BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0009.p (587 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5529 [P] COG0475 Kef-type K+ transport systems, membrane compo... 769 0.0 alr2046_1 [P] COG0475 Kef-type K+ transport systems, membrane co... 201 3e-51 STM0492_1 [P] COG4651 Kef-type K+ transport system, predicted NA... 192 1e-48 YPO3094_1 [P] COG4651 Kef-type K+ transport system, predicted NA... 190 1e-47 ybaL_1 [P] COG4651 Kef-type K+ transport system, predicted NAD-b... 189 1e-47 >PA5529 [P] COG0475 Kef-type K+ transport systems, membrane components Pae Pseudomonas aeruginosa Length = 585 Score = 769 bits (1985), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/582 (66%), Positives = 485/582 (83%), Gaps = 1/582 (0%) Query: 1 MHEVELFIQDMAIIMLIAGIVTVVFNKLKQPVVLGYIVAGVIIGPHTPPYDLIQDEKTVH 60 MH V+ FIQD+A+IML+AG+VT++F++L+QPVVLGYIVAG IIGPHTPP+ LI DE T+ Sbjct: 1 MHAVD-FIQDLAVIMLVAGVVTILFHRLRQPVVLGYIVAGFIIGPHTPPFGLIHDEDTIK 59 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAFIGAAAEILLMIWIGYEIGLYFGWKRMDAI 120 L+ELGVIFL+F LGLEFSL+KL +VGATAFI A EI+LMIWIG+EIG +F W MD++ Sbjct: 60 TLAELGVIFLMFCLGLEFSLRKLFQVGATAFIAAFLEIVLMIWIGFEIGRFFEWSTMDSL 119 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIALLSGVATSGSVD 180 FLGA+LA+SSTTIIVKAL +L MKNE+FAQ+IFG+LIVEDIL IG+IALLSG+A SGSV+ Sbjct: 120 FLGAILAISSTTIIVKALGDLKMKNERFAQLIFGVLIVEDILGIGIIALLSGIAVSGSVE 179 Query: 181 STEVFTTVGKLVLFMTVSLVVGILAVPRLLSFISRFKSNEMLLVAVLGVLFGFCLLVMKL 240 + EVF+TVGKL LFM V+LVVGIL VPRLL+++++F+SNEMLLV VLG+ FGFCLLV+KL Sbjct: 180 TGEVFSTVGKLSLFMIVALVVGILLVPRLLAYVAKFESNEMLLVTVLGLCFGFCLLVVKL 239 Query: 241 QYSVALGAFLVGAVMAESRHLHRIERLVEPIRDMFSAIFFVAIGLLFDPNVLVKYWMPIT 300 +YS+ LGAFL+GA+MAESR L +IERL+EP+RDMFSAIFFVAIGLL DP +LV+Y PI Sbjct: 240 EYSMVLGAFLIGAIMAESRQLVQIERLIEPVRDMFSAIFFVAIGLLIDPKILVEYAWPIA 299 Query: 301 VITLAVVFGKLISCGLGTFIAGQGGRTPMRVGMGLAQIGEFSFIIAALGQSLKVTSDFLY 360 +IT+AVV GK+ SCG+G FIAG GRT +RVGMGL+QIGEFSFIIAALG +LKVTSDFLY Sbjct: 300 LITVAVVLGKMFSCGMGAFIAGNDGRTSLRVGMGLSQIGEFSFIIAALGMTLKVTSDFLY 359 Query: 361 PIVVAVSAVTALLTPYLIKAADPLSAKAVTLVPARVSGLMGMYSRWLESLQPTGDRAELT 420 P+ VAVSA+T LLTPYLI+AADPLS +P R++ + G Y WL S+QP GDRA L Sbjct: 360 PVAVAVSAITTLLTPYLIRAADPLSQHLANAMPQRMARIFGHYGDWLRSIQPQGDRAVLA 419 Query: 421 RIIRRILMQVMVNLALVIAIFLGGAFFVDGLSRQLSGWTPDPDVQKAIIWGCALVLSLPF 480 +IRRIL+QV VNLALVIAIFL G +F D LS +S W + KA+IWG AL++SL F Sbjct: 420 AMIRRILLQVGVNLALVIAIFLAGGYFADTLSAWMSQWVAYDGLHKALIWGGALLVSLAF 479 Query: 481 LIATYRKLQALSMLLAEVSVKPEFAGAYTSGVRKIVSEVLPIMSIVGIMLLIFVLSASIL 540 LIA YRKL+ALSMLLAE+ VKPE AG +T+ VR+++SE++P++S+ G+M+L+ LS+SIL Sbjct: 480 LIAAYRKLKALSMLLAELGVKPEKAGRHTARVRRVISEIIPLLSLAGMMVLLAALSSSIL 539 Query: 541 PPLNLLAFVLAGAAGLLWLLWSKLVKLHSRLQIALFETLDEQ 582 PP LL V+ A ++ +LW L+++HSR+QIAL ETLD++ Sbjct: 540 PPGELLVVVVLVAGLVIAVLWRWLIRVHSRMQIALMETLDQE 581 >alr2046_1 [P] COG0475 Kef-type K+ transport systems, membrane components Nos Nostoc sp. PCC 7120 Length = 399 Score = 201 bits (512), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 138/389 (35%), Positives = 226/389 (58%), Gaps = 19/389 (4%) Query: 1 MHEVELFIQDMAIIMLIAGIVTVVFNKLKQPVVLGYIVAGVIIGPHTPPYDLIQDEKTVH 60 M E I D+ ++ +A + LKQPV+LGY++ G+++GP LI++ V Sbjct: 1 MQEDFRLIVDLVSVLAVAACGGLFAALLKQPVLLGYLIGGMVVGPAG--LGLIKEVIQVE 58 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAFIGAAAEILLMIWIGYEI-GLYFGWKRMDA 119 L++ GV FLLF+LG+EFS +L KV A A G +I L I + GL W + A Sbjct: 59 TLAQFGVAFLLFALGVEFSFAELKKVKAIALGGGGLQIALTILTTVLVCGLTGAWGALPA 118 Query: 120 --IFLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIG-MIALLSGVATS 176 +FLG++L++SST +++K L E Q++ GIL+V+D LA+G M+A+L + Sbjct: 119 KGVFLGSILSLSSTAVVLKCLMERNETETPHGQVMLGILVVQD-LALGLMLAVLPALHEP 177 Query: 177 GSVDSTEVFTTVGKLVLFMTVSLVVGILAVPRLLSFISRFKSNEMLLVAVLGVLFGFCLL 236 G V V T + ++ LF ++ GI +P LL ++R +S E+ L+ V+ + G LL Sbjct: 178 GEVIVVAVLTALVRIGLFAAGAVAAGIWVIPPLLRLLARTESRELFLLGVVALCLGIALL 237 Query: 237 VMKLQYSVALGAFLVGAVMAESRHLHRIERLVEPIRDMFSAIFFVAIGLLFDPNVLVKYW 296 L S+ +GAF+ G +++E + + VEP+RD+F+++FF AIG+L DP L++ Sbjct: 238 TESLGLSIEMGAFVAGLMISEVEYADQTLTYVEPLRDIFASLFFAAIGMLIDPVFLLQNI 297 Query: 297 MPITVITLAVVFGK--LISCGLGTFIAGQGGRTPMRV----GMGLAQIGEFSFIIAALGQ 350 I + V GK +I+ + F R P++ G+GLAQIGEFSF++A+ GQ Sbjct: 298 ELILGLVALVFLGKFLIITPLVKLF------RYPLKTALIAGLGLAQIGEFSFVLASEGQ 351 Query: 351 SLKVTSDFLYPIVVAVSAVTALLTPYLIK 379 +L + S +Y +++ +AVT +LTP++++ Sbjct: 352 ALGLVSRRVYLLILGTTAVTLMLTPFVLR 380 >STM0492_1 [P] COG4651 Kef-type K+ transport system, predicted NAD-binding component Sty Salmonella typhimurium LT2 Length = 412 Score = 192 bits (489), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 133/395 (33%), Positives = 218/395 (55%), Gaps = 10/395 (2%) Query: 1 MHEVELFIQDMAIIMLIAGIVTVVFNKLKQPVVLGYIVAGVIIGPHTPPYDLIQDEKTVH 60 MH I + +++A I+ ++ NKL+ ++GY++AGV+ GP TP + + D K Sbjct: 1 MHHATPLITTIVGGLVLAFILGMIANKLRISPLVGYLLAGVLAGPFTPGF--VADTKLAP 58 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAFIGAAAEILLMIWIGYEIGLYFGWKRMDAI 120 L+ELGVI L+F +GL FSLK L V + A GA A+I + +G + GW M I Sbjct: 59 ELAELGVILLMFGVGLHFSLKDLMAVKSIAIPGAVAQIAVATLLGMALSAVLGWSLMTGI 118 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIAL---LSGVATSG 177 G L+ +ST ++++AL E + + + QI G LIVED++ + + L ++G+ G Sbjct: 119 VFGLCLSTASTVVLLRALEERQLLDSQRGQIAIGWLIVEDLVMVLTLVLLPAVAGMVEKG 178 Query: 178 SVD----STEVFTTVGKLVLFMTVSLVVGILAVPRLLSFISRFKSNEMLLVAVLGVLFGF 233 V + ++ T+GK+V F+ + ++VG VP +++ + S E+ ++VL + G Sbjct: 179 DVGIASLTVDMGITIGKVVAFIAIMMLVGRRLVPWIMARSAATGSRELFTLSVLALALGI 238 Query: 234 CLLVMKL-QYSVALGAFLVGAVMAESRHLHRIERLVEPIRDMFSAIFFVAIGLLFDPNVL 292 ++L S ALGAF G V+ ES HR P+RD F+ +FFV++G+LFDP VL Sbjct: 239 AFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLPLRDAFAVLFFVSVGMLFDPLVL 298 Query: 293 VKYWMPITVITLAVVFGKLISCGLGTFIAGQGGRTPMRVGMGLAQIGEFSFIIAALGQSL 352 ++ + + +VFGK I+ + G RT + + LAQIGEF+FI+A LG +L Sbjct: 299 IQQPLAVLATLAIIVFGKSIAAFFLVRLFGHSPRTALTIAASLAQIGEFAFILAGLGMAL 358 Query: 353 KVTSDFLYPIVVAVSAVTALLTPYLIKAADPLSAK 387 + +V+A + ++ +L P L + AK Sbjct: 359 NLLPQAGQNLVLAGAILSIMLNPVLFTLLEKYLAK 393 >YPO3094_1 [P] COG4651 Kef-type K+ transport system, predicted NAD-binding component Ype Yersinia pestis Length = 396 Score = 190 bits (482), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 132/398 (33%), Positives = 218/398 (54%), Gaps = 10/398 (2%) Query: 1 MHEVELFIQDMAIIMLIAGIVTVVFNKLKQPVVLGYIVAGVIIGPHTPPYDLIQDEKTVH 60 MH I + +++A + + ++L+ ++GY+ AGV+ GP TP + + D Sbjct: 1 MHHSTPLITTIVGGLVLAFLFGTLAHRLRISPLVGYLAAGVLAGPFTPGF--VADTSLAP 58 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAFIGAAAEILLMIWIGYEIGLYFGWKRMDAI 120 L+E+GVI L+F +GL FSLK L V + A GA A+I + +G + + GW + + Sbjct: 59 ELAEIGVILLMFGVGLHFSLKDLLAVKSIAIPGAIAQIAVATLLGMGLSHFLGWDLITGL 118 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVED---ILAIGMIALLSGVATSG 177 G L+ +ST ++++AL E + + + QI G LIVED +L + ++ +GV + Sbjct: 119 VFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLAMVLTLVLLPAFAGVMGNE 178 Query: 178 SVDSTEVFT----TVGKLVLFMTVSLVVGILAVPRLLSFISRFKSNEMLLVAVLGVLFGF 233 + + ++FT T+GK++ F+T+ +VVG VP +L+ + S E+ +AVL + G Sbjct: 179 TTNLNQLFTELAITIGKVIAFITLMIVVGRRLVPWILAKTASTGSRELFTLAVLVLALGI 238 Query: 234 CLLVMKL-QYSVALGAFLVGAVMAESRHLHRIERLVEPIRDMFSAIFFVAIGLLFDPNVL 292 ++L S ALGAF G V+ ES HR + P+RD F+ +FFV++G+LFDP +L Sbjct: 239 AYGAVELFDVSFALGAFFAGMVLNESELSHRAAQDTLPLRDAFAVLFFVSVGMLFDPMIL 298 Query: 293 VKYWMPITVITLAVVFGKLISCGLGTFIAGQGGRTPMRVGMGLAQIGEFSFIIAALGQSL 352 V + + ++FGK + G RT + + + LAQIGEF+FI+A LG SL Sbjct: 299 VNEPLAVIASLAIIIFGKSAIAFALVRLFGHSKRTALTISVSLAQIGEFAFILAGLGISL 358 Query: 353 KVTSDFLYPIVVAVSAVTALLTPYLIKAADPLSAKAVT 390 + S +V+A + ++ +L P L D AK T Sbjct: 359 GLLSGHGRNLVLASAILSIMLNPLLFTLLDRYLAKTET 396 >ybaL_1 [P] COG4651 Kef-type K+ transport system, predicted NAD-binding component Eco Escherichia coli K12 Length = 409 Score = 189 bits (481), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 135/397 (34%), Positives = 223/397 (56%), Gaps = 14/397 (3%) Query: 1 MHEVELFIQDMAIIMLIAGIVTVVFNKLKQPVVLGYIVAGVIIGPHTPPYDLIQDEKTVH 60 MH I + +++A I+ ++ NKL+ ++GY++AGV+ GP TP + + D K Sbjct: 1 MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAGPFTPGF--VADTKLAP 58 Query: 61 ILSELGVIFLLFSLGLEFSLKKLAKVGATAFIGAAAEILLMIWIGYEIGLYFGWKRMDAI 120 L+ELGVI L+F +GL FSLK L V A A GA A+I + +G + GW M I Sbjct: 59 ELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLLGMALSAVLGWSLMTGI 118 Query: 121 FLGAMLAVSSTTIIVKALNELGMKNEKFAQIIFGILIVEDILAIGMIAL---LSGVATSG 177 G L+ +ST ++++AL E + + + QI G LIVED++ + + L ++G+ G Sbjct: 119 VFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLVMVLTLVLLPAVAGMMEQG 178 Query: 178 SVD----STEVFTTVGKLVLFMTVSLVVGILAVPRLLSFISRFKSNEMLLVAVLGVLFGF 233 V + ++ T+GK++ F+ + ++VG VP +++ + S E+ ++VL + G Sbjct: 179 DVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARSAATGSRELFTLSVLALALGV 238 Query: 234 CLLVMKL-QYSVALGAFLVGAVMAESRHLHRIERLVEPIRDMFSAIFFVAIGLLFDPNVL 292 ++L S ALGAF G V+ ES HR P+RD F+ +FFV++G+LFDP +L Sbjct: 239 AFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLPLRDAFAVLFFVSVGMLFDPLIL 298 Query: 293 VKYWMPITVI-TLAVV-FGKLISCGLGTFIAGQGGRTPMRVGMGLAQIGEFSFIIAALGQ 350 ++ P+ V+ TLA++ FGK ++ + G RT + + LAQIGEF+FI+A LG Sbjct: 299 IQQ--PLAVLATLAIILFGKSLAAFFLVRLFGHSQRTALTIAASLAQIGEFAFILAGLGM 356 Query: 351 SLKVTSDFLYPIVVAVSAVTALLTPYLIKAADPLSAK 387 +L + +V+A + ++ +L P L + AK Sbjct: 357 ALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLAK 393