BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0030.p (308 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc2648 [GER] COG0697 Permeases of the drug/metabolite transport... 348 1e-95 CC0848 [GER] COG0697 Permeases of the drug/metabolite transporte... 233 3e-61 RSc0233 [GER] COG0697 Permeases of the drug/metabolite transport... 217 3e-56 RSc1428 [GER] COG0697 Permeases of the drug/metabolite transport... 203 3e-52 STM4400 [GER] COG0697 Permeases of the drug/metabolite transport... 149 5e-36 >AGc2648 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 310 Score = 348 bits (892), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 172/300 (57%), Positives = 222/300 (74%) Query: 5 GILYSALAGAAWGLVFLAPELTRSFSPWQLTAGRYLAYGLFAGVLIAPRLRRLLPHLGRD 64 G+ Y LAGA WG +FLAP+L FS QL+ RYL YGL + ++I PRL+R+ H G Sbjct: 8 GVFYGMLAGALWGGIFLAPKLVPDFSALQLSTARYLTYGLISLIIIGPRLKRVSAHFGAR 67 Query: 65 EWRALVWLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGEGAVPLRKLV 124 EW AL WLS++GN+ YYVF+++AV+L G+A TS++IGFLPVAV+IIGSR GAV L++L Sbjct: 68 EWIALGWLSMIGNIAYYVFISTAVKLSGVAFTSIIIGFLPVAVTIIGSRDHGAVSLKRLW 127 Query: 125 PSLALGLAGIACVAWQSLSVSTAGQARDSVIGFFCALAALISWTTYAVGNSRWLARLHHI 184 PSLA G GI ++WQSL+ + AG +IG AL AL SWT +AVGN+RWL+RLH + Sbjct: 128 PSLAFGAIGIVGISWQSLTENDAGLDVSRLIGLASALGALASWTAFAVGNARWLSRLHDV 187 Query: 185 SAHDWNLLIGVVTGLLSLFVAVPAFTVMLQPHPGHDWLHFAAVSAGVAICASLFGNACWN 244 SA DWN++ GVVTG L+L +A+PAF + H DWLHFAA++AG+ AS+ GNA WN Sbjct: 188 SADDWNMMTGVVTGGLALLLAIPAFGFGGESHSSGDWLHFAAIAAGLGFTASILGNAFWN 247 Query: 245 KASRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTASVLLCVSAHRIDE 304 + SR+LPLTM+GQMILFETLFALLYGFLWE PT +EI A+ V SV+LC+ AHR ++ Sbjct: 248 RMSRMLPLTMVGQMILFETLFALLYGFLWEGHGPTFVEIVAICSVVLSVVLCMRAHRPEK 307 >CC0848 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ccr Caulobacter vibrioides Length = 312 Score = 233 bits (595), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 147/291 (50%), Positives = 190/291 (65%) Query: 11 LAGAAWGLVFLAPELTRSFSPWQLTAGRYLAYGLFAGVLIAPRLRRLLPHLGRDEWRALV 70 +AGA WG VFLAP+L F+P Q TAGRYLAYGL A VL+AP + ++ + +WR L+ Sbjct: 16 IAGAFWGGVFLAPKLLADFTPLQATAGRYLAYGLAAAVLLAPSWKAVMARMDGRDWRDLL 75 Query: 71 WLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGEGAVPLRKLVPSLALG 130 LSLLGN++YYV LA AVQ G+A+ SLVIG LPV ++++G++ PLR+LV LAL Sbjct: 76 LLSLLGNLIYYVGLAIAVQSAGVALASLVIGLLPVTITLVGAKAGEGTPLRRLVWPLALI 135 Query: 131 LAGIACVAWQSLSVSTAGQARDSVIGFFCALAALISWTTYAVGNSRWLARLHHISAHDWN 190 +AG C+ + + + +++G AL AL WT YAV N+R LA ++H+W+ Sbjct: 136 VAGGVCINLDAFAAAGRAGMSKTLVGLLGALLALAVWTAYAVWNARRLAATPKFNSHEWS 195 Query: 191 LLIGVVTGLLSLFVAVPAFTVMLQPHPGHDWLHFAAVSAGVAICASLFGNACWNKASRLL 250 LL GV TGLLSL + VPAF + H W F VS VAI AS+ GN WN ASRLL Sbjct: 196 LLTGVATGLLSLVIVVPAFAFDGKTHAAGAWGLFWGVSFAVAIGASVIGNGLWNAASRLL 255 Query: 251 PLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTASVLLCVSAHR 301 PL++ GQ+I+FET+FALLYGFL E RWP LE AM L+ A VL HR Sbjct: 256 PLSLSGQLIVFETVFALLYGFLHEGRWPRSLESVAMALMLAGVLWSARLHR 306 >RSc0233 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 326 Score = 217 bits (553), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 132/293 (45%), Positives = 181/293 (61%), Gaps = 4/293 (1%) Query: 12 AGAAWGLVFLAPELTRSFSPWQLTAGRYLAYGLFAGVLIAPRLRRLLPHLGRDEWRALVW 71 AGA WG++F+AP + +FSP L+A RYL YG+ + L P R L R +W ALV Sbjct: 33 AGALWGIIFVAPRMLPAFSPLALSAARYLLYGVLSLALALPVWRPLWRKTTRRDWLALVL 92 Query: 72 LSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGEGAVPLRKLVPSLALGL 131 LSL GNV+YY+ +A VQ G+A SL++G LPV V++ G+ G++PLR+L L + Sbjct: 93 LSLPGNVLYYLCVAGGVQRAGVAPVSLIVGLLPVTVTLAGAAEHGSLPLRRLALPLLMAA 152 Query: 132 AGIACVAWQSLSVSTAGQARDSVIGFFCALAALISWTTYAVGNSRWLARLHHISAHDWNL 191 AG+AC+ + + ++G A AL WT YAV N+R+L R ++ +W+L Sbjct: 153 AGVACIYADAPATQAGAGGATHLLGLLMAAGALACWTVYAVCNARYLRRHPQFTSREWSL 212 Query: 192 LIGVVTGLLSLFVAVPAFTV----MLQPHPGHDWLHFAAVSAGVAICASLFGNACWNKAS 247 L G+ TG LSL +AVPAF + P P W F V+ GVA+ AS+ GN+ WN AS Sbjct: 213 LTGIATGALSLVLAVPAFLMPGMATAAPQPASAWGLFWLVNTGVALGASVLGNSLWNTAS 272 Query: 248 RLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTASVLLCVSAH 300 R LPLT+ GQMI+FET+FALLYGF+ E RWP LE+AA +L+ + V L H Sbjct: 273 RKLPLTLSGQMIVFETVFALLYGFIQEGRWPHGLEVAAALLLMSGVGLAARRH 325 >RSc1428 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 313 Score = 203 bits (517), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 142/308 (46%), Positives = 183/308 (59%), Gaps = 8/308 (2%) Query: 5 GILYSALAGAAWGLVFLAPELTRSFSPWQLTAGRYLAYGLFAGVLIAPRLRRLLPHLGRD 64 G+L + LAGA WG+VF+AP +FSPW+L GRYLAYG A + AP L R+ L R Sbjct: 4 GVLCALLAGAMWGMVFIAPRALPAFSPWELALGRYLAYGAIAALAAAPILPRIARKLTRA 63 Query: 65 EWRALVWLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGEGAVPLRKLV 124 + AL+ + GN+VYYV LA VQL G+A SL+IG LP+ V+++G R GAVPL +L Sbjct: 64 DCLALMRQACSGNLVYYVLLAFGVQLAGVAPVSLIIGVLPITVTVLGRRDHGAVPLSRLA 123 Query: 125 PSLALGLAGIACVAWQ--SLSVSTAGQAR---DSVIGFFCALAALISWTTYAVGNSRWLA 179 L + AGIAC+ S AG A + G CA AL SWT YA+ N+R L Sbjct: 124 WPLLVVAAGIACINIDLFSHDAVAAGDAHPIWSRIAGIACAAGALCSWTWYAIDNARHLQ 183 Query: 180 RLHHISAHDWNLLIGVVTGLLSLFVAVPAFTVML---QPHPGHDWLHFAAVSAGVAICAS 236 R H S+++W+ L G+ TG LS + A G W F AV+A VA+ AS Sbjct: 184 RNPHFSSNEWSALYGISTGALSAALTAAAVLAAGTGWAEGGGRVWTTFWAVNAAVALGAS 243 Query: 237 LFGNACWNKASRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTASVLLC 296 L GN WN A+R LPLT+ GQMI+FETLFAL YGF+++ RWP LE+AA+ L+ V Sbjct: 244 LIGNNLWNIAARRLPLTLSGQMIVFETLFALAYGFVYDHRWPRPLEMAAIALLIVGVGWS 303 Query: 297 VSAHRIDE 304 V H D Sbjct: 304 VRLHADDN 311 >STM4400 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 321 Score = 149 bits (377), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 110/316 (34%), Positives = 163/316 (51%), Gaps = 24/316 (7%) Query: 2 ILQGILYSALAGAAWGLVFLAPELTRSFSPWQLTAGRYLAYGLFAGVLIAPRLRRLLPHL 61 ++ G+LY+ LAG WGL+F+ P + + + GRYLA GL A + IA R L L Sbjct: 1 MISGVLYALLAGLMWGLIFVGPLIVPDYPALLQSMGRYLALGLIA-LPIAWLGRTRLRQL 59 Query: 62 GRDEWRALVWLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAV----SIIGSRGEGA 117 R +W + L+L+GNV+YY LASA+Q G +++++IG LPV + +++ S+ +G Sbjct: 60 TRKDWSTALSLTLMGNVIYYACLASAIQRTGAPVSTMIIGTLPVVIPLFANVLYSQRDGR 119 Query: 118 VPLRKLVPSLALGLAGIACVAWQSLS---VSTAGQARDSVIGFFCALAALISWTTYAVGN 174 + R+L P+LAL G+ CV LS +G S G AL ++ W YA+ N Sbjct: 120 LSWRRLAPALALIGFGLLCVNIAELSQGLSDVSGWRYGS--GIVLALISVACWAWYALRN 177 Query: 175 SRWLARLHHISAHDWNL----------LIGVVTGLLSLFVAVPAFTVMLQPHPGHDWLHF 224 +RWL W LIG L L + P FT+ PHP F Sbjct: 178 ARWLRENPDKHPMMWATAQALVTLPVSLIGYAAVCLWLSIQKPLFTLPFGPHPAL----F 233 Query: 225 AAVSAGVAICASLFGNACWNKASRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIA 284 + +A+ S G CWN AS+ LP ++G +I+FETL LLY F+ Q P L ++ Sbjct: 234 IGLMIAIAVLCSWVGALCWNIASQKLPTVILGPLIVFETLAGLLYTFILRQEIPPFLTLS 293 Query: 285 AMVLVTASVLLCVSAH 300 + L+ A V++ V A Sbjct: 294 GIALLVAGVVIAVRAK 309