BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0004.p (1531 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2402_1 [Q] COG1020 Non-ribosomal peptide synthetase modules an... 735 0.0 PA2402_3 [Q] COG1020 Non-ribosomal peptide synthetase modules an... 706 0.0 all2648_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 689 0.0 all2643 [Q] COG1020 Non-ribosomal peptide synthetase modules and... 672 0.0 PA2402_4 [Q] COG1020 Non-ribosomal peptide synthetase modules an... 662 0.0 >PA2402_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Pae Pseudomonas aeruginosa Length = 1541 Score = 735 bits (1897), Expect = 0.0, Method: Compositional matrix adjust. Identities = 500/1215 (41%), Positives = 676/1215 (55%), Gaps = 96/1215 (7%) Query: 1 LQGRDQEATRRFWEIQLARLQQPTRLADAMPRPSTPQSGHGEHRELLDATLTARLNEAAR 60 L+ +QE +W +L L PRP+ P + ++ L L AR Sbjct: 231 LEAGEQERQLEYWRGKLGERHPVLELPTDHPRPAVPSYRGSRYEFSIEPALAEALRGTAR 290 Query: 61 AQRITLNTLVQAAWALLLQRYTYAAHDQGVVFGATVAGRPAELTGVEQLLGLFINTLPVI 120 Q +TL L+ + +LLQRY+ + G +A R VE L+GLF+NT + Sbjct: 291 RQGLTLFMLLLGGFNILLQRYS---GQTDLRVGVPIANR--NRAEVEGLIGLFVNTQVLR 345 Query: 121 VATPPHQPAGDWMRALQAQNLQAREYEHTP---LVDIQRWSGQGAQA-LFDSILVFENYP 176 + L+ L A+ ++ P LV+ + + + LF +++ + P Sbjct: 346 SVFDGRTSVATLLAGLKDTVLGAQAHQDLPFERLVEAFKVERSLSHSPLFQ--VMYNHQP 403 Query: 177 VDATLSQ-GAPAGLAFSSVRHREETN-YPMTV-VVNAGDTLQLQLRYARAQFAHEMVERI 233 + A + + AGL+F + + T + +++ G L L YA F VER+ Sbjct: 404 LVADIEALDSVAGLSFGQLDWKSRTTQFDLSLDTYEKGGRLYAALTYATDLFEARTVERM 463 Query: 234 GAHLRHLLQVLAEHPQQAIGSLGLLPGDE----LAAWRESGVNRELHAFDAPVHRLIERQ 289 H ++LL+ + E+PQ ++ SL +L +E L W + + VHRL E Q Sbjct: 464 ARHWQNLLRGMLENPQASVDSLPMLDAEERGQLLEGWNATAAE---YPLQRGVHRLFEEQ 520 Query: 290 AAATPSAAALLYEDLVLDYRSLNQQANRLAHRLLAEGAGPERIVGVAARRAPEMVVALLA 349 TP+A AL + + LDY LN++ANRLAH L+ G G +R+VGVA R+ EMVVAL+A Sbjct: 521 VERTPTAPALAFGEERLDYAELNRRANRLAHALIERGVGADRLVGVAMERSIEMVVALMA 580 Query: 350 VLKAGAAYLPLDPDLPPARLADMMADSGLSLLLTQTALRAELTAPAAVRVLELDAPGQPW 409 +LKAG AY+P+DP+ P R A M+ DSG+ LLL+Q+ L+ L V+ ++LD W Sbjct: 581 ILKAGGAYVPVDPEYPEERQAYMLEDSGVQLLLSQSHLKLPLAQ--GVQRIDLDQ-ADAW 637 Query: 410 AEGMPDHDPGIEVAPDGLAYVIYTSGSTGKPKGAGNRHVSLHNRLAWMQEAYPIGPGNTV 469 E +++PG+E+ + LAYVIYTSGSTGKPKGAGNRH +L NRL WMQ+AY +G G+TV Sbjct: 638 LENHAENNPGVELNGENLAYVIYTSGSTGKPKGAGNRHSALSNRLCWMQQAYGLGVGDTV 697 Query: 470 LQKTPFGFDVSVWEFFWPLMTGARLALAAPDEHRDPALLAARIRRHAVDTLHFVPSMLQA 529 LQKTPF FDVSVWEFFWPLM+GARL +AAP +HRDPA L I R VDTLHFVPSMLQA Sbjct: 698 LQKTPFSFDVSVWEFFWPLMSGARLVVAAPGDHRDPAKLVELINREGVDTLHFVPSMLQA 757 Query: 530 FVAHPDSAQCHSLRQVICSGEALPAELQEQAFARLPQIALHNLYGPTEAAIDVTHWTC-R 588 F+ D A C SL++++CSGEALPA+ Q+Q FA+LPQ L+NLYGPTEAAIDVTHWTC Sbjct: 758 FLQDEDVASCTSLKRIVCSGEALPADAQQQVFAKLPQAGLYNLYGPTEAAIDVTHWTCVE 817 Query: 589 PGERSVPIGRPISHTAAYVLDGGLNPLPHGIAGELYLGGIGLARGYLGRPGLSAERFVAD 648 G+ +VPIGRPI++ A Y+LDG L P+P G+ GELYL G GLARGY RPGL+AERFVA Sbjct: 818 EGKDAVPIGRPIANLACYILDGNLEPVPVGVLGELYLAGRGLARGYHQRPGLTAERFVAS 877 Query: 649 PFAADGSRMYRTGDLVRRRADGEIEYLGRTDHQVKIRGLRIELGEIEAQLLAQPGVAAAV 708 PF A G RMYRTGDL R RADG IEY GR DHQVK+RGLRIELGEIEA+LL P V A Sbjct: 878 PFVA-GERMYRTGDLARYRADGVIEYAGRIDHQVKLRGLRIELGEIEARLLEHPWVREAA 936 Query: 709 VVALVEPGRPARLVGYAA-DPGGMLEAEALRAALLQSLPDYMVPQRLILLPALPLNANGK 767 V+A+ G+ +LVGY + G EAL A L SLP+YMVP + + L +PL+ NGK Sbjct: 937 VLAV--DGK--QLVGYVVLESEGGDWREALAAHLATSLPEYMVPAQWLALERMPLSPNGK 992 Query: 768 VDRKALPRPDFN-EQGGYEAPQGQTEIGLAAIWAEVLRLQRVGRHDNFFELGGDSILSLQ 826 +DRKALP P+ + Q GY AP+ E LA IW ++L +++VG DNFF LGGDSI+S+Q Sbjct: 993 LDRKALPAPEVSVAQAGYSAPRNAVERTLAEIWQDLLGVEQVGLDDNFFSLGGDSIVSIQ 1052 Query: 827 IVARAHEQGWPLTPRQLFQSQTVAELAQQCDQLQPPAPAQAVTAARGRLEDYLSAAQTAQ 886 +V+RA + G L+PR LFQ Q + LA +A A Sbjct: 1053 VVSRARQAGLQLSPRDLFQHQNIRSLAL-------------------------AAKAGAA 1087 Query: 887 LALQGELEDVYPLSPMQQGMLFHTMESPGSGLYVNQLSVRV-EGLDEARFAQAWQSVLAR 945 A QG L+P+Q+ F P + L ++ + LD R +A + + A+ Sbjct: 1088 TAEQGPASGEVALAPVQR--WFFEQSIPNRQHWNQSLLLQARQPLDGDRLGRALERLQAQ 1145 Query: 946 HPVMRTGF-----LWQAGYA-QPLQAVWRTLAFGIEVQDWSARADDAELPQAIAAFAAAD 999 H +R F W YA Q + +WR A EV A ++A+ Sbjct: 1146 HDALRLRFREERGAWHQAYAEQAGEPLWRRQAGSEEV--LLALCEEAQ------------ 1191 Query: 1000 LARGFDLLQPPLVRATLLRLGPGQHQLVWTMHHILLDGWSTSALMQELMLAYGGQPLPAP 1059 R DL Q PL+RA L+ + G +L+ +HH+ +DG S L+++L Y L A Sbjct: 1192 --RSLDLEQGPLLRALLVDMADGSQRLLLVIHHLAVDGVSWRILLEDLQRLYAD--LDAD 1247 Query: 1060 -GPDYAQYIGWLATLDPQAAQR-----YWMGALQALDGPSLL-AEGVRPDPARRGFGKLY 1112 GP + Y W L QA R YW L D P L E R KL Sbjct: 1248 LGPRSSSYQAWSRHLHEQAGARLDELDYWQAQLH--DAPHALPCENPHGALENRHERKLV 1305 Query: 1113 GHCDAAATRRLEQFA-RSQRVTLNTLVQGAWSLALARHKRSTAVAFGATVSGRPAALPGV 1171 DA TR+L Q A + R +N L+ A + A R +V GR + Sbjct: 1306 LTLDAERTRQLLQEAPAAYRTQVNDLLLTALARATCRWSGDASVLVQLEGHGREDLGEAI 1365 Query: 1172 E--KSLGLFINTIPI 1184 + +++G F + P+ Sbjct: 1366 DLSRTVGWFTSLFPL 1380 Score = 109 bits (272), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 116/386 (30%), Positives = 176/386 (45%), Gaps = 44/386 (11%) Query: 899 LSPMQQGMLFHTMESPGSGLYVNQLSVRVEG-LDEARFAQAWQSVLARHPVMRTGF---- 953 LS QQ M F P SG Y +VR+ G LD +A+ S++ RH +RT F Sbjct: 52 LSYAQQRMWFLWHLEPQSGAYNLPSAVRLNGPLDRQALERAFASLVQRHETLRTVFPRGA 111 Query: 954 ---LWQAGYAQPLQAVWRTLAFGIEVQDWSARADDAELPQAIAAFAAADLARGFDLLQPP 1010 L QA +PL+ + +D S +D E + A + + FDL + P Sbjct: 112 DDSLAQAPLQRPLE---------VAFEDCSGLPED-EQEARLREEAQRESLQPFDLCEGP 161 Query: 1011 LVRATLLRLGPGQHQLVWTMHHILLDGWSTSALMQELMLAY-----GGQP-LPAPGPDYA 1064 L+R L+RLG +H L+ T+HHI+ DGWS + L++E Y G +P LPA YA Sbjct: 162 LLRVRLIRLGEERHVLLLTLHHIVSDGWSMNVLIEEFSRFYSAYATGAEPGLPALPIQYA 221 Query: 1065 QYI----GWLATLDPQAAQRYWMGALQALDGPSLLAEGVRPDPARRGF-GKLYGH-CDAA 1118 Y WL + + YW G L P L P PA + G Y + A Sbjct: 222 DYALWQRSWLEAGEQERQLEYWRGKL-GERHPVLELPTDHPRPAVPSYRGSRYEFSIEPA 280 Query: 1119 ATRRLEQFARSQRVTLNTLVQGAWSLALARHKRSTAVAFGATVSGRPAALPGVEKSLGLF 1178 L AR Q +TL L+ G +++ L R+ T + G ++ R A VE +GLF Sbjct: 281 LAEALRGTARRQGLTLFMLLLGGFNILLQRYSGQTDLRVGVPIANRNRA--EVEGLIGLF 338 Query: 1179 INTIPIVVEVDGQRRVGDWLRTLQQTNIDSREHEHTPL------YDIQRWSGMAGRALFD 1232 +NT + DG+ V L L+ T + ++ H+ P + ++R ++ LF Sbjct: 339 VNTQVLRSVFDGRTSVATLLAGLKDTVLGAQAHQDLPFERLVEAFKVER--SLSHSPLFQ 396 Query: 1233 SIIVFENFPISRSLEA-RAQAGLXAG 1257 +++ + P+ +EA + AGL G Sbjct: 397 --VMYNHQPLVADIEALDSVAGLSFG 420 >PA2402_3 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Pae Pseudomonas aeruginosa Length = 1495 Score = 706 bits (1823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/1077 (42%), Positives = 614/1077 (57%), Gaps = 115/1077 (10%) Query: 12 FWEIQLARLQQPTRLADAMPRPSTPQSGHGEHREL-LDATLTARLNEAARAQRITLNTLV 70 +W +L Q L RP+ SG G+ ++ L +L+ L AR + +T L+ Sbjct: 192 YWRERLGAEQPVLELPADRVRPAQA-SGRGQRLDMALPVSLSEELLACARREGVTPFMLL 250 Query: 71 QAAWALLLQRYTYAAHDQGVVFGATVAGRPAELTGVEQLLGLFINTLPV----------- 119 A++ +LL+RY+ + + G +A R VE+L+G F+NT + Sbjct: 251 LASFQVLLKRYSGQSD---IRVGVPIANR--NRAEVERLIGFFVNTQVLRCQVDAGLAFR 305 Query: 120 ---------IVATPPHQ--PAGDWMRALQAQNLQAREYEHTPLVDI--QRWSGQGAQALF 166 + HQ P + ALQ + R H+PL + SG+ A Sbjct: 306 DLLGRVREAALGAQAHQDLPFEQLVDALQPE----RNLSHSPLFQVMYNHQSGERQDAQV 361 Query: 167 DSILVFENYPVDATLSQGAPAGLAFSSVRHREETNYPMTVVVNAGDTLQLQLRYARAQFA 226 D + + E++ D +Q F ET D L L YA F Sbjct: 362 DGLHI-ESFAWDGAAAQ-------FDLALDTWETP----------DGLGAALTYATDLFE 403 Query: 227 HEMVERIGAHLRHLLQVLAEHPQQAIGSLGLLPGDE----LAAWRESGVNRELHAFDAPV 282 VER+ H ++LL+ + E+PQ ++ SL +L +E L W + + V Sbjct: 404 ARTVERMARHWQNLLRGMLENPQASVDSLPMLDAEERGQLLEGWNATAAE---YPLQRGV 460 Query: 283 HRLIERQAAATPSAAALLYEDLVLDYRSLNQQANRLAHRLLAEGAGPERIVGVAARRAPE 342 HRL E Q TP+A AL + + LDY LN++ANRLAH L+ G G +R+VGVA R+ E Sbjct: 461 HRLFEEQVERTPTAPALAFGEERLDYAELNRRANRLAHALIERGVGADRLVGVAMERSIE 520 Query: 343 MVVALLAVLKAGAAYLPLDPDLPPARLADMMADSGLSLLLTQTALRAELTAPAAVRVLEL 402 MVVAL+A+LKAG AY+P+DP+ P R A M+ DSG+ LLL+Q+ L+ L V+ ++L Sbjct: 521 MVVALMAILKAGGAYVPVDPEYPEERQAYMLEDSGVQLLLSQSHLKLPLAQ--GVQRIDL 578 Query: 403 DAPGQPWAEGMPDHDPGIEVAPDGLAYVIYTSGSTGKPKGAGNRHVSLHNRLAWMQEAYP 462 D W E +++PGIE+ + LAYVIYTSGSTGKPKGAGNRH +L NRL WMQ+AY Sbjct: 579 DQ-ADAWLENHAENNPGIELNGENLAYVIYTSGSTGKPKGAGNRHSALSNRLCWMQQAYG 637 Query: 463 IGPGNTVLQKTPFGFDVSVWEFFWPLMTGARLALAAPDEHRDPALLAARIRRHAVDTLHF 522 +G G+TVLQKTPF FDVSVWEFFWPLM+GARL +AAP +HRDPA L A I R VDTLHF Sbjct: 638 LGVGDTVLQKTPFSFDVSVWEFFWPLMSGARLVVAAPGDHRDPAKLVALINREGVDTLHF 697 Query: 523 VPSMLQAFVAHPDSAQCHSLRQVICSGEALPAELQEQAFARLPQIALHNLYGPTEAAIDV 582 VPSMLQAF+ D C SL++++CSGEAL A+ Q+Q FA+LPQ L+NLYGPTEAAIDV Sbjct: 698 VPSMLQAFLQDEDVVSCTSLKRIVCSGEALSADAQQQVFAKLPQAGLYNLYGPTEAAIDV 757 Query: 583 THWTC-RPGERSVPIGRPISHTAAYVLDGGLNPLPHGIAGELYLGGIGLARGYLGRPGLS 641 THW+C G+ +VPIGRPI++ Y+LDG L P+P G+ GELYL G GLARGY RPGL+ Sbjct: 758 THWSCVEEGKDAVPIGRPIANLGCYILDGDLEPVPVGVLGELYLAGRGLARGYHQRPGLT 817 Query: 642 AERFVADPFAADGSRMYRTGDLVRRRADGEIEYLGRTDHQVKIRGLRIELGEIEAQLLAQ 701 AERFVA PF A G RMYRTGDL R RADG IEY GR DHQVK+RGLRIELGEIEA+LL Sbjct: 818 AERFVASPFVA-GERMYRTGDLARYRADGVIEYAGRIDHQVKLRGLRIELGEIEARLLEH 876 Query: 702 PGVAAAVVVALVEPGRPARLVGYAA-DPGGMLEAEALRAALLQSLPDYMVPQRLILLPAL 760 P V A V+A+ +LVGY + G EAL A L SLP+YMVP + + L + Sbjct: 877 PWVREAAVLAV----DSRQLVGYVVLESEGGDWREALAAHLATSLPEYMVPAQWLALERM 932 Query: 761 PLNANGKVDRKALPRPDFNEQGGYEAPQGQTEIGLAAIWAEVLRLQRVGRHDNFFELGGD 820 PL+ NGK+DRKALPRP + APQ + E +AA+WA+VL+L+ VG DNFF LGGD Sbjct: 933 PLSPNGKLDRKALPRPQAAAGQTHVAPQNEMERRIAAVWADVLKLEEVGATDNFFALGGD 992 Query: 821 SILSLQIVARAHEQGWPLTPRQLFQSQTVAELAQQCDQLQPPAPAQAVTAARGRLEDYLS 880 SI+S+Q+V+R G TP+ LFQ QTV LA R+ + Sbjct: 993 SIVSIQVVSRCRAAGIQFTPKDLFQQQTVQGLA--------------------RVARVGA 1032 Query: 881 AAQTAQLALQGELEDVYPLSPMQQGMLFHTMESPGSGLYVNQLSVR-VEGLDEARFAQAW 939 A Q Q + GE L P Q+ LF P + L ++ E L+ A Sbjct: 1033 AVQMEQGPVSGE----TVLLPFQR--LFFEQPIPNRQHWNQSLLLKPREALNAKALEAAL 1086 Query: 940 QSVLARHPVMRTGF-----LWQAGYAQPLQAVWRTLAFGIEVQDWSARADDAELPQAIAA 994 Q+++ H +R F W A +A+ TL + W A A D + +++ Sbjct: 1087 QALVEHHDALRLRFHETDGTWHAEHAEA------TLGGALL---WRAEAVDRQALESL-- 1135 Query: 995 FAAADLARGFDLLQPPLVRATLLRLGPGQHQLVWTMHHILLDGWSTSALMQELMLAY 1051 + R DL PL+R+ L+ + G +L+ +HH+++DG S L+++L AY Sbjct: 1136 --CEESQRSLDLADGPLLRSLLVDMADGGQRLLLVIHHLVVDGVSWRILLEDLQRAY 1190 Score = 92.4 bits (228), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 106/334 (31%), Positives = 157/334 (47%), Gaps = 27/334 (8%) Query: 898 PLSPMQQGMLFHTMESPGSGLYVNQLSVRVEG-LDEARFAQAWQSVLARHPVMRTGFLWQ 956 PLS QQ M F P S Y + V G LD+A QA+ ++ RH +RT F Sbjct: 5 PLSHAQQRMWFLWKLEPESAAYHLPSVLHVRGVLDQAALQQAFDWLVLRHETLRTRFEEV 64 Query: 957 AGYAQPLQAVWRTLAFGIEVQDWSARADDAELPQAIAAFAAADLARGFDLLQPPLVRATL 1016 G A+ Q + + I ++D A A +A L Q +A ++ + FDL + PL+R L Sbjct: 65 DGQAR--QTILANMPLRIVLED-CAGASEATLRQRVAE----EIRQPFDLARGPLLRVRL 117 Query: 1017 LRLGPGQHQLVWTMHHILLDGWSTSALMQELMLAY-----GGQPLPAP-GPDYAQYIGW- 1069 L L +H LV T HHI+ DGWS ++ EL+ AY G QP AP YA Y W Sbjct: 118 LALAGQEHVLVITQHHIVSDGWSMQVMVDELLQAYAAARRGEQPTLAPLTLQYADYAAWH 177 Query: 1070 LATLDPQAAQR---YW---MGALQ-ALDGPSLLAEGVRPDPARRGFGKLYGHCDAAATRR 1122 A LD R YW +GA Q L+ P A+ VRP A +L + + Sbjct: 178 RAWLDSGEGARQLDYWRERLGAEQPVLELP---ADRVRPAQASGRGQRLDMALPVSLSEE 234 Query: 1123 LEQFARSQRVTLNTLVQGAWSLALARHKRSTAVAFGATVSGRPAALPGVEKSLGLFINTI 1182 L AR + VT L+ ++ + L R+ + + G ++ R A VE+ +G F+NT Sbjct: 235 LLACARREGVTPFMLLLASFQVLLKRYSGQSDIRVGVPIANRNRA--EVERLIGFFVNTQ 292 Query: 1183 PIVVEVDGQRRVGDWLRTLQQTNIDSREHEHTPL 1216 + +VD D L +++ + ++ H+ P Sbjct: 293 VLRCQVDAGLAFRDLLGRVREAALGAQAHQDLPF 326 >all2648_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Nos Nostoc sp. PCC 7120 Length = 1063 Score = 689 bits (1778), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/879 (43%), Positives = 515/879 (58%), Gaps = 45/879 (5%) Query: 1 LQGRDQEATRRFWEIQLARLQQPTRLADAMPRPSTPQSGHGEHRELLDATLTARLNEAAR 60 LQ ++ E FW QL PT L + + QS + +++ T +L R Sbjct: 186 LQQQNPEQAESFWRKQLQDFTAPTVLGNKINN----QSSIFSQQSKVNSQQTEQLQNFVR 241 Query: 61 AQRITLNTLVQAAWALLLQRYTYAAHDQGVVFGATVAGRPAELTGVEQLLGLFINTLPVI 120 R+TLN LVQ AWALLL RY + + V+FG TV+GRP EL VE ++GLFINTLPV Sbjct: 242 QHRLTLNILVQGAWALLLSRY---SGENNVLFGTTVSGRPPELPQVESIVGLFINTLPVR 298 Query: 121 VATPPHQPAGDWMRALQAQNLQAREYEHTPLVDIQRWSGQ-GAQALFDSILVFENYPVDA 179 V W++ LQAQ ++ +Y ++ LVDIQ WS +LF+S+LVFENYPV Sbjct: 299 VDVNGEMQIIPWLQQLQAQQVEREQYSYSSLVDIQSWSSVPRGTSLFESLLVFENYPVSI 358 Query: 180 -TLSQGAPAGLAFSSVRHREETNYPMTVVVNAGDTLQLQLRYARAQFAHEMVERIGAHLR 238 ++ + L + E+TNYP+T+ V G+ L ++ Y + F + R+ HL Sbjct: 359 ESVIKTFDQTLQIEDTQGFEKTNYPLTLTVIPGEELLFKVSYDVSYFDAATISRLLGHLE 418 Query: 239 HLLQVLAEHPQQAIGSLGLLPGDE----LAAWRESGVNRELHAF-DAPVHRLIERQAAAT 293 LL + P+Q + L +L E L W N+ A+ + +H+L E Q T Sbjct: 419 TLLMSMVNEPEQRLSQLSMLTPQEKQLILKDW-----NQTTQAYPNQCIHQLFEAQVERT 473 Query: 294 PSAAALLYEDLVLDYRSLNQQANRLAHRLLAEGAGPERIVGVAARRAPEMVVALLAVLKA 353 P A AL++ + L YR LN +AN+LAH L G PE +VG+ R+ EM V LL ++KA Sbjct: 474 PDAIALVFGEECLTYRELNNKANQLAHYLQQLGVKPEILVGICLERSLEMTVCLLGIIKA 533 Query: 354 GAAYLPLDPDLPPARLADMMADSGLSLLLTQTALRAELTAPAAVRVLELDAPGQPWAEGM 413 G AY+P+DP+ P R+A M+ DS + + LTQ L A++ ++ +D + Sbjct: 534 GGAYVPIDPEYPQERIAYMLEDSQVKVFLTQEQLLAQIPQNQTHKIC-IDTEWDKISR-Q 591 Query: 414 PDHDPGIEVAPDGLAYVIYTSGSTGKPKGAGNRHVSLHNRLAWMQEAYPIGPGNTVLQKT 473 P+ +P V D LAYVIYTSGSTGKPKG N H + NRL WMQE Y I +++LQKT Sbjct: 592 PNTNPDSGVKLDNLAYVIYTSGSTGKPKGVMNTHQGICNRLLWMQETYQINSTDSILQKT 651 Query: 474 PFGFDVSVWEFFWPLMTGARLALAAPDEHRDPALLAARIRRHAVDTLHFVPSMLQAFVAH 533 PF FDVSVWEFFW L+TGARL +A P HRD A L I + + LHFVPSML+ F+ Sbjct: 652 PFSFDVSVWEFFWTLLTGARLVIAKPGGHRDSAYLINLIIQEQITILHFVPSMLRIFLES 711 Query: 534 PDSAQCHSLRQVICSGEALPAELQEQAFARLPQIALHNLYGPTEAAIDVTHWTCRP--GE 591 + +C SL++VICSGEAL +LQ Q R L+NLYGPTEAAIDVT W CR Sbjct: 712 GNVEKCTSLKRVICSGEALSLDLQNQFLERF-DCELYNLYGPTEAAIDVTFWQCRKHTNL 770 Query: 592 RSVPIGRPISHTAAYVLDGGLNPLPHGIAGELYLGGIGLARGYLGRPGLSAERFVADPFA 651 ++VPIGRPI++T Y+LD L P+P G+ GELY+GG G+ARGYL RP L+AERF++ ++ Sbjct: 771 KTVPIGRPIANTHIYILDQHLQPVPIGVPGELYIGGAGVARGYLNRPELTAERFIS--YS 828 Query: 652 ADGS----------------RMYRTGDLVRRRADGEIEYLGRTDHQVKIRGLRIELGEIE 695 GS +Y+TGD R DG IEYLGR D+QVKIRG RIELGEIE Sbjct: 829 DLGSIGYLTPMPHAPCPIPHALYKTGDRARYLRDGTIEYLGRLDNQVKIRGFRIELGEIE 888 Query: 696 AQLLAQPGVAAAVVVALVEPGRPARLVGYAADPGGMLEAEALRAALLQSLPDYMVPQRLI 755 L V AA+VV + RLV Y E LR L ++LPDYM+P + I Sbjct: 889 TVLSQHSEVQAAIVVVTEDTTGDKRLVAYIVSENP--EITDLRQYLAKNLPDYMIPSQFI 946 Query: 756 LLPALPLNANGKVDRKALPRPDFNEQGGYEAPQGQTEIGLAAIWAEVLRLQRVGRHDNFF 815 L ALPL NGKVDR+ALP+P F AP+ TE L IW +L L VG DNFF Sbjct: 947 TLDALPLTPNGKVDRRALPKPQFKTSSHTIAPRTPTEELLLNIWQNILNLNSVGITDNFF 1006 Query: 816 ELGGDSILSLQIVARAHEQ-GWPLTPRQLFQSQTVAELA 853 LGG S+L +++V++ + G ++ RQ+F++ T+AELA Sbjct: 1007 ALGGHSLLVIRLVSQIQQVFGVDISLRQIFENPTIAELA 1045 Score = 275 bits (702), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 141/366 (38%), Positives = 211/366 (57%), Gaps = 20/366 (5%) Query: 889 LQGELEDVYPLSPMQQGMLFHTMESPGSGLYVNQLSVRVEG-LDEARFAQAWQSVLARHP 947 ++ + D+Y LSPMQ GMLFHT+ +P SG+Y Q S + G L+ F QAWQ V+ RH Sbjct: 1 MESSIIDIYELSPMQAGMLFHTLYAPNSGVYFEQRSCLIRGNLNLPAFRQAWQRVVERHS 60 Query: 948 VMRTGFLWQAGYAQPLQAVWRTLAFGIEVQDWS---ARADDAELPQAIAAFAAADLARGF 1004 V+RT F + + +PLQ V+ + + DW A A+L + F D GF Sbjct: 61 VLRTAFHY-SELEKPLQVVYDYVELPWQELDWCGVEATVQKAKLTE----FLECDCNSGF 115 Query: 1005 DLLQPPLVRATLLRLGPGQHQLVWTMHHILLDGWSTSALMQELMLAYGG------QPLPA 1058 +L QPPL+R ++RL ++Q +W+ HH+L+DGW L+ E+ Y LP+ Sbjct: 116 NLQQPPLMRCAVIRLEANKYQFIWSHHHLLMDGWCNGILLTEVFTLYKAFCQSEDVTLPS 175 Query: 1059 PGPDYAQYIGWLATLDPQAAQRYWMGALQALDGPSLLAEGVRPDPARRGFGKLYGHCDAA 1118 P P Y YI WL +P+ A+ +W LQ P++L + + ++ Sbjct: 176 PIP-YGNYILWLQQQNPEQAESFWRKQLQDFTAPTVLGNKIN---NQSSIFSQQSKVNSQ 231 Query: 1119 ATRRLEQFARSQRVTLNTLVQGAWSLALARHKRSTAVAFGATVSGRPAALPGVEKSLGLF 1178 T +L+ F R R+TLN LVQGAW+L L+R+ V FG TVSGRP LP VE +GLF Sbjct: 232 QTEQLQNFVRQHRLTLNILVQGAWALLLSRYSGENNVLFGTTVSGRPPELPQVESIVGLF 291 Query: 1179 INTIPIVVEVDGQRRVGDWLRTLQQTNIDSREHEHTPLYDIQRWSGMA-GRALFDSIIVF 1237 INT+P+ V+V+G+ ++ WL+ LQ ++ ++ ++ L DIQ WS + G +LF+S++VF Sbjct: 292 INTLPVRVDVNGEMQIIPWLQQLQAQQVEREQYSYSSLVDIQSWSSVPRGTSLFESLLVF 351 Query: 1238 ENFPIS 1243 EN+P+S Sbjct: 352 ENYPVS 357 >all2643 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Nos Nostoc sp. PCC 7120 Length = 1102 Score = 672 bits (1734), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/913 (42%), Positives = 542/913 (59%), Gaps = 71/913 (7%) Query: 1 LQGRDQEATRRFWEIQLARLQQPT---RLADAMPRPSTPQSGHGEHRELLDATLTARLNE 57 LQ +D+ A + FW+ QLA PT R A + TPQ E L T L + Sbjct: 187 LQQQDKIAAKTFWQKQLAGFTTPTVIQRFAQRENKNLTPQ----EQTRSLTPNQTTGLQQ 242 Query: 58 AARAQRITLNTLVQAAWALLLQRYTYAAHDQGVVFGATVAGRPAELTGVEQLLGLFINTL 117 A+ Q++TLNTL+Q A+ALLL RY + VVFGAT +GRPA L GVE ++GLFINTL Sbjct: 243 WAKEQQLTLNTLLQGAFALLLSRY---CNTTDVVFGATSSGRPATLAGVESMVGLFINTL 299 Query: 118 PVIVATPPHQPAGDWMRALQAQNLQAREYEHTPLVDIQRWSGQG-AQALFDSILVFENYP 176 PV V P +W++ LQAQ +A EYE+T L++IQ WS +LFDSILVFENYP Sbjct: 300 PVRVQVSPTDDLVEWLQKLQAQQAEALEYEYTSLLEIQEWSELTPGTSLFDSILVFENYP 359 Query: 177 VDAT-LSQGAPAGLAFSSVRHREETNYPMTVVVNAGDTLQLQLRYARAQFAHEMVERIGA 235 VD + +SQ L ++ E T++P+T++V+ G+ L L+++Y R +F + ++ Sbjct: 360 VDTSGISQNQ--DLRIIDIQSLEWTSFPLTMLVSVGNQLSLKVKYDRNRFTDNAITQLLE 417 Query: 236 HLRHLLQVLAEHPQQAIGSLGLLPGDE---LAAWRESGVNRELHAFDAPVHRLIERQAAA 292 H +LL +++ P Q IG+L LL E + W ++ L +H+ + Q Sbjct: 418 HFCNLLLGMSQ-PGQTIGNLPLLTQQEYETIHKWNQTEAYYPLEC----IHQQFDIQVER 472 Query: 293 TPSAAALLYEDLVLDYRSLNQQANRLAHRLLAEGAGPERIVGVAARRAPEMVVALLAVLK 352 TP A+++E+ L YR LNQ+AN+LAH L G PE VG+ R+ EMV+ +L +LK Sbjct: 473 TPDDVAVVFEEQQLTYRELNQRANQLAHYLQTWGVQPETPVGIYIERSLEMVIGILGILK 532 Query: 353 AGAAYLPLDPDLPPARLADMMADSGLSLLLTQTALRAEL----TAPAAVRVLE------L 402 AG Y+PLDP P +RL ++ ++ + ++LTQ +L +L ++ A+ +VL L Sbjct: 533 AGGCYVPLDPAYPASRLTYIINETQVPVVLTQESLLEKLLGFTSSQASSKVLNKTLCLCL 592 Query: 403 DAPGQPWAEGMPDHDPGIEVAPDGLAYVIYTSGSTGKPKGAGNRHVSLHNRLAWMQEAYP 462 D Q + PD++P V + Y+IYTSGSTG PKG N H + NRL WMQ+ Y Sbjct: 593 DTDWQEITQK-PDNNPITNVNHEDAIYIIYTSGSTGTPKGVINTHRGVSNRLYWMQQQYG 651 Query: 463 IGPGNTVLQKTPFGFDVSVWEFFWPLMTGARLALAAPDEHRDPALLAARIRRHAVDTLHF 522 + G VLQKTPF FDVSVWEFFW L+ G RL ++ P H+DP L I +H + TLHF Sbjct: 652 LERGEVVLQKTPFSFDVSVWEFFWTLLNGGRLVMSKPGGHQDPNYLLEIIAQHKITTLHF 711 Query: 523 VPSMLQAFVAHPD-SAQCHSLRQVICSGEALPAELQEQAFARLPQIALHNLYGPTEAAID 581 VP+ML F+ P+ + +CHSL++VICSGEAL E+Q + F L LHNLYGPTEAAID Sbjct: 712 VPTMLGVFLEAPNLNERCHSLKRVICSGEALSIEIQNRFFQHL-DAELHNLYGPTEAAID 770 Query: 582 VTHWTCRPGER--SVPIGRPISHTAAYVLDGGLNPLPHGIAGELYLGGIGLARGYLGRPG 639 VT+W C+P + +VPIGRPI++T Y+L+ L P+P GI GE+Y+GG+G+ARGY RP Sbjct: 771 VTYWQCQPTDNLHTVPIGRPITNTQIYLLNDYLQPVPLGIPGEIYIGGVGVARGYWKRPD 830 Query: 640 LSAERFVADPFAADG-----------------------SRMYRTGDLVRRRADGEIEYLG 676 L+ ERFV D S +Y+TGDL R DG +EYLG Sbjct: 831 LTTERFVGGLGTGDWGLGTGEKNNPTLNSQLSTQHSALSTLYKTGDLARYLPDGNLEYLG 890 Query: 677 RTDHQVKIRGLRIELGEIEAQLLAQPGVAAAVVVALVEPGRPARLVGYAADPGGMLEA-- 734 R D+QVKIRGLRIELGEIEA + P V AVV+ + RL Y LE+ Sbjct: 891 RLDNQVKIRGLRIELGEIEAVINQHPDVQQAVVILDSKQADNQRLGAYVVQKSTSLESPD 950 Query: 735 --EALRAALLQSLPDYMVPQRLILLPALPLNANGKVDRKALPRPDF--NEQGGYEAPQGQ 790 L L LP+YM+P ++L LPL NGK++R+ALP P+ + Y AP+ Sbjct: 951 FTSELEKLLASQLPEYMLPSVFVMLSELPLLPNGKINRQALPTPETVRHANQSYIAPRNS 1010 Query: 791 TEIGLAAIWAEVLRLQRVGRHDNFFELGGDSILSLQIVAR---AHEQGWPLTPRQLFQSQ 847 TE +A I A+VLRL+R+G +NFFELGG+S+ ++++ +R A + PL +F+ Sbjct: 1011 TETIIANILADVLRLERMGVDENFFELGGNSLSAIRVTSRLREAFQLDLPL--HSVFEKP 1068 Query: 848 TVAELAQQCDQLQ 860 T+A LA++ LQ Sbjct: 1069 TIAGLAERIMILQ 1081 Score = 279 bits (714), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 143/357 (40%), Positives = 214/357 (59%), Gaps = 5/357 (1%) Query: 892 ELEDVYPLSPMQQGMLFHTMESPGSGLYVNQLSVRVEG-LDEARFAQAWQSVLARHPVMR 950 +E++YPLSPMQQGMLFHT+ +P +G+YV Q+ + +EG LD AW V+ HP +R Sbjct: 9 NIENIYPLSPMQQGMLFHTLLTPQAGVYVPQVCLYLEGKLDINALKTAWNQVVINHPALR 68 Query: 951 TGFLWQAGYAQPLQAVWRTLAFGIEVQDWSARADDAELPQAIAAFAAADLARGFDLLQPP 1010 T F W+ +P Q V+R + ++ DW DAE + F +D FD+ QPP Sbjct: 69 TAFYWEQR-DKPFQVVFRQVEIPWKILDWQT-ISDAEQQVELEIFLESDRTFSFDIKQPP 126 Query: 1011 LVRATLLRLGPGQHQLVWTMHHILLDGWSTSALMQELMLAYGGQPLPAPGPD-YAQYIGW 1069 L+R TL++L ++ L+WT HH++LDGWS++ +++E+ Y P P Y YI W Sbjct: 127 LLRLTLIQLSATKYILIWTQHHLILDGWSSALVIKEVFQNYYNSPSYYPNSRPYGDYIAW 186 Query: 1070 LATLDPQAAQRYWMGALQALDGPSLLAEGVRPDPARRGFGKLYGHCDAAATRRLEQFARS 1129 L D AA+ +W L P+++ + + + T L+Q+A+ Sbjct: 187 LQQQDKIAAKTFWQKQLAGFTTPTVIQRFAQRENKNLTPQEQTRSLTPNQTTGLQQWAKE 246 Query: 1130 QRVTLNTLVQGAWSLALARHKRSTAVAFGATVSGRPAALPGVEKSLGLFINTIPIVVEVD 1189 Q++TLNTL+QGA++L L+R+ +T V FGAT SGRPA L GVE +GLFINT+P+ V+V Sbjct: 247 QQLTLNTLLQGAFALLLSRYCNTTDVVFGATSSGRPATLAGVESMVGLFINTLPVRVQVS 306 Query: 1190 GQRRVGDWLRTLQQTNIDSREHEHTPLYDIQRWSGMA-GRALFDSIIVFENFPISRS 1245 + +WL+ LQ ++ E+E+T L +IQ WS + G +LFDSI+VFEN+P+ S Sbjct: 307 PTDDLVEWLQKLQAQQAEALEYEYTSLLEIQEWSELTPGTSLFDSILVFENYPVDTS 363 >PA2402_4 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Pae Pseudomonas aeruginosa Length = 1074 Score = 662 bits (1709), Expect = 0.0, Method: Compositional matrix adjust. Identities = 413/880 (46%), Positives = 529/880 (60%), Gaps = 40/880 (4%) Query: 1 LQGRDQEATRRFWEIQLARLQQPTRLADAMPRPS-TPQSGHGEHRELLDATLTARLNEAA 59 LQ +D AT FW Q+A L +PTRL +A+ +P T +G GEH +DAT TARL + A Sbjct: 184 LQRQDAAATEAFWREQMAALDEPTRLVEALAQPGLTSANGVGEHLREVDATATARLRDFA 243 Query: 60 RAQRITLNTLVQAAWALLLQRYTYAAHDQGVVFGATVAGRPAELTGVEQLLGLFINTLPV 119 R ++TLNTLVQA WALLLQRYT VVFGATV+GRPA+L GVE +GLFINTLPV Sbjct: 244 RRHQVTLNTLVQAGWALLLQRYT---GQHTVVFGATVSGRPADLPGVENQVGLFINTLPV 300 Query: 120 IVATPPHQPAGDWMRALQAQNLQAREYEHTPLVDIQRWSGQGAQALFDSILVFENYPVDA 179 +V P + ++ LQ QNL RE EHTPL ++QRW+G G +A+FD++LVFENYPVD Sbjct: 301 VVTLAPQMTLDELLQGLQRQNLALREQEHTPLFELQRWAGFGGEAVFDNLLVFENYPVDE 360 Query: 180 TLSQGAPAGLAFSSVRHREETNYPMTVVVNAGDTLQLQLRYARAQFAHEMVERIGAHLRH 239 L + + G+ F +V E+TNYP+ + + GD+L LQ Y R F +ER+G HL Sbjct: 361 VLERSSAGGVRFGAVAMHEQTNYPLALALGGGDSLSLQFSYDRGLFPAATIERLGRHLTT 420 Query: 240 LLQVLAEHPQQAIGSLGLLPGDELAA----WRESGVNRELHAFDAP--VHRLIERQAAAT 293 LL+ AEHPQ+ + L +L EL+A W NR + A VH+ + +A Sbjct: 421 LLEAFAEHPQRRLVDLQMLEKAELSAIGAIW-----NRSDSGYPATPLVHQRVAERARMA 475 Query: 294 PSAAALLYEDLVLDYRSLNQQANRLAHRLLAEGAGPERIVGVAARRAPEMVVALLAVLKA 353 P A A+++++ L Y L+ +ANRLAH L+A G GPE V +A +R+ E++VA LAVLKA Sbjct: 476 PDAVAVIFDEEKLTYAELDSRANRLAHALIARGVGPEVRVAIAMQRSAEIMVAFLAVLKA 535 Query: 354 GAAYLPLDPDLPPARLADMMADSGLSLLLTQTALRAELTAPAAVRVLELDAPGQPWAEGM 413 G AY+PLD + P RL MM DS LLLT + L L P + L +D + WA G Sbjct: 536 GGAYVPLDIEYPRERLLYMMQDSRAHLLLTHSHLLERLPIPEGLSCLSVDRE-EEWA-GF 593 Query: 414 PDHDPGIEVAPDGLAYVIYTSGSTGKPKGAGNRHVSLHNRLAWMQEAYPIGPGNTVLQKT 473 P HDP + + D LAYVIYTSGSTG PKG H L + E Y + P + L Sbjct: 594 PAHDPEVALHGDNLAYVIYTSGSTGMPKGVAVSHGPLIAHIVATGERYEMTPEDCELHFM 653 Query: 474 PFGFDVSVWEFFWPLMTGARLALAAPDEHRDPALLAARIRRHAVDTLHFVPSMLQAFVAH 533 F FD S + PL+ GAR+ L D P A + RH V F P LQ H Sbjct: 654 SFAFDGSHEGWMHPLINGARV-LIRDDSLWLPERTYAEMHRHGVTVGVFPPVYLQQLAEH 712 Query: 534 PDSAQCHSLRQVIC-SGEALPAELQEQAFARLPQIALHNLYGPTEAAIDVTHWTCRPGER 592 + +V C G+A+ + A+ L L N YGPTE + W R G+ Sbjct: 713 AERDGNPPPVRVYCFGGDAVAQASYDLAWRALKPKYLFNGYGPTETVVTPLLWKARAGDA 772 Query: 593 S----VPIGRPISHTAAYVLDGGLNPLPHGIAGELYLGGIGLARGYLGRPGLSAERFVAD 648 +PIG + + + Y+LDG LN LP G+AGELYLGG G+ARGYL RP L+AERFV D Sbjct: 773 CGAAYMPIGTLLGNRSGYILDGQLNLLPVGVAGELYLGGEGVARGYLERPALTAERFVPD 832 Query: 649 PFAADGSRMYRTGDLVRRRADGEIEYLGRTDHQVKIRGLRIELGEIEAQLLAQPGVAAAV 708 PF A GSR+YR+GDL R RADG ++YLGR DHQVKIRG RIELGEIEA+L P V AV Sbjct: 833 PFGAPGSRLYRSGDLTRGRADGVVDYLGRVDHQVKIRGFRIELGEIEARLREHPSVREAV 892 Query: 709 VVALVEPGRPA-RLVGY--------AADPGGMLEAEA-LRAALLQSLPDYMVPQRLILLP 758 VVA +PG +LVGY A P E A L+ AL + LP+YMVP L+ L Sbjct: 893 VVA--QPGAVGQQLVGYVVAQAPAVADSPEAQAECRAQLKTALRERLPEYMVPSHLLFLA 950 Query: 759 ALPLNANGKVDRKALPRPDFN-EQGGYEAPQGQTEIGLAAIWAEVLRLQRVGRHDNFFEL 817 +PL NGK+DRK LP+PD + Q Y AP+ E +A IWAEVL+LQ+VG DNFFEL Sbjct: 951 RMPLTPNGKLDRKGLPQPDASLLQQVYVAPRSDLEQQVAGIWAEVLQLQQVGLDDNFFEL 1010 Query: 818 GGDSILSLQIVARAH-EQGWPLTPRQLFQSQTV---AELA 853 GG S+L++Q+ AR E G L LFQ++++ AELA Sbjct: 1011 GGHSLLAIQVTARMQSEVGVELPLAALFQTESLQAYAELA 1050 Score = 315 bits (806), Expect = 8e-85, Method: Compositional matrix adjust. Identities = 172/370 (46%), Positives = 233/370 (62%), Gaps = 6/370 (1%) Query: 892 ELEDVYPLSPMQQGMLFHTMESPGSGLYVNQLSVRVEGLDEARFAQAWQSVLARHPVMRT 951 E+ED+YPLSPMQQGMLFH++ S Y+NQ+ V V GLD RF AWQS L RH ++R+ Sbjct: 8 EVEDIYPLSPMQQGMLFHSLYEQASSDYINQMRVDVSGLDLPRFRAAWQSALDRHAILRS 67 Query: 952 GFLWQAGYAQPLQAVWRTLAFGIEVQDWSARADDAELPQAIAAFAAADLARGFDLLQPPL 1011 GF WQ QPLQ V+R +D S A+ A+ A AAA+ RGF+L + PL Sbjct: 68 GFAWQGELQQPLQIVYRQRQLPFAEEDLSQAANRD---AALLALAAAERERGFELQRAPL 124 Query: 1012 VRATLLRLGPGQHQLVWTMHHILLDGWSTSALMQELMLAYGGQ-PLPAPGPDYAQYIGWL 1070 +R L++ G+H L++T HHILLDGWS + L+ E++ +Y G+ P Y+ YI WL Sbjct: 125 LRLLLVKTAEGEHHLIYTHHHILLDGWSNAQLLSEVLESYAGRSPEQLRDGRYSDYIAWL 184 Query: 1071 ATLDPQAAQRYWMGALQALDGPSLLAEGV-RPD-PARRGFGKLYGHCDAAATRRLEQFAR 1128 D A + +W + ALD P+ L E + +P + G G+ DA AT RL FAR Sbjct: 185 QRQDAAATEAFWREQMAALDEPTRLVEALAQPGLTSANGVGEHLREVDATATARLRDFAR 244 Query: 1129 SQRVTLNTLVQGAWSLALARHKRSTAVAFGATVSGRPAALPGVEKSLGLFINTIPIVVEV 1188 +VTLNTLVQ W+L L R+ V FGATVSGRPA LPGVE +GLFINT+P+VV + Sbjct: 245 RHQVTLNTLVQAGWALLLQRYTGQHTVVFGATVSGRPADLPGVENQVGLFINTLPVVVTL 304 Query: 1189 DGQRRVGDWLRTLQQTNIDSREHEHTPLYDIQRWSGMAGRALFDSIIVFENFPISRSLEA 1248 Q + + L+ LQ+ N+ RE EHTPL+++QRW+G G A+FD+++VFEN+P+ LE Sbjct: 305 APQMTLDELLQGLQRQNLALREQEHTPLFELQRWAGFGGEAVFDNLLVFENYPVDEVLER 364 Query: 1249 RAQAGLXAGA 1258 + G+ GA Sbjct: 365 SSAGGVRFGA 374