BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0036.0032.p         (71 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0946 [H] COG0262 Dihydrofolate reductase Rso Ralstonia solana...    83   1e-16
NMA2179 [H] COG0262 Dihydrofolate reductase NmA Neisseria mening...    67   1e-11
NMB0308 [H] COG0262 Dihydrofolate reductase Nme Neisseria mening...    66   2e-11
lin1987 [H] COG0262 Dihydrofolate reductase Lin Listeria innocua       59   2e-09
PA0350 [H] COG0262 Dihydrofolate reductase Pae Pseudomonas aerug...    59   2e-09

>RSc0946 [H] COG0262 Dihydrofolate reductase Rso Ralstonia solanacearum
          Length = 167

 Score = 83.2 bits (204), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 43/71 (60%), Positives = 48/71 (67%), Gaps = 1/71 (1%)

Query: 1   VETAGSIGGAQIYAEALPLADRLIITRIAQTFDCDAFFPALDQQVWQETAREEHHSETSG 60
           VE    IGGAQ+YA+ALP ADRLI+T I   F+ DA FPA D  VW E ARE HH+    
Sbjct: 91  VEQIFLIGGAQLYADALPSADRLIVTEIDADFEGDAHFPAPDPAVWHEVARETHHAAAPN 150

Query: 61  -LDYAFVTYER 70
             DYAFVTYER
Sbjct: 151 DFDYAFVTYER 161


>NMA2179 [H] COG0262 Dihydrofolate reductase NmA Neisseria meningitidis
           Z2491
          Length = 162

 Score = 66.6 bits (161), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 33/69 (47%), Positives = 43/69 (62%)

Query: 2   ETAGSIGGAQIYAEALPLADRLIITRIAQTFDCDAFFPALDQQVWQETAREEHHSETSGL 61
           E A  +GGAQIY +A+PLA  L IT +  + + DAFFPA+D+  W+E  R E    + G 
Sbjct: 93  EEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPAIDRTHWKEAERTERRVSSKGT 152

Query: 62  DYAFVTYER 70
            YAFV Y R
Sbjct: 153 SYAFVHYLR 161


>NMB0308 [H] COG0262 Dihydrofolate reductase Nme Neisseria meningitidis MC58
          Length = 162

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 33/69 (47%), Positives = 43/69 (62%)

Query: 2   ETAGSIGGAQIYAEALPLADRLIITRIAQTFDCDAFFPALDQQVWQETAREEHHSETSGL 61
           E A  +GGAQIY +A+PLA  L IT +  + + DAFFPA+D+  W+E  R E    + G 
Sbjct: 93  EEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPAIDRTHWKEAERTERRVSSKGT 152

Query: 62  DYAFVTYER 70
            YAFV Y R
Sbjct: 153 RYAFVHYLR 161


>lin1987 [H] COG0262 Dihydrofolate reductase Lin Listeria innocua
          Length = 160

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 28/66 (42%), Positives = 41/66 (62%), Gaps = 1/66 (1%)

Query: 7   IGGAQIYAEALPLADRLIITRIAQTFDCDAFFPALDQQVWQETAREEHHS-ETSGLDYAF 65
           +GGA+IY   + +AD+LI+T+I   FD D  FP +D + + E A+E H   E +  +Y F
Sbjct: 95  VGGAEIYRLFMDVADKLIVTKIDAEFDADTAFPEVDWENFSEVAKEPHEKDEKNKYNYTF 154

Query: 66  VTYERR 71
            TYER 
Sbjct: 155 YTYERN 160


>PA0350 [H] COG0262 Dihydrofolate reductase Pae Pseudomonas aeruginosa
          Length = 168

 Score = 59.3 bits (142), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 31/65 (47%), Positives = 40/65 (61%)

Query: 7   IGGAQIYAEALPLADRLIITRIAQTFDCDAFFPALDQQVWQETAREEHHSETSGLDYAFV 66
           IGGAQ+YAEALP A RL +TR+    + DAFFP +D   W+  +  EH +      YAF 
Sbjct: 104 IGGAQLYAEALPRAARLYLTRVGLAPEGDAFFPEIDGAAWRLASSIEHAAADDAPAYAFE 163

Query: 67  TYERR 71
            +ERR
Sbjct: 164 VWERR 168