC----------EEGFRVVMN 85

Query: 61  TGPDGGQEVYHLHMHVIG 78
               GGQ V+H+HMHV+G
Sbjct: 86  CNDLGGQTVHHIHMHVLG 103