BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0069.p (475 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1712 [GEPR] COG0477 Permeases of the major facilitator superf... 454 e-127 Z2875 [GEPR] COG0477 Permeases of the major facilitator superfam... 441 e-123 ECs2538 [GEPR] COG0477 Permeases of the major facilitator superf... 441 e-123 yebQ [GEPR] COG0477 Permeases of the major facilitator superfami... 441 e-123 STM1843 [GEPR] COG0477 Permeases of the major facilitator superf... 427 e-119 >YPO1712 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 454 bits (1167), Expect = e-127, Method: Compositional matrix adjust. Identities = 232/448 (51%), Positives = 317/448 (70%), Gaps = 2/448 (0%) Query: 22 EGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLQTTPAASVWIVTAYQLAMMV 81 +GLP QR AIL + + + +A LD IAN ALP +A DL T+PA S+W+V AYQLA+ + Sbjct: 7 DGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITI 66 Query: 82 ALLPLAALGEIIGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMSVNT 141 +LL +A+LG+IIGYRR+Y GL++F+ SL CA++ SL TL AR LQG G A +MSVNT Sbjct: 67 SLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNT 126 Query: 142 ALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVLAVVL 201 ALIR IYP LGRG+G+NTLIVA++ GPS+A+ +L++A W WLFA+NVP+G+LA L Sbjct: 127 ALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIGLLAWCL 186 Query: 202 AVPSLP--HTSLARHAFDLRSALLNAAAFGLLILAIGEGAHQTQASVVGLELAAAILCGL 259 + LP +T + FD+ S +LNA FGLLI AI + +V+ ++ A +L G Sbjct: 187 GIKFLPANNTKSNGNRFDITSCVLNALTFGLLITAISGFSQGQSPAVIAAQVVALLLIGF 246 Query: 260 FLLKRELSHPAPMLPVDLFRHPMFSLSAVTAVCSFAAQGLAFVSLPFFFHHDLGRSQVEI 319 F ++R+L+ P+LPVDL R P+F+LS T++ SFAAQ LA VSLPFF LGR +V Sbjct: 247 FFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVAT 306 Query: 320 GLLMTPWPVAVAIMAPIAGRMSDRYPVGMLGGVGLALLCAGLLSMTFMPASPSVWEISWR 379 GLL+TPWP+A ++APIAGR+ +RY G+LGG+GLA+ +GL + +PA+PS +I WR Sbjct: 307 GLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSDVDIIWR 366 Query: 380 MLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLSQTQ 439 M+LCG GFG FQ+PN ++++AP HRSGGASG++ TARLLGQ+ GAALVAL FN+ T Sbjct: 367 MILCGAGFGLFQTPNNHTIISAAPQHRSGGASGMLGTARLLGQTSGAALVALMFNMFSTN 426 Query: 440 GSRLALGFGAAFAGAACIASFLRLLTRN 467 G+ +L FA A + S LR+ ++ Sbjct: 427 GTHASLILAGCFASIAALVSLLRVTQKS 454 >Z2875 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 494 Score = 441 bits (1135), Expect = e-123, Method: Compositional matrix adjust. Identities = 227/429 (52%), Positives = 307/429 (71%), Gaps = 2/429 (0%) Query: 19 IAGEGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLQTTPAASVWIVTAYQLA 78 + +GLP QR AIL + I + +A LD AIAN ALP +A DL TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVALLPLAALGEIIGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMS 138 ++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMS 160 Query: 139 VNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVLA 198 VNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NVPLG++A Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 VVLAVPSLP--HTSLARHAFDLRSALLNAAAFGLLILAIGEGAHQTQASVVGLELAAAIL 256 ++LA+ LP + ++ FDL SA++NA FGLLI A+ A +++ EL ++ Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGLFLLKRELSHPAPMLPVDLFRHPMFSLSAVTAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G+F ++R+LS P P+LPVDL R P+FSLS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRMSDRYPVGMLGGVGLALLCAGLLSMTFMPASPSVWEI 376 VE GLL+TPWP+A +MAP+AG + +R G+LG +GL ++ AGL S+ +PASP+ I Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINI 400 Query: 377 SWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLS 436 W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 401 IWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQF 460 Query: 437 QTQGSRLAL 445 G+ ++L Sbjct: 461 GDNGTHVSL 469 >ECs2538 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 494 Score = 441 bits (1135), Expect = e-123, Method: Compositional matrix adjust. Identities = 227/429 (52%), Positives = 307/429 (71%), Gaps = 2/429 (0%) Query: 19 IAGEGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLQTTPAASVWIVTAYQLA 78 + +GLP QR AIL + I + +A LD AIAN ALP +A DL TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVALLPLAALGEIIGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMS 138 ++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMS 160 Query: 139 VNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVLA 198 VNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NVPLG++A Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 VVLAVPSLP--HTSLARHAFDLRSALLNAAAFGLLILAIGEGAHQTQASVVGLELAAAIL 256 ++LA+ LP + ++ FDL SA++NA FGLLI A+ A +++ EL ++ Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGLFLLKRELSHPAPMLPVDLFRHPMFSLSAVTAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G+F ++R+LS P P+LPVDL R P+FSLS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRMSDRYPVGMLGGVGLALLCAGLLSMTFMPASPSVWEI 376 VE GLL+TPWP+A +MAP+AG + +R G+LG +GL ++ AGL S+ +PASP+ I Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINI 400 Query: 377 SWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLS 436 W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 401 IWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQF 460 Query: 437 QTQGSRLAL 445 G+ ++L Sbjct: 461 GDNGTHVSL 469 >yebQ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 494 Score = 441 bits (1134), Expect = e-123, Method: Compositional matrix adjust. Identities = 227/429 (52%), Positives = 307/429 (71%), Gaps = 2/429 (0%) Query: 19 IAGEGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLQTTPAASVWIVTAYQLA 78 + +GLP QR AIL + I + +A LD AIAN ALP +A DL TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVALLPLAALGEIIGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMS 138 ++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMS 160 Query: 139 VNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVLA 198 VNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NVPLG++A Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 VVLAVPSLP--HTSLARHAFDLRSALLNAAAFGLLILAIGEGAHQTQASVVGLELAAAIL 256 ++LA+ LP + ++ FDL SA++NA FGLLI A+ A +++ EL ++ Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGLFLLKRELSHPAPMLPVDLFRHPMFSLSAVTAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G+F ++R+LS P P+LPVDL R P+FSLS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRMSDRYPVGMLGGVGLALLCAGLLSMTFMPASPSVWEI 376 VE GLL+TPWP+A +MAP+AG + +R G+LG +GL ++ AGL S+ +PASP+ I Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINI 400 Query: 377 SWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLS 436 W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 401 IWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQF 460 Query: 437 QTQGSRLAL 445 G+ ++L Sbjct: 461 GDNGTHVSL 469 >STM1843 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 457 Score = 427 bits (1099), Expect = e-119, Method: Compositional matrix adjust. Identities = 234/446 (52%), Positives = 313/446 (70%), Gaps = 6/446 (1%) Query: 22 EGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLQTTPAASVWIVTAYQLAMMV 81 +GLP QR AIL + I + +A LD AIAN ALP +A DL +PA+S+WIV AYQ+A++V Sbjct: 7 DGLPLPQRYGAILTIIIGISMAVLDGAIANVALPTIATDLHASPASSIWIVNAYQIAIVV 66 Query: 82 ALLPLAALGEIIGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMSVNT 141 +LL L+ LG++ GY RIY GLV+F +SL CA++ SL L +AR QG GGA +MSVNT Sbjct: 67 SLLSLSFLGDMFGYHRIYKCGLVVFLLSSLFCALSDSLQMLTLARIAQGFGGAALMSVNT 126 Query: 142 ALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVLAVVL 201 ALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+I+ W WLF +NVPLG++A++L Sbjct: 127 ALIRLIYPQRHLGRGMGINSFIVAVSSAAGPTIAAAILSISSWKWLFLINVPLGIIALIL 186 Query: 202 AVPSLP----HTSLARHAFDLRSALLNAAAFGLLILAIGEGAHQTQASVVGLELAAAILC 257 A+ LP H + R FDL SA++NA FGLLI A+ A +++G EL ++ Sbjct: 187 AIRFLPANIAHDTKPR--FDLPSAVMNALTFGLLITALSGFAQGQSLTLIGAELLVLVVV 244 Query: 258 GLFLLKRELSHPAPMLPVDLFRHPMFSLSAVTAVCSFAAQGLAFVSLPFFFHHDLGRSQV 317 G F ++R+LS P P+LP+DL R P+FSLS T++CSF AQ LA VSLPF+ LGRS+V Sbjct: 245 GFFFVRRQLSLPVPLLPIDLLRIPLFSLSIGTSICSFCAQMLAMVSLPFYLQTVLGRSEV 304 Query: 318 EIGLLMTPWPVAVAIMAPIAGRMSDRYPVGMLGGVGLALLCAGLLSMTFMPASPSVWEIS 377 E GLL+TPWP+A +MAP+AG + +R G+LG +G+ ++ AGL ++ +PASPS I Sbjct: 305 ETGLLLTPWPLATMVMAPLAGYLIERLHAGLLGALGMVIMAAGLFALVMLPASPSDLNII 364 Query: 378 WRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLSQ 437 W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 365 WPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSTGAALVALMLNQFG 424 Query: 438 TQGSRLALGFGAAFAGAACIASFLRL 463 G+ L+L A A A + S LR+ Sbjct: 425 DSGTHLSLLAAAILAILAAVVSGLRI 450