BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0113.p (410 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 488 e-137 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 439 e-123 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 390 e-108 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 326 5e-89 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 308 1e-83 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 488 bits (1256), Expect = e-137, Method: Compositional matrix adjust. Identities = 238/357 (66%), Positives = 287/357 (80%) Query: 4 QAGAAANGARASFEDATYGKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTV 63 AGA + + FE+ATY KV+WRL+P L LCYV +YLDRVNVGFAKLQML DLKFS+TV Sbjct: 11 SAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETV 70 Query: 64 YGLGAGIFFLGYFVFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVTTPEMFYIMRF 123 YGLGAGIFF+GYF+FEVPSN+ILH+VGAR+WIARIMI+WG+IS AM +VTTP MFY+MRF Sbjct: 71 YGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRF 130 Query: 124 LLGVAEAGFFPGVILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWG 183 LLG+AEAGFFPG+ILYLTYWYPA RRG+ T FMT +ALSGVIGGP+SGW + GV+G Sbjct: 131 LLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYG 190 Query: 184 HTGWQWMFILEAIPSLILGVMVILYMKDRIRDADWLSEEEKRLLETNISHEESQKEHLSL 243 GWQWMF++E IPS+++G+ V+ Y+ +RI A WL++EEK LL NI+ EE+QKE + Sbjct: 191 LAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQKEDAPI 250 Query: 244 GAMFANGRVWLGALIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAM 303 A+ A+ RVWL +LIYF FVMGLYGVSFWLPT+IK TGV+DPL+VGLLTAIPY A AM Sbjct: 251 AAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAM 310 Query: 304 VLIGRSADARHERRWHVAIPAFIGCIGLLLSTQYGHNTTLAMASLTLASXDQFAGQP 360 VL+ RSAD ERRWH+AIPA G IGL+LS + NTTLAMA+LTL + P Sbjct: 311 VLVARSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLP 367 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 439 bits (1128), Expect = e-123, Method: Compositional matrix adjust. Identities = 202/344 (58%), Positives = 258/344 (75%) Query: 17 EDATYGKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTVYGLGAGIFFLGYF 76 E+ Y K W LLPLL LCYV +YLDRVNVGFAKLQM DL+FSDTVYGLGAG+FF+GYF Sbjct: 18 ENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYGLGAGMFFIGYF 77 Query: 77 VFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVTTPEMFYIMRFLLGVAEAGFFPGV 136 E+PSN+ILH+VGARLWIARIMITWGIIS MA+VTTP FY+MRFLLGVAEAGFFPG+ Sbjct: 78 FLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPGI 137 Query: 137 ILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWGHTGWQWMFILEAI 196 ILY++YW+P+ RRG++ LF+ + LSG+IG PLSGWIM G G+ GWQWMFILE I Sbjct: 138 ILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGI 197 Query: 197 PSLILGVMVILYMKDRIRDADWLSEEEKRLLETNISHEESQKEHLSLGAMFANGRVWLGA 256 PS+++G+++I +KDRI A WL+++EK +L+TNI +E + H L F RVWL Sbjct: 198 PSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYAHSRLRDAFLQPRVWLLT 257 Query: 257 LIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAMVLIGRSADARHER 316 LIYFC + G Y + FWLPT+I+ +GV D L++G LTAIP A AA M+++ RSAD ER Sbjct: 258 LIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRER 317 Query: 317 RWHVAIPAFIGCIGLLLSTQYGHNTTLAMASLTLASXDQFAGQP 360 RWH+A+ A +G +G++LST + N +AM LT+ + + P Sbjct: 318 RWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIP 361 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 390 bits (1002), Expect = e-108, Method: Compositional matrix adjust. Identities = 183/346 (52%), Positives = 255/346 (73%), Gaps = 4/346 (1%) Query: 17 EDATYGKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTVYGLGAGIFFLGYF 76 E+ TY KV +R++PLL +CY+ +YLDRVNVGFAKLQM ++L FS+ +YGLGAG+FF+GYF Sbjct: 33 ENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFIGYF 92 Query: 77 VFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVTTPEMFYIMRFLLGVAEAGFFPGV 136 FE+PSN++LHK+GARLWIARIMITWG++S A+V T FYI+RFLLG AEAGF+PGV Sbjct: 93 FFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAEAGFYPGV 152 Query: 137 ILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWGHTGWQWMFILEAI 196 ILYLTYW+P+ RRG + ALF G +G+ G PLSGWIM G GWQWMF+LEAI Sbjct: 153 ILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAI 212 Query: 197 PSLILGVMVILYMKDRIRDADWLSEEEKRLLETNISHEESQK--EHLSLGAMFANGRVWL 254 P+++LGV+++LY+ + ++ A WL+EEEK ++ +I + K H SL ++ N +W+ Sbjct: 213 PAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASH-SLMSLVKNPMLWV 271 Query: 255 GALIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAMVLIGRSADARH 314 LIYFCFVMG +G++ W+PT+I+A+GV+ + +GLL AIP+ A AMV+ RSAD Sbjct: 272 MMLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYR 331 Query: 315 ERRWHVAIPAFIGCIGLLLSTQYGHNTTLAMASLTLASXDQFAGQP 360 ERRWH+ +PA +G +G +++ NTT+++ L++A+ A P Sbjct: 332 ERRWHLVVPALLGAVGFVVAAS-ATNTTVSIIFLSMAAAGVLACAP 376 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 326 bits (836), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 165/357 (46%), Positives = 234/357 (65%) Query: 10 NGARASFEDATYGKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTVYGLGAG 69 N D+T+ +VTWRL+PLL +CYV ++LDR+N+GFAKLQM DL FSDTVYGLGAG Sbjct: 8 NSTTLPLSDSTHDRVTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLHFSDTVYGLGAG 67 Query: 70 IFFLGYFVFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVTTPEMFYIMRFLLGVAE 129 +FF+ Y +F +PSN++L ++G R WIA +M+ WG +S AM V T FY++RFLLGVAE Sbjct: 68 LFFIAYALFGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGFYLLRFLLGVAE 127 Query: 130 AGFFPGVILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWGHTGWQW 189 AGFFPG+++YL W+PA RRG+ITALF + ++GVIGGPLSGWI+ G GWQW Sbjct: 128 AGFFPGILVYLNRWFPARRRGQITALFAIAVPMAGVIGGPLSGWILEGFHDALGLRGWQW 187 Query: 190 MFILEAIPSLILGVMVILYMKDRIRDADWLSEEEKRLLETNISHEESQKEHLSLGAMFAN 249 MF++E +P ++LGV+V + + WLS+E+K LL ++ EE +K S +F+N Sbjct: 188 MFLIEGLPVVLLGVVVWCSLPESFERVTWLSDEQKHLLREELAGEEQRKTITSFSGIFSN 247 Query: 250 GRVWLGALIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAMVLIGRS 309 +VWL IYF ++ + ++FW+P++I G++ +G+L+A+PY A M+ IGRS Sbjct: 248 PQVWLLVAIYFAVMLAVNTIAFWMPSLIHGAGIAQDSRIGMLSAVPYLAGCAFMIFIGRS 307 Query: 310 ADARHERRWHVAIPAFIGCIGLLLSTQYGHNTTLAMASLTLASXDQFAGQPSRLRQP 366 +D ERRWH+ IP + GL L+ + L M L +A A P + P Sbjct: 308 SDRLRERRWHLGIPLLMAAAGLSLAALAPTSAWLVMGGLVIAGMGASAALPMFWQLP 364 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 308 bits (789), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 160/341 (46%), Positives = 213/341 (62%), Gaps = 2/341 (0%) Query: 17 EDATYGKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTVYGLGAGIFFLGYF 76 + Y V R+LP L CY+ +YLDR+N+GFAKLQM DL SD YGLGAGIFF GY Sbjct: 16 STSVYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDAAYGLGAGIFFFGYM 75 Query: 77 VFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVTTPEMFYIMRFLLGVAEAGFFPGV 136 +FEVPSN++L K+GAR ++RI+I WGI+S +M +VT FY +RFLLGV EAGF PG+ Sbjct: 76 LFEVPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALRFLLGVFEAGFAPGM 135 Query: 137 ILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWGHTGWQWMFILEAI 196 I YLT WYP R + A+ + L GVIGGP S WIM G G GWQWMF+ E I Sbjct: 136 IYYLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAGGLAGWQWMFLAEGI 195 Query: 197 PSLILGVMVILYMKDRIRDADWLSEEEKRLLETNISHEESQKEHLSLGAMFANGRVWLGA 256 PS++LG+ Y+ D+ DA WL++ +K ++ +I+ + S G ++++ A Sbjct: 196 PSILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIARAAPGQAS-SFGKALTEPKLYVLA 254 Query: 257 LIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAMVLIGRSADARHER 316 YFC + G+Y V FWLP+I+K+ G+SD +GL +AIP AM +GR +D R ER Sbjct: 255 AAYFCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAMIVAMYALGRRSDRRGER 314 Query: 317 RWHVAIPAFIGCIGLLLSTQYGHNTTLAMASLTLASXDQFA 357 H AI A +G GLL Y + A+ S+TLAS FA Sbjct: 315 HLHSAITAVLGA-GLLAWAAYATSFPAALISITLASAAIFA 354