BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0061.p (740 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1953 [GER] COG0697 Permeases of the drug/metabolite transport... 162 3e-39 BH0390 [GER] COG0697 Permeases of the drug/metabolite transporte... 125 5e-28 BS_yetK [GER] COG0697 Permeases of the drug/metabolite transport... 103 2e-21 SMc00428 [GER] COG0697 Permeases of the drug/metabolite transpor... 72 3e-12 RSp0685 [GER] COG0697 Permeases of the drug/metabolite transport... 70 1e-11 >RSc1953 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 336 Score = 162 bits (410), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 101/246 (41%), Positives = 148/246 (60%), Gaps = 4/246 (1%) Query: 14 LILSMSLVGAYVALTKPLAAMLPVFLLAWLRFGIGAVAMLRWLKKPASEQPLSTQSRWL- 72 LI +M+LVG+ V K + A++PV L A LRF I M W + S T+ W Sbjct: 25 LIAAMALVGSNVGFGKSIVAVMPVMLFALLRFVIAVACMAPWYRP--SRMRRVTRGEWTN 82 Query: 73 VFLESFLGNFLFTLCMITGVSMTNAVSAGVIMSAIPAVVAVMSWIFLKEKISLRVWGAVA 132 +FL++ G F FTL M+ GV +T+A++AG+I S IPA VA++SW+ L+EK S R +V Sbjct: 83 LFLQALFGTFGFTLLMLNGVRLTSALAAGIITSTIPATVALLSWLVLREKPSGRTLVSVT 142 Query: 133 CGAVGIGLLSLAKDG-HGASAASGGQYAWLGNGLVFCAVLCEAAYAAIGKKLTAVLTPKR 191 G+ LL+ + G +A + A LGN LV AVLCE+ Y + ++LT L Sbjct: 143 LAVAGVALLNADRGGEFAGAAPADAARALLGNALVMGAVLCESVYVVLSRRLTQTLPAIE 202 Query: 192 ISAVINLWGLLLMTPMGVYTALHFDFGAVPANMWLLLLFYGLAASVWTVWLWMTGLKVVP 251 I A +L G LLM P+G+ L FD +VP ++W L+++Y L+AS+++ WLWM G++ VP Sbjct: 203 ICAYTHLIGALLMLPLGLAPLLTFDLSSVPPHIWGLVVWYALSASLFSFWLWMKGIRHVP 262 Query: 252 AARAGL 257 A AG+ Sbjct: 263 AHLAGV 268 >BH0390 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bha Bacillus halodurans Length = 311 Score = 125 bits (313), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 84/245 (34%), Positives = 139/245 (56%), Gaps = 5/245 (2%) Query: 14 LILSMSLVGAYVALTKPLAAMLPVFLLAWLRFGIGAVAMLRWLKKPASEQPLSTQSRWLV 73 ++ +M +VG+ V K L PVFL + LRF I A+ ++ L K S + ++ Sbjct: 11 IMFAMVIVGSSVVAGKMLVESFPVFLASELRFLIAALILVPMLLKKEGIPTFSKKEVGIL 70 Query: 74 FLESFLGNFLFTLCMITGVSMTNAVSAGVIMSAIPAVVAVMSWIFLKEKIS-LRVWGAVA 132 FL++ G FLF++ M+ G+ T A+ G+IMS +PAVVA+M++I LKEK++ L + G + Sbjct: 71 FLQALSGVFLFSIFMLYGLMYTTAMEGGIIMSTLPAVVALMAFITLKEKLTRLTIIGILL 130 Query: 133 CGAVGIGLLSLAKDGHGASAASGGQYAWLGNGLVFCAVLCEAAYAAIGKKLTAVLTPKRI 192 AVG G L++ G S G LGN L+ AV+ EA + GK ++ ++P I Sbjct: 131 --AVG-GTLAINTSGT-LSDVERGVAPLLGNLLIIGAVISEALFIIFGKSISQRVSPLAI 186 Query: 193 SAVINLWGLLLMTPMGVYTALHFDFGAVPANMWLLLLFYGLAASVWTVWLWMTGLKVVPA 252 S +++++G++L P +Y A F V N WL++ ++G+ +V L G++ VPA Sbjct: 187 STMVSVFGVVLFLPFAIYEATRFPLTDVSLNDWLIIFYFGVVVTVIAFVLMYQGIEKVPA 246 Query: 253 ARAGL 257 + G+ Sbjct: 247 STVGV 251 >BS_yetK [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 330 Score = 103 bits (256), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 80/261 (30%), Positives = 140/261 (53%), Gaps = 14/261 (5%) Query: 7 RPMG-YGCLILSMSLVGAYVALTKPLAAMLPVFLLAWLRFGIGAVAMLRWLKKPASEQP- 64 + MG Y L +M++VG+ V + K + +PVFL + LRF I +V +L L P Sbjct: 25 KQMGAYVSLAAAMAIVGSSVVVGKLMVERIPVFLSSGLRFLIASVVLLMLLFCIEKGFPA 84 Query: 65 LSTQSRWLVFLESFLGNFLFTLCMITGVSMTNAVSAGVIMSAIPAVVAVMSWIFLKEKIS 124 L+ + +++ ++SF G FLF++C++ GV T +G++ S P ++ ++S+ L+EKI Sbjct: 85 LTKKDVFVLLVQSFTGVFLFSICLLYGVQYTTGTESGILTSTTPMLIGILSFFLLREKIE 144 Query: 125 LRVWGAV---ACGAVGIGLLSLAKDGHGASAASGGQYAWLGNGLVFCAVLCEAAYAAIGK 181 + + CG + I L GA + G +A GN L+ AV+ EA + + K Sbjct: 145 KKTLIGILLAVCGVMAINL-------FGAGSQDGTPHALFGNMLIIAAVIGEALFTLMAK 197 Query: 182 KLTAVLTPKRISAVINLWGLLLMTPMGVYTALHFDFGAVPANM-WLLLLFYGLAASVWTV 240 L+ ++ IS ++L+G L P ++ A FD+ +VP + W +L+Y L +V Sbjct: 198 LLSPHISALAISTFVSLFGFLFFLPFALFEASSFDY-SVPTVLDWSYVLYYALFVTVLAF 256 Query: 241 WLWMTGLKVVPAARAGLRHRI 261 +LW +G+ VPA +G+ + Sbjct: 257 YLWYSGVTKVPAGVSGIFTSV 277 >SMc00428 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 298 Score = 72.4 bits (176), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 66/214 (30%), Positives = 106/214 (49%), Gaps = 16/214 (7%) Query: 10 GYGCLILSMSLVGAYVALTKPLAAMLPVFLLAWLRFGIGAVAMLRWLKKPASEQPLSTQS 69 GY L L+M LVG+ V +K +AA LP F LRF I L ++ + P +S Sbjct: 7 GYVFLSLAMVLVGSTVIASKIIAAGLPPFTATALRFAIAFPLFLGLMRATGASWPKLPKS 66 Query: 70 RWLVFL-ESFLGNFLFTLCMITGVSMTNAVSAGVIMSAIPAVVAVMSWIFLKEKISLRVW 128 WLV L ++ G+ +T +I+G+ +T+A AGVI+ +P V A ++ + L E+ V Sbjct: 67 DWLVLLFQAGAGSVGYTTLLISGLKLTSAADAGVIIGTLPVVSAAIAIMVLGERPHRSVL 126 Query: 129 GAVACGAVGIGLLSLAKDGHGASAASGGQYAWLGNGLVFCAVLCEAAYAAIGKKLTAVLT 188 A A G+ + D + A ++ G+ L+F AV+CE + + K+++ + Sbjct: 127 AAACLAAAGVLAIVFRPDANAA-------HSLAGSALIFGAVICEGLFILLNKRVSVAIP 179 Query: 189 PKRISAVINLWGLLLMTPMGVYTALHFDFGAVPA 222 P +SA LMT G AL F +P+ Sbjct: 180 PLGLSA--------LMTGFGGAIALPFALAELPS 205 >RSp0685 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 300 Score = 70.5 bits (171), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 72/248 (29%), Positives = 123/248 (49%), Gaps = 25/248 (10%) Query: 6 SRPMGYGCLILSMSLVGAYVALTKPLAAMLPVFLLAWLRFGIG-----AVAMLRWLKKPA 60 +R +GY L L+M VG+ V +K +A LP F LRF + A+ +LR + P Sbjct: 3 NRTIGYLLLSLAMMTVGSTVIASKLIAGNLPPFPATALRFAVALPFLFALVLLRGQRWPR 62 Query: 61 SEQPLSTQSRWLVFLESFLGNFLFTLCMITGVSMTNAVSAGVIMSAIPAVVAVMSWIFLK 120 LS ++ L+ L++ G+ +T +I+G++ A AGV++ +PAV A+ S I L Sbjct: 63 ----LSGRAWGLLVLQAGAGSVGYTTLLISGLAHLPAADAGVVIGTLPAVSALFSVIVLG 118 Query: 121 EKISLRVWGAVACGAVGIGLLSLAKDGHGASAASGGQYAWLGNGLVFCAVLCEAAYAAIG 180 E+ LR+ +V +G+ +++A G G++ +G + + AV+CE+A+ + Sbjct: 119 ERPKLRLMVSVLLATIGV--MAVAWTGSGSAPLTGVLF-------ILGAVVCESAFILLN 169 Query: 181 KKLTAVLTPKRISAVINLWGLLLMTPMGV--YTALHFDFGAVPANMWLLLLFYGLAASVW 238 K++ L P + + GLL+ P V + A A+ A +W Y L +V Sbjct: 170 KRMPVPLPPLLQATAMTALGLLVSLPFAVLEFPATVPSTAAIAAVVW-----YALVPTVG 224 Query: 239 TVWLWMTG 246 LW G Sbjct: 225 GFLLWYAG 232