BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0017.p (420 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1215 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 694 0.0 NMA1524 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 575 e-164 NMB1310 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 575 e-164 XF2575 [I] COG0821 Enzyme involved in the deoxyxylulose pathway ... 561 e-159 BMEI0269 [I] COG0821 Enzyme involved in the deoxyxylulose pathwa... 556 e-158 >RSc1215 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Rso Ralstonia solanacearum Length = 431 Score = 694 bits (1791), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/415 (80%), Positives = 369/415 (88%) Query: 1 MSSSPIASGPLVRRNSRRVVISHGGREIVVGGGAPVMVQSMTNTDTADAIGTAIQIKDLA 60 + +P GPL RR+SR I G R + VGG APV VQSMTNTDTADAIGTAIQ+K+LA Sbjct: 7 VDCAPALPGPLPRRHSRAAEIRWGERLVRVGGDAPVCVQSMTNTDTADAIGTAIQVKELA 66 Query: 61 RAGSEVVRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTEYPECAQALSK 120 R GSE+VR+TVNTPEAAAAVPAIREQLDRMG+DVPLVGDFHYNGH LL ++P CA+ALSK Sbjct: 67 RTGSELVRITVNTPEAAAAVPAIREQLDRMGIDVPLVGDFHYNGHKLLQDHPACAEALSK 126 Query: 121 YRINPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENADRAEPW 180 YRINPGNVG+GAKRDTQFAQMIE AC+Y KPVRIGVNWGSLDQ LLARIMDENA RA PW Sbjct: 127 YRINPGNVGQGAKRDTQFAQMIETACRYGKPVRIGVNWGSLDQDLLARIMDENAQRAAPW 186 Query: 181 SAQAVMYEALVTSAIENAQRAEELGMAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHL 240 A+AVM EAL+TSAIE+A++AEE+G+ G +IILSCKVS VQDLIAVYRELARRCDY LHL Sbjct: 187 DARAVMIEALITSAIESARKAEEIGLPGSQIILSCKVSAVQDLIAVYRELARRCDYALHL 246 Query: 241 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLR 300 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPG R KEV+V QEILQTMGLR Sbjct: 247 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGAPREKEVIVAQEILQTMGLR 306 Query: 301 KFTPMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGP 360 FTPMVIACPGCGRTTSTVFQ+LA +IQ++LREQMPVWK +YPGVE MNVAVMGCIVNGP Sbjct: 307 NFTPMVIACPGCGRTTSTVFQELAARIQSYLREQMPVWKTQYPGVEDMNVAVMGCIVNGP 366 Query: 361 GESKHANIGISLPGTGESPAAPVFIDGEKKMTLRGEHIAEEFQKVVLDYVESHYG 415 GESKHANIGISLPGTGESPAAPVF+DG K TLRGE IAE+FQ +V +YV +HYG Sbjct: 367 GESKHANIGISLPGTGESPAAPVFVDGVKVKTLRGERIAEDFQVIVDEYVRTHYG 421 >NMA1524 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis NmA Neisseria meningitidis Z2491 Length = 421 Score = 575 bits (1483), Expect = e-164, Method: Compositional matrix adjust. Identities = 277/406 (68%), Positives = 331/406 (81%), Gaps = 4/406 (0%) Query: 11 LVRRNSRRVVISHGGREIVVGGGAPVMVQSMTNTDTADAIGTAIQIKDLARAGSEVVRLT 70 L RR + +V I H I VG APV++QSMTNTDTADA TA+QIK+L+ AGSE+VR+T Sbjct: 4 LQRRKTHQVRIDH----ITVGSEAPVVIQSMTNTDTADAKATALQIKELSDAGSEMVRIT 59 Query: 71 VNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTEYPECAQALSKYRINPGNVGK 130 VN+PEAA+ V IR +LD MG PL+GDFH+NG LL E+PEC +ALSKYRINPGNVGK Sbjct: 60 VNSPEAASKVAEIRRRLDDMGYATPLIGDFHFNGERLLAEFPECGKALSKYRINPGNVGK 119 Query: 131 GAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENADRAEPWSAQAVMYEAL 190 G K D +FA MI A + DK VRIGVNWGSLDQ+L R+MD N + P + V EAL Sbjct: 120 GVKGDEKFAFMIRTAAENDKAVRIGVNWGSLDQSLAKRMMDANLASSAPKPPEEVTKEAL 179 Query: 191 VTSAIENAQRAEELGMAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLTEAGMGSK 250 + SA+E+A++A LG+ DKIILSCKVS VQDLI VYREL RC YPLHLGLTEAGMGSK Sbjct: 180 IVSALESAEKAVLLGLPEDKIILSCKVSAVQDLIQVYRELGSRCAYPLHLGLTEAGMGSK 239 Query: 251 GIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLRKFTPMVIACP 310 GIVASTAALSVLLQEGIGDTIRISLTPEPG RT+EVVVGQEILQTMGLR FTPMV ACP Sbjct: 240 GIVASTAALSVLLQEGIGDTIRISLTPEPGSPRTQEVVVGQEILQTMGLRSFTPMVTACP 299 Query: 311 GCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGPGESKHANIGI 370 GCGRTTSTVFQ+LA +Q +LR++M +W+ YPGVE++NVAVMGC+VNGPGESK A+IGI Sbjct: 300 GCGRTTSTVFQELAQDVQNYLRQKMSIWRTLYPGVESLNVAVMGCVVNGPGESKLADIGI 359 Query: 371 SLPGTGESPAAPVFIDGEKKMTLRGEHIAEEFQKVVLDYVESHYGQ 416 SLPGTGE+P APV++DGE+K+TL+G++IA EF +V +YV+++YG+ Sbjct: 360 SLPGTGETPVAPVYVDGERKVTLKGDNIATEFLAIVEEYVKTNYGE 405 >NMB1310 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Nme Neisseria meningitidis MC58 Length = 421 Score = 575 bits (1481), Expect = e-164, Method: Compositional matrix adjust. Identities = 277/406 (68%), Positives = 331/406 (81%), Gaps = 4/406 (0%) Query: 11 LVRRNSRRVVISHGGREIVVGGGAPVMVQSMTNTDTADAIGTAIQIKDLARAGSEVVRLT 70 L RR + +V I H I VG APV++QSMTNTDTADA TA+QIK+L+ AGSE+VR+T Sbjct: 4 LQRRKTHQVRIDH----ITVGSEAPVVIQSMTNTDTADAKATALQIKELSDAGSEMVRIT 59 Query: 71 VNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTEYPECAQALSKYRINPGNVGK 130 VN+PEAA+ V IR +LD MG PL+GDFH+NG LL E+PEC +ALSKYRINPGNVGK Sbjct: 60 VNSPEAASKVAEIRRRLDDMGYATPLIGDFHFNGERLLAEFPECGKALSKYRINPGNVGK 119 Query: 131 GAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENADRAEPWSAQAVMYEAL 190 G K D +FA MI A + DK VRIGVNWGSLDQ+L R+MD N + P + V EAL Sbjct: 120 GVKGDEKFAFMIRTAAENDKAVRIGVNWGSLDQSLAKRMMDANLASSAPKPPEEVTKEAL 179 Query: 191 VTSAIENAQRAEELGMAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLTEAGMGSK 250 + SA+E+A++A LG+ DKIILSCKVS VQDLI VYREL RC YPLHLGLTEAGMGSK Sbjct: 180 IVSALESAEKAVLLGLPEDKIILSCKVSAVQDLIQVYRELGSRCAYPLHLGLTEAGMGSK 239 Query: 251 GIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLRKFTPMVIACP 310 GIVASTAALSVLLQEGIGDTIRISLTPEPG RT+EVVVGQEILQTMGLR FTPMV ACP Sbjct: 240 GIVASTAALSVLLQEGIGDTIRISLTPEPGSPRTQEVVVGQEILQTMGLRSFTPMVTACP 299 Query: 311 GCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGPGESKHANIGI 370 GCGRTTSTVFQ+LA +Q +LR++M +W+ YPGVE++NVAVMGC+VNGPGESK A+IGI Sbjct: 300 GCGRTTSTVFQELAQDVQNYLRQKMSIWRTLYPGVESLNVAVMGCVVNGPGESKLADIGI 359 Query: 371 SLPGTGESPAAPVFIDGEKKMTLRGEHIAEEFQKVVLDYVESHYGQ 416 SLPGTGE+P APV++DGE+K+TL+G++IA EF +V +YV+++YG+ Sbjct: 360 SLPGTGETPVAPVYVDGERKVTLKGDNIATEFLAIVEEYVKTNYGE 405 >XF2575 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Xfa Xylella fastidiosa 9a5c Length = 417 Score = 561 bits (1445), Expect = e-159, Method: Compositional matrix adjust. Identities = 267/407 (65%), Positives = 324/407 (79%), Gaps = 4/407 (0%) Query: 10 PLVRRNSRRVVISHGGREIVVGGGAPVMVQSMTNTDTADAIGTAIQIKDLARAGSEVVRL 69 P RR ++ V I H + VGGG PV+VQSMTNTDTAD + + Q+ +L RAGSE+VRL Sbjct: 12 PWPRRRTQAVNIGH----VTVGGGHPVVVQSMTNTDTADVVASTKQVAELWRAGSEMVRL 67 Query: 70 TVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTEYPECAQALSKYRINPGNVG 129 TVN ++AAA+P I E+L MG+DVPL+GDFHYNGH LL + P CA+ L+KYRINPGNVG Sbjct: 68 TVNNAQSAAAIPRIAERLAMMGIDVPLIGDFHYNGHQLLADEPACAEVLAKYRINPGNVG 127 Query: 130 KGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENADRAEPWSAQAVMYEA 189 G KRD QF Q+IE A +Y KP+RIG NWGSLDQ L A++MDEN R +PW A V+ E Sbjct: 128 FGKKRDLQFGQLIECAIRYGKPIRIGANWGSLDQMLAAQLMDENNRRKQPWDAAQVLREV 187 Query: 190 LVTSAIENAQRAEELGMAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLTEAGMGS 249 L+ SA+ +A+RA ELG+ D+I+LS KVSGVQ+LIAVYR++A RCD+ LHLGLTEAG+GS Sbjct: 188 LICSAVGSAERAVELGLPRDRIVLSAKVSGVQELIAVYRDMAARCDFALHLGLTEAGIGS 247 Query: 250 KGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLRKFTPMVIAC 309 KGIVAS+AAL+VLLQEGIGDTIRISLTPEPG RT+EV+V QE+LQT G R FTPMV AC Sbjct: 248 KGIVASSAALAVLLQEGIGDTIRISLTPEPGQSRTQEVIVAQELLQTTGHRAFTPMVTAC 307 Query: 310 PGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGPGESKHANIG 369 PGCGRTTS FQ+LA +Q +R++M VWK +PG E M +AVMGC+VNGPGES+HANIG Sbjct: 308 PGCGRTTSEFFQELAKTVQQHVRDKMQVWKITHPGAETMTLAVMGCVVNGPGESRHANIG 367 Query: 370 ISLPGTGESPAAPVFIDGEKKMTLRGEHIAEEFQKVVLDYVESHYGQ 416 ISLPGTGE P APVFIDGEK +TLRGE+IA++F +V DYVE Y + Sbjct: 368 ISLPGTGEMPVAPVFIDGEKSVTLRGENIAQDFIALVDDYVERRYAR 414 >BMEI0269 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Bme Brucella melitensis Length = 437 Score = 556 bits (1432), Expect = e-158, Method: Compositional matrix adjust. Identities = 266/384 (69%), Positives = 318/384 (82%) Query: 34 APVMVQSMTNTDTADAIGTAIQIKDLARAGSEVVRLTVNTPEAAAAVPAIREQLDRMGVD 93 APV+VQSMTNTDTAD T Q+ L RAGSE+VR+TV+ E+AAAVP IRE+L+R+G D Sbjct: 49 APVVVQSMTNTDTADVDSTVAQVAALHRAGSEIVRITVDRDESAAAVPKIRERLERLGHD 108 Query: 94 VPLVGDFHYNGHTLLTEYPECAQALSKYRINPGNVGKGAKRDTQFAQMIEVACKYDKPVR 153 VPLVGDFHY GH LL ++P CA+AL+KYRINPGNVG K+D QFA ++E+A +YDKPVR Sbjct: 109 VPLVGDFHYIGHKLLADHPACAEALAKYRINPGNVGFKDKKDKQFADIVEMAIRYDKPVR 168 Query: 154 IGVNWGSLDQALLARIMDENADRAEPWSAQAVMYEALVTSAIENAQRAEELGMAGDKIIL 213 IGVNWGSLDQ LL +MD N P SAQ VM EA+V SA+ +A AEE+G+ DKIIL Sbjct: 169 IGVNWGSLDQELLTTLMDRNQAEGAPLSAQDVMREAIVQSALISANLAEEIGLGRDKIIL 228 Query: 214 SCKVSGVQDLIAVYRELARRCDYPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRI 273 S KVS VQDLIAVY LA+R ++ LHLGLTEAGMG+KGIVAS+AA+ +LLQ+GIGDTIRI Sbjct: 229 SAKVSQVQDLIAVYTMLAQRSNHALHLGLTEAGMGTKGIVASSAAMGILLQQGIGDTIRI 288 Query: 274 SLTPEPGGDRTKEVVVGQEILQTMGLRKFTPMVIACPGCGRTTSTVFQDLADKIQTFLRE 333 SLTPEPGGDRT+EV V QE+LQTMG R+F P+V ACPGCGRTTSTVFQ+LA IQ +R Sbjct: 289 SLTPEPGGDRTREVQVAQELLQTMGFRQFVPIVAACPGCGRTTSTVFQELAQTIQEDIRR 348 Query: 334 QMPVWKGKYPGVEAMNVAVMGCIVNGPGESKHANIGISLPGTGESPAAPVFIDGEKKMTL 393 MP+W+ KYPGVEA++VAVMGCIVNGPGESKHA+IGISLPGTGE+P+APVF+DG+K TL Sbjct: 349 NMPLWREKYPGVEALSVAVMGCIVNGPGESKHADIGISLPGTGETPSAPVFVDGKKVTTL 408 Query: 394 RGEHIAEEFQKVVLDYVESHYGQG 417 RG IAE+FQK+V DY+E+ +G G Sbjct: 409 RGPGIAEDFQKMVADYIENRFGLG 432