BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0135.p (391 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2214 [GEPR] COG0477 Permeases of the major facilitator superfa... 289 9e-78 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 285 2e-76 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 275 2e-73 Cj0484 [GEPR] COG0477 Permeases of the major facilitator superfa... 266 5e-71 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 266 9e-71 >PA2214 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 440 Score = 289 bits (739), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 154/361 (42%), Positives = 214/361 (59%), Gaps = 11/361 (3%) Query: 14 LTSAVSKIKWRILPLFVAMFIINYIDRVNIGFVRSHLSTDLGIGAAAFGLGAGLFFVGYA 73 L+SA++ + R+LP V M+++ +IDR N+G+ R+ L D G+G AAF GA +FF+GYA Sbjct: 11 LSSAIATSRLRLLPFLVLMYVLAFIDRANVGYARAFLQADTGLGDAAFAFGASIFFIGYA 70 Query: 74 LFEVPSNMLLQRYGARAWLTRIMFTWGLVAACMAFVQSETSFYFMRFLLGVAEAGFFPGV 133 FEVPSN++L R GAR WL RIM TWGLV+A M F +FY +RFLLGVAEAGFFPG+ Sbjct: 71 CFEVPSNLMLHRLGARVWLCRIMVTWGLVSAAMMFADDAMTFYVLRFLLGVAEAGFFPGI 130 Query: 134 VYYFTQWLPNHERGRAMAVFLSGSAIASILSGPITGALLLIEG-GGLHGWQWMFIIEGGA 192 + Y T W P R +A+ +F G +A +L GP++G LL G GL WQW+F+ EG Sbjct: 131 ILYLTYWFPQRSRAQALGLFYFGLPLALVLGGPLSGWLLEFHGIFGLANWQWLFVTEGLL 190 Query: 193 SMVFCVVVWLVLDSTPREAKWLSQEQREALAAVIAAEQAQRAANRPAHVSALSLLRDPQI 252 + + + + L PR+A WLS EQ+ AL +A E ++ A P LS LR Q+ Sbjct: 191 ASLVGIAAYFYLVDRPRDAGWLSDEQKRALEGELAEEDTRKQARGPHGF--LSALRSGQV 248 Query: 253 VLFCFIYFAIQLTIYGATFWLPTIIKKMGHFNDFQ----VGLFNSIPWIVAIAAMYLFAV 308 + FC +YF IQ+++YG F+LPT ++ F D Q VGL +IPW+ A+ L Sbjct: 249 LKFCLVYFTIQMSVYGVVFYLPT---RIASFLDGQVGLNVGLITAIPWVCALVVTRLVTR 305 Query: 309 LAARY-KKPQFWVATTLVISAAGMAISAVAGPVIGFVAVCFAGIGFKAASSLFWPIPQAY 367 A R + Q VA + +A A + + +A CFA GF + LFW +P Y Sbjct: 306 QADRSGQHRQLAVAMLGMAAAGIAASALAGNLGLAVIAFCFAASGFVSVQPLFWTLPTGY 365 Query: 368 L 368 L Sbjct: 366 L 366 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 285 bits (728), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 142/348 (40%), Positives = 221/348 (63%), Gaps = 7/348 (2%) Query: 20 KIKWRILPLFVAMFIINYIDRVNIGFVRSHLSTDLGIGAAAFGLGAGLFFVGYALFEVPS 79 K+ +RI+PL + +II Y+DRVN+GF + +S +LG A +GLGAGLFF+GY FE+PS Sbjct: 39 KVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFIGYFFFEIPS 98 Query: 80 NMLLQRYGARAWLTRIMFTWGLVAACMAFVQSETSFYFMRFLLGVAEAGFFPGVVYYFTQ 139 N+LL + GAR W+ RIM TWGL++A AFVQ+E FY +RFLLG AEAGF+PGV+ Y T Sbjct: 99 NILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAEAGFYPGVILYLTY 158 Query: 140 WLPNHERGRAMAVFLSGSAIASILSGPITGALL--LIEGGGLHGWQWMFIIEGGASMVFC 197 W P+H RG A+F +GS A I P++G ++ + G GWQWMF++E ++V Sbjct: 159 WFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAIPAVVLG 218 Query: 198 VVVWLVLDSTPREAKWLSQEQREALAAVIAAEQAQRAANRPAHVSALSLLRDPQIVLFCF 257 VV+ L LD++ + AKWL++E++ ++ I A+ +AA+ S +SL+++P + + Sbjct: 219 VVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASH----SLMSLVKNPMLWVMML 274 Query: 258 IYFAIQLTIYGATFWLPTIIKKMGHFNDFQVGLFNSIPWIVAIAAMYLFAVLAARYKKPQ 317 IYF + +G T W+PT+I+ G ++ +GL +IP+I AI AM +F+ A Y++ + Sbjct: 275 IYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYRERR 334 Query: 318 FWVATTLVISAAGMAISAVA-GPVIGFVAVCFAGIGFKAASSLFWPIP 364 + + ++ A G ++A A + + + A G A + LFW +P Sbjct: 335 WHLVVPALLGAVGFVVAASATNTTVSIIFLSMAAAGVLACAPLFWSLP 382 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 275 bits (702), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 145/350 (41%), Positives = 214/350 (61%), Gaps = 9/350 (2%) Query: 20 KIKWRILPLFVAMFIINYIDRVNIGFVRSHLSTDLGIGAAAFGLGAGLFFVGYALFEVPS 79 K+ WR++P + +++ Y+DRVN+GF + + DL +GLGAG+FF+GY LFEVPS Sbjct: 30 KVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFIGYFLFEVPS 89 Query: 80 NMLLQRYGARAWLTRIMFTWGLVAACMAFVQSETSFYFMRFLLGVAEAGFFPGVVYYFTQ 139 N++L R GAR W+ RIM +WGL++A M FV + FY MRFLLG+AEAGFFPG++ Y T Sbjct: 90 NVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGIILYLTY 149 Query: 140 WLPNHERGRAMAVFLSGSAIASILSGPITGALLLIEGG--GLHGWQWMFIIEGGASMVFC 197 W P RGR F++ A++ ++ GPI+G L GG GL GWQWMF+IEG S+V Sbjct: 150 WYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIG 209 Query: 198 VVVWLVLDSTPREAKWLSQEQREALAAVIAAEQAQRAANRPAHVSALSLLRDPQIVLFCF 257 + V LD+ A+WL+ E++ L IAAE+AQ+ A ++A ++ P++ L Sbjct: 210 LCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQK---EDAPIAA--IMASPRVWLMSL 264 Query: 258 IYFAIQLTIYGATFWLPTIIKKMGHFNDFQVGLFNSIPWIVAIAAMYLFAVLAARYKKPQ 317 IYF+ + +YG +FWLPT+IK+ G + VGL +IP+ A+ AM L A A R ++ + Sbjct: 265 IYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRERR 324 Query: 318 FWVATTLVISAAGMAISAV--AGPVIGFVAVCFAGIGFKAASSLFWPIPQ 365 + +A + A G+ +SAV + A+ +G LFW +P Sbjct: 325 WHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPT 374 >Cj0484 [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 410 Score = 266 bits (681), Expect = 5e-71, Method: Compositional matrix adjust. Identities = 140/360 (38%), Positives = 206/360 (57%), Gaps = 8/360 (2%) Query: 12 LALTSAVSKIKWRILPLFVAMFIINYIDRVNIGFVRSHLSTDLGIGAAAFGLGAGLFFVG 71 + L KI WRILPL V MF ++ +DR NI FV+SH+ D GIG AA+ LGAG+FF+G Sbjct: 7 IKLELVCKKISWRILPLIVLMFCLSMLDRTNISFVKSHIEIDAGIGEAAYALGAGIFFIG 66 Query: 72 YALFEVPSNMLLQRYGARAWLTRIMFTWGLVAACMAFVQSETSFYFMRFLLGVAEAGFFP 131 YA+FEVPSN+ L + GA+ WL+RIM TWGLV M F+Q E SFY +RFLLG+ EAGF P Sbjct: 67 YAIFEVPSNLFLHKLGAKIWLSRIMITWGLVTMAMIFIQGEISFYVLRFLLGLTEAGFSP 126 Query: 132 GVVYYFTQWLPNHERGRAMAVFLSGSAIASILSGPITGALL-LIEGGGLHGWQWMFIIEG 190 G++ Y + + P R +A ++ G IA + I+G +L WQWMF+IEG Sbjct: 127 GIILYLSYFFPAIYRSKAYGIYQMGVPIAFVFGSLISGFILDYTPNIYFKNWQWMFLIEG 186 Query: 191 GASMVFCVVVWLVLDSTPREAKWLSQEQREALAAVIAAEQAQRAANRPAHVSALSLLRDP 250 G +++ + LDS P++AKWL ++++ L + + + + S + + Sbjct: 187 GITVLVGIFCLFYLDSHPKDAKWLDIKEKDIL-----LKHIEISNTKAKDYSIKDIFKSI 241 Query: 251 QIVLFCFIYFAIQLTIYGATFWLPTIIKKMGHFN-DFQVGLFNSIPWIVAIAAMYLFAVL 309 + F F+YF IQL++YG F+LP+ I ++ N F+VGL N+IPWI A+ +F L Sbjct: 242 LVWKFVFVYFCIQLSVYGVLFYLPSKIAQILQINVGFEVGLLNAIPWIFVFIALPIFTSL 301 Query: 310 AARYKKPQFWVATTLVISAAGMAISAVAGPVIGFV-AVCFAGIGFKAASSLFWPIPQAYL 368 A + L++++ M S + F+ + A IGF +FW +P L Sbjct: 302 ADKKHSWNLHAILFLLLASLSMIASTFVTNLAAFLFFISLAAIGFIVIQPIFWNLPTQVL 361 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 266 bits (679), Expect = 9e-71, Method: Compositional matrix adjust. Identities = 141/371 (38%), Positives = 218/371 (58%), Gaps = 6/371 (1%) Query: 7 SAPAGLALTSAVSKIKWRILPLFVAMFIINYIDRVNIGFVRSHLSTDLGIGAAAFGLGAG 66 S P+ + V ++ R++PLF M++I YIDR N+ + + + + LG+ AA+GLGA Sbjct: 2 SDPSSALERATVGRVTRRLMPLFCLMYLIAYIDRQNVSYAKLDMVSALGLSEAAYGLGAS 61 Query: 67 LFFVGYALFEVPSNMLLQRYGARAWLTRIMFTWGLVAACMAFVQSETSFYFMRFLLGVAE 126 LFF+GY LFE P+N++L R GAR W RIMF+WGLV + F Q+ FY +RFLLGVAE Sbjct: 62 LFFIGYFLFEAPANLILARVGARVWFARIMFSWGLVTLALGFTQNAAMFYVLRFLLGVAE 121 Query: 127 AGFFPGVVYYFTQWLPNHERGRAMAVFLSGSAIASILSGPITGALLLIEG-GGLHGWQWM 185 AGFFPGV+Y T W P R R + +F+ SA A+ + I G LL ++G GL GWQW+ Sbjct: 122 AGFFPGVLYVLTLWYPQAHRARMVGLFMIASAFANAVGAAIGGLLLGMDGFLGLAGWQWV 181 Query: 186 FIIEGGASMVFCVVVWLVLDSTPREAKWLSQEQREALAAVIAAEQAQRAANRPAHVSALS 245 F++ G +++ V L S P +A+WL ++ LA+ +AAE+ + H A Sbjct: 182 FLVTGAPAVLLAPYVLWRLPSGPSDARWLPDVEKSWLASTLAAERGGEVDD---HRGAWK 238 Query: 246 LLRDPQIVLFCFIYFAIQLTIYGATFWLPTIIKKMGHFNDFQVGLFNSIPWIVAIAAMYL 305 + DP++++ +Y + L+ YG ++WLPTI+K G N G N IPW++ A++ Sbjct: 239 AIFDPRVLMLAGLYIGMPLSAYGLSYWLPTIVKSFGVSNTVN-GFINVIPWLLVAVALWF 297 Query: 306 FAVLAARYKKPQFWVATTLVISAAGMAISAV-AGPVIGFVAVCFAGIGFKAASSLFWPIP 364 AAR+ + +A ++++A +++S + G + F +C A AA +FW +P Sbjct: 298 VPRHAARHGASAWHIAGPVLLAAVALSLSVILPGAALKFTMLCIAAPAIFAAQPVFWSLP 357 Query: 365 QAYLDARIAAA 375 ++L AAA Sbjct: 358 PSFLSGPRAAA 368