BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0067.p (183 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value L189881 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 205 4e-53 PA3968 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 198 5e-51 HI0694 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 196 3e-50 PM1605 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 190 2e-48 NMB1496 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 189 3e-48 >L189881 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Lla Lactococcus lactis Length = 185 Score = 205 bits (522), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 99/174 (56%), Positives = 128/174 (73%), Gaps = 2/174 (1%) Query: 1 LNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAHPRR 60 NKP+ V+++F+ R+TL DYI IPNVY AGRLD DSEGLLLLTDDGKL H + P+ Sbjct: 12 FNKPYDVLTKFTDGEGRKTLKDYIKIPNVYAAGRLDKDSEGLLLLTDDGKLNHLLTDPKS 71 Query: 61 KLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQRQNQ 120 K KTYL QVEG+ SPEA KL++ L L D T ++ +LI+EP W+W R PPIR+R+ Sbjct: 72 KSYKTYLVQVEGEFSPEAAQKLQKGLLLKDGKTLPAKVKLIDEPDWLWERTPPIRERKAI 131 Query: 121 PTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREV 174 PTSW+ ++I EGKNRQ+RRMTAAVG PTLRL+R +IG +SL + GE++ + Sbjct: 132 PTSWVEISIKEGKNRQIRRMTAAVGFPTLRLIRWSIGQYSLGN--LKSGEYKII 183 >PA3968 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Pae Pseudomonas aeruginosa Length = 189 Score = 198 bits (504), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 105/174 (60%), Positives = 128/174 (73%), Gaps = 3/174 (1%) Query: 1 LNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAHPRR 60 NKPF V++QF+ R TL D+I +P VYPAGRLD DSEGLLLLT+DG+LQ IA PR Sbjct: 14 FNKPFDVLTQFNDEQGRSTLKDFIPVPGVYPAGRLDRDSEGLLLLTNDGRLQARIADPRH 73 Query: 61 KLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQRQNQ 120 KLPKTY QVEG P E L +LR+ + L D T ++ARL++EP +W R PP+R R++ Sbjct: 74 KLPKTYWVQVEGTPDEEQLRRLREGVTLNDGPTLPAEARLLDEPT-LWERVPPVRFRKSV 132 Query: 121 PTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREV 174 PT W+ L I EG+NRQVRRMTAAVGLPTLRLVR+ IGP+SL + GEWREV Sbjct: 133 PTHWLELVIREGRNRQVRRMTAAVGLPTLRLVRVRIGPWSLDGLGL--GEWREV 184 >HI0694 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Hin Haemophilus influenzae Length = 240 Score = 196 bits (498), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 93/161 (57%), Positives = 121/161 (75%), Gaps = 1/161 (0%) Query: 1 LNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAHPRR 60 NKPF V++QF+ R TL D+I IPNVY AGRLD DSEGLL+LT++G+LQH +A P+ Sbjct: 56 FNKPFDVLTQFTDEQGRATLKDFISIPNVYAAGRLDRDSEGLLILTNNGELQHRLADPKF 115 Query: 61 KLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQRQNQ 120 K KTY QVEG P L +LR+ ++L D VT+ ++ RLI EP +W RNPPIR+R+N Sbjct: 116 KTEKTYWVQVEGIPEETDLAQLRKGVELKDGVTKSAKVRLISEPN-LWERNPPIRERKNI 174 Query: 121 PTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSL 161 PTSW+ + ISEG+NRQVRRMTA +G PTLRLVR+++G S+ Sbjct: 175 PTSWLEIKISEGRNRQVRRMTAHIGFPTLRLVRVSMGLLSI 215 >PM1605 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Pmu Pasteurella multocida Length = 241 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 93/179 (51%), Positives = 126/179 (70%), Gaps = 2/179 (1%) Query: 1 LNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAHPRR 60 NKP+ V++QFS R TL +I IP+VYPAGRLD DSEGL+LLT++G++QH +A P+ Sbjct: 54 FNKPYDVLTQFSDEEGRATLKAFIPIPHVYPAGRLDRDSEGLVLLTNNGEIQHRLAVPKF 113 Query: 61 KLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQRQNQ 120 KTY AQVEG P L +LRQ + L D T ++ RL+ EP W+W RNPPIR+R+ Sbjct: 114 NTEKTYFAQVEGIPQETDLAQLRQGVVLNDGKTLPAKVRLVPEPNWLWQRNPPIRERKQI 173 Query: 121 PTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREVDPLEL 179 PTSW+ + I EG+NRQVRRMTA +G PTLRL+R + F+LA + G++R++ +EL Sbjct: 174 PTSWLEIKIHEGRNRQVRRMTAHIGFPTLRLIRYQMALFNLAN--LEQGQYRQLSEVEL 230 >NMB1496 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Nme Neisseria meningitidis MC58 Length = 186 Score = 189 bits (479), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 94/173 (54%), Positives = 119/173 (68%), Gaps = 2/173 (1%) Query: 1 LNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAHPRR 60 NKP+ V+ QFS H + ++L D+I++P YPAGRLD DSEGLLLLTDDG+LQ I P+ Sbjct: 7 FNKPYGVICQFSPHEKHKSLKDFINLPGFYPAGRLDTDSEGLLLLTDDGRLQAQITDPKF 66 Query: 61 KLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIE--EPGWMWPRNPPIRQRQ 118 K PKTY AQ+EG P L+ LR+ +DLG FVT+ + R+++ E +W R PPIR R+ Sbjct: 67 KHPKTYWAQLEGVPDESRLESLRKGIDLGGFVTRPASIRILKHGEADSLWERIPPIRVRK 126 Query: 119 NQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEW 171 P WI +TISEGKNRQVRRMTA G P LRL+R+A G L + PGEW Sbjct: 127 TVPDFWIEITISEGKNRQVRRMTAKAGYPCLRLIRVASGRLKLFDLDLKPGEW 179