BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0062.p (458 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0952 [LKJ] COG0513 Superfamily II DNA and RNA helicases Rso R... 527 e-149 NMB1368 [LKJ] COG0513 Superfamily II DNA and RNA helicases Nme N... 438 e-122 NMA1580 [LKJ] COG0513 Superfamily II DNA and RNA helicases NmA N... 437 e-122 RSc0539 [LKJ] COG0513 Superfamily II DNA and RNA helicases Rso R... 344 3e-94 STM0820 [LKJ] COG0513 Superfamily II DNA and RNA helicases Sty S... 342 1e-93 >RSc0952 [LKJ] COG0513 Superfamily II DNA and RNA helicases Rso Ralstonia solanacearum Length = 608 Score = 527 bits (1357), Expect = e-149, Method: Compositional matrix adjust. Identities = 258/406 (63%), Positives = 322/406 (79%), Gaps = 8/406 (1%) Query: 6 LGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSLHQLAD 65 LGL+ I +AL E YT PTPVQ +AIPA +SG+DLLV+SQTGSGKTAAFMLP++ ++++ Sbjct: 35 LGLDERIARALGELNYTQPTPVQAQAIPACLSGRDLLVTSQTGSGKTAAFMLPAIQRISE 94 Query: 66 LPPAPQAART--PNQERQASRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYGAYM 123 P PQ R P Q R +G RPR PA+P +LVLTPTRELALQVTTAT +YG ++ Sbjct: 95 QP-EPQRPRADGPQQ-----RVKGRRPRPAPAKPSLLVLTPTRELALQVTTATAQYGRHL 148 Query: 124 RRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEADRM 183 RR+ SILGGMPYPKQ+ +L+R P+I++ATPGRL+DH++SG+ID S L +LV DEADRM Sbjct: 149 RRIVCASILGGMPYPKQLDMLARMPDIIIATPGRLLDHIDSGRIDLSALDMLVFDEADRM 208 Query: 184 LDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPLTIQIASSSTRHENIM 243 LDMGF DDIE IV ATPA+RQ ++FSAT+D + +A+R+ P I+IA++ +I Sbjct: 209 LDMGFADDIEAIVGATPASRQMLMFSATMDRRIEQLAERMMREPQRIEIAAARIDQSHIE 268 Query: 244 QRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHGDMH 303 +R+HF DDLSHK +LLDHLLRD ++ QA++FTATKRDAD++A+RL GF+A ALHGDMH Sbjct: 269 ERLHFTDDLSHKQQLLDHLLRDATLKQAIVFTATKRDADSLAERLTETGFSAGALHGDMH 328 Query: 304 QGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTGRAG 363 QGARNRTL +LRRGQ+R+LVATDVAARGIDVP ITHV N+DLPK AEDYVHRIGRTGRAG Sbjct: 329 QGARNRTLTALRRGQLRVLVATDVAARGIDVPDITHVVNFDLPKQAEDYVHRIGRTGRAG 388 Query: 364 RNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEPKKSAAPRS 409 R+G+AI+LVNH + Q +RIERF + I VVEG EPK+S PRS Sbjct: 389 RSGIAINLVNHGDTFQWRRIERFVDRRIDATVVEGLEPKRSPKPRS 434 >NMB1368 [LKJ] COG0513 Superfamily II DNA and RNA helicases Nme Neisseria meningitidis MC58 Length = 462 Score = 438 bits (1127), Expect = e-122, Method: Compositional matrix adjust. Identities = 235/467 (50%), Positives = 304/467 (65%), Gaps = 40/467 (8%) Query: 1 MTFEALGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSL 60 + F L L+ +I+ A++ GY SPTP+Q +AIP A+ G+D++ S+QTGSGKTAAF+LP+L Sbjct: 3 IKFADLNLDKNILSAVSSEGYESPTPIQAQAIPFALEGRDIMASAQTGSGKTAAFLLPTL 62 Query: 61 HQLADLPPAPQAARTPNQERQASRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYG 120 +L R E+P P+ LVLTPTRELA QV Y Sbjct: 63 QKLT--------------------KRSEKP---GKGPRALVLTPTRELAAQVEKNALAYA 99 Query: 121 AYMRRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEA 180 MR R VSI+GG + Q + LS+ +++VATPGRL+D M+SGK+DF +L++L+LDEA Sbjct: 100 KNMRWFRTVSIVGGASFGYQTRALSKPVDLIVATPGRLMDLMQSGKVDFERLEVLILDEA 159 Query: 181 DRMLDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPLTIQIASSSTRHE 240 DRMLDMGFIDDIE IV ATP+ RQT+LFSAT DG VG +A+++T +P I++ + + Sbjct: 160 DRMLDMGFIDDIETIVEATPSDRQTLLFSATWDGAVGKLARKLTKDPEIIEVERVDDQGK 219 Query: 241 NIMQRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHG 300 I +++ + DD+ HKNRLLDH+LRD +IDQ VIFT+TK + IAD L GFAA LHG Sbjct: 220 -IEEQLLYCDDMRHKNRLLDHILRDANIDQCVIFTSTKAMTEVIADELYEKGFAANCLHG 278 Query: 301 DMHQGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTG 360 DM QG RNRTL LR+G+ ++LVATDVAARGIDVP ITHV NYDLPK AEDYVHRIGRTG Sbjct: 279 DMPQGWRNRTLMDLRKGRCKILVATDVAARGIDVPTITHVINYDLPKQAEDYVHRIGRTG 338 Query: 361 RAGRNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEP---KKSA-------APRSP 410 RAGR G+AI+ E ++V +IE++ + +P +EG EP +KSA Sbjct: 339 RAGRTGIAITFAEVNEYVKVHKIEKYINRKLPELTIEGMEPTRKRKSAGGKPKGKGGWGD 398 Query: 411 RKPGGWRPGDGRSNNGPRYGAGNREGGGHREG----GFGGNREGFLG 453 RK GGWR S G +G R G +EG GF EGF G Sbjct: 399 RKSGGWRGDHKPSKEG--FGGKTRGEGFKKEGFKRDGFKKTGEGFKG 443 >NMA1580 [LKJ] COG0513 Superfamily II DNA and RNA helicases NmA Neisseria meningitidis Z2491 Length = 462 Score = 437 bits (1124), Expect = e-122, Method: Compositional matrix adjust. Identities = 235/467 (50%), Positives = 303/467 (64%), Gaps = 40/467 (8%) Query: 1 MTFEALGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSL 60 + F L L+ +I+ A++ GY SPTP+Q +AIP A+ G+D++ S+QTGSGKTAAF+LP+L Sbjct: 3 IKFADLNLDKNILSAVSSEGYESPTPIQAQAIPFALEGRDIMASAQTGSGKTAAFLLPTL 62 Query: 61 HQLADLPPAPQAARTPNQERQASRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYG 120 +L R E+P P+ LVLTPTRELA QV Y Sbjct: 63 QRLT--------------------KRSEKP---GKGPRALVLTPTRELAAQVEKNALAYA 99 Query: 121 AYMRRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEA 180 MR R VSI+GG + Q + LS+ +++VATPGRL+D M+SGK+DF++L++L+LDEA Sbjct: 100 KNMRWFRTVSIVGGASFGYQTRALSKPVDLIVATPGRLMDLMQSGKVDFARLEVLILDEA 159 Query: 181 DRMLDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPLTIQIASSSTRHE 240 DRMLDMGFIDDIE IV ATP RQT+LFSAT DG VG +A+++T +P I++ + + Sbjct: 160 DRMLDMGFIDDIETIVEATPEDRQTLLFSATWDGAVGKLARKLTKDPEIIEVERVDDQGK 219 Query: 241 NIMQRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHG 300 I +++ + DD+ HKNRLLDH+LRD IDQ VIFT+TK + IAD L GFAA LHG Sbjct: 220 -IEEQLLYCDDMRHKNRLLDHILRDADIDQCVIFTSTKAMTEVIADELYEKGFAANCLHG 278 Query: 301 DMHQGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTG 360 DM QG RNRTL LR+G+ ++LVATDVAARGIDVP ITHV NYDLPK AEDYVHRIGRTG Sbjct: 279 DMPQGWRNRTLMDLRKGRCKILVATDVAARGIDVPTITHVINYDLPKQAEDYVHRIGRTG 338 Query: 361 RAGRNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEP---KKSA-------APRSP 410 RAGR G+AI+ E ++V +IE++ + +P +EG EP +KSA Sbjct: 339 RAGRTGIAITFAEVNEYVKVHKIEKYINRKLPELTIEGMEPTRKRKSAGGKPKGKGGWGD 398 Query: 411 RKPGGWRPGDGRSNNGPRYGAGNREGGGHREG----GFGGNREGFLG 453 RK GGWR S G +G R G +EG GF EGF G Sbjct: 399 RKSGGWRGDHKPSKEG--FGGKTRGEGFKKEGFKRDGFKKTGEGFKG 443 >RSc0539 [LKJ] COG0513 Superfamily II DNA and RNA helicases Rso Ralstonia solanacearum Length = 540 Score = 344 bits (882), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 199/440 (45%), Positives = 265/440 (60%), Gaps = 29/440 (6%) Query: 1 MTFEALGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSL 60 M+F LGL+ +++A+ E GY PTP+Q +AIPA + G DLL +QTG+GKTA F LP L Sbjct: 1 MSFSELGLSDKLVRAVAELGYAEPTPIQRQAIPAILKGGDLLAGAQTGTGKTAGFTLPLL 60 Query: 61 HQLADLPPAPQAARTPNQERQASRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYG 120 H+L+ + P +TP+ R RA LVLTPTRELA QV + YG Sbjct: 61 HRLSAV--QPNKVQTPHGMRYPIRA--------------LVLTPTRELAAQVEESVRAYG 104 Query: 121 AYMRRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEA 180 Y+ ++ + + GG+ Q+ L R +I+VATPGRL+DH+ ID S +++LVLDEA Sbjct: 105 KYLP-LKSMVMFGGVGINPQIDALKRGVDIVVATPGRLLDHVGQRTIDLSHIELLVLDEA 163 Query: 181 DRMLDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPLTIQIASSSTRHE 240 DRMLDMGFI DI KI+ P RQ +LFSAT + +A R+ + P I++A +T E Sbjct: 164 DRMLDMGFIHDIRKILNILPPKRQNLLFSATFSDDIRALADRLLDQPALIEVARRNTTAE 223 Query: 241 NIMQRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHG 300 + QR++ VD K LL L+ D Q ++FT TK A+ +A++L G A A+HG Sbjct: 224 TVEQRIYPVDR-ERKRELLAKLVSDNDWHQVLVFTRTKHGANRLAEQLTRDGIPALAIHG 282 Query: 301 DMHQGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTG 360 + Q AR R L+ + G +R+LVATD+AARGID+ + HV N+DLP EDYVHRIGRTG Sbjct: 283 NKSQSARTRALSEFKAGTLRVLVATDIAARGIDIDQLPHVVNFDLPNVPEDYVHRIGRTG 342 Query: 361 RAGRNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEPKKSAAPR-------SPRKP 413 RAG G AISLV E ++ IER K+ +P V+ GFEP + AP S R P Sbjct: 343 RAGAQGEAISLVCVDEHGLLRDIERLIKRELPRTVLAGFEPDPTIAPEPIPNGRNSARAP 402 Query: 414 GGWRPGDGRSNNGPRYGAGN 433 R G GRS PR AGN Sbjct: 403 ---RQGGGRSQP-PRQAAGN 418 >STM0820 [LKJ] COG0513 Superfamily II DNA and RNA helicases Sty Salmonella typhimurium LT2 Length = 454 Score = 342 bits (876), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 180/404 (44%), Positives = 248/404 (61%), Gaps = 23/404 (5%) Query: 1 MTFEALGLNPSIIKALTEAGYTSPTPVQEKAIPAAISGQDLLVSSQTGSGKTAAFMLPSL 60 M+F++LGLNP I++A+ E GY PTP+Q++AIPA + G+DL+ S+QTG+GKTA F LP L Sbjct: 1 MSFDSLGLNPDILRAIAEQGYREPTPIQQQAIPAVLEGRDLMASAQTGTGKTAGFTLPLL 60 Query: 61 HQLADLPPAPQAARTPNQERQASRARGERPRYQPAQPKMLVLTPTRELALQVTTATDKYG 120 L P A+G RP + L+LTPTRELA Q+ Y Sbjct: 61 QHLITHQP---------------HAKGRRP------VRALILTPTRELAAQIGENVRDYS 99 Query: 121 AYMRRVRVVSILGGMPYPKQMQLLSRNPEILVATPGRLIDHMESGKIDFSQLQILVLDEA 180 Y+ +R + + GG+ QM L ++LVATPGRL+D + Q++ILVLDEA Sbjct: 100 KYLN-IRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQIEILVLDEA 158 Query: 181 DRMLDMGFIDDIEKIVAATPATRQTMLFSATLDGVVGNMAKRITNNPLTIQIASSSTRHE 240 DRMLDMGFI DI +++A PA RQ +LFSAT + +A+++ NPL I++A +T E Sbjct: 159 DRMLDMGFIHDIRRVLAKLPAKRQNLLFSATFSDDIKALAEKLLRNPLEIEVARRNTASE 218 Query: 241 NIMQRVHFVDDLSHKNRLLDHLLRDTSIDQAVIFTATKRDADTIADRLNIAGFAAAALHG 300 + Q VHFVD K LL ++ + Q ++FT TK A+ +A++LN G +AA+HG Sbjct: 219 QVTQHVHFVDK-KRKRELLSQMIGQGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG 277 Query: 301 DMHQGARNRTLNSLRRGQVRMLVATDVAARGIDVPGITHVFNYDLPKFAEDYVHRIGRTG 360 + QGAR R L + G +R+LVATD+AARG+D+ + HV NY+LP EDYVHRIGRTG Sbjct: 278 NKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIGRTG 337 Query: 361 RAGRNGVAISLVNHAEGMQVKRIERFTKQTIPVDVVEGFEPKKS 404 RA G A+SLV E ++ IE+ K+ IP G+EP S Sbjct: 338 RAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRITTPGYEPDPS 381