BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0039.0024.p         (288 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

STM3175_2 [L] COG3449 DNA gyrase inhibitor Sty Salmonella typhim...   172   1e-42
STM3175_1 [K] COG2207 AraC-type DNA-binding domain-containing pr...   149   5e-36
Z4375 [L] COG3449 DNA gyrase inhibitor EcZ Escherichia coli O157...   143   5e-34
ECs3905 [L] COG3449 DNA gyrase inhibitor Ecs Escherichia coli O1...   143   5e-34
ygiV [L] COG3449 DNA gyrase inhibitor Eco Escherichia coli K12        141   2e-33

>STM3175_2 [L] COG3449 DNA gyrase inhibitor Sty Salmonella typhimurium LT2
          Length = 154

 Score =  172 bits (435), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 80/153 (52%), Positives = 107/153 (69%)

Query: 136 VEITHVEPIRIALLAHRGPVNALNATVAQFIAWRKASGLSPVERCRTFGLAWDNPDTTPP 195
           V+I    P R+A+L H G  + +NA+ A+FIAWR+ +G SP+   +TFG+AW +P TTPP
Sbjct: 2   VKIVEFPPTRVAMLTHLGHPDKVNASAAKFIAWRRETGQSPIASSQTFGIAWHDPQTTPP 61

Query: 196 EQFRFGICGELEGDLPGNAQGVVESLIPGGRCARVRHVGAHERLGDSIYPLYRQWLPESG 255
            QFRF ICG +   +  N  GVV S IPGGRCA VRH G+ + L +S++ L+R+WLP SG
Sbjct: 62  AQFRFDICGSVRQPIAENDVGVVNSEIPGGRCAVVRHQGSLDSLPESVWYLFREWLPASG 121

Query: 256 EELRDFPLYFHYLNLLPDTPPGELLTDIYLPLK 288
           E  RDFP++F YLN + +    ELLTDIYLPL+
Sbjct: 122 ETPRDFPVFFQYLNFVHEVAEHELLTDIYLPLR 154


>STM3175_1 [K] COG2207 AraC-type DNA-binding domain-containing proteins Sty
           Salmonella typhimurium LT2
          Length = 134

 Score =  149 bits (377), Expect = 5e-36,   Method: Compositional matrix adjust.
 Identities = 70/122 (57%), Positives = 92/122 (75%)

Query: 1   MSDERKKAYQARFERVLDHIEAHLHAPLEVEQLANVAHFSRFHFQRQFADFTGVGVARYI 60
           M+D    AY  R  RV DHIE HL  PL +E L+ +AH S FHF RQF  ++G+ + RYI
Sbjct: 1   MNDLISAAYSERLRRVCDHIERHLDEPLSIEALSRMAHSSPFHFHRQFTTWSGLPLYRYI 60

Query: 61  LLMRLKHASLQLAFQPQRRIIDIALEAGFENPESFTRAFRSAFGQSPSQFRRAPDWPSWH 120
             +RL+ AS +LAF PQ ++IDIAL+AGF+NPESFTRAF++AFGQSP +FR++PDW +WH
Sbjct: 61  QWLRLRRASWRLAFNPQDKVIDIALDAGFQNPESFTRAFKTAFGQSPRRFRQSPDWLAWH 120

Query: 121 ER 122
           +R
Sbjct: 121 QR 122


>Z4375 [L] COG3449 DNA gyrase inhibitor EcZ Escherichia coli O157:H7
           EDL933
          Length = 160

 Score =  143 bits (360), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 70/157 (44%), Positives = 95/157 (60%)

Query: 131 KVDVQVEITHVEPIRIALLAHRGPVNALNATVAQFIAWRKASGLSPVERCRTFGLAWDNP 190
            + + V I     I +A+L HR     LN +VA+FI WRK +GLSPV + +TFG+AWD+P
Sbjct: 3   NLTLDVNIIDFPSIPVAMLPHRCRPELLNYSVAKFIMWRKETGLSPVNQSQTFGVAWDDP 62

Query: 191 DTTPPEQFRFGICGELEGDLPGNAQGVVESLIPGGRCARVRHVGAHERLGDSIYPLYRQW 250
            TT PE FRF ICG +   +P N  GV    + GGR A  RHVG  + +  +I+ + R W
Sbjct: 63  ATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVARHVGELDDISHTIWGIIRHW 122

Query: 251 LPESGEELRDFPLYFHYLNLLPDTPPGELLTDIYLPL 287
           LP SGE++R  P+ FHY NL        L T++Y+PL
Sbjct: 123 LPASGEKMRKAPILFHYTNLAEGVTEQRLETNVYVPL 159


>ECs3905 [L] COG3449 DNA gyrase inhibitor Ecs Escherichia coli O157:H7
          Length = 160

 Score =  143 bits (360), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 70/157 (44%), Positives = 95/157 (60%)

Query: 131 KVDVQVEITHVEPIRIALLAHRGPVNALNATVAQFIAWRKASGLSPVERCRTFGLAWDNP 190
            + + V I     I +A+L HR     LN +VA+FI WRK +GLSPV + +TFG+AWD+P
Sbjct: 3   NLTLDVNIIDFPSIPVAMLPHRCRPELLNYSVAKFIMWRKETGLSPVNQSQTFGVAWDDP 62

Query: 191 DTTPPEQFRFGICGELEGDLPGNAQGVVESLIPGGRCARVRHVGAHERLGDSIYPLYRQW 250
            TT PE FRF ICG +   +P N  GV    + GGR A  RHVG  + +  +I+ + R W
Sbjct: 63  ATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVARHVGELDDISHTIWGIIRHW 122

Query: 251 LPESGEELRDFPLYFHYLNLLPDTPPGELLTDIYLPL 287
           LP SGE++R  P+ FHY NL        L T++Y+PL
Sbjct: 123 LPASGEKMRKAPILFHYTNLAEGVTEQRLETNVYVPL 159


>ygiV [L] COG3449 DNA gyrase inhibitor Eco Escherichia coli K12
          Length = 160

 Score =  141 bits (355), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 68/157 (43%), Positives = 94/157 (59%)

Query: 131 KVDVQVEITHVEPIRIALLAHRGPVNALNATVAQFIAWRKASGLSPVERCRTFGLAWDNP 190
            + + V I     I +A+L HR     LN +VA+FI WRK +GLSPV + +TFG+AWD+P
Sbjct: 3   NLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKETGLSPVNQSQTFGVAWDDP 62

Query: 191 DTTPPEQFRFGICGELEGDLPGNAQGVVESLIPGGRCARVRHVGAHERLGDSIYPLYRQW 250
            TT PE FRF ICG +   +P N  GV    + GGR A  R +G  + +  +++ + R W
Sbjct: 63  ATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVARQLGELDDISHTVWGIIRHW 122

Query: 251 LPESGEELRDFPLYFHYLNLLPDTPPGELLTDIYLPL 287
           LP SGE++R  P+ FHY NL        L TD+Y+PL
Sbjct: 123 LPASGEKMRKAPILFHYTNLAEGVTEQRLETDVYVPL 159