BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0075.p (400 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 612 e-175 YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 523 e-148 ECs2884 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 510 e-144 yegO [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 509 e-144 ZyegO [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 504 e-142 >RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1033 Score = 612 bits (1578), Expect = e-175, Method: Compositional matrix adjust. Identities = 293/396 (73%), Positives = 352/396 (88%) Query: 1 MNISLPFIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMA 60 MN+S FI RP+AT LLTIG+ALAGI AF LLPVSPLPQVD+PTIS++AS+PGASPETMA Sbjct: 1 MNLSATFIARPVATALLTIGVALAGIAAFNLLPVSPLPQVDFPTISVNASLPGASPETMA 60 Query: 61 ATVATPLERAMGAIAGVTEMTSTSSQNSTRITLQFDLSRDIDGAARDVQAALNAARNLLP 120 ATVATPLER++G IAG+TEMTS S+ STR+TLQFDLSRDIDGAARDVQAA+NA+R+LLP Sbjct: 61 ATVATPLERSLGRIAGITEMTSQSALGSTRVTLQFDLSRDIDGAARDVQAAINASRSLLP 120 Query: 121 TGMPSNPTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGS 180 +G+PSNPTYRKVNPADAPI+IL +TSDT ++G++YDAA +I+AQKLSQ+ GVGQV++GG+ Sbjct: 121 SGLPSNPTYRKVNPADAPIMILGLTSDTKSRGELYDAASTILAQKLSQITGVGQVNIGGA 180 Query: 181 SQPAVRIELNPTALNKYGIGTADVRTAVAATNANRPKGLLEDQDRNWQIYANDQAKTAAE 240 S PAVR+ELNPTALNKYGI T VRT + ATNAN+PKG+LE +R W +YANDQA+ A E Sbjct: 181 SLPAVRVELNPTALNKYGISTETVRTVITATNANKPKGMLEAGNRVWTLYANDQARHAEE 240 Query: 241 YAPLIVSYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIDTVDNV 300 Y PLI++YRNG PVR+ DVAEV DSV D+RN GS+NGKPSVL+IINRQPGANIIDTVD + Sbjct: 241 YKPLIIAYRNGAPVRLSDVAEVTDSVQDIRNYGSANGKPSVLLIINRQPGANIIDTVDRI 300 Query: 301 RELLPQLQASIPSAIDMKVVLDRTPTIRASLKETEFTLILSVALVIMVVFLFLRNARATL 360 +LP L+ +IP+ I++ V++DRTPTIRASL++ E TL+LS+ LVIMVV+LFLRN RATL Sbjct: 301 NAILPYLRNTIPAQINLDVMMDRTPTIRASLRDVERTLMLSIGLVIMVVYLFLRNLRATL 360 Query: 361 IPAVAVPVSLIGTFGVMYLAGFSLDNLSLMALTIAT 396 IP+VAVPVSLIGTFGVMYL G+SLDNLSLMALT+AT Sbjct: 361 IPSVAVPVSLIGTFGVMYLCGYSLDNLSLMALTVAT 396 >YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1024 Score = 523 bits (1346), Expect = e-148, Method: Compositional matrix adjust. Identities = 264/390 (67%), Positives = 324/390 (83%) Query: 7 FIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMAATVATP 66 FIQRP+ATTLLT+ I L+GI+ F LLPVSPLPQVDYP I +SASMPGA PETMA++VATP Sbjct: 7 FIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLSRDIDGAARDVQAALNAARNLLPTGMPSN 126 LERA+G IAGV EMTSTSS STRI LQFDL+RDI+GAARDVQAALNAA++LLP+GMPS Sbjct: 67 LERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK+NP+DAPI+I+ +TSDT +QGQ+YD A + +AQK++Q GV V+VGGSS PAVR Sbjct: 127 PTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGTADVRTAVAATNANRPKGLLEDQDRNWQIYANDQAKTAAEYAPLIV 246 +ELNP+AL G+ VR A++A N RP+G ++ + +WQ+ AND+ KTA Y PLIV Sbjct: 187 VELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIV 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIDTVDNVRELLPQ 306 Y NG+PVR+QDVA V DSV DVRNAG S G+P+VL++I+R+PGANII TVD +R LP Sbjct: 247 HYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPA 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLILSVALVIMVVFLFLRNARATLIPAVAV 366 L+ASIP++I + + DR+PTIRASL E E +L+++VALVI+VVF+FLR+ RATLIPAVAV Sbjct: 307 LRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAV 366 Query: 367 PVSLIGTFGVMYLAGFSLDNLSLMALTIAT 396 PVSLIGTF MYL GFSL+NLSLMALTIAT Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396 >ECs2884 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1025 Score = 510 bits (1314), Expect = e-144, Method: Compositional matrix adjust. Identities = 257/390 (65%), Positives = 317/390 (81%) Query: 7 FIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMAATVATP 66 FI RP+AT LL++ I L GI+ FR+LPV+PLPQVD+P I +SAS+PGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLSRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD RDI+GAARDVQAA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGTADVRTAVAATNANRPKGLLEDQDRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTA++ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIDTVDNVRELLPQ 306 Y NG VR+ DVA V DSV DVRNAG +N KP++L++I + P ANII TVD++R LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLILSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TLI+SVALVI+VVFLFLR+ RAT+IPAVAV Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAV 366 Query: 367 PVSLIGTFGVMYLAGFSLDNLSLMALTIAT 396 PVSLIGTF MYL GFSL+NLSLMALTIAT Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396 >yegO [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1025 Score = 509 bits (1310), Expect = e-144, Method: Compositional matrix adjust. Identities = 257/390 (65%), Positives = 317/390 (81%) Query: 7 FIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMAATVATP 66 FI RP+AT LL++ I L GI+ FR+LPV+PLPQVD+P I +SAS+PGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIIVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLSRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD RDI+GAARDVQAA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGTADVRTAVAATNANRPKGLLEDQDRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTAV+ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAVSNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIDTVDNVRELLPQ 306 Y NG VR+ DVA V DSV DVRNAG +N KP++L++I + P ANII TVD++R LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLILSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TLI+SVALVI+VVFLFLR+ RAT+IPAV+V Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVSV 366 Query: 367 PVSLIGTFGVMYLAGFSLDNLSLMALTIAT 396 PVSLIGTF MYL GFSL+NLSLMALTIAT Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396 >ZyegO [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1025 Score = 504 bits (1299), Expect = e-142, Method: Compositional matrix adjust. Identities = 255/390 (65%), Positives = 315/390 (80%) Query: 7 FIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMAATVATP 66 FI RP+AT LL++ I L GI+ FR+LPV+PLPQVD+P I +SAS+PGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLSRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD RDI+ AARDV AA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFXRDINXAARDVXAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGTADVRTAVAATNANRPKGLLEDQDRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTA++ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIDTVDNVRELLPQ 306 Y NG VR+ DVA V DSV DVRNAG +N KP++L++I + P ANII TVD++R LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLILSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TLI+SVALVI+VVFLFLR+ RAT+IPAVAV Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAV 366 Query: 367 PVSLIGTFGVMYLAGFSLDNLSLMALTIAT 396 PVSLIGTF MYL GFSL+NLSLMALTIAT Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396