BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0074.p (533 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cj1687 [GEPR] COG0477 Permeases of the major facilitator superfa... 139 1e-32 AGc4286 [GEPR] COG0477 Permeases of the major facilitator superf... 132 2e-30 MA0181 [GEPR] COG0477 Permeases of the major facilitator superfa... 72 2e-12 DR0472 [GEPR] COG0477 Permeases of the major facilitator superfa... 68 7e-11 MA1516 [GEPR] COG0477 Permeases of the major facilitator superfa... 62 5e-09 >Cj1687 [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 423 Score = 139 bits (351), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 106/363 (29%), Positives = 178/363 (49%), Gaps = 19/363 (5%) Query: 23 SSLTIMGSVMIAPMLPKITAEFA-------AVEADALTLAPL------IVAGPALAIALF 69 +++T++GSV+I+ LP I F A A + TLA L ++ PA+ + + Sbjct: 36 AAMTMLGSVVISSALPAINRHFEELLTQSGATLASSFTLAHLDILVRLVLTIPAIFVVIL 95 Query: 70 APVAGMLADRFGRKSMLLLGCLLYALFGALPVLLHEIRLILLSRLLFGCAEALIMTCCTT 129 +P AG+L D+FG+ +L +++ L G L++I IL SR +FG A A IMT + Sbjct: 96 SPFAGILMDKFGKLKFILPAMVVWTLSGISGFFLNDIYAILTSRAIFGMATAFIMTGASA 155 Query: 130 LIADYWPP---RERMRYINRQVITIGVVGALFFVIGGVAGEGSWRTPFLLY-LTPLLMLP 185 L+ DY+ R ++ Q V GA+F I G SWR PFL+Y L L+ L Sbjct: 156 LLGDYYSRGGFNRRENALSLQGFFCAVGGAVFISIAGFVSSYSWRYPFLVYGLGILITLM 215 Query: 186 AIVAWLWEPDRRQEDSHAAPALNGGVRRTVLTACFLIFAGMVTCFVVTVMTPTVLVMRGV 245 AI+ +L+EP + + +H + F+ F MV ++ P + Sbjct: 216 AII-YLFEPRKFKFYNHTKIETKTNYWQ-FFPIYFIGFFIMVVYYISPTQLPYYIEEHLG 273 Query: 246 TSTSLIGAAAGLAILCTLIGSIAWPFVRERIGVAGVNALLLGCMAAGLCVLALAPSYAVV 305 IG + ++ LC S+++ ++ + + + + L L ++ +L L S+ V Sbjct: 274 LDPKYIGISMSVSALCYGFFSLSYRYIIKFLSIKTIYVLTLFIVSCSFLLLFLVDSFFTV 333 Query: 306 LAAMVLQGLGAGFLVSNASLPLLLGLPPHLRARGVGAFTACLYLGQFASPLIITAIAQPL 365 L A+ L G+G G ++ N + L P + R+R G +C++LGQF SP+I I + + Sbjct: 334 LIALALLGMGGGIMLVNNTAYLFSICPENARSRAYGILASCIFLGQFLSPIISQPIVRQM 393 Query: 366 GPV 368 G V Sbjct: 394 GLV 396 >AGc4286 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 400 Score = 132 bits (333), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 116/349 (33%), Positives = 177/349 (50%), Gaps = 8/349 (2%) Query: 13 PRQGLVIQLASSLTIMGSVMIAPMLPKITAEFAAVEADALTLAPLIVAGPALAIALFAPV 72 P L + ++LTIM +AP LP I F + D ++ +++ P++ +AL AP+ Sbjct: 6 PALKLTLLFVATLTIMAGTTVAPSLPAIEQSFLSTP-DVEIMSRMVLTLPSVFVALCAPI 64 Query: 73 AGMLADRFGRKSMLLLGCLLYALFGALPVLLHEIRLILLSRLLFGCAEALIMTCCTTLIA 132 AG+LADRFGRK +LL LLY+L G + + +L+ R G A IMT T L+ Sbjct: 65 AGVLADRFGRKRLLLGAILLYSLSGISGLFADSLAGLLVGRAFLGLAIGGIMTIGTALVG 124 Query: 133 DYWPPRERMRYINRQVITIGVVGALFFVIGGVAGEGSWRTPFLLYLTPLLMLPAIVAWLW 192 DY+ R RY+ Q + G +F V GG + WR PF +Y LL+LPA + +L Sbjct: 125 DYFEGPARERYLGLQQAFTQLGGVVFVVAGGWLADIHWRAPFAVYAVALLILPAALFFLR 184 Query: 193 EPDRRQ----EDSHAAPALNGGVRRTVLTACFLIFAGMVTCFVVTVMTPTVLVMRGVTST 248 EP R ++ A+N + A FL+ A + + P L GV S Sbjct: 185 EPARNSSRATQNGEQGLAVNWLPVAVLAMAVFLVNA---LFYTIPSQLPFFLREFGVLSG 241 Query: 249 SLIGAAAGLAILCTLIGSIAWPFVRERIGVAGVNALLLGCMAAGLCVLALAPSYAVVLAA 308 S+ G A G+ L + ++++ +R RIGV + A L MA G +LA A + +L+A Sbjct: 242 SVAGYAIGIFNLAGALMALSFGRLRARIGVTVILAAGLVLMATGFALLATAGGLSSMLSA 301 Query: 309 MVLQGLGAGFLVSNASLPLLLGLPPHLRARGVGAFTACLYLGQFASPLI 357 + + G G G ++ + ++ P LR R G TA ++LG F SPL+ Sbjct: 302 LAVVGAGLGAVMPSIMSTTIMLAPLRLRGRIAGIVTASMFLGHFISPLV 350 >MA0181 [GEPR] COG0477 Permeases of the major facilitator superfamily Mac Methanosarcina acetivorans str.C2A Length = 410 Score = 72.4 bits (176), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 89/349 (25%), Positives = 164/349 (46%), Gaps = 39/349 (11%) Query: 29 GSVMIAPMLPKITAEFAAVEADALTLAPLIVAGPALAIALFAPVAGMLADRFGRKSMLLL 88 G ++AP+LP + + L+++ A++ A+FA V G DR RK +L+ Sbjct: 30 GGSLLAPVLPDMVEPLNTTSHEV----GLLISTYAISTAIFALVIGHFIDRVNRKKILVP 85 Query: 89 GCLLYALFGALPVLLHEIRLILLSRLLFGCAEALIMTCCTTLIADYWPPRERMRYINR-- 146 ++Y L G + ++ +L+ R + G A +M+ +IAD + + + +N+ Sbjct: 86 CLVIYGLTGLVSYFTSDLHSLLILRFIQGIGVAGMMSLPMLVIADVYKDHKSLYAMNKVS 145 Query: 147 QVITIGVVGALFFVIGGVAGEGSWRTPFLLYLTPLLMLP-AIVAWLWEPDRR-QEDSHAA 204 + IG V A +IGG W PFL Y +L LP A V + P+ R Q D+ + Sbjct: 146 MALAIGSVSAP--LIGGGLANLGWNYPFLFY---VLSLPLAFVVMFFLPETRVQRDNVSH 200 Query: 205 PALNGGV----RRTVLTACFLIFAGMVTCFVVTVMTPTVLVMRGVTSTS-----LIGAAA 255 + G +L FL FA V + +V+T +++ V S + LI A Sbjct: 201 KGILDGFTALKEMRILYTVFLSFA--VFFILYSVLTYVPFMLKNVLSYTAKESGLILAFQ 258 Query: 256 GLAILCTLIGSIAWPFVRERIGVAGVNALLL----GCMAAGLCVLALAPSYAVVLAAMVL 311 G+AI+ + P V+ +A ++ +L G GL + +++ +Y++V +++ Sbjct: 259 GIAIILMV------PRVKT---LASKHSTILIIAIGFALDGLAIFSISFAYSIVTVLLLI 309 Query: 312 QGLGAGFLVSNASLP-LLLGLPPHLRARGVGAFTACL-YLGQFASPLII 358 GAGF +S ++ ++ + P GV + + Y+GQ SP+++ Sbjct: 310 LLFGAGFGLSQTAIDAQIVQIAPSESKGGVLSIHNTMKYIGQSLSPILL 358 >DR0472 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 407 Score = 67.8 bits (164), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 61/189 (32%), Positives = 88/189 (46%), Gaps = 13/189 (6%) Query: 17 LVIQLASSLTIMGSVMIAPMLPKITAEFAAVEADALTLAPLIVAGPALAIALFAPVAGML 76 L I L + + +MG +I P+LP + E A EA ++ A A +FAP+ G L Sbjct: 12 LFILLTALIDVMGIGLIIPVLPGLVKELAGSEAGGARFIGVLTAAYAAMQFIFAPILGTL 71 Query: 77 ADRFGRKSMLLLGCLLYALFGALPVLLHEIRLILLSRLLFGCAEALIMTCCTTLIADYWP 136 +DRFGR+ +LLL L L + +L+ RL+ G A +T IAD Sbjct: 72 SDRFGRRPVLLLSLAGMVLDYLLLFFSPNLWWLLVGRLIAGVTGA-SLTVANAYIADVTA 130 Query: 137 PRERMRYINRQVITIGVVGALFFVIGGVAGEGSWRTPFLL--------YLTPLLMLPAIV 188 P +R + R T GV L ++GG GE R PFL +L LL+LP + Sbjct: 131 PEDRAKNFGRLGATWGVGFILGPMLGGWLGEHGLRAPFLFAAGLTALNFLYGLLVLPESL 190 Query: 189 AWLWEPDRR 197 P++R Sbjct: 191 ----PPEKR 195 >MA1516 [GEPR] COG0477 Permeases of the major facilitator superfamily Mac Methanosarcina acetivorans str.C2A Length = 470 Score = 61.6 bits (148), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 14/170 (8%) Query: 32 MIAPMLPKITAEFAAVEADALTLAPLIVAGPALAIALFAPVAGMLADRFGRKSMLLLGCL 91 ++ P+LP++ A E D ++VA LA ALF PV GM ADR RK+ LL+ CL Sbjct: 25 LLGPVLPEMLAPLKTAEQDI----GMVVAVFTLATALFTPVFGMFADRLSRKT-LLIPCL 79 Query: 92 LYALFGALPVLL-HEIRLILLSRLLFGCAEALIMTCCTTLIADYWPPRERMRYINRQVIT 150 + F L + +L+ R + G A ++ LI D +P ER+ +R +T Sbjct: 80 VLNGFSGLACYFAQDFETLLIFRFVQGIGAAGMLLLALLLIGDLYPGHERVHATSRVGMT 139 Query: 151 --IGVVGALFFVIGGVAGEGSWRTPFLLYLTPLLMLP-AIVAWLWEPDRR 197 IG+V F V+GG+ SW PFL Y L+LP A+ A ++ P + Sbjct: 140 SAIGLVS--FPVLGGLMALKSWNFPFLFY---GLVLPLAVFASIFLPGGK 184