BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0022.p (518 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3328 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved... 836 0.0 NMA0074 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved... 706 0.0 NMB0193 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved... 706 0.0 ZgidA [D] COG0445 NAD/FAD-utilizing enzyme apparently involved i... 699 0.0 ECs4683 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved... 699 0.0 >RSc3328 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division Rso Ralstonia solanacearum Length = 647 Score = 836 bits (2159), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/513 (77%), Positives = 456/513 (88%), Gaps = 7/513 (1%) Query: 1 VDDLMLEGDRVVGAVTQAGIRFAGRAVVLTAGTFLDGKIHVGLNNYSGGRAGDPPAVSLS 60 V+DL++EGDRVVGAVTQ G+RF RAVVLTAGTFLDGKIHVGLNNY+GGRAGDP AVSLS Sbjct: 125 VEDLLVEGDRVVGAVTQVGVRFRARAVVLTAGTFLDGKIHVGLNNYTGGRAGDPAAVSLS 184 Query: 61 ARLKELKLPQGRLKTGTPPRIDGRSINLAILEEQPGDLDPVPVFSVMGNAAMHPRQMPCW 120 ARLKELKLPQGRLKTGTPPRIDGR+I+ ++LE QPGDLDPVPVFS +G MHPRQ+PCW Sbjct: 185 ARLKELKLPQGRLKTGTPPRIDGRTIDFSVLEAQPGDLDPVPVFSFLGRTDMHPRQVPCW 244 Query: 121 ITHTNSRTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIYLEPEGLT 180 +THTN RTHDIIR GL+RSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQI+LEPEGLT Sbjct: 245 VTHTNERTHDIIRAGLNRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEPEGLT 304 Query: 181 THEFYPNGISTSLPFDVQLELVRSMKGMENAHILRPGYAIEYDYYDPRGLKSSLETRQVQ 240 T+EFYPNG+STSLPFDVQL+L+ SM+G+E+AHILRPGYAIEYDY+DPRGLK+SLE++ + Sbjct: 305 TNEFYPNGVSTSLPFDVQLDLIHSMRGLEHAHILRPGYAIEYDYFDPRGLKASLESKAIG 364 Query: 241 GLFFAGQINGTTGYEEAAAQGMLAGINAALQTQGREAWTPRRDEAYLGVLVDDLVTQGVQ 300 GLFFAGQINGTTGYEEAAAQG+LAGINA LQ QG+ AWTPRRD+AYLGVLVDDL+T+GV Sbjct: 365 GLFFAGQINGTTGYEEAAAQGLLAGINAGLQVQGKAAWTPRRDQAYLGVLVDDLITRGVT 424 Query: 301 EPYRMFTSRAEYRLSLREDNADLRLTEIGRELGCVGDAQWEAFDRKREAVSREMERLKST 360 EPYRMFTSRAE+RLSLREDNAD+RLTE GR+LG V DA+W+AF+RKR+AVSRE ERLKST Sbjct: 425 EPYRMFTSRAEFRLSLREDNADMRLTEAGRDLGVVDDARWDAFNRKRDAVSRETERLKST 484 Query: 361 WVNPRILAAAEAERVLGKAIEREYNLLDLLRRPNVSYDSLMGLTGTEGQALAGPGIEDGP 420 WVNP IL AA+AE VLGK IEREY+L DLLRRPNV+Y+SLMG+ G G+ + D P Sbjct: 485 WVNPAILPAADAEPVLGKGIEREYSLADLLRRPNVTYESLMGMQG--GKYAPDAPLADEP 542 Query: 421 -----VREQVEIQVKYAGYIARQANEISRQDHNENLKLPADLDYMDVKALSIEVRQKLNK 475 +REQ+EI +KY GYIARQA+E+ R NEN +LPAD DY V+ LSIEV+QKL + Sbjct: 543 LLAEQIREQIEIGIKYHGYIARQADEVERLGANENTRLPADFDYKQVRGLSIEVQQKLAQ 602 Query: 476 HRPETLGQASRISGVTPAALSLLLVHLKKGGLK 508 H+PET+GQASRISG+TPAA+SLLLVHLKKG L+ Sbjct: 603 HKPETIGQASRISGITPAAVSLLLVHLKKGVLR 635 >NMA0074 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division NmA Neisseria meningitidis Z2491 Length = 628 Score = 706 bits (1823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/505 (69%), Positives = 411/505 (81%), Gaps = 6/505 (1%) Query: 1 VDDLMLEGDRVVGAVTQAGIRFAGRAVVLTAGTFLDGKIHVGLNNYSGGRAGDPPAVSLS 60 V+D+ L+G+R+ G +T G+ F RAVVLTAGTFL GKIH+GL NY GGRAGDP A SL Sbjct: 125 VEDVTLDGERISGVITAMGVEFKARAVVLTAGTFLSGKIHIGLENYEGGRAGDPAAKSLG 184 Query: 61 ARLKELKLPQGRLKTGTPPRIDGRSINLAILEEQPGDLDPVPVFSVMGNAAMHPRQMPCW 120 RL+ELKLPQGRLKTGTPPRIDGR+I+ + L EQPGD PVPV SV GNA MHPRQ+ CW Sbjct: 185 GRLRELKLPQGRLKTGTPPRIDGRTIDFSQLTEQPGD-TPVPVMSVRGNAEMHPRQVSCW 243 Query: 121 ITHTNSRTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIYLEPEGLT 180 ITHTN++THDIIR G DRSPM+TG IEGVGPRYCPSIEDKI+RFA KDSHQI+LEPEGLT Sbjct: 244 ITHTNTQTHDIIRSGFDRSPMFTGKIEGVGPRYCPSIEDKINRFADKDSHQIFLEPEGLT 303 Query: 181 THEFYPNGISTSLPFDVQLELVRSMKGMENAHILRPGYAIEYDYYDPRGLKSSLETRQVQ 240 T+E+YPNGISTSLPFD+Q+ LVRSMKG+ENAHILRPGYAIEYDY+DPR LK+SLET+ ++ Sbjct: 304 TYEYYPNGISTSLPFDIQIALVRSMKGLENAHILRPGYAIEYDYFDPRNLKASLETKTIE 363 Query: 241 GLFFAGQINGTTGYEEAAAQGMLAGINAALQTQGREAWTPRRDEAYLGVLVDDLVTQGVQ 300 GLFFAGQINGTTGYEEAAAQG+LAG NA +G++ RR++AYLGVLVDDL+T+GV Sbjct: 364 GLFFAGQINGTTGYEEAAAQGLLAGANAVQYVRGQDPLLLRREQAYLGVLVDDLITKGVN 423 Query: 301 EPYRMFTSRAEYRLSLREDNADLRLTEIGRELGCVGDAQWEAFDRKREAVSREMERLKST 360 EPYRMFTSRAEYRL LREDNAD+RLTE G ++G VG+AQW F+ KREAV RE++RLK+T Sbjct: 424 EPYRMFTSRAEYRLQLREDNADMRLTEDGYKIGLVGEAQWRMFNEKREAVEREIQRLKTT 483 Query: 361 WVNPRILAAAEAERVLGKAIEREYNLLDLLRRPNVSYDSLMGLTGTEGQALAGPGIEDGP 420 W P+ LA E RV G+ + RE NL DLLRRPN+ Y +LM L G A+ + Sbjct: 484 WYTPQKLAEDEQIRVFGQKLSREANLHDLLRRPNLDYAALMTLEG----AMPSENL-SAE 538 Query: 421 VREQVEIQVKYAGYIARQANEISRQDHNENLKLPADLDYMDVKALSIEVRQKLNKHRPET 480 V EQVEIQVKY GYI RQ EI + E LKLP +DY VK LS EV+QKLN+H+PET Sbjct: 539 VIEQVEIQVKYQGYIDRQNEEIDSRRDIETLKLPDGIDYGKVKGLSAEVQQKLNQHKPET 598 Query: 481 LGQASRISGVTPAALSLLLVHLKKG 505 +GQASRISGVTPAA++LL+VHLK+G Sbjct: 599 VGQASRISGVTPAAVALLMVHLKRG 623 >NMB0193 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division Nme Neisseria meningitidis MC58 Length = 631 Score = 706 bits (1822), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/505 (69%), Positives = 409/505 (80%), Gaps = 6/505 (1%) Query: 1 VDDLMLEGDRVVGAVTQAGIRFAGRAVVLTAGTFLDGKIHVGLNNYSGGRAGDPPAVSLS 60 V+D+ L+G+R+ G +T G+ F RAVVLTAGTFL GKIH+GL NY GGRAGDP A SL Sbjct: 128 VEDVTLDGERISGVITAMGVEFKARAVVLTAGTFLSGKIHIGLENYEGGRAGDPAAKSLG 187 Query: 61 ARLKELKLPQGRLKTGTPPRIDGRSINLAILEEQPGDLDPVPVFSVMGNAAMHPRQMPCW 120 RL+ELKLPQGRLKTGTPPRIDGR+I+ + L EQPGD PVPV SV GNA MHPRQ+ CW Sbjct: 188 GRLRELKLPQGRLKTGTPPRIDGRTIDFSQLTEQPGD-TPVPVMSVRGNADMHPRQVSCW 246 Query: 121 ITHTNSRTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIYLEPEGLT 180 ITHTN++THDIIR G DRSPM+TG IEGVGPRYCPSIEDKI+RFA KDSHQI+LEPEGLT Sbjct: 247 ITHTNTQTHDIIRSGFDRSPMFTGKIEGVGPRYCPSIEDKINRFADKDSHQIFLEPEGLT 306 Query: 181 THEFYPNGISTSLPFDVQLELVRSMKGMENAHILRPGYAIEYDYYDPRGLKSSLETRQVQ 240 THE+YPNGISTSLPFD+Q+ LVRSMKG+ENAHILRPGYAIEYDY+DPR LK+SLET+ + Sbjct: 307 THEYYPNGISTSLPFDIQIALVRSMKGLENAHILRPGYAIEYDYFDPRNLKASLETKTIA 366 Query: 241 GLFFAGQINGTTGYEEAAAQGMLAGINAALQTQGREAWTPRRDEAYLGVLVDDLVTQGVQ 300 GLFFAGQINGTTGYEEAAAQG+LAG NA +G++ RR++AYLGVLVDDL+T+GV Sbjct: 367 GLFFAGQINGTTGYEEAAAQGLLAGANAVQYVRGQDPLLLRREQAYLGVLVDDLITKGVN 426 Query: 301 EPYRMFTSRAEYRLSLREDNADLRLTEIGRELGCVGDAQWEAFDRKREAVSREMERLKST 360 EPYRMFTSRAEYRL LREDNAD+RLTE G ++G V +AQW F+ KREAV RE++RLK+T Sbjct: 427 EPYRMFTSRAEYRLQLREDNADMRLTEDGYKIGLVSEAQWRMFNEKREAVEREIQRLKTT 486 Query: 361 WVNPRILAAAEAERVLGKAIEREYNLLDLLRRPNVSYDSLMGLTGTEGQALAGPGIEDGP 420 W P+ LA E RV G+ + RE NL DLLRRPN+ Y +LM L G A+ + Sbjct: 487 WYTPQKLAEGEQIRVFGQKLSREANLHDLLRRPNLDYAALMTLEG----AMPSENL-SAE 541 Query: 421 VREQVEIQVKYAGYIARQANEISRQDHNENLKLPADLDYMDVKALSIEVRQKLNKHRPET 480 V EQVEIQVKY GYI RQ EI + E LKLP +DY VK LS EV+QKLN+H+PET Sbjct: 542 VIEQVEIQVKYQGYIDRQNEEIDSRRDIETLKLPDGIDYGKVKGLSAEVQQKLNQHKPET 601 Query: 481 LGQASRISGVTPAALSLLLVHLKKG 505 +GQASRISGVTPAA++LL+VHLK+G Sbjct: 602 VGQASRISGVTPAAVALLMVHLKRG 626 >ZgidA [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division EcZ Escherichia coli O157:H7 EDL933 Length = 629 Score = 699 bits (1804), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/507 (66%), Positives = 403/507 (79%), Gaps = 7/507 (1%) Query: 1 VDDLMLEGDRVVGAVTQAGIRFAGRAVVLTAGTFLDGKIHVGLNNYSGGRAGDPPAVSLS 60 V+DL++E DRVVGAVTQ G++F +AVVLT GTFLDGKIH+GL+NYSGGRAGDPP++ LS Sbjct: 125 VEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLS 184 Query: 61 ARLKELKLPQGRLKTGTPPRIDGRSINLAILEEQPGDLDPVPVFSVMGNAAMHPRQMPCW 120 RL+EL L GRLKTGTPPRID R+I+ ++L +Q GD +P+PVFS MGNA+ HP+Q+PC+ Sbjct: 185 RRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGD-NPMPVFSFMGNASQHPQQVPCY 243 Query: 121 ITHTNSRTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIYLEPEGLT 180 ITHTN +THD+IR LDRSPMY GVIEGVGPRYCPSIEDK+ RFA ++ HQI+LEPEGLT Sbjct: 244 ITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLT 303 Query: 181 THEFYPNGISTSLPFDVQLELVRSMKGMENAHILRPGYAIEYDYYDPRGLKSSLETRQVQ 240 ++E YPNGISTSLPFDVQ+++VRSM+GMENA I+RPGYAIEYD++DPR LK +LE++ +Q Sbjct: 304 SNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQ 363 Query: 241 GLFFAGQINGTTGYEEAAAQGMLAGINAALQTQGREAWTPRRDEAYLGVLVDDLVTQGVQ 300 GLFFAGQINGTTGYEEAAAQG+LAG+NAA + +E W P R +AYLGVLVDDL T G + Sbjct: 364 GLFFAGQINGTTGYEEAAAQGLLAGLNAARLSDDKEGWAPARSQAYLGVLVDDLCTLGTK 423 Query: 301 EPYRMFTSRAEYRLSLREDNADLRLTEIGRELGCVGDAQWEAFDRKREAVSREMERLKST 360 EPYRMFTSRAEYRL LREDNADLRLTEIGRELG V D +W F+ K E + RE +RLKST Sbjct: 424 EPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKST 483 Query: 361 WVNPRILAAAEAERVLGKAIEREYNLLDLLRRPNVSYDSLMGLTGTEGQALAGPGIEDGP 420 WV P AAAE L + RE + DLLRRP ++Y+ L LT P + D Sbjct: 484 WVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPF------APALTDEQ 537 Query: 421 VREQVEIQVKYAGYIARQANEISRQDHNENLKLPADLDYMDVKALSIEVRQKLNKHRPET 480 EQVEIQVKY GYIARQ +EI +Q NEN LPA LDY V LS EV KLN H+P + Sbjct: 538 AAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPAS 597 Query: 481 LGQASRISGVTPAALSLLLVHLKKGGL 507 +GQASRISGVTPAA+S+LLV LKK G+ Sbjct: 598 IGQASRISGVTPAAISILLVWLKKQGM 624 >ECs4683 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division Ecs Escherichia coli O157:H7 Length = 629 Score = 699 bits (1804), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/507 (66%), Positives = 403/507 (79%), Gaps = 7/507 (1%) Query: 1 VDDLMLEGDRVVGAVTQAGIRFAGRAVVLTAGTFLDGKIHVGLNNYSGGRAGDPPAVSLS 60 V+DL++E DRVVGAVTQ G++F +AVVLT GTFLDGKIH+GL+NYSGGRAGDPP++ LS Sbjct: 125 VEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLS 184 Query: 61 ARLKELKLPQGRLKTGTPPRIDGRSINLAILEEQPGDLDPVPVFSVMGNAAMHPRQMPCW 120 RL+EL L GRLKTGTPPRID R+I+ ++L +Q GD +P+PVFS MGNA+ HP+Q+PC+ Sbjct: 185 RRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGD-NPMPVFSFMGNASQHPQQVPCY 243 Query: 121 ITHTNSRTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIYLEPEGLT 180 ITHTN +THD+IR LDRSPMY GVIEGVGPRYCPSIEDK+ RFA ++ HQI+LEPEGLT Sbjct: 244 ITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLT 303 Query: 181 THEFYPNGISTSLPFDVQLELVRSMKGMENAHILRPGYAIEYDYYDPRGLKSSLETRQVQ 240 ++E YPNGISTSLPFDVQ+++VRSM+GMENA I+RPGYAIEYD++DPR LK +LE++ +Q Sbjct: 304 SNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQ 363 Query: 241 GLFFAGQINGTTGYEEAAAQGMLAGINAALQTQGREAWTPRRDEAYLGVLVDDLVTQGVQ 300 GLFFAGQINGTTGYEEAAAQG+LAG+NAA + +E W P R +AYLGVLVDDL T G + Sbjct: 364 GLFFAGQINGTTGYEEAAAQGLLAGLNAARLSDDKEGWAPARSQAYLGVLVDDLCTLGTK 423 Query: 301 EPYRMFTSRAEYRLSLREDNADLRLTEIGRELGCVGDAQWEAFDRKREAVSREMERLKST 360 EPYRMFTSRAEYRL LREDNADLRLTEIGRELG V D +W F+ K E + RE +RLKST Sbjct: 424 EPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKST 483 Query: 361 WVNPRILAAAEAERVLGKAIEREYNLLDLLRRPNVSYDSLMGLTGTEGQALAGPGIEDGP 420 WV P AAAE L + RE + DLLRRP ++Y+ L LT P + D Sbjct: 484 WVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPF------APALTDEQ 537 Query: 421 VREQVEIQVKYAGYIARQANEISRQDHNENLKLPADLDYMDVKALSIEVRQKLNKHRPET 480 EQVEIQVKY GYIARQ +EI +Q NEN LPA LDY V LS EV KLN H+P + Sbjct: 538 AAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPAS 597 Query: 481 LGQASRISGVTPAALSLLLVHLKKGGL 507 +GQASRISGVTPAA+S+LLV LKK G+ Sbjct: 598 IGQASRISGVTPAAISILLVWLKKQGM 624