BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0009.p (297 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1223 [O] COG0330 Membrane protease subunits, stomatin/prohibi... 362 e-100 PA4941 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 231 2e-60 HI0150 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 211 2e-54 PM0118 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 208 1e-53 VC0350 [O] COG0330 Membrane protease subunits, stomatin/prohibit... 196 6e-50 >RSc1223 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Rso Ralstonia solanacearum Length = 304 Score = 362 bits (930), Expect = e-100, Method: Compositional matrix adjust. Identities = 167/295 (56%), Positives = 227/295 (76%) Query: 1 MGRLVTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEVKQVITEPGLHFKLPPPFQNVM 60 M RL+++++ V+A+ + SS +FVVDQR A+VFA GE+KQVI EPGLHFKLPPP QNV+ Sbjct: 1 MNRLISALVALVIALAVLSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVI 60 Query: 61 YLDKRIQTLDTPDADRFITAEKMNVLVDAYVKWRIVDPRLYFVSFGADERRTQDRLSQIV 120 ++DKR+ T+D ADRFITAEK N+LVD +VKWR+ DPRL++VSF D R QD ++Q + Sbjct: 61 FMDKRLMTIDVAGADRFITAEKKNLLVDWFVKWRVSDPRLFYVSFKGDNRLAQDSMTQKI 120 Query: 121 KAALNDEITKRTVREVISSQRNNVMDAIQARVANEAKQIGVEVIDVRLRRVDYVDQINNS 180 + DE +RTV +V+S+ R VM +I V + +GV++IDVRL+RVD + + S Sbjct: 121 NSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGRSVGVDIIDVRLKRVDLLASVTES 180 Query: 181 VFERMKSERVRVANELRSTGAAESEKIRADADRQRVVILAEAYRESEKIRGAGDSKASQI 240 V+ RM++ER RVANELRSTGAAE EKIRADADRQR V+LA+AYRE++KI+G GD++A+ I Sbjct: 181 VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYREAQKIKGEGDARAADI 240 Query: 241 YAQAFGQNPEFFKFYRSLEAYRASFKNRHDVMVVDPSSEFFKYFKGIGAGSASTS 295 YA AFG++P+F F+RS+EAYRASF++R DVMV+ P S+FFK+ +G G S + Sbjct: 241 YADAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPGSDFFKFMRGPNGGGQSVA 295 >PA4941 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Pae Pseudomonas aeruginosa Length = 289 Score = 231 bits (588), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 136/281 (48%), Positives = 192/281 (68%), Gaps = 3/281 (1%) Query: 5 VTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEVKQVITEPGLHFKLPPPFQNVMYLDK 64 + ++IV VVA + ++++VV Q A++ G V + +PGLHFK+P Q V D Sbjct: 6 LIALIVGVVAAIVLWNSVYVVQQTERAVMLRFGRVVESDVKPGLHFKIPYVNQ-VRKFDA 64 Query: 65 RIQTLDTPDADRFITAEKMNVLVDAYVKWRIVDPRLYFVSFGADERRTQDRLSQIVKAAL 124 R+ TLD P RF+T EK V+VDAY KWR+ D ++ + ++ +RLS+ ++A L Sbjct: 65 RLLTLDAP-TQRFLTLEKKAVMVDAYAKWRVADAERFYTATSGLKQIADERLSRRLEAGL 123 Query: 125 NDEITKRTVREVISSQRNNVMDAIQARVANEA-KQIGVEVIDVRLRRVDYVDQINNSVFE 183 D+ KRT+ EV+S +R+ +M I A + A K++G+EVIDVR++ +D ++N SVFE Sbjct: 124 RDQFGKRTLHEVVSGERDALMGDITASLNRMAQKELGIEVIDVRVKAIDLPKEVNRSVFE 183 Query: 184 RMKSERVRVANELRSTGAAESEKIRADADRQRVVILAEAYRESEKIRGAGDSKASQIYAQ 243 RM +ER R A E R+ G +E IRADADRQR VI+AEAYRESE+ RG GDSKA+ IYA+ Sbjct: 184 RMSTEREREAREHRAKGRELAEGIRADADRQRRVIVAEAYRESEETRGDGDSKAAAIYAK 243 Query: 244 AFGQNPEFFKFYRSLEAYRASFKNRHDVMVVDPSSEFFKYF 284 A+ Q+PEF+ FYRSL+AYR SF + DV+V+DPSSEFF+Y Sbjct: 244 AYNQDPEFYSFYRSLKAYRESFAEKRDVLVLDPSSEFFRYL 284 >HI0150 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Hin Haemophilus influenzae Length = 295 Score = 211 bits (536), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 113/295 (38%), Positives = 189/295 (64%), Gaps = 14/295 (4%) Query: 1 MGRLVTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEV------KQVITEPGLHFKLPP 54 M R + VI + A+ S+I VV + + I+ +V K V+ EPGLHFK+P Sbjct: 1 MRRFLLPVIFVIAAV--VYSSIVVVTEGTRGIMLRFNKVQRDADNKVVVYEPGLHFKVPL 58 Query: 55 PFQNVMYLDKRIQTLDTPDADRFITAEKMNVLVDAYVKWRIVD-PRLYFVSFGADERRTQ 113 ++ LD RI+TLD A RF+T EK ++LVD+YVKW+I D R Y + G D + Sbjct: 59 -IDSIKVLDARIRTLDGS-ATRFVTVEKKDLLVDSYVKWKISDFGRFYTSTGGGDYAQAA 116 Query: 114 DRLSQIVKAALNDEITKRTVREVISSQRNNVMDAIQARVA---NEAKQIGVEVIDVRLRR 170 + LS+ V L EI RT+++++S R +M+ + ++ + ++G+EVIDVR+++ Sbjct: 117 NLLSRKVNDRLRSEIGSRTIKDIVSGTRGELMEGAKKALSSGQDSTAELGIEVIDVRVKQ 176 Query: 171 VDYVDQINNSVFERMKSERVRVANELRSTGAAESEKIRADADRQRVVILAEAYRESEKIR 230 ++ D++++S+++RM++ER VA E RS G ++ I+AD DR+ +ILA A + ++++R Sbjct: 177 INLPDEVSSSIYQRMRAERDAVAREHRSQGKEKAAFIQADVDRKVTLILANANKTAQELR 236 Query: 231 GAGDSKASQIYAQAFGQNPEFFKFYRSLEAYRASFKNRHDVMVVDPSSEFFKYFK 285 G+GD+ A+++Y+ AF Q P+FF F RSL+AY ASF N ++M++ P S+FF++ + Sbjct: 237 GSGDAAAAKLYSDAFAQEPQFFTFVRSLKAYEASFANSDNIMILKPDSDFFRFMQ 291 >PM0118 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Pmu Pasteurella multocida Length = 295 Score = 208 bits (529), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 110/295 (37%), Positives = 188/295 (63%), Gaps = 14/295 (4%) Query: 1 MGRLVTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEV------KQVITEPGLHFKLPP 54 M + +T VIV + AI S+I +V + + I+ +V K V+ PGLHFK+P Sbjct: 1 MRKFLTPVIVVIAAILY--SSIVIVSEGTRGIMLRFSKVHRDADNKVVVYNPGLHFKIPF 58 Query: 55 PFQNVMYLDKRIQTLDTPDADRFITAEKMNVLVDAYVKWRIVD-PRLYFVSFGADERRTQ 113 ++ LD RI+TLD ADRF+T EK ++LVD+YVKWRI D R Y + G D + Sbjct: 59 -IDSIKILDARIRTLDG-QADRFVTVEKKDLLVDSYVKWRISDFGRFYTATGGGDYAQAS 116 Query: 114 DRLSQIVKAALNDEITKRTVREVISSQRNNVMDAIQARV---ANEAKQIGVEVIDVRLRR 170 + L + V L E RT+++++S R +M+ + + + ++G+EV+DVR+++ Sbjct: 117 NLLRRKVNDRLRSETGSRTIKDIVSGTRGELMEGARKALNTGPDSTAELGIEVVDVRVKQ 176 Query: 171 VDYVDQINNSVFERMKSERVRVANELRSTGAAESEKIRADADRQRVVILAEAYRESEKIR 230 ++ D++++S+++RM++ER VA E RS G ++ I+AD DR+ +ILA A R ++++R Sbjct: 177 INLPDEVSSSIYQRMRAERDAVAREHRSQGREKAAFIQADVDRKVTLILANANRTAQELR 236 Query: 231 GAGDSKASQIYAQAFGQNPEFFKFYRSLEAYRASFKNRHDVMVVDPSSEFFKYFK 285 G+GD+ A+++++ AF Q P+F+ F RSL+AY +SF N ++M++ P S+FF++ + Sbjct: 237 GSGDATAAKVFSDAFSQEPQFYSFLRSLKAYESSFANSDNMMILKPDSDFFRFMQ 291 >VC0350 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Vch Vibrio cholerae Length = 326 Score = 196 bits (498), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 119/329 (36%), Positives = 185/329 (56%), Gaps = 41/329 (12%) Query: 1 MGRLVTSVIVAVVAIWLASSTIFVVDQRSSAIVFALGEVKQ------VITEPGLHFKLPP 54 M +L+ IV ++A L S +FV+ + IV G V + I EPGLHFK+P Sbjct: 1 MRKLLIPSIVLIIAALLMS--MFVIPEGERGIVIRFGRVLKDNNDLARIYEPGLHFKMPL 58 Query: 55 PFQNVMYLDKRIQTLDTPDADRFITAEKMNVLVDAYVKWRIVDPRLYFVSFGADERRTQD 114 F V LD RIQT+D +DRF+T+EK +V++D YVKWRI D Y+++ G T + Sbjct: 59 -FDRVKTLDARIQTMDGR-SDRFVTSEKKDVIIDTYVKWRIEDFGQYYLATGGGNALTAE 116 Query: 115 RL-SQIVKAALNDEITKRTVREVISSQRNNVM-------------------------DAI 148 L + V L EI R +++++S RN + D I Sbjct: 117 ALLERKVTDVLRSEIGAREIKQIVSGPRNVAVLPENADSSELTTEAAKEAMEIDGQRDQI 176 Query: 149 QARVANEA-----KQIGVEVIDVRLRRVDYVDQINNSVFERMKSERVRVANELRSTGAAE 203 + V N+ K +GV V+D R+++++ D+I+ S++ RM++ER VA + RS G + Sbjct: 177 MSEVLNDTRESAMKDLGVYVVDFRMKKINLPDEISESIYRRMRAERESVARKHRSQGREK 236 Query: 204 SEKIRADADRQRVVILAEAYRESEKIRGAGDSKASQIYAQAFGQNPEFFKFYRSLEAYRA 263 +E IRA A+ + ILAEA + + RG D++A++IY+ A+ ++PEFF F RSL AY Sbjct: 237 AEVIRAQAELEVATILAEADKTARVTRGTADAEAAKIYSDAYKKDPEFFSFLRSLRAYEK 296 Query: 264 SFKNRHDVMVVDPSSEFFKYFKGIGAGSA 292 SF +++D++V+DP+SEFF+Y +A Sbjct: 297 SFNSKNDILVLDPNSEFFQYMNNAKGAAA 325