BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0144.p (432 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 609 e-174 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 577 e-164 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 572 e-163 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 549 e-156 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 296 9e-80 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 609 bits (1570), Expect = e-174, Method: Compositional matrix adjust. Identities = 290/427 (67%), Positives = 352/427 (82%), Gaps = 2/427 (0%) Query: 5 TTNAKHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISKTFFPSDNEFVSLILTFGTFGAG 64 T N SK ++ RV SGNFLEM+DF +YG+YA I+ TFFP+DNEF+SL+L+ TFG G Sbjct: 3 THNPNESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVG 62 Query: 65 FLMRPLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGVAAPILVLTGRL 124 FLMRPLGA+ILG+YIDR GRR GLI+TL +MA GTLLIA VPGYATIG+AAP+LVL GRL Sbjct: 63 FLMRPLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRL 122 Query: 125 LQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQSLSPVQI 184 LQGFSAGVELGGVSVYLAE++TPG KGF+VSWQSASQQ A+M +AL+G L+S LSP ++ Sbjct: 123 LQGFSAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEM 182 Query: 185 SDWGWRIPFFIGCMIVPAIFIIRRSLQETDEFLARKRHPSFGEIMSSIAQNWKIVVAGMM 244 +WGWR+PF +GC+IVP +F+IRRSLQET+EF RK P+ GEI S+ +NW++V AG + Sbjct: 183 GEWGWRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGAGTL 242 Query: 245 MVVMTTVSFYLITVYTPTFGKNVLKLSASDSLIVTFCVGLSNFCWLPIMGALSDRVGRRP 304 +VVMTTVSFYLIT YTPTFGK+VL LS DSLIVT CVG SNF WLP+MG++SDR+GRRP Sbjct: 243 LVVMTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRP 302 Query: 305 VLVAFTLLTLLTAYPVMSWLVSDISFKNLLITELWLSFLYASYNGAAVVALTEVMPGHVR 364 +L+ FT LTLLTAYP M WL+++ SF LL ELWLSFLY SYNGA VV LTE+MP VR Sbjct: 303 LLITFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVR 362 Query: 365 TVGFSLAYSLATAIFGGFTPLVSTWLIETSGDKAAPGYWMSFAAVCGLLATLVLYR--GK 422 T GFSLAYSLATAIFGGFTP ++TWLI +G+KA PG W+SFAA+CGL+ATL++ + G+ Sbjct: 363 TTGFSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVKPAGR 422 Query: 423 SAAATVS 429 TV+ Sbjct: 423 HVHTTVT 429 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 577 bits (1488), Expect = e-164, Method: Compositional matrix adjust. Identities = 274/424 (64%), Positives = 338/424 (79%) Query: 5 TTNAKHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISKTFFPSDNEFVSLILTFGTFGAG 64 T N SK + RV SGNFLEMFDF +YG+YA+ I+ TFFP+ N F+SL+L+ TFGAG Sbjct: 3 THNPNESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAG 62 Query: 65 FLMRPLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGVAAPILVLTGRL 124 FLMRPLGAI+LG+YIDR GRR GLI+TL +MA GT+LIA VPGY TIG+AAP+LVL GRL Sbjct: 63 FLMRPLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRL 122 Query: 125 LQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQSLSPVQI 184 LQGFSAG E GGVSVYL+E+ATPG KGFYVSWQS SQQ A+M +AL+G L+S LSP ++ Sbjct: 123 LQGFSAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEM 182 Query: 185 SDWGWRIPFFIGCMIVPAIFIIRRSLQETDEFLARKRHPSFGEIMSSIAQNWKIVVAGMM 244 +WGWR+PF IGC+IVP +F IRRSL+ET+EF RK P+ GE++ S+ +NW++ AG + Sbjct: 183 GEWGWRVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWRLAGAGTL 242 Query: 245 MVVMTTVSFYLITVYTPTFGKNVLKLSASDSLIVTFCVGLSNFCWLPIMGALSDRVGRRP 304 + VMTTVSFYLIT YTPTFG+NVL +S DSLIVT CVG SN WLP+MG+LSDR+GRR Sbjct: 243 LAVMTTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRT 302 Query: 305 VLVAFTLLTLLTAYPVMSWLVSDISFKNLLITELWLSFLYASYNGAAVVALTEVMPGHVR 364 L+ F+ LTLLTAYP M+WL+++ SF LL ELWLSFLY YNGA +V LTE+MP +R Sbjct: 303 PLIVFSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLR 362 Query: 365 TVGFSLAYSLATAIFGGFTPLVSTWLIETSGDKAAPGYWMSFAAVCGLLATLVLYRGKSA 424 T GFSLAYSLATAIFGGFTP ++T LI +G+KA PG W+SFAA+CGL+ATL + + + Sbjct: 363 TTGFSLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKPQPR 422 Query: 425 AATV 428 A + Sbjct: 423 PAAM 426 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 572 bits (1475), Expect = e-163, Method: Compositional matrix adjust. Identities = 277/426 (65%), Positives = 341/426 (80%), Gaps = 4/426 (0%) Query: 4 TTTNAKHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISKTFFPSDNEFVSLILTFGTFGA 63 T ++ +LRVTSGNFLE FDFFL+GFYA+YI++TFFP+++EF SL+LTF FG+ Sbjct: 5 TPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGS 64 Query: 64 GFLMRPLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGVAAPILVLTGR 123 GFLMRP+GAI+LG+YIDR+GRR+GL+VTLAIM GTLLIA VPGY TIG+AAP LVL GR Sbjct: 65 GFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGR 124 Query: 124 LLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQSLSPVQ 183 LLQGFSAGVELGGVSVYL+E+ATPGNKGFY SWQSASQQ AI+ +ALIGY ++ +L Sbjct: 125 LLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDA 184 Query: 184 ISDWGWRIPFFIGCMIVPAIFIIRRSLQETDEFLARKRHPSFGEIMSSIAQNWKIVVAGM 243 IS+WGWRIPFFIGCMI+P IF++RRSLQET+ FL RK P EI ++IA+NW+I+ AG Sbjct: 185 ISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAGT 244 Query: 244 MMVVMTTVSFYLITVYTPTFGKNVLKLSASDSLIVTFCVGLSNFCWLPIMGALSDRVGRR 303 ++V MTT +FY ITVYTPT+G+ VL LSA DSLIVT VG+SNF WLPI GA+SDR+GRR Sbjct: 245 LLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRR 304 Query: 304 PVLVAFTLLTLLTAYPVMSWLVSDISFKNLLITELWLSFLYASYNGAAVVALTEVMPGHV 363 VL+ TLL L+T +PVM WL + F + + LW SF + YNGA V ALTEVMP +V Sbjct: 305 AVLMGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYV 364 Query: 364 RTVGFSLAYSLATAIFGGFTPLVSTWLIETSGDKAAPGYWMSFAAVCGLLATLVLY---- 419 RTVGFSLA+SLATAIFGG TP +ST L++ +GDK++PG+W+ AA+CGL AT +L+ Sbjct: 365 RTVGFSLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLFVRLS 424 Query: 420 RGKSAA 425 RG AA Sbjct: 425 RGYIAA 430 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 549 bits (1414), Expect = e-156, Method: Compositional matrix adjust. Identities = 277/396 (69%), Positives = 328/396 (82%) Query: 8 AKHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISKTFFPSDNEFVSLILTFGTFGAGFLM 67 + SK + RV SGNFLEM+DF +YGFYA+ I+KTFFP DN F SL+L+ TFGAGFLM Sbjct: 3 SNKSKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLM 62 Query: 68 RPLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGVAAPILVLTGRLLQG 127 RPLGA+ LG+YIDR GRRQGLI+TL +MA+GTLLIAFVPGYAT+GVAAP+LVL GRLLQG Sbjct: 63 RPLGAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQG 122 Query: 128 FSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQSLSPVQISDW 187 FSAGVELGGVSVYL+E+ATPG KGF+VSWQSASQQ A++ + L+G L++Q LSP + +W Sbjct: 123 FSAGVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEW 182 Query: 188 GWRIPFFIGCMIVPAIFIIRRSLQETDEFLARKRHPSFGEIMSSIAQNWKIVVAGMMMVV 247 GWR+PFFIGC+IVPA+F+IRRSL+ET EF AR PS +++ SI QN+ +V+AG MVV Sbjct: 183 GWRVPFFIGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVV 242 Query: 248 MTTVSFYLITVYTPTFGKNVLKLSASDSLIVTFCVGLSNFCWLPIMGALSDRVGRRPVLV 307 MTTVSFYLIT YTPTFGKN L+LS DSL+VT C+GLSNF WLP+MGA SDR+GR+P+L+ Sbjct: 243 MTTVSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLL 302 Query: 308 AFTLLTLLTAYPVMSWLVSDISFKNLLITELWLSFLYASYNGAAVVALTEVMPGHVRTVG 367 + L LLTAYP +SWLV + SF LL ELWLSFLY+SYNGA VVALTEVMP VRT G Sbjct: 303 GASALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTG 362 Query: 368 FSLAYSLATAIFGGFTPLVSTWLIETSGDKAAPGYW 403 FSLAYSLATA FGGFTP V TWLI T ++AAPG W Sbjct: 363 FSLAYSLATATFGGFTPAVCTWLIHTLDNRAAPGIW 398 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 296 bits (757), Expect = 9e-80, Method: Compositional matrix adjust. Identities = 165/416 (39%), Positives = 236/416 (56%), Gaps = 1/416 (0%) Query: 11 SKLSTVLRVTSGNFLEMFDFFLYGFYASYISKTFFPSDNEFVSLILTFGTFGAGFLMRPL 70 S+ V GN LE +DF +YGF +S I++ FFPS +E+ SL++ TFG GF MRP+ Sbjct: 9 SRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFMRPV 68 Query: 71 GAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGVAAPILVLTGRLLQGFSA 130 G ++LG Y DR GR+ + + + +M + +IAF P YA IGV AP+L++ R+LQGF+ Sbjct: 69 GGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFAT 128 Query: 131 GVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQSLSPVQISDWGWR 190 G E + +L E A P +G Y SWQ Q A+ A A +G LV+ L + WGWR Sbjct: 129 GGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWR 188 Query: 191 IPFFIGCMIVPAIFIIRRSLQETDEFLARKRHPSFGEIMSSIAQNWKI-VVAGMMMVVMT 249 +PF G +I P IRR + ET+ FL R P + + + + ++ V+ M + V+ Sbjct: 189 VPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLTVVG 248 Query: 250 TVSFYLITVYTPTFGKNVLKLSASDSLIVTFCVGLSNFCWLPIMGALSDRVGRRPVLVAF 309 TVSFY++ V PTF L L + +V +P+ G LSDRVGRRPVL+ Sbjct: 249 TVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLLVA 308 Query: 310 TLLTLLTAYPVMSWLVSDISFKNLLITELWLSFLYASYNGAAVVALTEVMPGHVRTVGFS 369 TL +L YP+ +W+ + S LL+ +L L + G A A+ E P VR+ G + Sbjct: 309 TLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGLA 368 Query: 370 LAYSLATAIFGGFTPLVSTWLIETSGDKAAPGYWMSFAAVCGLLATLVLYRGKSAA 425 +AY+LA +FGGF P + TWL E G AP +++ AA GLLATL L G + A Sbjct: 369 VAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLREGATPA 424