BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0034.p (233 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1580 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 201 1e-51 YPO0471 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 109 7e-24 STM0040 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 99 7e-21 VC0677 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 99 1e-20 ZnhaR [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 98 2e-20 >VC1580 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 303 Score = 201 bits (511), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 105/209 (50%), Positives = 142/209 (67%), Gaps = 8/209 (3%) Query: 3 LEQLNFHHLRYFWRVAKLGHLTRAAEELHTSQSAVSAQIRQLEKHLGEDLFIREGRRLSL 62 + LNFHHL YFW VAK GHLTRAA++L+ SQSA+S+QIRQLE LG DLF+R+GR L L Sbjct: 14 MRHLNFHHLHYFWTVAKEGHLTRAAQQLNVSQSALSSQIRQLEGQLGHDLFVRQGRSLQL 73 Query: 63 SDTGQLVFTYADNIFGLSQEMLGRLE-GRSAGVTRLRVGSVATLSRNYQENWLRPMLSDP 121 ++ G LV YA++IF LS E+L +E G V +LR+GSVATLSRN+QEN+LRP+L Sbjct: 74 TEVGHLVLEYAESIFNLSGELLSIMESGELQRVQQLRIGSVATLSRNFQENFLRPVLGKS 133 Query: 122 SVALTLESGQLEGLLERLVQHQLDVVLANETVPADPDRPLHCRFLGSQAVSVVGPAHRWE 181 V L L S LE LL +L H+LD++L+N VP+D +P C+ + Q+V +VGP Sbjct: 134 DVRLILSSSTLEDLLGQLQMHKLDLILSNRPVPSDSTQPWRCKRIAQQSVCLVGPP---- 189 Query: 182 AGSLR---IPEDLEGIDMALPGPRHALRI 207 + +LR P+DL + +PG +R+ Sbjct: 190 SDTLRRYQFPQDLPKVKTLVPGASSEIRL 218 >YPO0471 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 299 Score = 109 bits (272), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 75/206 (36%), Positives = 102/206 (49%), Gaps = 4/206 (1%) Query: 1 MRLEQLNFHHLRYFWRVAKLGHLTRAAEELHTSQSAVSAQIRQLEKHLGEDLFIREGRRL 60 MR+ +NF+HL YFW+V K G + AAE L + ++ QI+ LE LG LF R GR L Sbjct: 1 MRMSHINFNHLYYFWQVCKEGSVVGAAEALFLTPQTITGQIKALEGRLGGKLFKRRGRGL 60 Query: 61 SLSDTGQLVFTYADNIFGLSQEMLGRLEGRSAGVTRLRVGSVATLSRNYQENWLR-PMLS 119 S+ GQLVF YAD +F LSQEML + R VG LS+ L ++ Sbjct: 61 VPSELGQLVFRYADKMFMLSQEMLDIVNYRKESHLLFDVGVADALSKRLVSQVLETAVVE 120 Query: 120 DPSVALTLESGQLEGLLERLVQHQLDVVLANETVPADPDRPLHCRFLGSQAVSVVGPAHR 179 + L E LLE+L QH+LD++L++ V + L LG +VS R Sbjct: 121 HEKIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQQEGLFSVKLGECSVSFYC---R 177 Query: 180 WEAGSLRIPEDLEGIDMALPGPRHAL 205 L P L+ + +PG R L Sbjct: 178 QPVPDLPFPASLQQKRLLIPGRRSML 203 >STM0040 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 299 Score = 99.0 bits (245), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 61/173 (35%), Positives = 92/173 (53%), Gaps = 1/173 (0%) Query: 1 MRLEQLNFHHLRYFWRVAKLGHLTRAAEELHTSQSAVSAQIRQLEKHLGEDLFIREGRRL 60 M + +N++HL YFW V K G + AAE L + ++ QI+ LE+ L LF R+GR L Sbjct: 1 MSMSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGL 60 Query: 61 SLSDTGQLVFTYADNIFGLSQEMLGRLEGRSAGVTRLRVGSVATLSRNYQENWLR-PMLS 119 S+ G+LVF YAD +F LSQEML + R VG LS+ + L ++ Sbjct: 61 EPSELGELVFRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADALSKRLVSSVLDAAVVV 120 Query: 120 DPSVALTLESGQLEGLLERLVQHQLDVVLANETVPADPDRPLHCRFLGSQAVS 172 D + L E LLE+L QH+LD+++++ + + L +G +VS Sbjct: 121 DEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGLFSVKIGECSVS 173 >VC0677 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 296 Score = 98.6 bits (244), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 68/204 (33%), Positives = 99/204 (48%), Gaps = 4/204 (1%) Query: 3 LEQLNFHHLRYFWRVAKLGHLTRAAEELHTSQSAVSAQIRQLEKHLGEDLFIREGRRLSL 62 + LN++HL YFW V K G +T+AA+ L + V+ QI+ LE L L R GR + Sbjct: 1 MSHLNYNHLYYFWMVCKQGSVTKAADALFLTPQTVTGQIKALEDRLDGKLTKRNGRSIEP 60 Query: 63 SDTGQLVFTYADNIFGLSQEMLGRLEGRSAGVTRLRVGSVATLS-RNYQENWLRPMLSDP 121 ++ GQLVF YAD +FGLS EML + VG LS R + L + D Sbjct: 61 TELGQLVFKYADRMFGLSYEMLDIVNYSQRSNLLFDVGVADALSKRLVSKILLTSVPGDN 120 Query: 122 SVALTLESGQLEGLLERLVQHQLDVVLANETVPADPDRPLHCRFLGSQAVSVVGPAHRWE 181 + L E LLE+L QH+LD++L++ V + L + LG +S + Sbjct: 121 RIHLRCFESTHEMLLEQLAQHKLDMILSDCPVDSSQSPGLFSKKLGESRMSFFSFG---D 177 Query: 182 AGSLRIPEDLEGIDMALPGPRHAL 205 P L+ + +PG R A+ Sbjct: 178 VDFAPFPAVLQSKKLLVPGSRTAM 201 >ZnhaR [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 301 Score = 97.8 bits (242), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 62/174 (35%), Positives = 92/174 (52%), Gaps = 3/174 (1%) Query: 1 MRLEQLNFHHLRYFWRVAKLGHLTRAAEELHTSQSAVSAQIRQLEKHLGEDLFIREGRRL 60 M + +N++HL YFW V K G + AAE L+ + ++ QIR LE+ L LF R+GR L Sbjct: 1 MSMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGL 60 Query: 61 SLSDTGQLVFTYADNIFGLSQEMLGRLEGRSAGVTRLRVGSVATLSRNYQENWLRPML-- 118 S+ G+LV+ YAD +F LSQEML + R VG LS+ + L + Sbjct: 61 EPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADVLSKRLVSSVLNAAVVE 120 Query: 119 SDPSVALTLESGQLEGLLERLVQHQLDVVLANETVPADPDRPLHCRFLGSQAVS 172 +P ES E LLE+L QH+LD+++++ + + L +G VS Sbjct: 121 GEPIHLRCFESTH-EMLLEQLSQHKLDMIISDCPIDSTQQEGLFSVRIGECGVS 173