BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0038.0030.p (330 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0576 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NC... 375 e-104 NMB1019 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NC... 280 3e-75 NMA1245 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NC... 273 5e-73 AGl2157 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NC... 247 3e-65 BMEI0295 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (N... 240 4e-63 >RSc0576 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Rso Ralstonia solanacearum Length = 413 Score = 375 bits (964), Expect = e-104, Method: Compositional matrix adjust. Identities = 192/322 (59%), Positives = 230/322 (71%), Gaps = 5/322 (1%) Query: 8 CAAITTEFENVSAKSLATLAA-QTFVAPAASGVSIAQDRTAEKAFFTECGSQSGVLPAPH 66 C A+TTEFENV A++L L FVAP A VSIAQ+R AEK FF C +++G+ PAP Sbjct: 91 CPAVTTEFENVPAQALDRLEHLGAFVAPRAHCVSIAQNRIAEKKFFALCAARTGIHPAPS 150 Query: 67 LVINSEADIEGLDANLLPGILKTARMGYDGKGQVRVRSIEEVRAAFASMGGVTCVLEKML 126 VI +ADI+ L A+LLPGILK ARMGYDGKGQ RV ++ E+RAA+ +M V CVLEKML Sbjct: 151 WVIEHDADIDQLPADLLPGILKIARMGYDGKGQARVSTVGELRAAWGAMQHVPCVLEKML 210 Query: 127 PLAYEVSVLVARGHDGQAVVYPIAENVHRDGILFTTTVPGPNIKADAAARAQQAALQIIG 186 PLAYEVSVL AR DG V +P+AEN+HRDGILF+T +P ++ D A R + AA I Sbjct: 211 PLAYEVSVLAARAADGSTVTWPLAENIHRDGILFSTVMPSRSVSDDIATRTRAAAAMITE 270 Query: 187 ALQYVGVLCIEFFVLEDGALVVNEMAPRPHNSGHYTIDACVTSQFEQQARAMARLPXPLG 246 + YVGVLCIEFFVL+DG+L+ NEMAPRPHNSGH T+D C TSQFEQQ R MARL PLG Sbjct: 271 EMGYVGVLCIEFFVLQDGSLIANEMAPRPHNSGHITMDVCETSQFEQQVRTMARL--PLG 328 Query: 247 DTRQHSPSVMLNILGDVWYEGDTDAQREPAWDQVLALPGAHVHLYGKAEARRGRKMGHVT 306 TRQHSP MLN+LGDVW+E +R PAW V+ G VHLYGKA+AR GRKMGHV Sbjct: 329 STRQHSPGRMLNVLGDVWFE--YGLERTPAWHDVMRHSGTKVHLYGKADARPGRKMGHVN 386 Query: 307 FTGATLADAQQQLTAACAILGI 328 G + A + A +LG+ Sbjct: 387 CVGTSPEVADEAFHHAVQVLGL 408 >NMB1019 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nme Neisseria meningitidis MC58 Length = 378 Score = 280 bits (717), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 155/307 (50%), Positives = 200/307 (65%), Gaps = 13/307 (4%) Query: 1 LAELGALCAAITTEFENVSAKSLATLAAQTFVAPAASGVSIAQDRTAEKAFFTECGSQSG 60 L EL A CAA+TTEFENV+A ++ LA T V+P+ V+IAQ+R EKA+ + G Q+ Sbjct: 64 LDEL-AKCAAVTTEFENVNADAMRFLAKHTNVSPSGDCVAIAQNRIQEKAWIRKAGLQT- 121 Query: 61 VLPAPHLVINSEADIEGLDANLLPGILKTARMGYDGKGQVRVRSIEEVRAAFASMGGVTC 120 AP+ V+ DI A LPGILKTA +GYDGKGQ+RV++++E++AAFA GGV C Sbjct: 122 ---APYQVVCKAEDITEASAQFLPGILKTATLGYDGKGQIRVKTLDELKAAFAEHGGVDC 178 Query: 121 VLEKMLPLAYEVSVLVARGHDGQAVVYPIAENVHRDGILFTTTVPGPNIKADAAARAQQA 180 VLEKM+ L E+SV+V R ++ + AEN+H +GIL + VP + AD +A+Q Sbjct: 179 VLEKMVDLRSEISVIVCRLNNDNVQTFDPAENIHENGILAYSIVPA-RLSADVQQQARQM 237 Query: 181 ALQIIGALQYVGVLCIEFFVLEDG-ALVVNEMAPRPHNSGHYTIDACVTSQFEQQARAMA 239 A ++ L YVGVL +E FV+ D LVVNE+APRPHNSGH+TIDAC QF+QQ R M Sbjct: 238 AQRLADELDYVGVLAVEMFVVGDTHELVVNEIAPRPHNSGHHTIDACAADQFQQQVRIMC 297 Query: 240 RLPXPLGDTRQHSPSVMLNILGDVWYEGDTDAQREPAWDQVLALPGAHVHLYGKAEARRG 299 LP DT+ S M NILGDVW E EP W + + P AH+HLYGK A +G Sbjct: 298 NLPP--ADTKLLSSCCMANILGDVWQEDGG----EPDWLPLQSHPNAHLHLYGKKTAHKG 351 Query: 300 RKMGHVT 306 RKMGH T Sbjct: 352 RKMGHFT 358 >NMA1245 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) NmA Neisseria meningitidis Z2491 Length = 378 Score = 273 bits (697), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 152/308 (49%), Positives = 197/308 (63%), Gaps = 13/308 (4%) Query: 1 LAELGALCAAITTEFENVSAKSLATLAAQTFVAPAASGVSIAQDRTAEKAFFTECGSQSG 60 L EL A CAA+TTEFENV+A ++ LA T V+P+ V+IAQ+R EKA+ + G Q+ Sbjct: 64 LEEL-AKCAAVTTEFENVNADAMRFLAKHTNVSPSGDCVAIAQNRIQEKAWIRKAGLQT- 121 Query: 61 VLPAPHLVINSEADIEGLDANLLPGILKTARMGYDGKGQVRVRSIEEVRAAFASMGGVTC 120 AP+ I DI LPGILKTA +GYDGKGQ+RV++++E++AAFA GV C Sbjct: 122 ---APYQAICKAEDITEESIQFLPGILKTATLGYDGKGQIRVKTVDELKAAFAEHRGVDC 178 Query: 121 VLEKMLPLAYEVSVLVARGHDGQAVVYPIAENVHRDGILFTTTVPGPNIKADAAARAQQA 180 VLEKM+ L E+SV+V R ++ + AEN+H +GIL + VP + AD +A+Q Sbjct: 179 VLEKMVDLRGEISVIVCRLNNDNVQTFDPAENIHENGILAYSIVPA-RLSADIQQQARQM 237 Query: 181 ALQIIGALQYVGVLCIEFFVLEDG-ALVVNEMAPRPHNSGHYTIDACVTSQFEQQARAMA 239 A ++ L YVGVL +E FV+ D LVVNE+APRPHNSGH+T+DAC QF+QQ R M Sbjct: 238 AQRLADELNYVGVLAVEMFVVGDTHELVVNEIAPRPHNSGHHTVDACAADQFQQQVRLMC 297 Query: 240 RLPXPLGDTRQHSPSVMLNILGDVWYEGDTDAQREPAWDQVLALPGAHVHLYGKAEARRG 299 LP DT+ S M NILGDVW E EP W + + P AH+HLYGK A +G Sbjct: 298 NLPP--ADTKLLSSCCMANILGDVWQEDGG----EPDWFPLQSRPDAHLHLYGKKTAHKG 351 Query: 300 RKMGHVTF 307 RKMGH T Sbjct: 352 RKMGHFTI 359 >AGl2157 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 363 Score = 247 bits (630), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 145/307 (47%), Positives = 184/307 (59%), Gaps = 18/307 (5%) Query: 1 LAELGALCAAITTEFENVSAKSLATLAAQTFVAPAASGVSIAQDRTAEKAFFTECGSQSG 60 LAEL + C +T EFENV + L+A V P A +S +QDR EK F CG Sbjct: 66 LAELASRCDVVTYEFENVPVAAAEKLSASVPVYPPAQALSASQDRLTEKRFLNGCG---- 121 Query: 61 VLPAPHLVINSEADIEG-LDANLLPGILKTARMGYDGKGQVRVRSIEEVRAAFASMGGVT 119 + A ++S+ ++E L A G+LKT RMGYDGKGQ R E + AFA++GGV Sbjct: 122 IPTADFRAVDSQDELEAALTAFGGKGVLKTRRMGYDGKGQRLFRGGENLTGAFAALGGVP 181 Query: 120 CVLEKMLPLAYEVSVLVARGHDGQAVVYPIAENVHRDGILFTTTVPGPNIKADAAARAQQ 179 +LE + E+S++ AR DG Y AENVH +GIL T+TVP + A A A Q Sbjct: 182 LILESFVAFEREISIIAARFQDGTVTCYDPAENVHLNGILHTSTVPAA-LSDAAKAVAVQ 240 Query: 180 AALQIIGALQYVGVLCIEFFVLEDGALVVNEMAPRPHNSGHYTIDACVTSQFEQQARAMA 239 +A +++ AL+YVGV+ IEFFVL DG+LV NEMAPR HN+GH+T AC SQFEQ RA++ Sbjct: 241 SAEKLLAALEYVGVIGIEFFVLPDGSLVANEMAPRVHNTGHWTEAACAISQFEQHIRAVS 300 Query: 240 RLPXPLGDTRQHSPSVMLNILGDVWYEGDTDAQREPAWDQVLALPGAHVHLYGKAEARRG 299 L G T +HS VM N++GD D PAW L+ VHLYGK EAR G Sbjct: 301 DLAP--GSTDRHSDCVMTNLIGD-------DINDVPAW---LSKKDCLVHLYGKTEARPG 348 Query: 300 RKMGHVT 306 RKMGHVT Sbjct: 349 RKMGHVT 355 >BMEI0295 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Bme Brucella melitensis Length = 362 Score = 240 bits (612), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 149/309 (48%), Positives = 188/309 (60%), Gaps = 20/309 (6%) Query: 1 LAELGALCAAITTEFENVSAKSLATLAAQTFVAPAASGVSIAQDRTAEKAFFTECGSQSG 60 LAEL A IT EFENV + LA V P + + I+QDR EK F E SG Sbjct: 64 LAELAAASDVITYEFENVPVSAADKLAETALVLPPPAALEISQDRFTEKQFLNE----SG 119 Query: 61 VLPAP-HLVINSEADIEGLDANLLPGILKTARMGYDGKGQVRVRSIEEVRA--AFASMGG 117 + AP LV + E I L A GILK R+GYDGKGQVR+ S++E +A AFA++ Sbjct: 120 IETAPWRLVDDEETLIAALGALGGRGILKIRRLGYDGKGQVRLASLDETQACNAFAAINK 179 Query: 118 VTCVLEKMLPLAYEVSVLVARGHDGQAVVYPIAENVHRDGILFTTTVPGPNIKADAAARA 177 +LE + EVSV+ AR G ++ +AENVH+DGIL T+TVP I A A Sbjct: 180 APAILEGFVEFEREVSVIAARDRSGNVAIFDLAENVHKDGILATSTVPAA-ISVQTAEAA 238 Query: 178 QQAALQIIGALQYVGVLCIEFFVLEDGALVVNEMAPRPHNSGHYTIDACVTSQFEQQARA 237 + AA +++ AL YVGVL +EFFVL+DG L+ NE APR HNSGH+T AC SQFEQ RA Sbjct: 239 RTAAEKLLHALDYVGVLGLEFFVLKDGTLLANEFAPRVHNSGHWTEAACAISQFEQHIRA 298 Query: 238 MARLPXPLGDTRQHSPSVMLNILGDVWYEGDTDAQREPAWDQVLALPGAHVHLYGKAEAR 297 +A L PLG+T +HS VM N++GD D ++ PA +L A +HLYGK EAR Sbjct: 299 VAGL--PLGNTDRHSDCVMENLIGD-------DIEKVPA---ILCEKNAVLHLYGKKEAR 346 Query: 298 RGRKMGHVT 306 GRK+GHVT Sbjct: 347 AGRKIGHVT 355