BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0037.p (687 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value XF0384 [P] COG1629 Outer membrane receptor proteins, mostly Fe t... 350 9e-96 PA0781 [P] COG1629 Outer membrane receptor proteins, mostly Fe t... 323 8e-88 CC0214 Non COG 299 2e-80 NMB0964 [P] COG1629 Outer membrane receptor proteins, mostly Fe ... 250 9e-66 NMA1161 [P] COG1629 Outer membrane receptor proteins, mostly Fe ... 240 6e-63 >XF0384 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport Xfa Xylella fastidiosa 9a5c Length = 681 Score = 350 bits (897), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 236/655 (36%), Positives = 334/655 (50%), Gaps = 46/655 (7%) Query: 52 LQPIVVTATPF-GSQEDVQVLTPAKVIAGDELRNKLGNSLGETLSSELGVSASAFGAGAS 110 L +VVTA P S D+ P ++AG+ L +SLGET++ GV +S FG G Sbjct: 54 LDAVVVTAIPLRDSYSDLS--RPVALLAGERLDEVRASSLGETVAVLPGVQSSNFGPGVG 111 Query: 111 RPIIRGMEGPRVMILQNGMGVSDVSTVSNDHAVATEAATARQIEILRGPAALLYGSGAIG 170 RPIIRG++GPR+ +L NG+ DVSTVS DH+ A E A QIE+L+GP+ LLYGSGAIG Sbjct: 112 RPIIRGLDGPRIAVLNNGLSSQDVSTVSQDHSPAVEPFLANQIEVLKGPSTLLYGSGAIG 171 Query: 171 GLVNVVNDRIPTELVGKPTGTVEGRYGTVDGEKNTS-FSLDTSAGQ-IGLHLDGNYRDTS 228 G+VN+V+ RI VG G E R D NT+ F +D G + +H DG YR+ Sbjct: 172 GVVNIVDGRIAEAPVGGFNGRAEMRLDGGDKHGNTNMFRIDAGNGSALSVHADGVYRNEK 231 Query: 229 DYKIPGNARQGDGSTASGRLPNSFTHESSVGLGASYVSNWGYVGVSAATLDDHYGIP--- 285 DY P GR NSF S +GAS+ ++G+ G+S A D YG P Sbjct: 232 DYDTP-----------KGRQVNSFIDTKSGSMGASFSGDFGFFGLSVARFHDSYGNPGEP 280 Query: 286 -----TSELSFIDLHQNRYDIDTVVNQPFAGIEKLRVRLGYTDYTHIEKQRDGTPDTVFS 340 S++ LHQ+RYD+ + P+ LR LG+T Y HIE + + T F Sbjct: 281 GDPVAGDRGSWLRLHQDRYDLKAGLTDPWGEASALRFSLGHTQYDHIEFEGNEV-GTTFG 339 Query: 341 NRAVQTRWELTHAPLAGWHGTFGVQTEQSNYSALSAATGAAELTPPTRSTSFAGFLVEER 400 RA + R E + A GW FGVQ S + AL G P T + S F + Sbjct: 340 KRASEGRVEASFAFGGGWRTAFGVQGGDSTFQAL----GEESFVPKTNNKSIGVFGLAHN 395 Query: 401 QFGQVLASAGLRGESVSRRPDAGRQGRDFNLLSWSTGALWTFQPGYGLGLTYSLAQRAPT 460 FG A G RG+ V D G R+++ S + + L L A+RAP Sbjct: 396 TFGLFQAEFGARGDQVKYDTDNGVT-RNYHPGSLAFSGDLALSKQWRLTLNVDHAERAPV 454 Query: 461 VEELYSNGPHESTSTFDIGSSQLKKETSHNIELSLQKTEGLVRWKGNLFRNKVNNYIYGR 520 EEL++ GPH +T +++G + LKKE ++ EL L K + + ++ N+IY Sbjct: 455 EEELFAKGPHIATLAYEVGRADLKKEKANQAELGLVFRNDWSDAKVSTYYSRYGNFIY-- 512 Query: 521 TNGQVDDSGAA----DPNGEFTQRFWSQADATIRGAEAEVSYNWNGEGMSG----RLFAD 572 + D+G+ D + R WSQA+A G E E +++ + SG R+F D Sbjct: 513 ----LVDTGSTWFWDDGQRDLPVRQWSQANAIFHGIEGEATFHL-AKNTSGSWDLRVFGD 567 Query: 573 TSRGTLDNLGNIPLQPATRYGVELGYKTGPWASGMKVLRAQRQDRLASFETYATPSYTQV 632 T G L N GN+P RYG EL ++ W + + R ++Q+++A ET T YT V Sbjct: 568 TVSGRLKNGGNLPRIVPARYGAELRWEDAGWRTSLSAKRYEKQNKVAVNET-PTAGYTMV 626 Query: 633 DANLSYTQKLNGVKLTWFALARNLLNQDIRLSTSVLRETVPMGGRNFIVGARTSF 687 DA+L+Y ++ + F NL N+D R+ TS L++ V + GRN+ G R F Sbjct: 627 DAHLAYHIDVDSIAWEVFFDGNNLTNRDARVHTSFLKDDVMLAGRNYTAGLRMFF 681 >PA0781 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport Pae Pseudomonas aeruginosa Length = 687 Score = 323 bits (828), Expect = 8e-88, Method: Compositional matrix adjust. Identities = 227/659 (34%), Positives = 331/659 (50%), Gaps = 41/659 (6%) Query: 56 VVTATPFGSQEDVQVLTPAKVIAGDELRNKLGNSLGETLSSELGVSASAFGAGASRPIIR 115 V+TA P G++ TP+ V+ GDEL + SLGETL+ GVS++ FG GASRP+IR Sbjct: 43 VITANPLGNESPA---TPSSVLEGDELTLRQKGSLGETLNGLPGVSSTYFGPGASRPVIR 99 Query: 116 GMEGPRVMILQNGMGVSDVSTVSNDHAVATEAATARQIEILRGPAALLYGSGAIGGLVNV 175 GM+G R+ +L+NG+G D S++S DHAV + + ++E++RGPAALLYG AIGG+VN Sbjct: 100 GMDGDRIRLLRNGVGALDASSLSYDHAVPEDPNSVERLEVVRGPAALLYGGNAIGGVVNS 159 Query: 176 VNDRIPTELVGKPTGTVEGRYGTVDGEKNTSFSLDTSAGQIGLHLDGNYRDTSDYKIPGN 235 ++RIP+E V G+ E RYG D ++ S +L+ G LH+D R+ +D +IPG Sbjct: 160 FDNRIPSEPVDGIHGSGELRYGGADTTRSRSGALEAGDGNFALHVDAASREFNDVRIPGY 219 Query: 236 A-----RQGDGSTASGRLPNSFTHESSVGLGASYVSNWGYVGVSAATLDDHYGIPTSELS 290 A RQ DG T R+ NS + +G SY GY G+S + D +YG P + Sbjct: 220 AHSSRQRQIDGDTGKHRVQNSDGRQDGGAVGGSYHWEHGYAGLSYSGYDSNYGSPAEDDV 279 Query: 291 FIDLHQNRYDIDTVVNQPFAGIEKLRVRLGYTDYTHIEKQRDGTPDTVFSNRAVQTRWEL 350 + + Q+RY + + L++ YT Y H E + DG T F N + R E Sbjct: 280 RLKMQQDRYAFASEIRDLEGPFTSLKLDAAYTKYEHKEIE-DGETGTTFKNEGYEGRIEA 338 Query: 351 THAPLAGWHGTFGVQTEQSNYSALSAATGAAELTPPTRSTSFAGFLVEERQFGQVL-ASA 409 H PL +G G Q S +SAL G P T + S A F +EE + L S Sbjct: 339 RHRPLGPLNGVVGAQFANSRFSAL----GEEAFVPHTETDSAALFALEEWKLSDRLDLSF 394 Query: 410 GLRGESVSRRPDAGRQGR--------DFNLLSWSTGALWTFQPGYGLGLTYSLAQRAPTV 461 G R E PDA R F S STGA++ P + L T S +RAPT Sbjct: 395 GARLEHTRVDPDAKGNERFAENDGSQSFTTGSLSTGAVYKLTPIWSLAATLSYTERAPTF 454 Query: 462 EELYSNGPHESTSTFDIGSSQLKKETSHNIELSLQKTEGLVRWKGNLFRNKVNNYI---- 517 ELY+NGPH +T T+++G + KE + + +L+L+ G+ + +F ++ +NYI Sbjct: 455 YELYANGPHAATGTYEVGDADADKEKAVSTDLALRFDNGVHKGSVGVFYSRFSNYIGLLA 514 Query: 518 YGRTNGQVDDSGAADPNGEFTQRFWSQADATIRGAEA-------EVSY-NWNGEGMSGRL 569 GR + + AA + + +S A G EA E Y N++ E L Sbjct: 515 SGRHRNEEGEVVAAGDDEALPEYLYSGVRADFYGVEAQDRIHLLESPYGNFDLE-----L 569 Query: 570 FADTSRGTLDNLGN-IPLQPATRYGVELGYKTGPWASGMKVLRAQRQDRLASFETYATPS 628 D +R + G +P R L ++ W + + V A Q R+ E +T Sbjct: 570 SGDYTRAKNKDTGEPLPRIAPLRLNTALIWELQQWQARVDVEHAASQHRVPE-EELSTDG 628 Query: 629 YTQVDANLSYTQKLNGVKLTWFALARNLLNQDIRLSTSVLRETVPMGGRNFIVGARTSF 687 YT + A+L Y L + F NL NQ +R ++S+LR+ VP GR G + +F Sbjct: 629 YTTLGASLGYNFDLGESRWLAFVKGTNLTNQTVRYASSILRDRVPAAGRGIEAGVKVAF 687 >CC0214 Non COG Length = 687 Score = 299 bits (765), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 225/666 (33%), Positives = 324/666 (48%), Gaps = 52/666 (7%) Query: 52 LQPIVVTATPFGSQEDVQVLTPAKVIAGDELRNKLGNSLGETLSSELGVSASAFGAGASR 111 + ++VTA P+G D + A V+ +L LG+ L+ GV ++ FGAGASR Sbjct: 44 VSKVIVTAAPYGVSADALTASVA-VLDRTDLDLAAPKGLGDALAGLPGVRSTTFGAGASR 102 Query: 112 PIIRGMEGPRVMILQNGMGVSDVSTVSNDHAVATEAATARQIEILRGPAALLYGSGAIGG 171 P++RG+ GPRV +L NG+G D S +S DH VAT+ A +IE+LRGPAAL YG AIGG Sbjct: 103 PVVRGLAGPRVQVLTNGVGQIDASALSPDHQVATDPGEAERIEVLRGPAALAYGGSAIGG 162 Query: 172 LVNVVNDRIPTELVGKPTGTVEGRY----GTVDGEKNTSFSLDTSAGQIGLHLDGNYRDT 227 +VN+++DRI T+ +P + GR GT D S ++ + G + L LD R++ Sbjct: 163 VVNIIDDRISTQ---QPIDGMSGRLLASRGTGDDSYALSGAVHATVGPMVLTLDALKRES 219 Query: 228 SDYKI---PGNARQ--GDGSTA---SGRLPNSFTHESSVGLGASYVSNWGYVGVSAATLD 279 DYKI P +ARQ +G TA +GRL NS + G G SYV + G+VG+S D Sbjct: 220 KDYKIPVYPESARQLALEGETAEGGAGRLENSAVDLETFGAGLSYVGDKGFVGMSIKRTD 279 Query: 280 DHYGIPTSELSF---------------IDLHQNRYDIDTVVNQPFAGIEKLRVRLGYTDY 324 YG+P I L Q R D+ + K+R G+ DY Sbjct: 280 STYGVPGHAHEHEGEAEAGHEEESAVTIGLKQTRIDLRGEYDADLGPFAKVRFSGGHADY 339 Query: 325 THIEKQRDGTPDTVFSNRAVQTRWELTHAPLAGWHGTFGVQTEQSNYSALSAATGAAELT 384 TH E + D T F++ + R EL GW G GVQ + N+ A+ G Sbjct: 340 THTEFEGDAV-GTKFTSDGYEGRLELVQTERGGWKGAVGVQALRRNFDAI----GDEAYV 394 Query: 385 PPTRSTSFAGFLVEERQFGQVLASAGLRGESVSRRPDAGRQGRDFNLLSWSTGALWTFQP 444 P T+ T F F + + GLR + +R D+ + DF LS S GA W Sbjct: 395 PKTKITEFGAFTQQRLELDGYGYEGGLRID--TRELDSLKGKADFTNLSGSVGAFWRPTT 452 Query: 445 GYGLGLTYSLAQRAPTVEELYSNGPHESTSTFDIGSSQLKKETSHNIELSLQKTEGLVRW 504 +GL S + RAPT EL++ GPH +T F+IG + LK+ET+ ++E +L + Sbjct: 453 ESFVGLALSRSSRAPTESELFAEGPHAATRGFEIGDADLKEETATSLEATLH-------Y 505 Query: 505 KGNLFRNKVNNYIYGRTNGQVDDSGAADPNGEFTQRFWSQADATIRGAEAEVSYN-WNGE 563 G ++ YI R +G +D D + Q DA RG EAE++Y W Sbjct: 506 GGERVSGDLHLYI-ARYDGFIDLRPTGDEEDGLAVYRYVQTDAEFRGFEAELAYRVWTDG 564 Query: 564 GMSGRLF--ADTSRGTLDNLGNIPLQPATRYGVELGYKTGPWASGMKVLRAQRQDRLASF 621 S L AD RG+ D LG P ++ Y+ W+ ++V R Q+R+A Sbjct: 565 QRSVNLHAGADFVRGSSD-LGPPARIPPYSVSLKASYQAPMWSGDVEVRRTGGQERVAQM 623 Query: 622 ETYATPSYTQVDANLSYTQKLNGVKLTWFALARNLLNQDIRLSTSVLRETVPMGGRNFIV 681 E T YT ++A L++ N ++ F RNL N+++R S L++ P GR Sbjct: 624 E-LPTDGYTVLNATLAWKPAGN-ARVRLFLDGRNLTNEEVREHVSFLKDIAPSPGRQVRA 681 Query: 682 GARTSF 687 G F Sbjct: 682 GIALRF 687 >NMB0964 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport Nme Neisseria meningitidis MC58 Length = 758 Score = 250 bits (638), Expect = 9e-66, Method: Compositional matrix adjust. Identities = 215/720 (29%), Positives = 320/720 (44%), Gaps = 127/720 (17%) Query: 75 KVIAGDELRNKLGNSLGETLSSELGVSASAFGAGASRPIIRGMEGPRVMILQNGMGVSDV 134 K+I+GD LR K N LG+ L G+ AS +G GAS P+IRG G R+ +L + D+ Sbjct: 59 KIISGDTLRQKAVN-LGDALDGVPGIHASQYGGGASAPVIRGQTGRRIKVLNHHGETGDM 117 Query: 135 STVSNDHAVATEAATARQIEILRGPAALLYGSGAIGGLVNVVNDRIPTELVGKPTGTVEG 194 + S DHA+ + A ++Q+EILRGP LLY SG + GLV+V + +IP ++ P V G Sbjct: 118 ADFSPDHAIMVDTALSQQVEILRGPVTLLYSSGNVAGLVDVADGKIPEKM---PENGVSG 174 Query: 195 RYG----TVDGEKNTSFSLDTSAGQ-IGLHLDGNYRDTSDYKI----------------- 232 G + + EK TS ++ G+ LH +G YR + DY + Sbjct: 175 ELGLRLSSGNLEKLTSGGINIGLGKNFVLHTEGLYRKSGDYAVPRYRNLKRLPDSHADSQ 234 Query: 233 ----------------------------PGNARQGDGSTASGRLPNSFTHESSVGLGASY 264 P ++ + D A S ++ + L Sbjct: 235 TGSIGLSWVGEKGFIGVAYSDRRDQYGLPAHSHEYDDCHADIIWQKSLINKRYLQLYPHL 294 Query: 265 VS----NWGYVGVSAATLDD-------HYGIPTSELSFIDLHQNRYDIDTVVNQPFAGIE 313 ++ ++ G+S DD H G P +IDL RY++ QPF G E Sbjct: 295 LTEEDIDYDNPGLSCGFHDDDNAHAHTHSGRP-----WIDLRNKRYELRAEWKQPFPGFE 349 Query: 314 KLRVRLGYTDYTHIEKQRDGTPDTVFSNRAVQTRWELTHAPLAGWHGTFGVQTEQSNYSA 373 LRV L DY H EK D + F+N+ R EL H P+ G++GVQ Q SA Sbjct: 350 ALRVHLNRNDYRHDEKAGDAV-ENFFNNQTQNARIELRHQPIGRLKGSWGVQYLQQKSSA 408 Query: 374 LSAATGAAE--LTPPTRSTSFAGFLVEERQFGQVLASAGLRGES-----------VSRR- 419 LSA + A + + + ++ F VE+ + G+R E + R Sbjct: 409 LSAISEAVKQPMLLDNKVQHYSFFGVEQANWDNFTLEGGVRVEKQKASIQYDKALIDREN 468 Query: 420 ------PDAGRQGRDFNLLSWSTGALWTFQPGYGLGLTYSLAQRAPTVEELYSNGPHEST 473 PD G + S++ W F P + L LT S +R P+ +ELY++G H +T Sbjct: 469 YYNHPLPDLGAHRQ--TARSFALSGNWYFTPQHKLSLTASHQERLPSTQELYAHGKHVAT 526 Query: 474 STFDIGSSQLKKETSHNIELSLQKTEGLVRWKGN--LFRNKVNNYIYGRTNGQVDDSGAA 531 +TF++G+ L KE S+NIEL+L EG RW+ N L+RN+ NYIY +T + Sbjct: 527 NTFEVGNKHLNKERSNNIELAL-GYEG-DRWQYNLALYRNRFGNYIYAQTLNDGRGPKSI 584 Query: 532 DPNGEFTQRFWSQADATIRGAEAEVSYNWNGE---GMSGRLFADTSRGTLDNL------- 581 + + E ++Q+ A GAE E+ + G+SG D RG L NL Sbjct: 585 EDDSEMKLVRYNQSGADFYGAEGEIYFKPTPRYRIGVSG----DYVRGRLKNLPSLPGRE 640 Query: 582 -------------GNIPLQPATRYGVELGYK-TGPWASGMKVLRAQRQDRLASFETYATP 627 N P PA R G L T + + R Q++LA +ET TP Sbjct: 641 DAYGNRPFIAQDDQNAPRVPAARLGFHLKASLTDRIDANLDYYRVFAQNKLARYET-RTP 699 Query: 628 SYTQVDANLSYTQKLNGVKLTWFALARNLLNQDIRLSTSVLRETVPMGGRNFIVGARTSF 687 + ++ +Y + + W+ A NLLNQ + +S L +T P GR+F G F Sbjct: 700 GHHMLNLGANYRRNTRYGEWNWYVKADNLLNQSVYAHSSFLSDT-PQMGRSFTGGVNVKF 758 >NMA1161 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport NmA Neisseria meningitidis Z2491 Length = 764 Score = 240 bits (613), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 220/718 (30%), Positives = 321/718 (44%), Gaps = 123/718 (17%) Query: 75 KVIAGDELRNKLGNSLGETLSSELGVSASAFGAGASRPIIRGMEGPRVMILQNGMGVSDV 134 K+I+GD LR K N LG+ L G+ AS +G GAS P+IRG G R+ +L + D+ Sbjct: 65 KIISGDTLRQKAVN-LGDALDGVPGIHASQYGGGASAPVIRGQTGRRIKVLNHHGETGDM 123 Query: 135 STVSNDHAVATEAATARQIEILRGPAALLYGSGAIGGLVNVVNDRIPTELVGKPTGTVEG 194 + S DHA+ ++A ++Q+EILRGP LLY SG + GLV+V + +IP ++ P V G Sbjct: 124 ADFSPDHAIMVDSALSQQVEILRGPVTLLYSSGNVAGLVDVADGKIPEKM---PENGVSG 180 Query: 195 RYG----TVDGEKNTS----------FSL----------------------------DTS 212 G + + EK TS F L D+ Sbjct: 181 ELGLRLSSGNLEKLTSGGINIGLGKNFVLHTEGLYRKSGDYAVPRYRNLKRLPDSHADSQ 240 Query: 213 AGQIGLHLDGN-------YRDTSD-YKIPGNARQGDGSTASGRLPNSFTHESSVGLGASY 264 G IGL G Y D D Y +P ++ + D A S ++ + L Sbjct: 241 TGSIGLSWVGEKGFIGAAYSDRRDQYGLPAHSHEYDDCHADIIWQKSLINKRYLQLYPHL 300 Query: 265 VS-----------NWGYVGVSAATLDDHYGIPTSELSFIDLHQNRYDIDTVVNQPFAGIE 313 ++ + G+ A H G P +IDL RY++ QPF G E Sbjct: 301 LTEEDIDYDNPGLSCGFHDDDDAHAHAHNGKP-----WIDLRNKRYELRAEWKQPFPGFE 355 Query: 314 KLRVRLGYTDYTHIEKQRDGTPDTVFSNRAVQTRWELTHAPLAGWHGTFGVQTEQSNYSA 373 LRV L DY H EK D + F+N+ R EL H P+ G++GVQ SA Sbjct: 356 ALRVHLNRNDYRHDEKAGDAV-ENFFNNQTQNARIELRHQPIGRLKGSWGVQYLGQKSSA 414 Query: 374 LSAATGAAE--LTPPTRSTSFAGFLVEERQFGQVLASAGLRGES--VSRRPDAGRQGRD- 428 LSA + A + + + ++ F VE+ + G+R E S R D R+ Sbjct: 415 LSATSEAVKQPMLLDNKVQHYSFFGVEQANWDNFTLEGGVRVEKQKASIRYDKALIDREN 474 Query: 429 -FN------------LLSWSTGALWTFQPGYGLGLTYSLAQRAPTVEELYSNGPHESTST 475 +N S++ W F P + L LT S +R P+ +ELY++G H +T+T Sbjct: 475 YYNHPLPDLGAHRQTARSFALSGNWYFTPQHKLSLTASHQERLPSTQELYAHGKHVATNT 534 Query: 476 FDIGSSQLKKETSHNIELSLQKTEGLVRWKGN--LFRNKVNNYIYGRTNGQVDDSGAADP 533 F++G+ L KE S+NIEL+L EG RW+ N L+RN+ NYIY +T + + Sbjct: 535 FEVGNKHLNKERSNNIELAL-GYEG-DRWQYNLALYRNRFGNYIYAQTLNDGRGPKSIED 592 Query: 534 NGEFTQRFWSQADATIRGAEAEVSYNWNGE---GMSGRLFADTSRGTLDNL--------- 581 + E ++Q+ A GAE E+ + G+SG D RG L NL Sbjct: 593 DSEMKLVRYNQSGADFYGAEGEIYFKPTPRYRIGVSG----DYVRGRLKNLPSLPGREDA 648 Query: 582 -GNIPL----------QPATRYGVELGYK-TGPWASGMKVLRAQRQDRLASFETYATPSY 629 GN PL PA R GV L T + + R Q++LA +ET TP + Sbjct: 649 YGNRPLIAQADQNAPRVPAARLGVHLKASLTDRIDANLDYYRVFAQNKLARYET-RTPGH 707 Query: 630 TQVDANLSYTQKLNGVKLTWFALARNLLNQDIRLSTSVLRETVPMGGRNFIVGARTSF 687 ++ +Y + + W+ A NLLNQ + +S L +T P GR+F G F Sbjct: 708 HMLNLGANYRRNTRYGEWNWYVKADNLLNQSVYAHSSFLSDT-PQMGRSFTGGVNVKF 764