BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0128.p (314 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0239 [GER] COG0697 Permeases of the drug/metabolite transporte... 186 6e-47 mlr5160 [GER] COG0697 Permeases of the drug/metabolite transport... 139 8e-33 RSp0133 [GER] COG0697 Permeases of the drug/metabolite transport... 133 6e-31 AGl1685 [GER] COG0697 Permeases of the drug/metabolite transport... 120 3e-27 mlr7703 [GER] COG0697 Permeases of the drug/metabolite transport... 108 2e-23 >PA0239 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 292 Score = 186 bits (472), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 111/294 (37%), Positives = 170/294 (57%), Gaps = 7/294 (2%) Query: 3 SAVLSQLPIARTHKLGILFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRYTINLFFMA 62 +A S LP + GIL + + ++ + D K L+ Y +VM+ W RY ++ M Sbjct: 2 NASTSPLPASDQTLRGILLICAAVFLFASHDGLSKFLS-GFYPIVMVVWARYLVHTLLMV 60 Query: 63 ATLAPLYRRRHGRSILQSNRLGLQLGRGALLLGSTLIFFSVLKIVPLAEGTAMNFCAPLI 122 A P R+G ++++S R +QL R L+G++L F + L+ +PLAE TA+NF APL+ Sbjct: 61 AVFVP----RNGLAVIRSRRPLMQLARALCLIGTSLFFTTGLRYLPLAEATAVNFLAPLL 116 Query: 123 VLAISPWLLGERSYLSRWIAVLVGFTGMLIVIRPSGDIPPYGVALGLISALTQALLSILN 182 V A+S LL E+ L +W+AVL GF G+L ++RP G + L SAL L +L Sbjct: 117 VTALSVPLLKEKVSLGQWLAVLTGFIGVLFIVRPGGALFTPAALFPLGSALCFGLYQLLT 176 Query: 183 RKASQADNPMVTLFYGALVGSVVSTLLVPFFWTSHTPTMVELAILVSTGITSTIGHFLQN 242 R + +D+P + F + +++ +LLVPFFW TP+++ ++++ G GH L Sbjct: 177 RMLANSDSPTTSNFLAGIFNTLIMSLLVPFFW--QTPSLLHGLMMIALGGCGMGGHLLLT 234 Query: 243 SAYRHAEASVLTPFFYAQIISACGMGWLVFGQFPDRITVLGIAIICASGIGIAY 296 A+RHA + L PF Y QII A +G LVFG PD +LGI +ICASG+ +A+ Sbjct: 235 QAFRHAPPATLAPFSYGQIIFAGLLGLLVFGHVPDAWALLGILVICASGLVVAW 288 >mlr5160 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 313 Score = 139 bits (350), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 95/290 (32%), Positives = 154/290 (53%), Gaps = 11/290 (3%) Query: 14 THKLGILFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRYTINLFFMAATLAPLYRRRH 73 T + IL +++ + LDT+ K L LAG +++AW+R+ +++ + L R Sbjct: 12 TPPVAILCMLTTYVFFTFLDTSSKYLVLAGVSALIVAWVRFAVHVVLVGTLL------RG 65 Query: 74 GRSILQSNRLGL--QLGRGALLLGSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAISPWLL 131 R L+ + L + RG L GST+ L+ + LAE T++ F P+++ A++ LL Sbjct: 66 WRDPLRFRPVNLPAHVLRGVFLFGSTMCNILALRSLQLAETTSIYFFGPMVITALAGPLL 125 Query: 132 GERSYLSRWIAVLVGFTGMLIVIRPSGDIPPYGVALGLISALTQALLSILNRKASQADNP 191 GE + RW+A+L F G+LI+ RP + G L S L+ I+ R+ S + Sbjct: 126 GEWAGWRRWLAILAAFAGVLIITRPGVGVFGIGHLFALGSMLSNCFYVIMTRRMSSTETS 185 Query: 192 MVTLFYGALVGSVVSTLLVPF-FWTSHTPTMVELAILVSTGITSTIGHFLQNSAYRHAEA 250 + + AL +V+ ++PF F H IL+ G+ +GH+L AYR A Sbjct: 186 ESLILFSALAPTVLLLPMLPFSFSLPHDGW--HWFILLMLGVFGGVGHWLLVQAYRLATT 243 Query: 251 SVLTPFFYAQIISACGMGWLVFGQFPDRITVLGIAIICASGIGIAYIEHK 300 + L P+ Y+Q++ GW+VF QFPDR T++G AII ASG+ I + EH+ Sbjct: 244 TALAPYPYSQMVWMVISGWIVFKQFPDRWTLVGAAIIVASGLYIVHREHR 293 >RSp0133 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 316 Score = 133 bits (334), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 105/288 (36%), Positives = 152/288 (52%), Gaps = 10/288 (3%) Query: 18 GILFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRYTINLFFMAATLAPLYRRRHGRSI 77 GI FLI+ + ++ DT K +++ VVM W RY + ATL P GRS+ Sbjct: 29 GIAFLIAAVAFFAVFDTLTKYISIT-VPVVMALWFRYLFQMVATGATLLP----SRGRSL 83 Query: 78 LQSNRLGLQLGRGALLLGSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAISPWLLGERSYL 137 L++ R LQ+ RG LLL +L F L+ +P+ + TA+ PL+V ++ LGE+ Sbjct: 84 LRTRRPWLQVVRGLLLLLVSLFSFLSLRRMPVGDVTAIVMLTPLVVTFVAAVSLGEQVSA 143 Query: 138 SRWIAVLVGFTGMLIVIRPSGDIPPYGVALGLISALTQALLSILNRKASQADNPMVTLFY 197 +RWI + GF G L+VIRP G +G+ L L + A ++ + + D T FY Sbjct: 144 TRWIFMAGGFFGALMVIRPGGAAFDWGMLLPLGMVVANAAFQVVTSRLANVDEAGTTQFY 203 Query: 198 GALVGSVVSTLLVPFFWTSHTPTMVELAILVSTGITSTIGHFLQNSAYRHAEASVLTPFF 257 VG+++ T ++PF W + L IL+ GI S+ GH L AY A ++LTP+ Sbjct: 204 TGAVGALLLTCMLPFGWQALGGKWWWLLILI--GIVSSSGHALLIMAYTRAPVAMLTPYL 261 Query: 258 YAQIISACGMGWLVFGQFPDRITVLGIAIIC---ASGIGIAYIEHKRA 302 Y QI A GWLVF PD +V GIAII A+G +A E + A Sbjct: 262 YMQIGFAMIGGWLVFSHVPDGWSVAGIAIIAMCGAAGTWVAARERRMA 309 >AGl1685 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 294 Score = 120 bits (302), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 93/290 (32%), Positives = 147/290 (50%), Gaps = 17/290 (5%) Query: 16 KLGILFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRY---TINLFFMAATLAPLYRRR 72 K G L+ + + D K L A Y V +A +RY + + MAA R Sbjct: 5 KTGFLYALVAFTIFAAQDGISKHLGSA-YPPVFVAMLRYWAFAVFVLLMAA------RSA 57 Query: 73 HG-RSILQSNRLGLQLGRGALLLGSTLIFFSVLK--IVPLAEGTAMNFCAPLIVLAISPW 129 G R + +NR LQ+ RG LL + I FS+ +V LA ++ APLIV A+S Sbjct: 58 GGIRGAVMANRPWLQISRGVLL--AVQIVFSIFSFAVVGLAHSHSILASAPLIVAALSMP 115 Query: 130 LLGERSYLSRWIAVLVGFTGMLIVIRPSGDIPPYGVALGLISALTQALLSILNRKASQAD 189 LLGE RW A+ VGF G+L++++P GD + + ++A AL S+L R S++D Sbjct: 116 LLGEHVGWRRWCAIFVGFIGVLVILKPDGDGFDNKLIITFVAAFMLALYSVLTRLGSKSD 175 Query: 190 NPMVTLFYGALVGSVVSTLLVPFFWTSHTPTMVELAILVSTGITSTIGHFLQNSAYRHAE 249 + M + FY + G+ TL+ PF+W P + +++ IT GH+ A+ A+ Sbjct: 176 SAMTSFFYTGVAGAAALTLVGPFYWVPLAPQ--DWGWMLALCITGMSGHYCLIKAFELAD 233 Query: 250 ASVLTPFFYAQIISACGMGWLVFGQFPDRITVLGIAIICASGIGIAYIEH 299 A+ + PF Y Q++ +G ++G+ V G AI+ A+G+ + EH Sbjct: 234 AASVQPFSYYQLVLVSIIGVTIYGEVVTSNMVTGAAIVIAAGLFTIWREH 283 >mlr7703 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 347 Score = 108 bits (269), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 77/225 (34%), Positives = 115/225 (51%), Gaps = 12/225 (5%) Query: 86 QLGRGALLLGSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAISPWLLGERSYLSRWIAVLV 145 + RG + +G+ + F L +PL E +N+ PL+V+ S LGE + RW AV V Sbjct: 109 HVARGVVGVGAMGLGFFALTRLPLPEAITLNYAQPLLVVVFSSVFLGESIRVYRWSAVAV 168 Query: 146 GFTGMLIVIRPS----------GDIPPYGVALGLISALTQALLSILNRKASQADNPMVTL 195 G G+LI+ P D GV L++A A+ +L R Q + + Sbjct: 169 GLIGVLIISWPELTLLNSDEGLDDQEVLGVMAALVAAAISAVAMLLVRNLVQTEKTATIV 228 Query: 196 FYGALVGSVVSTLLVPFFWTSHTPTMVELAILVSTGITSTIGHFLQNSAYRHAEASVLTP 255 + + SV+S L +PF W S TP V+ A+LV G +G L SAYRHAEASV+ P Sbjct: 229 LWFSSTASVLSLLTLPFGWQSLTP--VQAALLVMAGFCGGLGQILMTSAYRHAEASVVAP 286 Query: 256 FFYAQIISACGMGWLVFGQFPDRITVLGIAIICASGIGIAYIEHK 300 F Y +I +G+ +FG T++G AI+ A+G+ I + E + Sbjct: 287 FEYTSMILGVVVGYFIFGDVTSLNTLIGGAIVVAAGVFIIWRERQ 331