BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0089.p (416 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM2167 [C] COG0277 FAD/FMN-containing dehydrogenases Sty Salmon... 493 e-139 dld [C] COG0277 FAD/FMN-containing dehydrogenases Eco Escherichi... 481 e-135 Zdld [C] COG0277 FAD/FMN-containing dehydrogenases EcZ Escherich... 478 e-135 ECs3020 [C] COG0277 FAD/FMN-containing dehydrogenases Ecs Escher... 478 e-135 YPO1177 [C] COG0277 FAD/FMN-containing dehydrogenases Ype Yersin... 453 e-127 >STM2167 [C] COG0277 FAD/FMN-containing dehydrogenases Sty Salmonella typhimurium LT2 Length = 576 Score = 493 bits (1268), Expect = e-139, Method: Compositional matrix adjust. Identities = 241/403 (59%), Positives = 301/403 (74%), Gaps = 5/403 (1%) Query: 2 AITMTMERRTMDVISKLEAIVGSKHVLTGDAQTRRFRQGLRYGGGEVLAVVRPGRLLEMW 61 +ITMT + ++ +++L VG H+LT A+T R+R+G R G G+ LAVV PG LLE+W Sbjct: 3 SITMTDNKTFLNELARL---VGHSHLLTDPAKTARYRKGFRSGQGDALAVVFPGSLLELW 59 Query: 62 RVLQVCHAANMVIICQAANTGLTGGSTPIAEGYDRPVVLINTMRLTRLELLDQGQQVLSQ 121 RVL C A+ +I+ QAANTGLT GSTP YDR +V+I+T RL +L LLD GQQVL+ Sbjct: 60 RVLNACVNADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTQRLDKLHLLDNGQQVLAW 119 Query: 122 PGVTLDQLERRLKPLGREPHSVIGSSCIGASITGGICNNSGGSLIQRGPAYTQYALFARI 181 PG TL LE+ LKPLGREPHSVIGSSCIGAS+ GGICNNSGGSL+QRGPAYT+ +LFARI Sbjct: 120 PGTTLYALEKALKPLGREPHSVIGSSCIGASVIGGICNNSGGSLVQRGPAYTEMSLFARI 179 Query: 182 DEQGRLELVNHLGIDLGEDPERILQQLDAGHIDPALVHHVPGQMASDREYADHVRDISSP 241 D+QG+L+LVNHLGIDLG PE+IL +LD I V H G+ A D +Y VRDI++ Sbjct: 180 DDQGKLQLVNHLGIDLGHTPEQILSKLDDERIKDEDVRH-DGRHAHDHDYVTRVRDINAD 238 Query: 242 VPARFNADPRRLYEASGSAGKIAVFALRLDTFAADQVTQVFYIGANDPAVLEDLRRHILS 301 PAR+NADP RL+E+SG AGK+AVFA+RLDTFAA++ QVFYIG N PAVL ++RRHIL+ Sbjct: 239 TPARYNADPDRLFESSGCAGKLAVFAVRLDTFAAEKNQQVFYIGTNQPAVLTEIRRHILA 298 Query: 302 NFRALPIAGEYMHRSGYDLARKYGKDLFLYIRKAGTDKVPLAFALKSRFDALTEKLGLGR 361 NF LP+AGEYMHR YD+A +YGKD FL I K GTDK+P F LK R DA+ EK+ R Sbjct: 299 NFDNLPVAGEYMHRDIYDIAEQYGKDTFLMIDKLGTDKMPFFFTLKGRTDAMLEKVKFFR 358 Query: 362 -SLSDRLLQALADRLPAHLPPRLEDMRDRYAHHLLLKMGDEGI 403 +DR +Q P+HLPPR+++ RD+Y HHLLLKM +G+ Sbjct: 359 PHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHLLLKMAGDGV 401 >dld [C] COG0277 FAD/FMN-containing dehydrogenases Eco Escherichia coli K12 Length = 571 Score = 481 bits (1238), Expect = e-135, Method: Compositional matrix adjust. Identities = 235/391 (60%), Positives = 293/391 (74%), Gaps = 2/391 (0%) Query: 14 VISKLEAIVGSKHVLTGDAQTRRFRQGLRYGGGEVLAVVRPGRLLEMWRVLQVCHAANMV 73 +++L +VGS H+LT A+T R+R+G R G G+ LAVV PG LLE+WRVL+ C A+ + Sbjct: 12 FLNELARLVGSSHLLTDPAKTARYRKGFRSGQGDALAVVFPGSLLELWRVLKACVTADKI 71 Query: 74 IICQAANTGLTGGSTPIAEGYDRPVVLINTMRLTRLELLDQGQQVLSQPGVTLDQLERRL 133 I+ QAANTGLT GSTP YDR VV+I+T+RL +L +L +G+QVL+ PG TL LE+ L Sbjct: 72 ILMQAANTGLTEGSTPNGNDYDRDVVIISTLRLDKLHVLGKGEQVLAYPGTTLYSLEKAL 131 Query: 134 KPLGREPHSVIGSSCIGASITGGICNNSGGSLIQRGPAYTQYALFARIDEQGRLELVNHL 193 KPLGREPHSVIGSSCIGAS+ GGICNNSGGSL+QRGPAYT+ +LFARI+E G+L LVNHL Sbjct: 132 KPLGREPHSVIGSSCIGASVIGGICNNSGGSLVQRGPAYTEMSLFARINEDGKLTLVNHL 191 Query: 194 GIDLGEDPERILQQLDAGHIDPALVHHVPGQMASDREYADHVRDISSPVPARFNADPRRL 253 GIDLGE PE+IL +LD I V H G+ A D +Y VRDI + PAR+NADP RL Sbjct: 192 GIDLGETPEQILSKLDDDRIKDDDVRH-DGRHAHDYDYVHRVRDIEADTPARYNADPDRL 250 Query: 254 YEASGSAGKIAVFALRLDTFAADQVTQVFYIGANDPAVLEDLRRHILSNFRALPIAGEYM 313 +E+SG AGK+AVFA+RLDTF A++ QVFYIG N P VL ++RRHIL+NF LP+AGEYM Sbjct: 251 FESSGCAGKLAVFAVRLDTFEAEKNQQVFYIGTNQPEVLTEIRRHILANFENLPVAGEYM 310 Query: 314 HRSGYDLARKYGKDLFLYIRKAGTDKVPLAFALKSRFDALTEKLGLGR-SLSDRLLQALA 372 HR YD+A KYGKD FL I K GTDK+P F LK R DA+ EK+ R +DR +Q Sbjct: 311 HRDIYDIAEKYGKDTFLMIDKLGTDKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFG 370 Query: 373 DRLPAHLPPRLEDMRDRYAHHLLLKMGDEGI 403 P+HLPPR+++ RD+Y HHLLLKM +G+ Sbjct: 371 HLFPSHLPPRMKNWRDKYEHHLLLKMAGDGV 401 >Zdld [C] COG0277 FAD/FMN-containing dehydrogenases EcZ Escherichia coli O157:H7 EDL933 Length = 571 Score = 478 bits (1231), Expect = e-135, Method: Compositional matrix adjust. Identities = 233/391 (59%), Positives = 292/391 (74%), Gaps = 2/391 (0%) Query: 14 VISKLEAIVGSKHVLTGDAQTRRFRQGLRYGGGEVLAVVRPGRLLEMWRVLQVCHAANMV 73 +++L +VG H+LT A+T R+R+G R G G+ LAVV PG LLE+WRVL+ C A+ + Sbjct: 12 FLNELARLVGHSHLLTDPAKTARYRKGFRSGHGDALAVVFPGSLLELWRVLKACVTADKI 71 Query: 74 IICQAANTGLTGGSTPIAEGYDRPVVLINTMRLTRLELLDQGQQVLSQPGVTLDQLERRL 133 I+ QAANTGLT GSTP YDR +V+I+T+RL +L +L +G+QVL+ PG TL LE+ L Sbjct: 72 ILMQAANTGLTEGSTPNGNDYDRDIVIISTLRLDKLHVLGKGEQVLAYPGTTLYSLEKAL 131 Query: 134 KPLGREPHSVIGSSCIGASITGGICNNSGGSLIQRGPAYTQYALFARIDEQGRLELVNHL 193 KPLGREPHSVIGSSCIGAS+ GGICNNSGGSL+QRGPAYT+ +LFARI+E G+L LVNHL Sbjct: 132 KPLGREPHSVIGSSCIGASVIGGICNNSGGSLVQRGPAYTEMSLFARINEDGKLTLVNHL 191 Query: 194 GIDLGEDPERILQQLDAGHIDPALVHHVPGQMASDREYADHVRDISSPVPARFNADPRRL 253 GIDLGE PE+IL +LD I V H G+ A D +Y VRDI + PAR+NADP RL Sbjct: 192 GIDLGETPEQILSKLDDDRIKDDDVRH-DGRHAHDYDYVHRVRDIEADTPARYNADPDRL 250 Query: 254 YEASGSAGKIAVFALRLDTFAADQVTQVFYIGANDPAVLEDLRRHILSNFRALPIAGEYM 313 +E+SG AGK+AVFA+RLDTF A++ QVFYIG N P VL ++RRHIL+NF LP+AGEYM Sbjct: 251 FESSGCAGKLAVFAVRLDTFEAEKNQQVFYIGTNQPEVLTEIRRHILANFENLPVAGEYM 310 Query: 314 HRSGYDLARKYGKDLFLYIRKAGTDKVPLAFALKSRFDALTEKLGLGR-SLSDRLLQALA 372 HR YD+A KYGKD FL I K GTDK+P F LK R DA+ EK+ R +DR +Q Sbjct: 311 HRDIYDIAEKYGKDTFLMIDKLGTDKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFG 370 Query: 373 DRLPAHLPPRLEDMRDRYAHHLLLKMGDEGI 403 P+HLPPR+++ RD+Y HHLLLKM +G+ Sbjct: 371 HLFPSHLPPRMKNWRDKYEHHLLLKMAGDGV 401 >ECs3020 [C] COG0277 FAD/FMN-containing dehydrogenases Ecs Escherichia coli O157:H7 Length = 571 Score = 478 bits (1231), Expect = e-135, Method: Compositional matrix adjust. Identities = 233/391 (59%), Positives = 292/391 (74%), Gaps = 2/391 (0%) Query: 14 VISKLEAIVGSKHVLTGDAQTRRFRQGLRYGGGEVLAVVRPGRLLEMWRVLQVCHAANMV 73 +++L +VG H+LT A+T R+R+G R G G+ LAVV PG LLE+WRVL+ C A+ + Sbjct: 12 FLNELARLVGHSHLLTDPAKTARYRKGFRSGHGDALAVVFPGSLLELWRVLKACVTADKI 71 Query: 74 IICQAANTGLTGGSTPIAEGYDRPVVLINTMRLTRLELLDQGQQVLSQPGVTLDQLERRL 133 I+ QAANTGLT GSTP YDR +V+I+T+RL +L +L +G+QVL+ PG TL LE+ L Sbjct: 72 ILMQAANTGLTEGSTPNGNDYDRDIVIISTLRLDKLHVLGKGEQVLAYPGTTLYSLEKAL 131 Query: 134 KPLGREPHSVIGSSCIGASITGGICNNSGGSLIQRGPAYTQYALFARIDEQGRLELVNHL 193 KPLGREPHSVIGSSCIGAS+ GGICNNSGGSL+QRGPAYT+ +LFARI+E G+L LVNHL Sbjct: 132 KPLGREPHSVIGSSCIGASVIGGICNNSGGSLVQRGPAYTEMSLFARINEDGKLTLVNHL 191 Query: 194 GIDLGEDPERILQQLDAGHIDPALVHHVPGQMASDREYADHVRDISSPVPARFNADPRRL 253 GIDLGE PE+IL +LD I V H G+ A D +Y VRDI + PAR+NADP RL Sbjct: 192 GIDLGETPEQILSKLDDDRIKDDDVRH-DGRHAHDYDYVHRVRDIEADTPARYNADPDRL 250 Query: 254 YEASGSAGKIAVFALRLDTFAADQVTQVFYIGANDPAVLEDLRRHILSNFRALPIAGEYM 313 +E+SG AGK+AVFA+RLDTF A++ QVFYIG N P VL ++RRHIL+NF LP+AGEYM Sbjct: 251 FESSGCAGKLAVFAVRLDTFEAEKNQQVFYIGTNQPEVLTEIRRHILANFENLPVAGEYM 310 Query: 314 HRSGYDLARKYGKDLFLYIRKAGTDKVPLAFALKSRFDALTEKLGLGR-SLSDRLLQALA 372 HR YD+A KYGKD FL I K GTDK+P F LK R DA+ EK+ R +DR +Q Sbjct: 311 HRDIYDIAEKYGKDTFLMIDKLGTDKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFG 370 Query: 373 DRLPAHLPPRLEDMRDRYAHHLLLKMGDEGI 403 P+HLPPR+++ RD+Y HHLLLKM +G+ Sbjct: 371 HLFPSHLPPRMKNWRDKYEHHLLLKMAGDGV 401 >YPO1177 [C] COG0277 FAD/FMN-containing dehydrogenases Ype Yersinia pestis Length = 571 Score = 453 bits (1165), Expect = e-127, Method: Compositional matrix adjust. Identities = 226/391 (57%), Positives = 291/391 (74%), Gaps = 2/391 (0%) Query: 14 VISKLEAIVGSKHVLTGDAQTRRFRQGLRYGGGEVLAVVRPGRLLEMWRVLQVCHAANMV 73 ++++L+ IVG++++LTG+ QT R+R G R G G LAVV P LL+ W++LQ C AA+ + Sbjct: 13 LLTQLQHIVGTRYLLTGERQTERYRTGFRSGKGVALAVVFPSTLLQQWQLLQACVAADTI 72 Query: 74 IICQAANTGLTGGSTPIAEGYDRPVVLINTMRLTRLELLDQGQQVLSQPGVTLDQLERRL 133 II QAANTGLT GSTP + YDRP+V++NT+RL ++LLD G+QV+ PG TL+QLE+RL Sbjct: 73 IIMQAANTGLTEGSTPSGDDYDRPIVILNTLRLNNIQLLDDGKQVIGFPGSTLNQLEKRL 132 Query: 134 KPLGREPHSVIGSSCIGASITGGICNNSGGSLIQRGPAYTQYALFARIDEQGRLELVNHL 193 KP GREPHSVIGSSCIGAS+ GGICNNSGGSL+QRGPAYT+ AL+A+ID QG L+L+NHL Sbjct: 133 KPYGREPHSVIGSSCIGASVVGGICNNSGGSLVQRGPAYTEMALYAQIDAQGELQLINHL 192 Query: 194 GIDLGEDPERILQQLDAGHIDPALVHHVPGQMASDREYADHVRDISSPVPARFNADPRRL 253 GI LG PE ILQ+L+ G + GQ ASD EYA VRDI + P+RFNADPRRL Sbjct: 193 GISLGNTPEEILQRLEQGQYGAEDIEQT-GQQASDSEYATRVRDIDATTPSRFNADPRRL 251 Query: 254 YEASGSAGKIAVFALRLDTFAADQVTQVFYIGANDPAVLEDLRRHILSNFRALPIAGEYM 313 +EASG AGK+A+FA+RLDTF +++ QVFYIG N VL +LRR IL +F+ LPIAGEY+ Sbjct: 252 FEASGCAGKLAIFAVRLDTFPSEKQQQVFYIGTNQTQVLTELRRIILRDFKHLPIAGEYL 311 Query: 314 HRSGYDLARKYGKDLFLYIRKAGTDKVPLAFALKSRFDALTEKL-GLGRSLSDRLLQALA 372 HR +D+A YGKD F+ I GT+ +P F LK + DA K+ L L+DR++Q + Sbjct: 312 HRDIFDIAETYGKDTFVMINSMGTNNMPRFFTLKGKIDARLNKIPHLVDHLTDRVMQGFS 371 Query: 373 DRLPAHLPPRLEDMRDRYAHHLLLKMGDEGI 403 LP HLP RL+ R++Y HHLLLKM +GI Sbjct: 372 QILPNHLPKRLKTYRNQYEHHLLLKMSGDGI 402