BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0124.p (460 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 217 5e-56 RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 213 1e-54 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 211 3e-54 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 210 7e-54 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 199 1e-50 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 217 bits (552), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 153/412 (37%), Positives = 227/412 (55%), Gaps = 11/412 (2%) Query: 12 VDIGRMLDDGVFSGFQKLVVCLAALSIVMDGFDGQLIGFAIPSLIKEWGITRNAFAPAVA 71 V + ++D S +Q LV+ L + ++DGFD IG+ P+L + W +T APA Sbjct: 10 VPVREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLTPPQLAPAFG 69 Query: 72 AGLVGMGIGSAFAGLFADRFGRRMAIIGSVFVFGVATSLIAFSPDVTTIAILRFCAGLGI 131 AGL G+ +GS G ADRFGR+ ++ SV VFGVAT A S + T+ +LRF GLG+ Sbjct: 70 AGLFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLRFLTGLGL 129 Query: 132 GGALPSSTTMTAEFSPARRRTLTVTATIVCVPLGGMLAGLFANAVLPHYGWRGLFLIGGL 191 GGA+P T++AE+SP R R L VT + G L GL A +LP YGWRG+ + GG+ Sbjct: 130 GGAMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRGVLVAGGV 189 Query: 192 LPVAFSVLLWFVIPESPRYLARHPHRWDELRRLLQRMSRPVSADTGFADAREQAIETRAG 251 P+ +L +PES ++LA+ P D LR+++ R++ D G ++ + A Sbjct: 190 TPLVLLPVLALWMPESVQFLAQRPQCADALRQIVTRIAGHDHGD-GVTFIGDRPAQEGAP 248 Query: 252 FGA--LFASGQARDTMALWVAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAGAGLTAYNFG 309 F LF+ G A+ T+ LW AFF +L Y SWLP ++ +GL+ + A G Sbjct: 249 FPGRNLFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEAARVGAMVPLG 308 Query: 310 GVFGALLCALFITRFGSRLPMLLC--CLAATASALFLRSLDVASQTTLL-VVGIGLHGLF 366 G GA+ AL + R GS ++ C A +A+ L +VA+ T ++ VVG G+ G Sbjct: 309 GTIGAIALALLMDRAGSPRALIAAYFCGAIAVAAIGLAIGNVAALTAVVFVVGFGIAG-- 366 Query: 367 VNAVQSTMYALCAYIYPTQVRATGTAAALAFGRLGAILSAFAGALVITQGGA 418 Q+ + L A +YPT+ RATG + AL GR G+I + G ++T G+ Sbjct: 367 ---AQNGINLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGS 415 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 213 bits (541), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 141/410 (34%), Positives = 211/410 (51%), Gaps = 12/410 (2%) Query: 9 NQTVDIGRMLDDGVFSGFQKLVVCLAALSIVMDGFDGQLIGFAIPSLIKEWGITRNAFAP 68 + +D+ LD FS FQ VV L + +DGFD +GF P+L ++W I Sbjct: 5 SPVIDVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGT 64 Query: 69 AVAAGLVGMGIGSAFAGLFADRFGRRMAIIGSVFVFGVATSLIAFSPDVTTIAILRFCAG 128 +AGL G+ +G+ G ADR GR+ ++ +V FG+A+ L AF+P V + LRF G Sbjct: 65 VFSAGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTG 124 Query: 129 LGIGGALPSSTTMTAEFSPARRRTLTVTATIVCVPLGGMLAGLFANAVLPHYGWRGLFLI 188 LG+GGA+P++ +T+E+ P RRR T LG G+ A ++P +GWR + L Sbjct: 125 LGLGGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLF 184 Query: 189 GGLLPVAFSVLLWFVIPESPRYLARHPHRWDELRRLLQRMSR-PVSADTGFADAREQAIE 247 GG++P+ ++ F +PES RYL + + RLL R++ V+ DT F E A + Sbjct: 185 GGVIPLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPDTRFV-LHETAAK 243 Query: 248 TRAG--FGALFASGQARDTMALWVAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAGAGLTA 305 G LF T+ LW FFM+LL VY +WLPT++ G++ ++A Sbjct: 244 GAPGSPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVM 303 Query: 306 YNFGGVFGALLCALFITRFGSRLP--MLLCCLAATASALFLRSLDVASQTTLLVVGIGLH 363 Y GG GAL+ I R R P ++LCC + + L SQ T+L + + Sbjct: 304 YQLGGTVGALV----IGRMMDRYPATVVLCCTYGLGAGFLV--LTGVSQGTMLAIAVTGV 357 Query: 364 GLFVNAVQSTMYALCAYIYPTQVRATGTAAALAFGRLGAILSAFAGALVI 413 G ++ Q A A YPT R TG + AL GRLG++ A G +++ Sbjct: 358 GFCISGSQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLL 407 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 211 bits (536), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 141/407 (34%), Positives = 215/407 (52%), Gaps = 7/407 (1%) Query: 9 NQTVDIGRMLDDGVFSGFQKLVVCLAALSIVMDGFDGQLIGFAIPSLIKEWGITRNAFAP 68 Q D+ ++D Q V+ L +++DGFD IGF P + W +T AP Sbjct: 2 TQRRDLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAP 61 Query: 69 AVAAGLVGMGIGSAFAGLFADRFGRRMAIIGSVFVFGVATSLIAFSPDVTTIAILRFCAG 128 AGL+G+ G+ G +DRFGR+ I VF+FG + AFSPD+ T+ LRF G Sbjct: 62 LFGAGLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTG 121 Query: 129 LGIGGALPSSTTMTAEFSPARRRTLTVTATIVCVPLGGMLAGLFANAVLPHYGWRGLFLI 188 LG+GGA+P++ TMT+E+ PARRR VT LG G+ + ++P GW G+ ++ Sbjct: 122 LGLGGAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVL 181 Query: 189 GGLLPVAFSVLLWFVIPESPRYLARHPHRWDELRRLLQRMSRPVSADTGFADAREQAIET 248 GG+LP+ V L V+PESPR+ R + + + ++R DT F E A T Sbjct: 182 GGVLPLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFY-LIESASVT 240 Query: 249 RAGFGALFASGQARDTMALWVAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAGAGLTAYNF 308 + LF Q T+ LWV FFM+LL +Y SW+PT+L G+ A A+ Sbjct: 241 KGSIRQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQI 300 Query: 309 GGVFGALLCALFITRFGSRLPMLLCCLAATASALFLRSLDVASQTTLLVVGIGLH--GLF 366 GG GAL + + +F P + L+ A+ + + + SQ L ++ + + G+ Sbjct: 301 GGTLGALALGVLMDKFN---PFRVLTLSYAIGAICIVMIGL-SQDGLWLMALAIFGTGIG 356 Query: 367 VNAVQSTMYALCAYIYPTQVRATGTAAALAFGRLGAILSAFAGALVI 413 ++ Q + AL A +YPTQ RATG + + A GR GAI+ + +G +++ Sbjct: 357 ISGSQVGLNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMM 403 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 210 bits (534), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 139/407 (34%), Positives = 214/407 (52%), Gaps = 7/407 (1%) Query: 9 NQTVDIGRMLDDGVFSGFQKLVVCLAALSIVMDGFDGQLIGFAIPSLIKEWGITRNAFAP 68 Q D+ ++D Q V+ L +++DGFD IGF P + W +T +P Sbjct: 2 TQRRDLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSP 61 Query: 69 AVAAGLVGMGIGSAFAGLFADRFGRRMAIIGSVFVFGVATSLIAFSPDVTTIAILRFCAG 128 AGL+ + G+ G +DRFGR+ I VF+FG + AFSPD+ T+ LRF G Sbjct: 62 LFGAGLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTG 121 Query: 129 LGIGGALPSSTTMTAEFSPARRRTLTVTATIVCVPLGGMLAGLFANAVLPHYGWRGLFLI 188 LG+GGA+P++ TMT+E+ PARRR VT LG G+ + ++P GW G+ ++ Sbjct: 122 LGLGGAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVL 181 Query: 189 GGLLPVAFSVLLWFVIPESPRYLARHPHRWDELRRLLQRMSRPVSADTGFADAREQAIET 248 GG+LP+ V L V+PESPR+ R + + + ++R DT F E A T Sbjct: 182 GGVLPLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFY-LIESASVT 240 Query: 249 RAGFGALFASGQARDTMALWVAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAGAGLTAYNF 308 + LF Q T+ LWV FFM+LL +Y SW+PT+L G+ A A+ Sbjct: 241 KGSIRQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQI 300 Query: 309 GGVFGALLCALFITRFGSRLPMLLCCLAATASALFLRSLDVASQTTLLVVGIGLH--GLF 366 GG GAL + + +F P + L+ A+ + + + SQ L ++ + + G+ Sbjct: 301 GGTLGALALGVLMDKFN---PFRVLTLSYAIGAICIVMIGL-SQDGLWLMALAIFGTGIG 356 Query: 367 VNAVQSTMYALCAYIYPTQVRATGTAAALAFGRLGAILSAFAGALVI 413 ++ Q + AL A +YPTQ RATG + + A GR GAI+ + +G +++ Sbjct: 357 ISGSQVGLNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMM 403 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 199 bits (506), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 142/409 (34%), Positives = 227/409 (55%), Gaps = 5/409 (1%) Query: 10 QTVDIGRMLDDGVFSGFQKLVVCLAALSIVMDGFDGQLIGFAIPSLIKEWGITRNAFAPA 69 + +D+ ++ S +Q +V L L + +DG D +GF P+L ++WGI R + P Sbjct: 10 ERLDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGIDRASLGPV 69 Query: 70 VAAGLVGMGIGSAFAGLFADRFGRRMAIIGSVFVFGVATSLIAFSPDVTTIAILRFCAGL 129 ++A L+GM G+ +G ADR+GR++ ++ +VF+FG+ + A+S +V + LRF GL Sbjct: 70 MSAALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLLALRFLTGL 129 Query: 130 GIGGALPSSTTMTAEFSPARRRTLTVTATIVCVPLGGMLAGLFANAVLPHYGWRGLFLIG 189 G+G A+P++TT+ +E++P R ++L VT+ LG G + ++P +GW L L+G Sbjct: 130 GLGAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFGWHSLLLLG 189 Query: 190 GLLPVAFSVLLWFVIPESPRYLARHPHRWDELRRLLQRMS-RPVSADTGFADAREQAIET 248 GLLP+ +V+L F +PES RYL + +R++L ++ V+ F +Q ++ Sbjct: 190 GLLPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFHVPEQQTVQA 249 Query: 249 RAGFGALFASGQARDTMALWVAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAGAGLTAYNF 308 R F +F+ + T+ LW+ +FM L+ VY SWLPT++ G S A + F Sbjct: 250 RNVFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAAFIGALFQF 309 Query: 309 GGVFGALLCALFITRFG-SRLPMLLCCLAATASALFLRSLDVASQTTLLVVGIGLHGLFV 367 GGV A+ + RF ++ L LA + +SL Q TLL + L G+ + Sbjct: 310 GGVLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSL---GQVTLLATLVLLAGMCI 366 Query: 368 NAVQSTMYALCAYIYPTQVRATGTAAALAFGRLGAILSAFAGALVITQG 416 N QS M +L A YPTQ RATG + L GR GAIL A+ GA ++ G Sbjct: 367 NGAQSAMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLG 415