BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0034.p (270 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1270 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple... 452 e-127 NMB0956 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple... 418 e-117 NMA1150 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple... 417 e-116 DR0083 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex... 353 3e-97 YPO1114 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple... 352 5e-97 >RSc1270 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Rso Ralstonia solanacearum Length = 418 Score = 452 bits (1164), Expect = e-127, Method: Compositional matrix adjust. Identities = 223/275 (81%), Positives = 251/275 (91%), Gaps = 5/275 (1%) Query: 1 VTKGDVLGALSAPAAAPAAAAKPA----LAQVAAPVK-AGLESRPEQRVPMSRLRARVAE 55 +TKGDVLGA++ A AAA A L QVAAPV A L RPE+RVPMSRLRAR+AE Sbjct: 144 ITKGDVLGAVAGGAKPAPAAAPQAARPALQQVAAPVDFAVLGDRPEERVPMSRLRARIAE 203 Query: 56 RLVQSQSTNAILTTFNEINMQPVIDLRNKYKDKFEKEHGVKLGFMSFFVKAVVHALKKYP 115 RLVQSQSTNAILTTFNE+NM+PV+DLR K+KD+FEK HGVKLGFMSFFVKA VHALKKYP Sbjct: 204 RLVQSQSTNAILTTFNEVNMKPVMDLRAKFKDQFEKTHGVKLGFMSFFVKAAVHALKKYP 263 Query: 116 IVNASVDGNDIVYHGYFDIGVAVGSPRGLVVPILRDADQMSIADIEKKIGEFGQKAKDGK 175 ++NASVDGNDIVYHGYFDIG+AVGSPRGLVVPILR+ADQMS+ADIEKKI EFGQKA+DGK Sbjct: 264 VINASVDGNDIVYHGYFDIGIAVGSPRGLVVPILRNADQMSLADIEKKIAEFGQKARDGK 323 Query: 176 LSIEELSGGTFTVSNGGTFGSMLSTPIINPPQSAILGIHATKERAVVENGQVVVRPINYF 235 L++++L+GGTF++SNGGTFGSMLSTPIINPPQSAILG+HATK+RAVVENGQVVVRP+NY Sbjct: 324 LTLDDLTGGTFSISNGGTFGSMLSTPIINPPQSAILGVHATKDRAVVENGQVVVRPMNYL 383 Query: 236 ALSYDHRIIDGREAVLSLVAIKEALEDPARLLLDL 270 A+SYDHRIIDGREAVL LVA+KEALEDPARLLLDL Sbjct: 384 AMSYDHRIIDGREAVLGLVAMKEALEDPARLLLDL 418 >NMB0956 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Nme Neisseria meningitidis MC58 Length = 393 Score = 418 bits (1074), Expect = e-117, Method: Compositional matrix adjust. Identities = 194/232 (83%), Positives = 220/232 (94%) Query: 39 RPEQRVPMSRLRARVAERLVQSQSTNAILTTFNEINMQPVIDLRNKYKDKFEKEHGVKLG 98 RPE+RVPMSRLRARVAERL+ SQ NAILTTFNE+NM+P++DLR KYK+KFEKEHGVKLG Sbjct: 162 RPEERVPMSRLRARVAERLLASQQENAILTTFNEVNMKPIMDLRAKYKEKFEKEHGVKLG 221 Query: 99 FMSFFVKAVVHALKKYPIVNASVDGNDIVYHGYFDIGVAVGSPRGLVVPILRDADQMSIA 158 FMSFFVKA V ALKKYP+VNASVDG DIVYHGYFDIG+A+GSPRGLVVPILRDADQMSIA Sbjct: 222 FMSFFVKAAVAALKKYPVVNASVDGKDIVYHGYFDIGIAIGSPRGLVVPILRDADQMSIA 281 Query: 159 DIEKKIGEFGQKAKDGKLSIEELSGGTFTVSNGGTFGSMLSTPIINPPQSAILGIHATKE 218 DIE+ I ++ +KAKDGK++IE+L+GGTF+++NGGTFGSM+STPIINPPQSAILG+HATKE Sbjct: 282 DIEQAIVDYAKKAKDGKIAIEDLTGGTFSITNGGTFGSMMSTPIINPPQSAILGMHATKE 341 Query: 219 RAVVENGQVVVRPINYFALSYDHRIIDGREAVLSLVAIKEALEDPARLLLDL 270 RAVVENGQVVVRP+ Y ALSYDHRIIDGREAVL+LVAIK+ALEDPARLLLDL Sbjct: 342 RAVVENGQVVVRPMMYLALSYDHRIIDGREAVLTLVAIKDALEDPARLLLDL 393 >NMA1150 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes NmA Neisseria meningitidis Z2491 Length = 403 Score = 417 bits (1073), Expect = e-116, Method: Compositional matrix adjust. Identities = 194/232 (83%), Positives = 220/232 (94%) Query: 39 RPEQRVPMSRLRARVAERLVQSQSTNAILTTFNEINMQPVIDLRNKYKDKFEKEHGVKLG 98 RPE+RVPMSRLRARVAERL+ SQ NAILTTFNE+NM+P++DLR KYK+KFEKEHGVKLG Sbjct: 172 RPEERVPMSRLRARVAERLLASQQENAILTTFNEVNMKPIMDLRAKYKEKFEKEHGVKLG 231 Query: 99 FMSFFVKAVVHALKKYPIVNASVDGNDIVYHGYFDIGVAVGSPRGLVVPILRDADQMSIA 158 FMSFFVKA V ALKKYP+VNASVDG DIVYHGYFDIG+A+GSPRGLVVPILRDADQMSIA Sbjct: 232 FMSFFVKAAVAALKKYPVVNASVDGKDIVYHGYFDIGIAIGSPRGLVVPILRDADQMSIA 291 Query: 159 DIEKKIGEFGQKAKDGKLSIEELSGGTFTVSNGGTFGSMLSTPIINPPQSAILGIHATKE 218 DIE+ I ++ +KAKDGK++IE+L+GGTF+++NGGTFGSM+STPIINPPQSAILG+HATKE Sbjct: 292 DIEQAIVDYAKKAKDGKIAIEDLTGGTFSITNGGTFGSMMSTPIINPPQSAILGMHATKE 351 Query: 219 RAVVENGQVVVRPINYFALSYDHRIIDGREAVLSLVAIKEALEDPARLLLDL 270 RAVVENGQVVVRP+ Y ALSYDHRIIDGREAVL+LVAIK+ALEDPARLLLDL Sbjct: 352 RAVVENGQVVVRPMMYLALSYDHRIIDGREAVLTLVAIKDALEDPARLLLDL 403 >DR0083 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Dra Deinococcus radiodurans Length = 417 Score = 353 bits (905), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 157/232 (67%), Positives = 198/232 (85%) Query: 39 RPEQRVPMSRLRARVAERLVQSQSTNAILTTFNEINMQPVIDLRNKYKDKFEKEHGVKLG 98 RPE+RVPM+R+RAR+AERL + Q+T A+LTTFNE+NMQP ++LR KY+D+F K+HGVKLG Sbjct: 186 RPEERVPMTRIRARIAERLKEVQNTAALLTTFNEVNMQPTMELRKKYQDQFVKKHGVKLG 245 Query: 99 FMSFFVKAVVHALKKYPIVNASVDGNDIVYHGYFDIGVAVGSPRGLVVPILRDADQMSIA 158 FMS FV+A ALK +P+VNASVDG D++YHGY+DIG+AV S RGLVVPILRD D MS+A Sbjct: 246 FMSLFVRAATEALKAFPMVNASVDGKDVIYHGYYDIGIAVASERGLVVPILRDTDNMSLA 305 Query: 159 DIEKKIGEFGQKAKDGKLSIEELSGGTFTVSNGGTFGSMLSTPIINPPQSAILGIHATKE 218 DIEK+I EF +A+ GKL++E++SGGTF+++NGGTFGSM+STPIIN PQSAILG+H E Sbjct: 306 DIEKQIAEFATRARAGKLTMEDMSGGTFSITNGGTFGSMMSTPIINAPQSAILGMHNIIE 365 Query: 219 RAVVENGQVVVRPINYFALSYDHRIIDGREAVLSLVAIKEALEDPARLLLDL 270 R + +NGQVV+ P+ Y A+SYDHR+IDG+EAV LV IK LEDPAR+LLDL Sbjct: 366 RPIAQNGQVVIAPMMYLAVSYDHRLIDGKEAVQFLVMIKNLLEDPARMLLDL 417 >YPO1114 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Ype Yersinia pestis Length = 407 Score = 352 bits (903), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 157/232 (67%), Positives = 197/232 (84%) Query: 39 RPEQRVPMSRLRARVAERLVQSQSTNAILTTFNEINMQPVIDLRNKYKDKFEKEHGVKLG 98 R E+RVPMSRLR RVAERL++++++ A+LTTFNEINMQP++DLR +Y + FEK HGV+LG Sbjct: 176 RSEKRVPMSRLRKRVAERLLEAKNSTAMLTTFNEINMQPIMDLRKQYGEAFEKRHGVRLG 235 Query: 99 FMSFFVKAVVHALKKYPIVNASVDGNDIVYHGYFDIGVAVGSPRGLVVPILRDADQMSIA 158 FMSF++KAVV ALK+YP VNAS+DG D+VYH YFD+ +AV +PRGLV P+LRD D +S+A Sbjct: 236 FMSFYIKAVVEALKRYPEVNASIDGEDVVYHNYFDVSIAVSTPRGLVTPVLRDVDTLSMA 295 Query: 159 DIEKKIGEFGQKAKDGKLSIEELSGGTFTVSNGGTFGSMLSTPIINPPQSAILGIHATKE 218 DIEKKI E K +DGKL +EEL+GG FT++NGG FGS++STPIINPPQSAILG+HA K+ Sbjct: 296 DIEKKIKELAVKGRDGKLKVEELTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKD 355 Query: 219 RAVVENGQVVVRPINYFALSYDHRIIDGREAVLSLVAIKEALEDPARLLLDL 270 R + NGQVV+ P+ Y ALSYDHR+IDGRE+V LV +KE LEDPARLLLD+ Sbjct: 356 RPMAVNGQVVILPMMYLALSYDHRLIDGRESVGYLVTVKEMLEDPARLLLDV 407