BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0104.p (453 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0989 [KE] COG1167 Transcriptional regulators containing a DNA... 268 2e-71 PA5283 [KE] COG1167 Transcriptional regulators containing a DNA-... 259 8e-69 AGc398 [KE] COG1167 Transcriptional regulators containing a DNA-... 259 1e-68 SMb20039 [KE] COG1167 Transcriptional regulators containing a DN... 251 4e-66 BMEI0169 [KE] COG1167 Transcriptional regulators containing a DN... 250 5e-66 >RSc0989 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Rso Ralstonia solanacearum Length = 490 Score = 268 bits (685), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 150/397 (37%), Positives = 229/397 (57%), Gaps = 5/397 (1%) Query: 4 ASTTLTSTLVQLIRRQIAEGVYAPGSRLPSIREMAARHGCAKNTIVNVFDELTALGLAEP 63 A TL L + R +I E V+ G R+PSIR++A ++ T+V ++ L A G E Sbjct: 31 AQMTLVDQLTEWARMRIDERVFRAGMRMPSIRQLAQEKSISRFTVVEAYERLVAQGYLES 90 Query: 64 RRGAGFFVC--VAPPRPKEDEEGNLSRAMDVVWLMREQLKHDPGQLRLGDGFPPMEWLHD 121 RRG+GF+V AP + +R +DV WL+R + G GF P WL Sbjct: 91 RRGSGFYVKERQAPLPEEPPAPPASARKIDVAWLLRNMFHSAEPRKAPGIGFLPNGWLDG 150 Query: 122 VRLDKFHQKVVRTGIGALFGYGSRFGYLPLRQHLVHKLAQHGIEAGTGQIVLTHGANQAL 181 + + + R +G+ G+LPLRQ L +LA+ I A QIV+T G Q+L Sbjct: 151 ELIANALRALGRQNGNQFLAWGTPQGFLPLRQQLQTRLAELEIGARPDQIVMTSGITQSL 210 Query: 182 DIVIRHFIRPGDRVLVDEPGYYMLYGKLKLSGARIIGIPRLPDGPDVAVLERELQKPGKP 241 D++ R +++PGD VLV +P +++++G+ GA++IG+P +GPD+ LE +Q +P Sbjct: 211 DLIARQYVQPGDTVLVGDPAWFLMFGRFAAQGAQVIGVPYTTEGPDLVALEGLVQVR-RP 269 Query: 242 PLFFTQSLAHNPTASDTSPHKAHRILQLADRYQAIIVENDAFADFKPATAP--RIATLDQ 299 L S+ HNPT + S KA ++L+LA++Y +IVE+D + D P P R+A+LDQ Sbjct: 270 KLLVINSVLHNPTGTSLSAAKAFQLLRLAEQYGFLIVEDDIYGDLAPPGHPATRLASLDQ 329 Query: 300 LRRTVYVGSFSKSVSAALRVGFIACHRDLASDLADIKMLVHMSSSEYCERTLDVILSDGH 359 LRR +Y+GSFSK+++A LRVGFIACH +LA +L D K+L +++ E ER L +L++G Sbjct: 330 LRRVIYLGSFSKTLAANLRVGFIACHPELAKNLTDGKLLAGLATPEINERVLYKVLTEGQ 389 Query: 360 FSRHTARLRERLAQATGTGARPAGRAGRRTVLRAPAG 396 + +H R+R RL +A R R G + + AG Sbjct: 390 YRKHVERVRARLDRARDGVQRSLERLGLKLFAQQGAG 426 >PA5283 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Pae Pseudomonas aeruginosa Length = 458 Score = 259 bits (662), Expect = 8e-69, Method: Compositional matrix adjust. Identities = 139/369 (37%), Positives = 210/369 (56%), Gaps = 6/369 (1%) Query: 28 GSRLPSIREMAARHGCAKNTIVNVFDELTALGLAEPRRGAGFFVCVAPPRPKEDEEGNLS 87 G+R+PSIR++A + ++++++ +D L ALG+ E R G+GFFV AP D + Sbjct: 33 GTRIPSIRQLARENQLSQSSVIEAYDRLVALGMLESRHGSGFFVAEAPA-ATTDLDSEWH 91 Query: 88 RAMDVVWLMREQLKHDPGQLRLGDGFPPMEWLHDVRLDKFHQKVVRTGIGALFGYGSRFG 147 + W Q +L+LG G+ P W L ++V R+ + LF Y + G Sbjct: 92 EGAENAW---GQFSGSSTKLKLGCGWIPDSWREVEELSYAIRQVARSELAGLFDYSTPLG 148 Query: 148 YLPLRQHLVHKLAQHGIEAGTGQIVLTHGANQALDIVIRHFIRPGDRVLVDEPGYYMLYG 207 LRQH+ +L I QI+ T GA+ ALD+++R ++PGD V+V+ PGYY L+ Sbjct: 149 LPALRQHIQKRLRLIDIHVDPEQILTTTGASHALDLLVRTLLKPGDVVVVENPGYYNLFN 208 Query: 208 KLKLSGARIIGIPRLPDGPDVAVLERELQKPGKPPLFFTQSLAHNPTASDTSPHKAHRIL 267 LK G +++G+PR GPD A LE L + KP FT S+ HNPT + SP AHR+L Sbjct: 209 LLKFHGVKMLGVPRTRHGPDTAALETIL-RAHKPKFLFTNSMYHNPTGTSLSPSVAHRVL 267 Query: 268 QLADRYQAIIVENDAFADFKPATAPRIATLDQLRRTVYVGSFSKSVSAALRVGFIACHRD 327 QLA+++ IVE+D +ADF+ + R+ATLD LRR +Y+ SFSK++S +LRVG++ + Sbjct: 268 QLAEQHDFHIVEDDIYADFQNGPSTRLATLDSLRRVIYLASFSKTLSCSLRVGYLIAGPE 327 Query: 328 LASDLADIKMLVHMSSSEYCERTLDVILSDGHFSRHTARLRERLAQATGTGARPAGRAGR 387 L LAD+KM + S + E + +L++G + + RLR+RL + R G G Sbjct: 328 LIRRLADVKMYTSIGSQRFAECVVSTMLANGSYRKLVQRLRQRLTRQMAATLRVLGDNGW 387 Query: 388 RTVLRAPAG 396 V P G Sbjct: 388 E-VFAEPVG 395 >AGc398 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 449 Score = 259 bits (661), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 141/365 (38%), Positives = 206/365 (56%), Gaps = 2/365 (0%) Query: 16 IRRQIAEGVYAPGSRLPSIREMAARHGCAKNTIVNVFDELTALGLAEPRRGAGFFVC-VA 74 IR++I PG+RLPS+R +A + +TIV +D L A G R G+GFFV Sbjct: 5 IRQRITSRSLVPGARLPSVRALAKTMQLSTSTIVEAYDRLVADGTISSRPGSGFFVAGPL 64 Query: 75 PPRPKEDEEGNLSRAMDVVWLMREQLKHDPGQLRLGDGFPPMEWLHDVRLDKFHQKVVRT 134 P D E L RA+D +W+ R+ L + G G+ P W+ L + + + R Sbjct: 65 APLSLADIEPRLDRAVDPLWVSRQALDDGSALAKPGCGWLPASWMPQEALRRAMRGLARA 124 Query: 135 GIGALFGYGSRFGYLPLRQHLVHKLAQHGIEAGTGQIVLTHGANQALDIVIRHFIRPGDR 194 L YGS G LPLRQ L +LA+HG++AG QI+LT QA+D++ R ++PGD Sbjct: 125 DDALLTDYGSPMGLLPLRQLLSRRLAEHGVQAGASQIMLTDSGTQAIDLLCRFLLQPGDT 184 Query: 195 VLVDEPGYYMLYGKLKLSGARIIGIPRLPDGPDVAVLERELQKPGKPPLFFTQSLAHNPT 254 V+VD+P Y+ + L+ +I+G+P P GPD+ + E+ L K +P L+ T S HNPT Sbjct: 185 VVVDDPCYFNFHALLRAHRVKIVGVPYTPAGPDLPLFEQAL-KEHQPRLYITNSAIHNPT 243 Query: 255 ASDTSPHKAHRILQLADRYQAIIVENDAFADFKPATAPRIATLDQLRRTVYVGSFSKSVS 314 + S AHR+L LA++ I+E+D FADF+ APR+A D L R V +GSFSK++S Sbjct: 244 GARLSAVSAHRLLMLAEQPGLTIIEDDIFADFETQAAPRLAAFDGLNRVVQIGSFSKTLS 303 Query: 315 AALRVGFIACHRDLASDLADIKMLVHMSSSEYCERTLDVILSDGHFSRHTARLRERLAQA 374 A++R GFIA R L D+K+ + + + +L+DG + +H LR+RLA A Sbjct: 304 ASVRCGFIAAPRAWVEALTDLKIATAFGGTHFSAALVLSLLTDGSYRKHVEALRQRLAAA 363 Query: 375 TGTGA 379 A Sbjct: 364 VPEAA 368 >SMb20039 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Sme Sinorhizobium meliloti Length = 474 Score = 251 bits (640), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 150/395 (37%), Positives = 222/395 (56%), Gaps = 4/395 (1%) Query: 4 ASTTLTSTLVQLIRRQIAEGVYAPGSRLPSIREMAARHGCAKNTIVNVFDELTALGLAEP 63 A +L + ++ ++ +IA PG+RLPSIR A +K+T+V ++ L A G+ Sbjct: 16 AGESLIAKVMGTVKHRIAARSLTPGARLPSIRSFALAMKVSKSTVVEAYERLQAEGVIRS 75 Query: 64 RRGAGFFVCVAPPRPKEDEE--GNLSRAMDVVWLMREQLKHDPGQLRLGDGFPPMEWLHD 121 R G+GFFV AP P E + RA+D +W+ R+ L+ G LR G G+ P W+ + Sbjct: 76 RPGSGFFVA-APLAPLTLAEIGPRVDRAVDPLWISRQALEPGEGVLRPGCGWLPPHWMPE 134 Query: 122 VRLDKFHQKVVRTGIGALFGYGSRFGYLPLRQHLVHKLAQHGIEAGTGQIVLTHGANQAL 181 L + + + R L YG+ G LPLRQ L ++AQHGIEA QI+LT QA+ Sbjct: 135 EGLRRALRGIARGAAATLVDYGAPLGLLPLRQLLTRRVAQHGIEASPDQILLTESGTQAI 194 Query: 182 DIVIRHFIRPGDRVLVDEPGYYMLYGKLKLSGARIIGIPRLPDGPDVAVLERELQKPGKP 241 D++ R ++PGD VLVD+P Y+ + L+ ARI G+P P GPD+ L + KP Sbjct: 195 DLLCRFLLKPGDAVLVDDPCYFNFHALLRAHQARIFGVPYTPSGPDIGRFAEALAE-HKP 253 Query: 242 PLFFTQSLAHNPTASDTSPHKAHRILQLADRYQAIIVENDAFADFKPATAPRIATLDQLR 301 L+ T S HNPT + SP HR+L+LA++ I+E+D FADF+ APR+A D L Sbjct: 254 RLYITNSALHNPTGAMLSPLVGHRLLKLAEQAGLTIIEDDIFADFEETPAPRLAAFDGLE 313 Query: 302 RTVYVGSFSKSVSAALRVGFIACHRDLASDLADIKMLVHMSSSEYCERTLDVILSDGHFS 361 R V++GSFSK++SAA+R GFI RD L D+K+ ++ + + +L +G + Sbjct: 314 RVVHIGSFSKTLSAAVRCGFIVAPRDWVEALTDLKIATCFGAAGFSSELVLTLLKNGSYR 373 Query: 362 RHTARLRERLAQATGTGARPAGRAGRRTVLRAPAG 396 +H +R+RLA A A+ R G + AG Sbjct: 374 KHMETVRQRLAGAMAETAQRLARIGITPWIEPQAG 408 >BMEI0169 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Bme Brucella melitensis Length = 484 Score = 250 bits (639), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 135/375 (36%), Positives = 206/375 (54%), Gaps = 15/375 (4%) Query: 8 LTSTLVQLIRRQIAEGVYAPGSRLPSIREMAARHGCAKNTIVNVFDELTALGLAEPRRGA 67 L ++ +IR +I APG+RLPSIR +A +K+T+V +D L A G+ + RRGA Sbjct: 27 LVEKVMGIIRGRITAMSLAPGARLPSIRRLAETMNVSKSTVVEAYDRLVAEGIIQSRRGA 86 Query: 68 GFFVC--------VAPPRPKEDEEGNLSRAMDVVWLMREQLKHDPGQLRLGDGFPPMEWL 119 GF+V +A P +D R +D W+MR+ L+ + L+ G G+ P WL Sbjct: 87 GFYVSERARQPFSLAATAPHKD------RQIDPFWVMRQSLEAESRTLKPGCGWLPDGWL 140 Query: 120 HDVRLDKFHQKVVRTGIGALFGYGSRFGYLPLRQHLVHKLAQHGIEAGTGQIVLTHGANQ 179 L + + + R L YG G+ PLRQHL H+L + GI+ G+I+LT Q Sbjct: 141 PQEALRRALRTIARDDQSNLTTYGEPLGFRPLRQHLAHRLGEQGIDIAGGEILLTDSGTQ 200 Query: 180 ALDIVIRHFIRPGDRVLVDEPGYYMLYGKLKLSGARIIGIPRLPDGPDVAVLERELQKPG 239 A+D++ R+ ++PGD VLVD+P Y+ L +++G+P GPD+ + Sbjct: 201 AIDLICRYLLQPGDTVLVDDPCYFNFQAVLLTHRVKLVGVPYTHSGPDLDAFANAATEHA 260 Query: 240 KPPLFFTQSLAHNPTASDTSPHKAHRILQLADRYQAIIVENDAFADFKPATAPRIATLDQ 299 P L+ + + HNPT +P AHR+L+LA+ + +VE++ F DF P+ P +A LD Sbjct: 261 -PKLYISNAGLHNPTGGIMTPATAHRLLKLAEAHGITLVEDNIFGDFHPSPTPLLAELDG 319 Query: 300 LRRTVYVGSFSKSVSAALRVGFIACHRDLASDLADIKMLVHMSSSEYCERTLDVILSDGH 359 R +++GSFSK++SAA RVG+IA RD L D+K+ + + + +L DG Sbjct: 320 FERVLHIGSFSKTLSAAARVGYIAGRRDWIEGLTDLKLATSFGCNALSPQIVHALLIDGT 379 Query: 360 FSRHTARLRERLAQA 374 + RH LR RLA A Sbjct: 380 YRRHIESLRTRLADA 394