BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0130.p (438 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMa1447 [GEPR] COG0477 Permeases of the major facilitator superf... 470 e-132 AGc4107 [GEPR] COG0477 Permeases of the major facilitator superf... 469 e-132 BMEII0740 [GEPR] COG0477 Permeases of the major facilitator supe... 469 e-132 DRA0271 [GEPR] COG0477 Permeases of the major facilitator superf... 332 1e-90 Cgl2919 [GEPR] COG0477 Permeases of the major facilitator superf... 243 6e-64 >SMa1447 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 450 Score = 470 bits (1209), Expect = e-132, Method: Compositional matrix adjust. Identities = 253/446 (56%), Positives = 319/446 (71%), Gaps = 19/446 (4%) Query: 1 MSTLPASVEQGLQAAGVGKFQYRLFVIFGLVWLADAMQVLSIGFSAPTIAKTFGLTVPQA 60 M+T+ +V+ L AG G +Q RL IFGLVW ADAMQVL++GF+A +IA TFGLTVPQA Sbjct: 14 MTTI--TVDDALDRAGTGTYQRRLMAIFGLVWAADAMQVLAVGFTAASIAATFGLTVPQA 71 Query: 61 LQTGTMFFVGMLLGAFVFGRLADRIGRRPVLMGAVVIDACFGVASAFAPDFTWLLALRLL 120 LQTGT+FF+GML GA FGRLADRIGRR VL+ V DA FG+ S FA DFT LL LR L Sbjct: 72 LQTGTLFFLGMLFGAAGFGRLADRIGRRRVLIATVACDAVFGLLSVFAQDFTVLLLLRFL 131 Query: 121 TGIGVGGTLPVDYTMMAEFLPSARRGRWLVMLESFWAIGTICLAVLALVAVSWG-NDAWR 179 TG VGGTLPVDY MMAEFLP+ RGRWLVMLE FWA+GT+ +A+ A A G DAWR Sbjct: 132 TGAAVGGTLPVDYAMMAEFLPARNRGRWLVMLEGFWAVGTLIVALAAWAASLAGVADAWR 191 Query: 180 VIFFVTGLPALVGVVLRFYVPESPMYLNRSGKSDAARLVLERVAKVNG--------SSTP 231 IF VT +PAL+GV LRF VPESP+YL R GK+ A+ +++ + VNG S P Sbjct: 192 YIFAVTAIPALIGVGLRFLVPESPLYLLRLGKTSEAKAIVDEILVVNGKMRLGAGASLVP 251 Query: 232 IPPLQPEVVERKPMSALFSAALRRRSLSLYLAWGLISIAYYGVFVYLPVKLGSEGFGFMR 291 PP + +FSA LR+RSL + W L+SI+YYGVF ++P +L EGFGF+R Sbjct: 252 PPP--------TASAGIFSADLRKRSLMILAIWFLVSISYYGVFTWMPPRLAGEGFGFVR 303 Query: 292 GQIFLIFLALVQLPGYALSAYGVERWGRKPTLVGFLVLSAVGCMLYSLGKDPMLVVGSTL 351 G FL+ LAL Q+PGYAL+AYGVE+WGR+PTL+GF +LSA+GC+L+ ML+ S L Sbjct: 304 GYGFLVVLALAQIPGYALAAYGVEKWGRRPTLIGFCLLSALGCLLFVAAGTAMLIGVSLL 363 Query: 352 LLSFSLLGTWAALYAFTPEVYPTDLRASGMGTAGAVARFGGLFAPAIVAPVMASHFTLAL 411 ++SF+LLGTW ALYA+TPE+YPT RA+GMG AGA+AR GGL AP+++ V+A F LA+ Sbjct: 364 IMSFALLGTWGALYAYTPELYPTASRATGMGAAGAMARLGGLLAPSLMGLVVAQSFGLAI 423 Query: 412 AMLSAFLVAGAVAILCVDVESRNRAL 437 + + L+ AVA +D E+R +L Sbjct: 424 GIFAGLLLVAAVAAFLIDAETRRVSL 449 >AGc4107 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 437 Score = 469 bits (1208), Expect = e-132, Method: Compositional matrix adjust. Identities = 245/436 (56%), Positives = 319/436 (73%), Gaps = 9/436 (2%) Query: 7 SVEQGLQAAGVGKFQYRLFVIFGLVWLADAMQVLSIGFSAPTIAKTFGLTVPQALQTGTM 66 ++ L+ AG G +Q RL IFGLVW ADAMQVL++GF+A +IA TFGLTVPQALQTGT Sbjct: 5 TMNDALERAGAGAYQRRLMGIFGLVWAADAMQVLAVGFTAASIAATFGLTVPQALQTGTA 64 Query: 67 FFVGMLLGAFVFGRLADRIGRRPVLMGAVVIDACFGVASAFAPDFTWLLALRLLTGIGVG 126 FF GMLLGA FGRLADR GRR VL+ V DA FGV S F+PDFT LL LR LTG VG Sbjct: 65 FFFGMLLGAAGFGRLADRYGRRRVLIVTVACDALFGVLSIFSPDFTILLVLRFLTGAAVG 124 Query: 127 GTLPVDYTMMAEFLPSARRGRWLVMLESFWAIGTICLAVLALVAVSWG-NDAWRVIFFVT 185 GTLPVDY MMAEFLP+ RGRWLV LE FWA+GT+ +A+ A A G DAWR IF VT Sbjct: 125 GTLPVDYAMMAEFLPAKNRGRWLVFLEGFWAVGTLIVALAAWGASLAGVADAWRYIFAVT 184 Query: 186 GLPALVGVVLRFYVPESPMYLNRSGKSDAARLVLERVAKVNGSSTPIPP----LQPEVVE 241 PA++G+ LRF VPESP+YL R+G+S+ A+ V+ R+ VNG + P+ QP+V + Sbjct: 185 AFPAVLGLGLRFLVPESPLYLLRTGRSEEAKAVVNRMLVVNGRA-PLDAGTGLFQPDVTK 243 Query: 242 RKPMSALFSAALRRRSLSLYLAWGLISIAYYGVFVYLPVKLGSEGFGFMRGQIFLIFLAL 301 + +FS ALR+RS+ + W L+S++YYGVF ++P KL +GFGF+RG FL+ +AL Sbjct: 244 GQ---GIFSPALRQRSMMILAIWFLVSVSYYGVFTWMPAKLAGDGFGFVRGYGFLVLVAL 300 Query: 302 VQLPGYALSAYGVERWGRKPTLVGFLVLSAVGCMLYSLGKDPMLVVGSTLLLSFSLLGTW 361 Q+PGYA++AYGVE+WGRKPTL+GF +LSA+GC+L++L ++ S L++SF+LLGTW Sbjct: 301 AQIPGYAIAAYGVEKWGRKPTLIGFCLLSALGCLLFTLASAGAMIAASLLIMSFALLGTW 360 Query: 362 AALYAFTPEVYPTDLRASGMGTAGAVARFGGLFAPAIVAPVMASHFTLALAMLSAFLVAG 421 ALYAFTPE+YPT+ RA+GMG AGA+AR GGL AP+++ +A F +A+ + + LV Sbjct: 361 GALYAFTPELYPTESRATGMGAAGAMARLGGLLAPSLLGYAIAQGFGVAIGIFAGLLVLA 420 Query: 422 AVAILCVDVESRNRAL 437 A+A ++ E+R AL Sbjct: 421 AIAATMINAETRQVAL 436 >BMEII0740 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 448 Score = 469 bits (1206), Expect = e-132, Method: Compositional matrix adjust. Identities = 245/437 (56%), Positives = 314/437 (71%), Gaps = 9/437 (2%) Query: 7 SVEQGLQAAGVGKFQYRLFVIFGLVWLADAMQVLSIGFSAPTIAKTFGLTVPQALQTGTM 66 ++E+ L AG G FQ L IFGLVW ADAMQVL++GF+ IAKTFGLTVPQALQTGT+ Sbjct: 16 TIEETLDQAGTGSFQRGLLGIFGLVWAADAMQVLAVGFTGAAIAKTFGLTVPQALQTGTL 75 Query: 67 FFVGMLLGAFVFGRLADRIGRRPVLMGAVVIDACFGVASAFAPDFTWLLALRLLTGIGVG 126 FF+GML+GA +FGRLAD+ GRR +L+ V DA FG+ SAFAPDF LLALR LTG+ VG Sbjct: 76 FFLGMLVGAALFGRLADKYGRRRILLITVACDALFGLLSAFAPDFGSLLALRFLTGLAVG 135 Query: 127 GTLPVDYTMMAEFLPSARRGRWLVMLESFWAIGTICLAVLA-LVAVSWGNDAWRVIFFVT 185 GTLPVDY MMAEFLP+ RGRWLVMLE FWA+GT+ +A+ A +V+ DAWR IF VT Sbjct: 136 GTLPVDYAMMAEFLPAKNRGRWLVMLEGFWAVGTVVIAIAAWATSVAGVEDAWRYIFIVT 195 Query: 186 GLPALVGVVLRFYVPESPMYLNRSGKSDAARLVLERVAKVNGSSTPIPP----LQPEVVE 241 PAL+G+ LRF VPESPM+L +SG+ + A+ V+ V NG +PP L P +V Sbjct: 196 AAPALIGIWLRFRVPESPMHLLKSGRVEEAKAVINLVLSRNGKP-ELPPGAKLLAPRLVT 254 Query: 242 RKPMSALFSAALRRRSLSLYLAWGLISIAYYGVFVYLPVKLGSEGFGFMRGQIFLIFLAL 301 + L S LR+R+L+ W L+S++YYG+F ++P KL S+GFGF+RG FL+ +AL Sbjct: 255 NER---LLSPNLRQRTLTSLAIWFLVSVSYYGIFTWIPAKLASDGFGFVRGYGFLVVVAL 311 Query: 302 VQLPGYALSAYGVERWGRKPTLVGFLVLSAVGCMLYSLGKDPMLVVGSTLLLSFSLLGTW 361 QLPGYAL+AYGVE WGR+ TL+GFL +SA C L+++ +V S L++SF+LLGTW Sbjct: 312 AQLPGYALAAYGVEAWGRRKTLIGFLFVSAAACALFTVATSSSVVGASILIMSFALLGTW 371 Query: 362 AALYAFTPEVYPTDLRASGMGTAGAVARFGGLFAPAIVAPVMASHFTLALAMLSAFLVAG 421 ALYAFTPE+YPT LRASGMG AGA+AR GGL AP+ +A V+ F A+AM + L Sbjct: 372 GALYAFTPELYPTALRASGMGAAGAMARLGGLLAPSAMAVVINQSFYTAVAMFAGLLALA 431 Query: 422 AVAILCVDVESRNRALE 438 + ++VE+R +AL Sbjct: 432 GIIAFFINVETRQQALN 448 >DRA0271 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 454 Score = 332 bits (851), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 197/441 (44%), Positives = 275/441 (62%), Gaps = 5/441 (1%) Query: 2 STLPASVEQGLQAAGVGKFQYRLFVIFGLVWLADAMQVLSIGFSAPTIAKTFGLT--VPQ 59 ++P +V++ L G+G+FQ++L I GL W ADAM+VL +GF+ P I+ F L P Sbjct: 9 KSVPMTVDRVLDDLGLGRFQWKLLAICGLTWAADAMEVLLMGFALPGISAAFELPKGSPA 68 Query: 60 ALQTGTMFFVGMLLGAFVFGRLADRIGRRPVLMGAVVIDACFGVASAFAPDFTWLLALRL 119 A T F GML GA+ +G LADR+GRR V + V + FG+A A AP TWLL R Sbjct: 69 ATMLLTATFAGMLFGAWFWGYLADRVGRRSVFLTTVALGVVFGLAGALAPTLTWLLVARF 128 Query: 120 LTGIGVGGTLPVDYTMMAEFLPSARRGRWLVMLESFWAIGTICLAVLA-LVAVSWG-NDA 177 LTG +GGTLPVDY+MMAEF+P+A RGR+LV LESFWA+GT+ +A LA V+ ++ + Sbjct: 129 LTGFAIGGTLPVDYSMMAEFVPTAWRGRFLVYLESFWAVGTVVVAALAWWVSTAFAPAEG 188 Query: 178 WRVIFFVTGLPALVGVVLRFYVPESPMYLNRSGKSDAARLVLERVAKVNGSSTPIPPL-Q 236 WR + + LP LVG++ R +P+SP L G+ AR L++VA+ NG + P PL Sbjct: 189 WRWLLGLAALPGLVGLIARIGIPDSPRSLLARGEEAQARAALQKVAQANGGTLPAAPLAH 248 Query: 237 PEVVERKPMSALFSAALRRRSLSLYLAWGLISIAYYGVFVYLPVKLGSEGFGFMRGQIFL 296 PE R + LF L RR+ L + W +S+ YYG+F +LP L ++G Sbjct: 249 PEQPPRVSPAQLFRGVLARRTPLLMVTWFGLSLGYYGIFSWLPSFLRAQGLDLGAVYRST 308 Query: 297 IFLALVQLPGYALSAYGVERWGRKPTLVGFLVLSAVGCMLYSLGKDPMLVVGSTLLLSFS 356 + LAL Q+PGY L+AY VE+ GR+ TLVGFL L AVG L+ L D V+ ++ LLSF+ Sbjct: 309 LLLALAQVPGYLLAAYLVEKIGRRVTLVGFLTLGAVGAYLFLLAHDANTVLLTSALLSFA 368 Query: 357 LLGTWAALYAFTPEVYPTDLRASGMGTAGAVARFGGLFAPAIVAPVMASHFTLALAMLSA 416 LLG W +LYA+TPE++PT LR +GMG VAR + +P+I A ++ + TLAL + + Sbjct: 369 LLGAWGSLYAYTPELFPTPLRTTGMGLVSGVARLASVVSPSIGAMLLTGNLTLALTVFAV 428 Query: 417 FLVAGAVAILCVDVESRNRAL 437 A+A + VE+R +AL Sbjct: 429 CFALAALAAWGIGVETRGQAL 449 >Cgl2919 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 439 Score = 243 bits (620), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 139/379 (36%), Positives = 220/379 (58%), Gaps = 3/379 (0%) Query: 29 GLVWLADAMQVLSIGFSAPTIAKTFGLTVPQALQTGTMFFVGMLLGAFVFGRLADRIGRR 88 G+ W DAM V I F +A +GL+ + G++ FVGM +GA + G LAD++GRR Sbjct: 26 GIGWALDAMDVGLISFVMAALATHWGLSPTETSLLGSIGFVGMAIGASLGGLLADKLGRR 85 Query: 89 PVLMGAVVIDACFGVASAFAPDFTWLLALRLLTGIGVGGTLPVDYTMMAEFLPSARRGRW 148 V ++++ ASA + L+ALR + G+G+G LPV T+++EF P RGR Sbjct: 86 QVFALSLLVYGVATGASALSVSLAMLMALRFVVGLGLGAELPVASTLISEFSPRKVRGRM 145 Query: 149 LVMLESFWAIGTICLAVLALVAVSWGNDAWRVIFFVTGLPALVGVVLRFYVPESPMYLNR 208 +V+LE+FWA+G I A++ V+ ++ WR + +PA+ V +R +PES +L + Sbjct: 146 VVILEAFWALGWIMAAIVGTFVVAGSDNGWRWALALGCVPAIYAVYVRLGLPESVRFLEK 205 Query: 209 SGKSDAARLVLERVAKVNGSSTPIPPLQPEVVERKPMS---ALFSAALRRRSLSLYLAWG 265 G+ D A ++ + + VV +++SAALR+R+++L++ W Sbjct: 206 KGRHDEAEAIVVSFEEAAAAEGKAADATTAVVHDNAAEGSVSIWSAALRKRTVALWIVWF 265 Query: 266 LISIAYYGVFVYLPVKLGSEGFGFMRGQIFLIFLALVQLPGYALSAYGVERWGRKPTLVG 325 I+++YYG F+++P L ++GF ++ F + + L QLPGYA++A+ +E+WGR+ TL Sbjct: 266 CINLSYYGAFIWIPSLLVADGFTLVKSFQFTLIITLAQLPGYAVAAWLIEKWGRRSTLAT 325 Query: 326 FLVLSAVGCMLYSLGKDPMLVVGSTLLLSFSLLGTWAALYAFTPEVYPTDLRASGMGTAG 385 FLV SA+ LY L ++ + LLSF LG W ALYA PE+YPT++R +G G A Sbjct: 326 FLVGSAISAALYGLANVEWQILVAGCLLSFFNLGAWGALYAIGPELYPTNVRGTGTGAAA 385 Query: 386 AVARFGGLFAPAIVAPVMA 404 R + AP IV PV+A Sbjct: 386 GFGRIASIIAPLIVPPVIA 404