BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0016.p (300 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 195 9e-50 ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 195 9e-50 ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 195 9e-50 STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 194 1e-49 VC0896 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 180 4e-45 >gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 305 Score = 195 bits (496), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 114/287 (39%), Positives = 163/287 (56%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+R F AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + L A R++ + + +++ PSFA+ WL+P LS F YPGI + Sbjct: 67 QSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + K D+A+ G NWP L+V++ + L+ V SP LL PL+ Sbjct: 127 IQAVDRQEDKLADDVDVAIFYGRGNWP-GLRVEKLYAEYLLPVCSPLLLTGEKPLKTPED 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA+HT+L SRR DW+ + + GL Q F H VLQA + G GVAL+ +A Sbjct: 186 LAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 305 Score = 195 bits (496), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 114/287 (39%), Positives = 163/287 (56%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+R F AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + L A R++ + + +++ PSFA+ WL+P LS F YPGI + Sbjct: 67 QSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + K D+A+ G NWP L+V++ + L+ V SP LL PL+ Sbjct: 127 IQAVDRQEDKLADDVDVAIFYGRGNWP-GLRVEKLYAEYLLPVCSPLLLTGEKPLKTPED 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA+HT+L SRR DW+ + + GL Q F H VLQA + G GVAL+ +A Sbjct: 186 LAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 305 Score = 195 bits (496), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 114/287 (39%), Positives = 163/287 (56%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+R F AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + L A R++ + + +++ PSFA+ WL+P LS F YPGI + Sbjct: 67 QSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + K D+A+ G NWP L+V++ + L+ V SP LL PL+ Sbjct: 127 IQAVDRQEDKLADDVDVAIFYGRGNWP-GLRVEKLYAEYLLPVCSPLLLTGEKPLKTPED 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA+HT+L SRR DW+ + + GL Q F H VLQA + G GVAL+ +A Sbjct: 186 LAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVALANNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 305 Score = 194 bits (494), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 113/287 (39%), Positives = 164/287 (57%), Gaps = 11/287 (3%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLNA+R F AAARH SFT AA EL VT A+S QIK+LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + L A R++ + + +++ PSFA++WL+P LS F YPGI + Sbjct: 67 QSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLPPSFAIQWLVPRLSSFNSAYPGIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + K D+A+ G NWP L+V++ + L+ V SP LL PL+ Sbjct: 127 IQAVDRQEDKLADDVDVAIFYGRGNWP-GLRVEKLYAEYLLPVCSPLLLTGEKPLKTPED 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA+HT+L SRR DW+ + + GL Q F H VLQA + G G+AL+ +A Sbjct: 186 LAKHTLLHDASRR-DWQAYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGIALANNVMA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL-----FARWL 287 +++ +GRLVCPF D+ ++ +YL + S+A+L F +W+ Sbjct: 245 QSEIEAGRLVCPFNDVLVSKNAFYLVCH---DSQAELGKIAAFRQWI 288 >VC0896 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 306 Score = 180 bits (456), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 104/284 (36%), Positives = 158/284 (55%), Gaps = 5/284 (1%) Query: 7 PLNAIRAFLAAARHQSFTLAAHELNVTHGAISRQIKNLEGYLGMPLFERRTRQVLLTERG 66 PLN+++ F AAARH SFT AA EL VT A+S QIK LE +LG+ LF RR R +LLTE G Sbjct: 7 PLNSLKVFEAAARHLSFTRAAEELFVTQAAVSHQIKALEEFLGLKLFRRRNRSLLLTEEG 66 Query: 67 RQFFEEASPALEILANAARRVMRDAPTRTVVINVRPSFAVRWLIPHLSDFVERYPGIAPQ 126 + +F + LA A +++ + + I++ PSFA++WL+P L+DF ++ P I + Sbjct: 67 QSYFLDIKDIFSSLAEATDKLLERSEKGALTISLPPSFAIQWLVPRLADFNQQEPDIDVR 126 Query: 127 VVTSTATVGKAGSSFDIAVRRGETNWPETLKVQRFMEDELVLVASPALLQA-MPLEDVSG 185 + G D+A+ G +WP L+ + ++ L+ + SPALL P+E +S Sbjct: 127 IKAVDMDEGSLTDDVDVAIYYGRGSWP-GLRADKLYQEFLIPLCSPALLLGNKPMEKLSD 185 Query: 186 LARHTVLLSRSRRNDWEDWRKLAGLKRSRSQAMLHFDHVHFVLQAVVDGLGVALSPVSLA 245 LA HT+L SR+ DW+ + K GL F H VLQA G GVAL LA Sbjct: 186 LAYHTLLHDTSRK-DWKQFAKENGLDNVNVNHGPIFSHSTMVLQAAAHGQGVALGNNVLA 244 Query: 246 DNDLRSGRLVCPFPDLRLTLAPYYLGINAQAGSEAQL--FARWL 287 ++ +GRL+ PF ++ +T +Y+ + + ++ F W+ Sbjct: 245 QPEIDAGRLIAPFDEVLMTNNAFYVVCHEKQADMGRIATFRDWM 288