BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0036.0033.p         (92 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0946 [H] COG0262 Dihydrofolate reductase Rso Ralstonia solana...   110   8e-25
BH3450 [H] COG0262 Dihydrofolate reductase Bha Bacillus halodurans    108   2e-24
BS_dfrA [H] COG0262 Dihydrofolate reductase Bsu Bacillus subtilis     100   2e-21
SA1259 [H] COG0262 Dihydrofolate reductase Sau Staphylococcus au...    96   2e-20
PA0350 [H] COG0262 Dihydrofolate reductase Pae Pseudomonas aerug...    93   1e-19

>RSc0946 [H] COG0262 Dihydrofolate reductase Rso Ralstonia solanacearum
          Length = 167

 Score =  110 bits (275), Expect = 8e-25,   Method: Compositional matrix adjust.
 Identities = 55/82 (67%), Positives = 64/82 (78%)

Query: 8  LTLIVATDLNNGIGINNTLPWRLPEDLAHFKRTTSGHAILMGRKTFDSIGRPLPNRRNIV 67
          LTLIVA   N  IG +NTLPWRLPEDLAHFKRTT G  I+MGRKT++SIGRPLP RRNIV
Sbjct: 4  LTLIVARARNGVIGRDNTLPWRLPEDLAHFKRTTMGAPIVMGRKTYESIGRPLPGRRNIV 63

Query: 68 ITRNAGWQHDGVETAGSLQEAR 89
          +TR+A     G E A SL++A+
Sbjct: 64 VTRSAKLALPGCEIAHSLEDAQ 85


>BH3450 [H] COG0262 Dihydrofolate reductase Bha Bacillus halodurans
          Length = 163

 Score =  108 bits (271), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 47/81 (58%), Positives = 62/81 (76%)

Query: 8  LTLIVATDLNNGIGINNTLPWRLPEDLAHFKRTTSGHAILMGRKTFDSIGRPLPNRRNIV 67
          ++ IVA D +  IG  N LPWRLP DLAHFKR TSGH ++MGRKT++SIG+PLPNRRN+V
Sbjct: 2  ISFIVAMDKHRLIGKENDLPWRLPADLAHFKRVTSGHTVIMGRKTYESIGKPLPNRRNVV 61

Query: 68 ITRNAGWQHDGVETAGSLQEA 88
          +TR+  +  +GV+   S+ EA
Sbjct: 62 VTRSQAYTAEGVDIVHSIDEA 82


>BS_dfrA [H] COG0262 Dihydrofolate reductase Bsu Bacillus subtilis
          Length = 168

 Score = 99.8 bits (247), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 44/81 (54%), Positives = 57/81 (70%)

Query: 8  LTLIVATDLNNGIGINNTLPWRLPEDLAHFKRTTSGHAILMGRKTFDSIGRPLPNRRNIV 67
          ++ I A D N  IG +N LPW LP DLA+FK+ TSGH+I+MGRKTF+SIGRPLPNR+NIV
Sbjct: 2  ISFIFAMDANRLIGKDNDLPWHLPNDLAYFKKITSGHSIIMGRKTFESIGRPLPNRKNIV 61

Query: 68 ITRNAGWQHDGVETAGSLQEA 88
          +T     +  G     SL++ 
Sbjct: 62 VTSAPDSEFQGCTVVSSLKDV 82


>SA1259 [H] COG0262 Dihydrofolate reductase Sau Staphylococcus aureus
          N315
          Length = 159

 Score = 95.9 bits (237), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 40/80 (50%), Positives = 59/80 (73%)

Query: 8  LTLIVATDLNNGIGINNTLPWRLPEDLAHFKRTTSGHAILMGRKTFDSIGRPLPNRRNIV 67
          L+++VA DL   IG  N LPW LP DL H K+ ++GH ++MGRKTF+SIG+PLPNRRN+V
Sbjct: 3  LSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVV 62

Query: 68 ITRNAGWQHDGVETAGSLQE 87
          +T +  +  +GV+   S+++
Sbjct: 63 LTSDTSFNVEGVDVIHSIED 82


>PA0350 [H] COG0262 Dihydrofolate reductase Pae Pseudomonas aeruginosa
          Length = 168

 Score = 93.2 bits (230), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 43/78 (55%), Positives = 53/78 (67%)

Query: 8  LTLIVATDLNNGIGINNTLPWRLPEDLAHFKRTTSGHAILMGRKTFDSIGRPLPNRRNIV 67
          L +I A   N  IGI+N LPWRLP DL HFK  T G  ++MGRKT+DS+GRPLP R N+V
Sbjct: 5  LAMIAALGENRAIGIDNRLPWRLPADLKHFKAMTLGKPVIMGRKTWDSLGRPLPGRLNLV 64

Query: 68 ITRNAGWQHDGVETAGSL 85
          ++R AG   +G E   SL
Sbjct: 65 VSRQAGLALEGAEVFASL 82