BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0064.p (246 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1633 [IQR] COG1028 Dehydrogenases with different specificitie... 407 e-113 XF0319 [IQR] COG1028 Dehydrogenases with different specificities... 327 2e-89 CC0511 [IQR] COG1028 Dehydrogenases with different specificities... 253 4e-67 VCA0691 [IQR] COG1028 Dehydrogenases with different specificitie... 246 2e-65 SMc03878 [IQR] COG1028 Dehydrogenases with different specificiti... 239 4e-63 >RSc1633 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 246 Score = 407 bits (1046), Expect = e-113, Method: Compositional matrix adjust. Identities = 193/246 (78%), Positives = 221/246 (89%) Query: 1 MSKRIAYVTGGMGGIGTAICTRLCKDGYTVVAGCGPNSTRKDKWLATMREQGFDIHASEG 60 M+KRIAYVTGGMGGIGTAIC RL +D + VVAGCGPNS RKDKWL RE GFD ASEG Sbjct: 1 MTKRIAYVTGGMGGIGTAICQRLARDDFIVVAGCGPNSPRKDKWLEQQRELGFDFIASEG 60 Query: 61 NVSNWESTKAAFEKVRAEIGEVDVLVNNAGITRDGQFRKMSKDDWDAVIDTNLNSLFNVT 120 NV++W+S+KAAF+KV+AE+GEVDVL+NNAGITRD FRKM++ DWDAVI TNL SLFNVT Sbjct: 61 NVADWDSSKAAFDKVKAEVGEVDVLINNAGITRDVVFRKMTRSDWDAVIGTNLTSLFNVT 120 Query: 121 KQVIEGMCERGFGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNT 180 KQVI+GM +RG+GRI+NISSVNGQKGQFGQTNYSTAKAG+HGFTMALAQEVATKGVTVNT Sbjct: 121 KQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT 180 Query: 181 VSPGYIGTDMVRAIRPEVLEKIVSGIPVKRLGEPEEIASIVAWIASSEGGYATGSDFSLN 240 VSPGYI TDMV+AIR +VL+KI+ IPVKRLG+P EIASI AW+AS E G++TG+DFSLN Sbjct: 181 VSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGDPNEIASICAWLASEESGFSTGADFSLN 240 Query: 241 GGLYMG 246 GGL+MG Sbjct: 241 GGLHMG 246 >XF0319 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Xfa Xylella fastidiosa 9a5c Length = 246 Score = 327 bits (838), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 147/245 (60%), Positives = 193/245 (78%) Query: 1 MSKRIAYVTGGMGGIGTAICTRLCKDGYTVVAGCGPNSTRKDKWLATMREQGFDIHASEG 60 M+ RIAYVT GMG IGTAIC +L ++G+TVVAGCGPNS RK WL RE GFD ASEG Sbjct: 1 MTLRIAYVTSGMGSIGTAICQKLARNGHTVVAGCGPNSPRKANWLREQRELGFDFIASEG 60 Query: 61 NVSNWESTKAAFEKVRAEIGEVDVLVNNAGITRDGQFRKMSKDDWDAVIDTNLNSLFNVT 120 N ++W+ST +AF KV+AE+GE+DVLVNNAG RD FR+M ++DW++VI +NLNSLFN+T Sbjct: 61 NAADWDSTVSAFAKVKAEVGEIDVLVNNAGNNRDMLFRQMGREDWNSVISSNLNSLFNIT 120 Query: 121 KQVIEGMCERGFGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNT 180 KQVI+ M R +GRI+NI SV+ KGQ GQ NY+TAKA +HGFT ALAQEVAT+ VTVNT Sbjct: 121 KQVIDAMTARNWGRIVNIGSVSAHKGQIGQVNYATAKAAMHGFTRALAQEVATRNVTVNT 180 Query: 181 VSPGYIGTDMVRAIRPEVLEKIVSGIPVKRLGEPEEIASIVAWIASSEGGYATGSDFSLN 240 +SPGYI + + + P+VL+++ + +P++RLG+ EE+A + AW+ S E Y TG+D+++N Sbjct: 181 ISPGYIASAAISSFPPDVLDRLANSVPMRRLGKAEEVAGLCAWLVSDEAAYVTGADYAVN 240 Query: 241 GGLYM 245 GGL M Sbjct: 241 GGLRM 245 >CC0511 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 240 Score = 253 bits (645), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 131/242 (54%), Positives = 166/242 (68%), Gaps = 5/242 (2%) Query: 4 RIAYVTGGMGGIGTAICTRLCKDGYTVVAGCGPNSTRKDKWLATMREQGFDIHASEGNVS 63 R+A+VTGG GIG AIC RL DG+ V AG N + + + +GNV Sbjct: 3 RVAFVTGGTRGIGRAICERLIADGHKVAAGYSGNEAAAEACAKEL-----GVMVVKGNVG 57 Query: 64 NWESTKAAFEKVRAEIGEVDVLVNNAGITRDGQFRKMSKDDWDAVIDTNLNSLFNVTKQV 123 +E +AA +KV AE+G +D+LVNNAGITRDG KM+ + W VI N++S FN+T+ V Sbjct: 58 VFEDCQAAVKKVEAELGPIDILVNNAGITRDGMLHKMTYEQWSEVIRVNMDSAFNMTRPV 117 Query: 124 IEGMCERGFGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNTVSP 183 IEGM +R +GRIINISS+NGQKGQ GQTNYS AKAG+ GFT ALA E A KGVTVN + P Sbjct: 118 IEGMRDRSWGRIINISSINGQKGQMGQTNYSAAKAGLIGFTKALALENAKKGVTVNVICP 177 Query: 184 GYIGTDMVRAIRPEVLEKIVSGIPVKRLGEPEEIASIVAWIASSEGGYATGSDFSLNGGL 243 GYI T+MV A+ VL +IV+GIPV RLG EEIA +V+++A G+ TG+ +LNGG Sbjct: 178 GYIDTEMVAAVPENVLAQIVAGIPVGRLGRGEEIADMVSFLAGERAGFVTGATLTLNGGQ 237 Query: 244 YM 245 YM Sbjct: 238 YM 239 >VCA0691 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Vch Vibrio cholerae Length = 246 Score = 246 bits (629), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 128/244 (52%), Positives = 161/244 (65%), Gaps = 1/244 (0%) Query: 3 KRIAYVTGGMGGIGTAICTRLCKDGYTVVAGCGP-NSTRKDKWLATMREQGFDIHASEGN 61 ++IA +TG GGIG+AI T+L +GY V+A N W + + E + Sbjct: 2 RKIALITGSKGGIGSAISTQLVSEGYRVIATYYTGNYQCALDWFNEKQFTEDQVRLLELD 61 Query: 62 VSNWESTKAAFEKVRAEIGEVDVLVNNAGITRDGQFRKMSKDDWDAVIDTNLNSLFNVTK 121 V+N E K+ E G +DV+VNNAGITRD F+KM W VIDTNLNS+FNVT+ Sbjct: 62 VTNTEECAERLAKLLEEEGTIDVVVNNAGITRDSVFKKMPHQAWKEVIDTNLNSVFNVTQ 121 Query: 122 QVIEGMCERGFGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNTV 181 + MCE+GFGRIINISSVNG KGQFGQTNYS AKAG+ GF+ ALA E A GVTVN + Sbjct: 122 PLFAAMCEKGFGRIINISSVNGLKGQFGQTNYSAAKAGMIGFSKALAAEGARYGVTVNVI 181 Query: 182 SPGYIGTDMVRAIRPEVLEKIVSGIPVKRLGEPEEIASIVAWIASSEGGYATGSDFSLNG 241 +PGY T MV +R EVL+ IV +P+KRL +PEEIA+ V+++AS Y TG S+NG Sbjct: 182 APGYTLTPMVEQMRAEVLQSIVDQVPMKRLAKPEEIANAVSYLASDAAAYITGETLSVNG 241 Query: 242 GLYM 245 GLYM Sbjct: 242 GLYM 245 >SMc03878 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 241 Score = 239 bits (610), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 128/243 (52%), Positives = 160/243 (65%), Gaps = 6/243 (2%) Query: 4 RIAYVTGGMGGIGTAICTRLCKDGYTVVAGCGPNSTRKDKWLATMREQGFDIHASEGNVS 63 R+A VTGG GIG AIC L GY V A N R + EQ I + +VS Sbjct: 3 RVALVTGGSRGIGAAICVALKAAGYKVAANYAGNDERAKAF-----EQESGIPVYKWDVS 57 Query: 64 NWESTKAAFEKVRAEIGEVDVLVNNAGITRDGQFRKMSKDDWDAVIDTNLNSLFNVTKQV 123 ++++ +V A++G VD+LVNNAGITRD F KM+ + W VI TNL +FN+T + Sbjct: 58 SYQACVDGIARVEADLGPVDILVNNAGITRDAMFHKMTPEQWGEVIGTNLTGVFNMTHPL 117 Query: 124 IEGMCERGFGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNTVSP 183 GM +RGFGRI+NISS+NGQKGQ GQ NYS AKAG G T ALAQE A KG+TVN + P Sbjct: 118 WSGMRDRGFGRIVNISSINGQKGQMGQVNYSAAKAGDLGLTKALAQEGAAKGITVNAICP 177 Query: 184 GYIGTDMVRAIRPEVL-EKIVSGIPVKRLGEPEEIASIVAWIASSEGGYATGSDFSLNGG 242 GYIGT+MVRA+ +VL E+I+ IPV RLGEPEE+A V ++AS + G+ TGS S NGG Sbjct: 178 GYIGTEMVRAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLASDDAGFITGSTISANGG 237 Query: 243 LYM 245 Y Sbjct: 238 QYF 240