BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0036.p (260 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr2400 [IQR] COG1028 Dehydrogenases with different specificitie... 367 e-101 RSp1059 [IQR] COG1028 Dehydrogenases with different specificitie... 333 2e-91 SMb21010 [IQR] COG1028 Dehydrogenases with different specificiti... 188 1e-47 AGc4198 [IQR] COG1028 Dehydrogenases with different specificitie... 184 2e-46 BMEI0268 [IQR] COG1028 Dehydrogenases with different specificiti... 175 8e-44 >mlr2400 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 256 Score = 367 bits (943), Expect = e-101, Method: Compositional matrix adjust. Identities = 172/256 (67%), Positives = 213/256 (83%), Gaps = 1/256 (0%) Query: 5 DKVALITGSASGIGKEIAVEYARQGAKVVIADLALEAAKATAEEIVKEGGTAMAVAMNVT 64 DKV ++TG+ASGIGKEIA+ +AR+GAKVVIADL L+AA+ TA EI A+ V M+V+ Sbjct: 2 DKVVVVTGAASGIGKEIALTFARKGAKVVIADLDLDAAEETAREIDPAALRALGVGMDVS 61 Query: 65 DETQVDKGVADAVNTYGGLDIMISNAGIQIISPVAELSLENWRKMLAIHLDGAFLTTRAA 124 +E QV+ G++ V T+G +D+++SNAG+Q ++P+ E + WRK+L+IHLDGAFLTTRAA Sbjct: 62 NEDQVESGISRVVETFGRIDVLVSNAGVQTVAPLVEFDFDKWRKLLSIHLDGAFLTTRAA 121 Query: 125 MKAMIKQGRGGSIIYMGSVHSHLASPLKAPYVTAKHGLLGLAKTVAKEGAKDKIRTNVIC 184 ++ M +Q GSIIYMGSVHS ASP KAPYVTAKHGL+GLAK VAKEGA +R NVIC Sbjct: 122 LRQMYRQN-SGSIIYMGSVHSKEASPFKAPYVTAKHGLIGLAKVVAKEGAAHGVRANVIC 180 Query: 185 PGFVRTPLVEKQIPEQAKEFGISEEDVIKKIMLKDTVDGEFTTTQDVAQTAVFLAAFPTN 244 PGFVRTPLVEKQIPEQA+E GIS EDV+K +ML++TVDGEFTT QDVA+TA+FLAAFP+N Sbjct: 181 PGFVRTPLVEKQIPEQARELGISPEDVVKTMMLRETVDGEFTTVQDVAETALFLAAFPSN 240 Query: 245 ALTGQSVVVSHGWHMQ 260 ALTGQS+VVSHGW MQ Sbjct: 241 ALTGQSIVVSHGWFMQ 256 >RSp1059 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 261 Score = 333 bits (855), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 159/258 (61%), Positives = 200/258 (77%) Query: 3 LKDKVALITGSASGIGKEIAVEYARQGAKVVIADLALEAAKATAEEIVKEGGTAMAVAMN 62 LK KVA++TG+ASGIGK+IA+ AR GA + I DL + A+A A+EI GG A+ + M+ Sbjct: 4 LKGKVAVVTGAASGIGKQIALTLARAGAAIGIVDLNEDGAQAAAKEITDAGGKAIGLRMD 63 Query: 63 VTDETQVDKGVADAVNTYGGLDIMISNAGIQIISPVAELSLENWRKMLAIHLDGAFLTTR 122 VTDE VD G+ G +DI++SNAG+QI++P+ + +W+KM AIH+DGAFLTTR Sbjct: 64 VTDEQAVDIGIDRVAAELGSVDILVSNAGVQIVNPIESYAFADWKKMQAIHVDGAFLTTR 123 Query: 123 AAMKAMIKQGRGGSIIYMGSVHSHLASPLKAPYVTAKHGLLGLAKTVAKEGAKDKIRTNV 182 AA++ M K RGG +IYMGSVHSH SPLK+ YV AKH LLGL+K +AKEGA +R++V Sbjct: 124 AALRHMYKDKRGGVVIYMGSVHSHEGSPLKSAYVAAKHALLGLSKVLAKEGAAHNVRSHV 183 Query: 183 ICPGFVRTPLVEKQIPEQAKEFGISEEDVIKKIMLKDTVDGEFTTTQDVAQTAVFLAAFP 242 +CPGFVRTPLV+KQIPEQAKE GISEEDV+KK+ML TVDG FTT +DVA+T FLA+FP Sbjct: 184 VCPGFVRTPLVDKQIPEQAKELGISEEDVVKKVMLGGTVDGVFTTVEDVAETVRFLASFP 243 Query: 243 TNALTGQSVVVSHGWHMQ 260 + ALTGQS VVSHGW MQ Sbjct: 244 SAALTGQSFVVSHGWFMQ 261 >SMb21010 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 258 Score = 188 bits (477), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 103/257 (40%), Positives = 155/257 (60%), Gaps = 3/257 (1%) Query: 6 KVALITGSASGIGKEIAVEYARQGAKVVIADL-ALEAAKATAEEIVK-EGGTAMAVAMNV 63 K A+ITGS SGIG IA A+ GA +V+ A + + +E+ GT + ++ Sbjct: 3 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADM 62 Query: 64 TDETQVDKGVADAVNTYGGLDIMISNAGIQIISPVAELSLENWRKMLAIHLDGAFLTTRA 123 T +++ +A + +GG DI+++NAG+Q + + + +E W +++A++L +F T R Sbjct: 63 TKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRG 122 Query: 124 AMKAMIKQGRGGSIIYMGSVHSHLASPLKAPYVTAKHGLLGLAKTVAKEGAKDKIRTNVI 183 A+ M K+G G II + S H +ASP K+ YV AKHG++GL KTVA E A+ + N I Sbjct: 123 AIPPMKKKGWG-RIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNSI 181 Query: 184 CPGFVRTPLVEKQIPEQAKEFGISEEDVIKKIMLKDTVDGEFTTTQDVAQTAVFLAAFPT 243 CPG+V TPLVEKQIP+QA+ GI+EE VI ++MLK +F T + VA A++LA Sbjct: 182 CPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGDDA 241 Query: 244 NALTGQSVVVSHGWHMQ 260 +TG V + GW Q Sbjct: 242 AQITGTHVSMDGGWTAQ 258 >AGc4198 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 305 Score = 184 bits (467), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 106/259 (40%), Positives = 151/259 (58%), Gaps = 7/259 (2%) Query: 6 KVALITGSASGIGKEIAVEYARQGAKVVIA----DLALEAAKATAEEIVKEGGTAMAVAM 61 + ++TGS SGIG IA +AR+GA +V+ D +E + E + GG + Sbjct: 50 RTVIVTGSTSGIGLGIAQRFAREGANIVLNGFGDDDEIEKLRLLLE--AESGGRVLYHPA 107 Query: 62 NVTDETQVDKGVADAVNTYGGLDIMISNAGIQIISPVAELSLENWRKMLAIHLDGAFLTT 121 ++T ++ + + G +D++I+NAGIQ I+P+ E E W ++AI+L +F T Sbjct: 108 DMTKPDEIADLIQSSHEKLGSVDVLINNAGIQHIAPIEEFPTEKWDWIIAINLTSSFHTM 167 Query: 122 RAAMKAMIKQGRGGSIIYMGSVHSHLASPLKAPYVTAKHGLLGLAKTVAKEGAKDKIRTN 181 RAA+ M K G+G II + S H +ASP K+ YV AKHG++GL KT A E A+ + N Sbjct: 168 RAAIPLMKKAGKG-RIINISSAHGLVASPFKSAYVAAKHGIMGLTKTAALELAQTGVTVN 226 Query: 182 VICPGFVRTPLVEKQIPEQAKEFGISEEDVIKKIMLKDTVDGEFTTTQDVAQTAVFLAAF 241 ICPG+V TPLVEKQIPE AK GISE V +ML+ +F T DVA A+FLA+ Sbjct: 227 AICPGYVLTPLVEKQIPEMAKVRGISEAAVKNDVMLELQATKQFVTVDDVAAAAIFLASD 286 Query: 242 PTNALTGQSVVVSHGWHMQ 260 + +TG + V GW Q Sbjct: 287 AASNITGTHISVDGGWTAQ 305 >BMEI0268 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bme Brucella melitensis Length = 271 Score = 175 bits (444), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 107/259 (41%), Positives = 144/259 (55%), Gaps = 13/259 (5%) Query: 6 KVALITGSASGIGKEIAVEYARQGAKVVI-------ADLALEAAKATAEEIVKEGGTAMA 58 K A++TGS SGIG IA A G VVI D AL A+ AEE G + Sbjct: 16 KTAIVTGSNSGIGLGIAHALAAAGHNVVINSFTDRDEDHAL--ARMLAEE---HGANVIY 70 Query: 59 VAMNVTDETQVDKGVADAVNTYGGLDIMISNAGIQIISPVAELSLENWRKMLAIHLDGAF 118 +A +++ +A V +G DI+++NAGIQ ++PV E E W +++AI+L AF Sbjct: 71 IAADMSKAEDCRNLIAKTVKVFGNSDILVNNAGIQHVAPVEEFPPEQWDRIIAINLTSAF 130 Query: 119 LTTRAAMKAMIKQGRGGSIIYMGSVHSHLASPLKAPYVTAKHGLLGLAKTVAKEGAKDKI 178 T+ AA+ M K G G II + S H +ASP K+ YV AKHG++G KT+A E A KI Sbjct: 131 HTSAAAIPHMRKAG-WGRIINIASAHGLVASPFKSAYVAAKHGIVGFTKTLALELATAKI 189 Query: 179 RTNVICPGFVRTPLVEKQIPEQAKEFGISEEDVIKKIMLKDTVDGEFTTTQDVAQTAVFL 238 N ICPG+V TPLVE QIP+Q K + E VI+ +ML EF TT + A FL Sbjct: 190 TANSICPGYVLTPLVEAQIPDQMKAHHMDRETVIRDVMLDKQPTKEFVTTAQIGAVATFL 249 Query: 239 AAFPTNALTGQSVVVSHGW 257 A+ + G ++ V GW Sbjct: 250 ASDAAAQINGAAISVDGGW 268