BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0040.p (327 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0322 [H] COG0320 Lipoate synthase Rso Ralstonia solanacearum 366 e-101 NMA1378 [H] COG0320 Lipoate synthase NmA Neisseria meningitidis ... 311 2e-84 NMB1216 [H] COG0320 Lipoate synthase Nme Neisseria meningitidis ... 310 2e-84 PA3996 [H] COG0320 Lipoate synthase Pae Pseudomonas aeruginosa 284 2e-76 lipA [H] COG0320 Lipoate synthase Eco Escherichia coli K12 276 7e-74 >RSc0322 [H] COG0320 Lipoate synthase Rso Ralstonia solanacearum Length = 333 Score = 366 bits (939), Expect = e-101, Method: Compositional matrix adjust. Identities = 176/234 (75%), Positives = 195/234 (83%), Gaps = 8/234 (3%) Query: 10 DSSSNATGSARA-----NPLD---KQKGAGKTAWIPIKVVAAEKLKKPDWIRVKAGSPTT 61 DS+S A+ A P D KQK KTA IPIK+V AEKLKKP+WIRVKA + + Sbjct: 3 DSASGASAVANIATPSNEPYDATRKQKSLDKTARIPIKIVPAEKLKKPEWIRVKAATGNS 62 Query: 62 RFYEIKDILRANNLVTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDP 121 RFYEIKDILRANNLVTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDP Sbjct: 63 RFYEIKDILRANNLVTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDP 122 Query: 122 LDPNEPENLAKTIAQLRLSYVVITSVDRDDLRDGGAAHFAACIQRVRELSPETRIEILTP 181 LD NEPENLAKTIAQLRL+YVVITSVDRDDLRDGGA H+ CI R RELSP TRIE+L P Sbjct: 123 LDANEPENLAKTIAQLRLNYVVITSVDRDDLRDGGAQHYVDCISRTRELSPATRIEVLVP 182 Query: 182 DFRGRMDRALEILKMAPPDVMNHNLETAPRLYKEARPGSDYEYSLSLLKRLLSR 235 DFRGR+++AL+IL+ PPDVMNHN+ET PRLYK+ARPG+DY +SL LLK +R Sbjct: 183 DFRGRLEKALDILQACPPDVMNHNMETVPRLYKQARPGADYAHSLKLLKDFKAR 236 >NMA1378 [H] COG0320 Lipoate synthase NmA Neisseria meningitidis Z2491 Length = 327 Score = 311 bits (796), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 148/207 (71%), Positives = 172/207 (83%), Gaps = 3/207 (1%) Query: 26 KQKGAGKTAWIPIKVV-AAEKLKKPDWIRVKAGSPTTRFYEIKDILRANNLVTVCEEASC 84 K +GA KTA IPIKVV EKLKKP+WIR K P+ +F+EIKDILR + TVCEEASC Sbjct: 14 KLRGADKTARIPIKVVPLQEKLKKPEWIRAKL--PSRKFFEIKDILREQKMHTVCEEASC 71 Query: 85 PNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDPNEPENLAKTIAQLRLSYVVI 144 PNIGECF KGTATFMIMGD CTRRCPFCDVGHGRP+ LDP+EP+NLA+++ + L YVVI Sbjct: 72 PNIGECFSKGTATFMIMGDICTRRCPFCDVGHGRPNMLDPDEPKNLAESVKAMNLRYVVI 131 Query: 145 TSVDRDDLRDGGAAHFAACIQRVRELSPETRIEILTPDFRGRMDRALEILKMAPPDVMNH 204 TSVDRDDLRDGGA HFA CI+ +RE SP T+IEIL PDFRGR+D AL+IL PPDVMNH Sbjct: 132 TSVDRDDLRDGGAQHFADCIKAIRETSPNTKIEILVPDFRGRLDIALKILAETPPDVMNH 191 Query: 205 NLETAPRLYKEARPGSDYEYSLSLLKR 231 NLET P LY++ARPG++Y++SL LLKR Sbjct: 192 NLETHPSLYRKARPGANYQHSLDLLKR 218 >NMB1216 [H] COG0320 Lipoate synthase Nme Neisseria meningitidis MC58 Length = 327 Score = 310 bits (795), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 148/207 (71%), Positives = 171/207 (82%), Gaps = 3/207 (1%) Query: 26 KQKGAGKTAWIPIKVV-AAEKLKKPDWIRVKAGSPTTRFYEIKDILRANNLVTVCEEASC 84 K +GA KTA IPIKVV EKLKKP+WIR K P+ +F+EIKDILR + TVCEEASC Sbjct: 14 KLRGADKTARIPIKVVPLQEKLKKPEWIRAKL--PSRKFFEIKDILREQKMHTVCEEASC 71 Query: 85 PNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDPNEPENLAKTIAQLRLSYVVI 144 PNIGECF KGTATFMIMGD CTRRCPFCDVGHGRP+ LDP+EP NLA+++ + L YVVI Sbjct: 72 PNIGECFSKGTATFMIMGDICTRRCPFCDVGHGRPNMLDPDEPRNLAESVKAMNLRYVVI 131 Query: 145 TSVDRDDLRDGGAAHFAACIQRVRELSPETRIEILTPDFRGRMDRALEILKMAPPDVMNH 204 TSVDRDDLRDGGA HFA CI+ +RE SP T+IEIL PDFRGR+D AL+IL PPDVMNH Sbjct: 132 TSVDRDDLRDGGAQHFADCIKAIRETSPNTKIEILVPDFRGRLDIALKILAETPPDVMNH 191 Query: 205 NLETAPRLYKEARPGSDYEYSLSLLKR 231 NLET P LY++ARPG++Y++SL LLKR Sbjct: 192 NLETHPSLYRKARPGANYQHSLDLLKR 218 >PA3996 [H] COG0320 Lipoate synthase Pae Pseudomonas aeruginosa Length = 327 Score = 284 bits (726), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 138/209 (66%), Positives = 162/209 (77%), Gaps = 4/209 (1%) Query: 26 KQKGAGKTAWIPIKVVAAEKL-KKPDWIRVKA-GSPTTRFYEIKDILRANNLVTVCEEAS 83 K +GA K A IP+K++ E+L KKPDWIRV+ SP IK +LR + L +VCEEAS Sbjct: 21 KLRGAEKVARIPVKIIPTEELPKKPDWIRVRIPVSPEVD--RIKQLLRKHKLHSVCEEAS 78 Query: 84 CPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDPNEPENLAKTIAQLRLSYVV 143 CPN+GECF GTATFMIMGD CTRRCPFCDVGHGRP PLD +EP NLA IA LRL YVV Sbjct: 79 CPNLGECFSGGTATFMIMGDICTRRCPFCDVGHGRPKPLDVDEPTNLAIAIADLRLKYVV 138 Query: 144 ITSVDRDDLRDGGAAHFAACIQRVRELSPETRIEILTPDFRGRMDRALEILKMAPPDVMN 203 ITSVDRDDLRDGGA HFA C++ +R+LSP ++E L PD+RGRMD ALEI PPDV N Sbjct: 139 ITSVDRDDLRDGGAQHFADCLREIRKLSPGIQLETLVPDYRGRMDIALEITANEPPDVFN 198 Query: 204 HNLETAPRLYKEARPGSDYEYSLSLLKRL 232 HNLET PRLY+ +RPGSD+E+SL LL++ Sbjct: 199 HNLETVPRLYRSSRPGSDFEWSLDLLQKF 227 >lipA [H] COG0320 Lipoate synthase Eco Escherichia coli K12 Length = 321 Score = 276 bits (705), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 130/210 (61%), Positives = 156/210 (74%), Gaps = 3/210 (1%) Query: 26 KQKGAGKTAWIPIKVVAAEK---LKKPDWIRVKAGSPTTRFYEIKDILRANNLVTVCEEA 82 K + A K A IP+K VA E+ L+KP+W+++K + +TR IK +R N L +VCEEA Sbjct: 12 KYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEA 71 Query: 83 SCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDPNEPENLAKTIAQLRLSYV 142 SCPN+ ECF GTATFMI+G CTRRCPFCDV HGRP D NEP LA+TIA + L YV Sbjct: 72 SCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLAQTIADMALRYV 131 Query: 143 VITSVDRDDLRDGGAAHFAACIQRVRELSPETRIEILTPDFRGRMDRALEILKMAPPDVM 202 VITSVDRDDLRDGGA HFA CI +RE SP+ +IE L PDFRGRMDRAL+IL PPDV Sbjct: 132 VITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVF 191 Query: 203 NHNLETAPRLYKEARPGSDYEYSLSLLKRL 232 NHNLE PR+Y++ RPG+DY +SL LL+R Sbjct: 192 NHNLENVPRIYRQVRPGADYNWSLKLLERF 221