BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0167.p (323 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2442 [IM] COG0761 Penicillin tolerance protein Rso Ralstonia ... 481 e-136 NMB1831 [IM] COG0761 Penicillin tolerance protein Nme Neisseria ... 411 e-115 NMA0624 [IM] COG0761 Penicillin tolerance protein NmA Neisseria ... 411 e-115 XF2416 [IM] COG0761 Penicillin tolerance protein Xfa Xylella fas... 403 e-112 STM0049 [IM] COG0761 Penicillin tolerance protein Sty Salmonella... 402 e-112 >RSc2442 [IM] COG0761 Penicillin tolerance protein Rso Ralstonia solanacearum Length = 324 Score = 481 bits (1238), Expect = e-136, Method: Compositional matrix adjust. Identities = 227/307 (73%), Positives = 270/307 (87%) Query: 6 AESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIE 65 A++E+LLAQPRGFCAGVDRAIEIVERAL +FGAPIYVRHEIVHNAYVV+DLR+KGAVF++ Sbjct: 15 ADAEVLLAQPRGFCAGVDRAIEIVERALQRFGAPIYVRHEIVHNAYVVSDLRSKGAVFVQ 74 Query: 66 ELADVPAGSTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIM 125 EL DVP G TVIFSAHGVS+A++ A RGL VFDATCPLVTKVH+EV+KMR +G EIIM Sbjct: 75 ELDDVPVGGTVIFSAHGVSRAVRQAAEARGLRVFDATCPLVTKVHVEVSKMRTQGFEIIM 134 Query: 126 IGHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPALLAYVSQTTLSVDDTAEIIAAL 185 IGH GHPEVEGTMGQ + GM LVE+V+DV RL V DPA LAYV+QTTLSVD+T EI+AA+ Sbjct: 135 IGHKGHPEVEGTMGQADDGMLLVESVDDVARLAVKDPARLAYVTQTTLSVDETQEIVAAI 194 Query: 186 RERFPAISEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRELAEKKGVA 245 + RFPA+ EPKK DICYAT NRQ+AVKFMAPQV+VVIVVGSPNSSNSNRLRELAEK GV Sbjct: 195 KARFPAVHEPKKQDICYATQNRQDAVKFMAPQVEVVIVVGSPNSSNSNRLRELAEKLGVP 254 Query: 246 AFMVDNAALIDPLWIQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLEGIEENVT 305 A+MVD + P W+ G++R+G+TAGASAPE L Q+++DR++ +GARSVR L+GI+EN++ Sbjct: 255 AYMVDTPEQVRPEWLAGKRRVGLTAGASAPEELAQSIVDRLRALGARSVRPLDGIQENMS 314 Query: 306 FPLPKGL 312 FPLP+GL Sbjct: 315 FPLPRGL 321 >NMB1831 [IM] COG0761 Penicillin tolerance protein Nme Neisseria meningitidis MC58 Length = 322 Score = 411 bits (1057), Expect = e-115, Method: Compositional matrix adjust. Identities = 205/307 (66%), Positives = 244/307 (79%), Gaps = 1/307 (0%) Query: 7 ESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIEE 66 E I+LA PRGFCAGVDRAI IVERAL +FGAPIYVRHE+VHN +VV++LR KGAVFIE+ Sbjct: 3 EKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVHNKFVVDNLREKGAVFIED 62 Query: 67 LADVPAGSTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIMI 126 LA+VP G+T+++SAHGVSKA++ EAAERG VFDATCPLVTKVH EVA++ + EIIMI Sbjct: 63 LAEVPPGATLVYSAHGVSKAVRQEAAERGFRVFDATCPLVTKVHKEVARLDAQDCEIIMI 122 Query: 127 GHAGHPEVEGTMGQTEAG-MHLVETVEDVQRLQVADPALLAYVSQTTLSVDDTAEIIAAL 185 GH GH EVEGTMGQ G M LVETV DV +L+V +P LAYVSQTTLSVD+T +IIAAL Sbjct: 123 GHKGHVEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPDKLAYVSQTTLSVDETKDIIAAL 182 Query: 186 RERFPAISEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRELAEKKGVA 245 RFP I P K DICYATTNRQ AVK +A Q D+VIVVGSPNSSNSNRLRE+A +G+ Sbjct: 183 NARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIVIVVGSPNSSNSNRLREVAASRGID 242 Query: 246 AFMVDNAALIDPLWIQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLEGIEENVT 305 A+MVDNA + W +G+ ++GVTAGASAPEVLV+ V+ I+ G +VR EG EE++ Sbjct: 243 AYMVDNAGYLQRAWFEGKNKVGVTAGASAPEVLVREVLATIRGWGHETVREGEGAEESIV 302 Query: 306 FPLPKGL 312 F LPK L Sbjct: 303 FVLPKEL 309 >NMA0624 [IM] COG0761 Penicillin tolerance protein NmA Neisseria meningitidis Z2491 Length = 322 Score = 411 bits (1057), Expect = e-115, Method: Compositional matrix adjust. Identities = 205/307 (66%), Positives = 244/307 (79%), Gaps = 1/307 (0%) Query: 7 ESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIEE 66 E I+LA PRGFCAGVDRAI IVERAL +FGAPIYVRHE+VHN +VV++LR KGAVFIE+ Sbjct: 3 EKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVHNKFVVDNLREKGAVFIED 62 Query: 67 LADVPAGSTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIMI 126 LA+VP G+T+++SAHGVSKA++ EAAERG VFDATCPLVTKVH EVA++ + EIIMI Sbjct: 63 LAEVPPGATLVYSAHGVSKAVRQEAAERGFRVFDATCPLVTKVHKEVARLDAQDCEIIMI 122 Query: 127 GHAGHPEVEGTMGQTEAG-MHLVETVEDVQRLQVADPALLAYVSQTTLSVDDTAEIIAAL 185 GH GH EVEGTMGQ G M LVETV DV +L+V +P LAYVSQTTLSVD+T +IIAAL Sbjct: 123 GHKGHVEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPDKLAYVSQTTLSVDETKDIIAAL 182 Query: 186 RERFPAISEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRELAEKKGVA 245 RFP I P K DICYATTNRQ AVK +A Q D+VIVVGSPNSSNSNRLRE+A +G+ Sbjct: 183 NARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIVIVVGSPNSSNSNRLREVAASRGID 242 Query: 246 AFMVDNAALIDPLWIQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLEGIEENVT 305 A+MVDNA + W +G+ ++GVTAGASAPEVLV+ V+ I+ G +VR EG EE++ Sbjct: 243 AYMVDNAGYLQRAWFEGKNKVGVTAGASAPEVLVREVLATIRGWGHETVREGEGAEESIV 302 Query: 306 FPLPKGL 312 F LPK L Sbjct: 303 FVLPKEL 309 >XF2416 [IM] COG0761 Penicillin tolerance protein Xfa Xylella fastidiosa 9a5c Length = 316 Score = 403 bits (1035), Expect = e-112, Method: Compositional matrix adjust. Identities = 192/309 (62%), Positives = 244/309 (78%), Gaps = 5/309 (1%) Query: 9 EILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIEELA 68 ++LLA PRGFCAGVDRAIEIV+R + G PIYVRHE+VHN +VV+DL+ +GA+F+EEL Sbjct: 2 KVLLANPRGFCAGVDRAIEIVKRTIDMLGTPIYVRHEVVHNRFVVDDLKQRGAIFVEELH 61 Query: 69 DVPAGSTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIMIGH 128 VP G+TVIFSAHGVS+A++ +AA+RGL VFDATCPLVTKVH++VA+ R GR++I+IGH Sbjct: 62 QVPDGATVIFSAHGVSQAVRRQAAQRGLKVFDATCPLVTKVHLDVARHCRTGRDMILIGH 121 Query: 129 AGHPEVEGTMGQTE-----AGMHLVETVEDVQRLQVADPALLAYVSQTTLSVDDTAEIIA 183 AGHPEVEGTMGQ + ++LVE ++DV L VA P LAY +QTTLSVDDT II Sbjct: 122 AGHPEVEGTMGQWDQERGTGRIYLVENIDDVATLHVAQPHHLAYTTQTTLSVDDTRNIID 181 Query: 184 ALRERFPAISEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRELAEKKG 243 ALR+RFP I PK DICYAT NRQ+AV+ +A + D+V+VVGSPNSSNSNRL ELA+++G Sbjct: 182 ALRQRFPTIQGPKNNDICYATQNRQDAVRELARECDLVLVVGSPNSSNSNRLSELAQREG 241 Query: 244 VAAFMVDNAALIDPLWIQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLEGIEEN 303 VA++++D+AA IDP W+ + IGVTAGASAP+VLV V+ R+ E+GA SV G E+ Sbjct: 242 VASYLIDSAAEIDPAWVIDKHHIGVTAGASAPQVLVDGVLARLYELGATSVSEHSGKPES 301 Query: 304 VTFPLPKGL 312 + F LPK L Sbjct: 302 MVFALPKAL 310 >STM0049 [IM] COG0761 Penicillin tolerance protein Sty Salmonella typhimurium LT2 Length = 316 Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust. Identities = 196/307 (63%), Positives = 242/307 (78%), Gaps = 3/307 (0%) Query: 9 EILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIEELA 68 +ILLA PRGFCAGVDRAI IVE ALA +GAPIYVRHE+VHN YVV+ LR +GA+FIE+++ Sbjct: 2 QILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRKRGAIFIEQIS 61 Query: 69 DVPAGSTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIMIGH 128 +VP G+ +IFSAHGVS+A++ EA R LTVFDATCPLVTKVHMEVA+ R G E I+IGH Sbjct: 62 EVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGH 121 Query: 129 AGHPEVEGTMGQT---EAGMHLVETVEDVQRLQVADPALLAYVSQTTLSVDDTAEIIAAL 185 AGHPEVEGTMGQ E GM+LVE+ EDV L V + L++++QTTLSVDDT+++I AL Sbjct: 122 AGHPEVEGTMGQYSNPEGGMYLVESPEDVWTLNVKNEGKLSFMTQTTLSVDDTSDVIDAL 181 Query: 186 RERFPAISEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRELAEKKGVA 245 R+RFP I P+K DICYATTNRQEAV+ +A Q DVV+VVGS NSSNSNRL ELA++ G Sbjct: 182 RKRFPKIVGPRKDDICYATTNRQEAVRALAEQADVVLVVGSKNSSNSNRLAELAQRMGRT 241 Query: 246 AFMVDNAALIDPLWIQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLEGIEENVT 305 AF++D+AA I W++ +GVTAGASAP++LVQ VI R++E G LEG EEN+ Sbjct: 242 AFLIDDAADIQEAWVKEAACVGVTAGASAPDILVQNVIARLREFGGGEAVTLEGREENIV 301 Query: 306 FPLPKGL 312 F +PK L Sbjct: 302 FEVPKEL 308