BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0021.p (562 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0292 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 903 0.0 XF2397 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, c... 736 0.0 NMB1400 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 696 0.0 NMA1620 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 694 0.0 alr1614 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 553 e-157 >RSp0292 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Rso Ralstonia solanacearum Length = 725 Score = 903 bits (2333), Expect = 0.0, Method: Compositional matrix adjust. Identities = 431/553 (77%), Positives = 494/553 (89%) Query: 1 LLISLMLQLIALCTPLFFQVVMDKVLVNHAMKTLNVIAVGLVAATLFEAILGGIRTALFA 60 LL+SL LQ+I L TP+FFQVVMDKVLVNHAMKTLNVIAVGL+ A LFE L IRT +FA Sbjct: 173 LLVSLTLQIIGLVTPMFFQVVMDKVLVNHAMKTLNVIAVGLICAILFEVTLTSIRTWVFA 232 Query: 61 HTSSKIDVELGSRLFSHLLSLPISYFQARRAGDSVARIRELENIRSFLTSNAMTLVLDIV 120 HTSSKIDVELG+RLF HLLSLP++YFQ+RR GDSVAR+RELENIRSFLT NAMT+VLD++ Sbjct: 233 HTSSKIDVELGARLFRHLLSLPLAYFQSRRVGDSVARVRELENIRSFLTGNAMTVVLDLL 292 Query: 121 FSFVFLGVMLWYSVTLSLVVLASIPLYLALSFVFTPVLRRRLDDKFNKGAENQAFLVETL 180 FSFVFL VMLWYSV L+L+V+ SIPLY+ LS VFTP++R RLD KFN+ AENQ+FLVET+ Sbjct: 293 FSFVFLAVMLWYSVWLTLIVVVSIPLYIGLSAVFTPIIRARLDVKFNRNAENQSFLVETI 352 Query: 181 TGMDTVKAMAVEPRWQQKWDRQLAAYVAASLSTTNIGLMASGGVSLISKLATAAIMWLGA 240 +G+DTVKAMAVEPRW KWD+QLAAYV A L+ TN+ +ASGGV+L+SKL TAAIMWLGA Sbjct: 353 SGIDTVKAMAVEPRWTHKWDQQLAAYVTAGLAVTNVATVASGGVTLVSKLVTAAIMWLGA 412 Query: 241 TLVIDNQLTVGELIAFNMLAGQVSSPILRLAQLWNDFQQVGISMSRLGDVLDTRPEIDGK 300 TLVID+++TVGEL+AFNMLAGQVSSPILRLAQLWNDFQQVGISMSRLGD+L+ R E+ G+ Sbjct: 413 TLVIDHKMTVGELVAFNMLAGQVSSPILRLAQLWNDFQQVGISMSRLGDILNARTEVAGQ 472 Query: 301 KTRLPRLTGAIDFDQVFFRYRPEASDVIRSLSLQVRPGEVIGIVGRSGSGKSTLTKLVQR 360 K+RLP+L GAI FDQV FRYRP+A DVIR +SL + PGEVIGIVGRSGSGKSTLTKLVQR Sbjct: 473 KSRLPKLAGAIAFDQVAFRYRPDAPDVIRGISLAIAPGEVIGIVGRSGSGKSTLTKLVQR 532 Query: 361 LHVCDRGRVMVDGQDIAIIDTASLRQQIGVVLQENMLFSRSIRDNIALSDPSMPIEKIIA 420 L+V +RGRV++DGQDIAI+DT SLRQQIGVVLQEN LFSRSIRDNIAL++P+ P+E II Sbjct: 533 LYVPERGRVLIDGQDIAIVDTTSLRQQIGVVLQENTLFSRSIRDNIALTNPAAPLEAIIE 592 Query: 421 VAKLAGAHEFICELPEAYDTLVGEHGTGLSGGQRQRIAIARVLITNPGILIFDEATSALD 480 A+LAGAHEFICELPE YDT+VGEHGTGLSGGQRQRIAIAR L+TNP ILIFDEATSALD Sbjct: 593 AARLAGAHEFICELPEGYDTIVGEHGTGLSGGQRQRIAIARALLTNPRILIFDEATSALD 652 Query: 481 YESEKIIQDNMRQICAGRTVLIIAHRLSAVRDAHRIIVMDKGQIVESGSHDELLKQARGL 540 YESEKIIQDNMR+IC GRTVLIIAHRLSAVR+A+RIIVM++GQI E GSHD+LLK +G+ Sbjct: 653 YESEKIIQDNMRRICQGRTVLIIAHRLSAVREANRIIVMERGQIAEMGSHDQLLKHPQGI 712 Query: 541 YAHLYGLQTAQGA 553 YAHLY LQ A Sbjct: 713 YAHLYALQQGGAA 725 >XF2397 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Xfa Xylella fastidiosa 9a5c Length = 720 Score = 736 bits (1900), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/546 (63%), Positives = 441/546 (80%) Query: 3 ISLMLQLIALCTPLFFQVVMDKVLVNHAMKTLNVIAVGLVAATLFEAILGGIRTALFAHT 62 +SL +Q+ AL TPLF+QVVMDKVLV+ A+ TL VI VGL++ LFE +L +RT +FAHT Sbjct: 171 VSLFIQIFALVTPLFYQVVMDKVLVHQALSTLEVIVVGLISLALFEVLLTTLRTHVFAHT 230 Query: 63 SSKIDVELGSRLFSHLLSLPISYFQARRAGDSVARIRELENIRSFLTSNAMTLVLDIVFS 122 +SKIDVELG+RLF HLL+LP++YF++RR GD++AR+RELENIR FLT A+T VLD++F+ Sbjct: 231 TSKIDVELGARLFRHLLALPLAYFESRRVGDTIARVRELENIRHFLTGQALTSVLDLLFT 290 Query: 123 FVFLGVMLWYSVTLSLVVLASIPLYLALSFVFTPVLRRRLDDKFNKGAENQAFLVETLTG 182 VFL VM WYS L+L+V+ S+PLY +S TPVLR+RLD+KF +GA+NQAFLVET++G Sbjct: 291 VVFLSVMFWYSSWLTLIVVISLPLYALISAFITPVLRKRLDEKFARGADNQAFLVETVSG 350 Query: 183 MDTVKAMAVEPRWQQKWDRQLAAYVAASLSTTNIGLMASGGVSLISKLATAAIMWLGATL 242 + TVKAMAV+PR + WD QLA YV AS S T I + V L+ KL A+++ GA L Sbjct: 351 IGTVKAMAVDPRVTRTWDNQLAGYVGASFSVTKIATLGQQSVQLVQKLTNVAVLFWGAKL 410 Query: 243 VIDNQLTVGELIAFNMLAGQVSSPILRLAQLWNDFQQVGISMSRLGDVLDTRPEIDGKKT 302 VID QL++G+LIAFNML+GQV++PI+RLAQLW DFQQVG+S+ RLG++L+TR E+ G + Sbjct: 411 VIDGQLSLGQLIAFNMLSGQVTAPIIRLAQLWQDFQQVGLSVERLGEILNTRTELPGSRM 470 Query: 303 RLPRLTGAIDFDQVFFRYRPEASDVIRSLSLQVRPGEVIGIVGRSGSGKSTLTKLVQRLH 362 LP + G I F+++ FRYRP+ DV+ + L ++PGEVIGIVGRSGSGKSTLTKLVQR++ Sbjct: 471 TLPPIQGRITFERLIFRYRPDTPDVLAGIDLDIQPGEVIGIVGRSGSGKSTLTKLVQRMY 530 Query: 363 VCDRGRVMVDGQDIAIIDTASLRQQIGVVLQENMLFSRSIRDNIALSDPSMPIEKIIAVA 422 V +RGRV+VD D+++ D A LR+QIGVVLQEN LF+RS+R+NIA++DP +P+E++I A Sbjct: 531 VPERGRVLVDSHDLSLADPAWLRRQIGVVLQENFLFNRSVRENIAMADPGIPLERVIHAA 590 Query: 423 KLAGAHEFICELPEAYDTLVGEHGTGLSGGQRQRIAIARVLITNPGILIFDEATSALDYE 482 LAGAH FI ELPE YDT +GEHGTGLSGGQRQRIAIAR LI +P ILIFDEATSALDYE Sbjct: 591 TLAGAHPFIAELPEGYDTKIGEHGTGLSGGQRQRIAIARALIGDPRILIFDEATSALDYE 650 Query: 483 SEKIIQDNMRQICAGRTVLIIAHRLSAVRDAHRIIVMDKGQIVESGSHDELLKQARGLYA 542 SE + NMR IC GRTVLIIAHRLS VR+A RI+V+DKG+IVESGSH+ LL + G YA Sbjct: 651 SEHAVMQNMRAICKGRTVLIIAHRLSTVRNADRIVVIDKGKIVESGSHETLLNRNNGHYA 710 Query: 543 HLYGLQ 548 HLY LQ Sbjct: 711 HLYRLQ 716 >NMB1400 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Nme Neisseria meningitidis MC58 Length = 742 Score = 696 bits (1795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/540 (63%), Positives = 429/540 (79%) Query: 10 IALCTPLFFQVVMDKVLVNHAMKTLNVIAVGLVAATLFEAILGGIRTALFAHTSSKIDVE 69 AL TPLFFQVVMDKVLV+ TL+V++V L+ +LFE +LGG+RT LFAHT+S+IDVE Sbjct: 202 FALITPLFFQVVMDKVLVHRGFSTLDVVSVALLVVSLFEIVLGGLRTYLFAHTTSRIDVE 261 Query: 70 LGSRLFSHLLSLPISYFQARRAGDSVARIRELENIRSFLTSNAMTLVLDIVFSFVFLGVM 129 LG+RLF HLLSLP+SYF+ RR GD+VAR+RELE IR+FLT A+T VLD+ FSF+FL VM Sbjct: 262 LGARLFRHLLSLPLSYFEHRRVGDTVARVRELEQIRNFLTGQALTSVLDLAFSFIFLAVM 321 Query: 130 LWYSVTLSLVVLASIPLYLALSFVFTPVLRRRLDDKFNKGAENQAFLVETLTGMDTVKAM 189 +YS TL+ VVLAS+P Y S +P+LR RL+DKF + A+NQ+FLVE++T + TVKAM Sbjct: 322 WYYSSTLTWVVLASLPAYAFWSAFISPILRTRLNDKFARNADNQSFLVESITAVGTVKAM 381 Query: 190 AVEPRWQQKWDRQLAAYVAASLSTTNIGLMASGGVSLISKLATAAIMWLGATLVIDNQLT 249 AVEP+ Q+WD QLAAYVA+ T + ++ GV LI KL T A +W+GA LVI+++LT Sbjct: 382 AVEPQMTQRWDNQLAAYVASGFRVTKLAVVGQQGVQLIQKLVTVATLWIGARLVIESKLT 441 Query: 250 VGELIAFNMLAGQVSSPILRLAQLWNDFQQVGISMSRLGDVLDTRPEIDGKKTRLPRLTG 309 VG+LIAFNML+GQV++P++RLAQLW DFQQVGIS++RLGD+L+ E LP + G Sbjct: 442 VGQLIAFNMLSGQVAAPVIRLAQLWQDFQQVGISVARLGDILNAPTENASSHLALPDIRG 501 Query: 310 AIDFDQVFFRYRPEASDVIRSLSLQVRPGEVIGIVGRSGSGKSTLTKLVQRLHVCDRGRV 369 I F+ V FRY+ + +++ L+L++R GEV+GIVGRSGSGKSTLTKLVQRL+V ++GRV Sbjct: 502 EITFEHVDFRYKADGRLILQDLNLRIRAGEVLGIVGRSGSGKSTLTKLVQRLYVPEQGRV 561 Query: 370 MVDGQDIAIIDTASLRQQIGVVLQENMLFSRSIRDNIALSDPSMPIEKIIAVAKLAGAHE 429 +VDG D+A+ A LR+Q+GVVLQEN+L +RSIRDNIAL+D MP+E+II AKLAGAHE Sbjct: 562 LVDGNDLALAAPAWLRRQVGVVLQENVLLNRSIRDNIALTDTGMPLERIIEAAKLAGAHE 621 Query: 430 FICELPEAYDTLVGEHGTGLSGGQRQRIAIARVLITNPGILIFDEATSALDYESEKIIQD 489 FI ELPE Y T+VGE G GLSGGQRQRIAIAR LITNP ILIFDEATSALDYESE+ I Sbjct: 622 FIMELPEGYGTVVGEQGAGLSGGQRQRIAIARALITNPRILIFDEATSALDYESERAIMQ 681 Query: 490 NMRQICAGRTVLIIAHRLSAVRDAHRIIVMDKGQIVESGSHDELLKQARGLYAHLYGLQT 549 NM+ ICA RTVLIIAHRLS V+ AHRII MDKG+IVE+G+ ELL + G Y +LY LQ Sbjct: 682 NMQAICANRTVLIIAHRLSTVKTAHRIIAMDKGRIVEAGTQQELLAKPNGYYRYLYDLQN 741 >NMA1620 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain NmA Neisseria meningitidis Z2491 Length = 742 Score = 694 bits (1791), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/540 (63%), Positives = 428/540 (79%) Query: 10 IALCTPLFFQVVMDKVLVNHAMKTLNVIAVGLVAATLFEAILGGIRTALFAHTSSKIDVE 69 AL TPLFFQVVMDKVLV+ TL+V++V L+ +LFE +LGG+RT LFAHT+S+IDVE Sbjct: 202 FALITPLFFQVVMDKVLVHRGFSTLDVVSVALLVVSLFEIVLGGLRTYLFAHTTSRIDVE 261 Query: 70 LGSRLFSHLLSLPISYFQARRAGDSVARIRELENIRSFLTSNAMTLVLDIVFSFVFLGVM 129 LG+RLF HLLSLP+SYF+ RR GD+VAR+RELE IR+FLT A+T VLD+ FSF+FL VM Sbjct: 262 LGARLFRHLLSLPLSYFEHRRVGDTVARVRELEQIRNFLTGQALTSVLDLAFSFIFLAVM 321 Query: 130 LWYSVTLSLVVLASIPLYLALSFVFTPVLRRRLDDKFNKGAENQAFLVETLTGMDTVKAM 189 +YS TL+ VVLAS+P Y S +P+LR RL+DKF + A+NQ+FLVE++T + TVKAM Sbjct: 322 WYYSSTLTWVVLASLPAYAFWSAFISPILRTRLNDKFARNADNQSFLVESITAVGTVKAM 381 Query: 190 AVEPRWQQKWDRQLAAYVAASLSTTNIGLMASGGVSLISKLATAAIMWLGATLVIDNQLT 249 AVEP+ Q+WD QLAAYVA+ T + ++ GV LI KL T A +W+GA LVI+++LT Sbjct: 382 AVEPQMTQRWDNQLAAYVASGFRVTKLAVVGQQGVQLIQKLVTVATLWIGARLVIESKLT 441 Query: 250 VGELIAFNMLAGQVSSPILRLAQLWNDFQQVGISMSRLGDVLDTRPEIDGKKTRLPRLTG 309 VG+LIAFNML+GQV++P++RLAQLW DFQQVGIS++RLGD+L+ E LP + G Sbjct: 442 VGQLIAFNMLSGQVAAPVIRLAQLWQDFQQVGISVARLGDILNAPTENASSHLALPDIRG 501 Query: 310 AIDFDQVFFRYRPEASDVIRSLSLQVRPGEVIGIVGRSGSGKSTLTKLVQRLHVCDRGRV 369 I F+ V FRY+ + +++ L+L++R GEV+GIVGRSGSGKSTLTKLVQRL+V +GRV Sbjct: 502 EITFEHVDFRYKADGRLILQDLNLRIRAGEVLGIVGRSGSGKSTLTKLVQRLYVPAQGRV 561 Query: 370 MVDGQDIAIIDTASLRQQIGVVLQENMLFSRSIRDNIALSDPSMPIEKIIAVAKLAGAHE 429 +VDG D+A+ A LR+Q+GVVLQEN+L +RSIRDNIAL+D MP+E+II AKLAGAHE Sbjct: 562 LVDGNDLALAAPAWLRRQVGVVLQENVLLNRSIRDNIALTDTGMPLERIIEAAKLAGAHE 621 Query: 430 FICELPEAYDTLVGEHGTGLSGGQRQRIAIARVLITNPGILIFDEATSALDYESEKIIQD 489 FI ELPE Y T+VGE G GLSGGQRQRIAIAR LITNP ILIFDEATSALDYESE+ I Sbjct: 622 FIMELPEGYGTVVGEQGAGLSGGQRQRIAIARALITNPRILIFDEATSALDYESERAIMQ 681 Query: 490 NMRQICAGRTVLIIAHRLSAVRDAHRIIVMDKGQIVESGSHDELLKQARGLYAHLYGLQT 549 NM+ ICA RTVLIIAHRLS V+ AHRII MDKG+IVE+G+ ELL + G Y +LY LQ Sbjct: 682 NMQAICANRTVLIIAHRLSTVKTAHRIIAMDKGRIVEAGTQQELLAKPNGYYRYLYDLQN 741 >alr1614 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Nos Nostoc sp. PCC 7120 Length = 893 Score = 553 bits (1424), Expect = e-157, Method: Compositional matrix adjust. Identities = 266/551 (48%), Positives = 394/551 (71%), Gaps = 2/551 (0%) Query: 1 LLISLMLQLIALCTPLFFQVVMDKVLVNHAMKTLNVIAVGLVAATLFEAILGGIRTALFA 60 LL S LQL+ L TPL QVV+DKV+V ++ TL+V+A+ L+ +FE+ILG +R +F Sbjct: 342 LLASFTLQLLGLGTPLITQVVIDKVMVQESLPTLDVMAIALLLIAVFESILGILRLFIFT 401 Query: 61 HTSSKIDVELGSRLFSHLLSLPISYFQARRAGDSVARIRELENIRSFLTSNAMTLVLDIV 120 HT+ ++D+ L ++LF HL+ LP++YF++RR GD+VAR++ELE IR FLT A+T++LD + Sbjct: 402 HTARRLDLSLSAQLFRHLMRLPLAYFESRRVGDTVARVQELEQIRQFLTGTALTVILDSI 461 Query: 121 FSFVFLGVMLWYSVTLSLVVLASIPLYLALSFVFTPVLRRRLDDKFNKGAENQAFLVETL 180 F+ V+L +M +Y++ L+ V LA +PL+ L+ V TP+LR L++ FN+ A++Q+FLVET+ Sbjct: 462 FAVVYLALMFYYNIPLTFVALAVLPLFATLTIVATPILRNWLNETFNRSADSQSFLVETV 521 Query: 181 TGMDTVKAMAVEPRWQQKWDRQLAAYVAASLSTTNIGLMASGGVSLISKLATAAIMWLGA 240 TG+ +VKA A E + +W+ A +V + ++S ++ ++ I+W GA Sbjct: 522 TGIHSVKAHAAESVARDRWEGLFARFVRTGFKASTTSNISSNIGDFLTNFSSLLILWFGA 581 Query: 241 TLVIDNQLTVGELIAFNMLAGQVSSPILRLAQLWNDFQQVGISMSRLGDVLDTRPEID-G 299 LVID +LT+G+L+AF ML+G+V+ P+LRL QLW + QQV +S+ R+GD+L+ PE + G Sbjct: 582 KLVIDQKLTIGQLVAFQMLSGRVTGPLLRLVQLWQNLQQVLLSVDRIGDILNVAPEAEMG 641 Query: 300 KKTRLPRLTGAIDFDQVFFRYRPEASDVIRSLSLQVRPGEVIGIVGRSGSGKSTLTKLVQ 359 LP L G + F+Q+FFRY+ V+R +S V PG+ +GIVGRSGSGKSTL+KL+Q Sbjct: 642 TGLVLPPLKGQVSFEQIFFRYKTNTEPVLRGISFNVEPGQFVGIVGRSGSGKSTLSKLLQ 701 Query: 360 RLHVCDRGRVMVDGQDIAIIDTASLRQQIGVVLQENMLFSRSIRDNIALSDPSMPIEKII 419 RL+ + GR+++DG DI D +SLRQQIGVVLQE+ LF+ SI +NI L +P + E+++ Sbjct: 702 RLYQIESGRILIDGFDIKSADLSSLRQQIGVVLQEDFLFNGSILENITLGNPDITAEQVV 761 Query: 420 AVAKLAGAHEFICELPEAYDTLVGEHGTGLSGGQRQRIAIARVLITNPGILIFDEATSAL 479 A+LA AH+FI +LP Y+T VGE GT LSGGQRQRIA+AR+ +++ IL+ DEATSAL Sbjct: 762 EAARLAVAHDFISQLPYGYETNVGERGTALSGGQRQRIALARLFLSDSPILVLDEATSAL 821 Query: 480 DYESEKIIQDNMRQICAGRTVLIIAHRLSAVRDAHRIIVMDKGQIVESGSHDELLKQARG 539 D E+E+ + N+++I A RTV +IAHR + ++ A I+V++KG I E G+H ELL+Q +G Sbjct: 822 DSETEQQVLQNLQKISANRTVFLIAHRFAPLKRADLILVLEKGVIAERGTHPELLQQ-KG 880 Query: 540 LYAHLYGLQTA 550 LY LY Q A Sbjct: 881 LYWSLYQRQQA 891