BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0084.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 303 8e-82 RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 285 1e-76 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 279 1e-74 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 258 2e-68 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 258 3e-68 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 303 bits (775), Expect = 8e-82, Method: Compositional matrix adjust. Identities = 178/429 (41%), Positives = 251/429 (58%), Gaps = 6/429 (1%) Query: 10 PTVHVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPV 69 P + V +++ RF AFQ+ ++LLC + IDGFD +G++APA+ DW + A LG V Sbjct: 6 PVIDVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGTV 65 Query: 70 FGAGLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGF 129 F AGL G+++G+L+ P+ DR GR+ L+ + F L + + ++ L+ LRF+TG Sbjct: 66 FSAGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTGL 125 Query: 130 GLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVG 189 GLG MPNA+AL E+ P R ++ CGFT+G+ GG V+A L+P +GW +V G Sbjct: 126 GLGGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLFG 185 Query: 190 GAVPLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVVKETKAEG 249 G +PL+L M+ LPES+++LV V R L ++ P V D T V+ ET A+G Sbjct: 186 GVIPLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPD-TRFVLHETAAKG 244 Query: 250 M---PVAALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSL 306 PV LF T+LLW + FM+L+ +Y ++NWLPTLI G + ++A I Sbjct: 245 APGSPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVMY 304 Query: 307 QVGGVIGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIV 366 Q+GG +G L +GR + R+ T VL + L + L G + +L +AV GFCI Sbjct: 305 QLGGTVGALVIGRMMDRYPATVVLCCTYGLGAGFLVLTG--VSQGTMLAIAVTGVGFCIS 362 Query: 367 GGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAV 426 G Q NA A FYPT R TGI WALGIGR+GSV G +IGG L+A LFL AV Sbjct: 363 GSQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLLVAV 422 Query: 427 PALISALTI 435 PA I++L I Sbjct: 423 PAAIASLAI 431 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 285 bits (730), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 175/428 (40%), Positives = 244/428 (57%), Gaps = 12/428 (2%) Query: 8 ALP---TVHVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKA 64 ALP V V +V++ R A+Q +L LC ++DGFD A+GY+APA+ W ++ Sbjct: 3 ALPARADVPVREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLTPP 62 Query: 65 SLGPVFGAGLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLR 124 L P FGAGLFG++LGS+ L PV DR+GR+PVL++S L F + LA +L+ L++LR Sbjct: 63 QLAPAFGAGLFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLR 122 Query: 125 FITGFGLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHA 184 F+TG GLG MP + L E+SP R+ + L GFT G A GG V+A ++P YGW Sbjct: 123 FLTGLGLGGAMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRG 182 Query: 185 VFWVGGAVPLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVV-- 242 V GG PLVL + +W+PES+QFL +RP Q A LR++ I D + V Sbjct: 183 VLVAGGVTPLVLLPVLALWMPESVQFLA--QRP--QCADALRQIVTRIAGHDHGDGVTFI 238 Query: 243 -KETKAEGMPVAA--LFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMA 299 EG P LF DG A TVLLW F +L Y L++WLP ++RD G + + A Sbjct: 239 GDRPAQEGAPFPGRNLFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEA 298 Query: 300 VLIGTSLQVGGVIGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVI 359 +G + +GG IG ++L + R G R L + + +++A IG A L V Sbjct: 299 ARVGAMVPLGGTIGAIALALLMDRAGSPRALIAAYFCGAIAVAAIGLAIGNVAALTAVVF 358 Query: 360 VAGFCIVGGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNAS 419 V GF I G Q +N LA YPT R+TG+ WALG+GR GS+ G ++GG L+ + + Sbjct: 359 VVGFGIAGAQNGINLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGSVQT 418 Query: 420 LFLAAAVP 427 LF A+P Sbjct: 419 LFGIIALP 426 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 279 bits (713), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 171/416 (41%), Positives = 250/416 (60%), Gaps = 4/416 (0%) Query: 5 TSGALPTVH---VDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGV 61 S +LP V V + +Q+ ++LLC L + +DG D AMG++APA+ DWG+ Sbjct: 2 NSPSLPAVERLDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGI 61 Query: 62 SKASLGPVFGAGLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLL 121 +ASLGPV A L GM+ G+L P+ DRYGR+ VL+ + F L LA+ T ++QLL Sbjct: 62 DRASLGPVMSAALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLL 121 Query: 122 VLRFITGFGLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYG 181 LRF+TG GLG+ MPNA L+ E++P + + + CGF +G A GGFVSA LIP +G Sbjct: 122 ALRFLTGLGLGAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFG 181 Query: 182 WHAVFWVGGAVPLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVV 241 WH++ +GG +PLVL + +L LPES ++LV+ R +V + L + P V ++ V Sbjct: 182 WHSLLLLGGLLPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFHV 241 Query: 242 VKETKAEGMPV-AALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAV 300 ++ + V A +F + T+LLWL FM L+ +Y L++WLPTL+RD+G S A Sbjct: 242 PEQQTVQARNVFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAA 301 Query: 301 LIGTSLQVGGVIGTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIV 360 IG Q GGV+ +++G + RF +V+G +LLA + +G+ LL V++ Sbjct: 302 FIGALFQFGGVLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSLGQVTLLATLVLL 361 Query: 361 AGFCIVGGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWT 416 AG CI G Q A+ +LA FYPT R+TG+ W LGIGR G+++G IG L+ L W Sbjct: 362 AGMCINGAQSAMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLGWN 417 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 258 bits (659), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 151/426 (35%), Positives = 248/426 (58%), Gaps = 1/426 (0%) Query: 13 HVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGA 72 + +++ G Q+ +++ C L +++DGFD A+G++AP I W ++ L P+FGA Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGA 65 Query: 73 GLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGFGLG 132 GL G+ G+L+ P+ DR+GR+ V+ L F LA+ L L+ LRF+TG GLG Sbjct: 66 GLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 133 SIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVGGAV 192 MPN + + E+ P+ R + L+ CGFT+G+A GG VSA L+P GWH + +GG + Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 193 PLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVVKETKAEGMPV 252 PL+L +A+LV LPES ++ V + P+ +A+ + + +D ++ + +G + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKG-SI 244 Query: 253 AALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSLQVGGVI 312 LF + +T++LW++ FM+L+ +Y LS+W+PTL+ G A + + Q+GG + Sbjct: 245 RQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTL 304 Query: 313 GTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIVGGQPAV 372 G L+LG + +F RVL + + + I +IG L+ +A+ G I G Q + Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 373 NALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAVPALISA 432 NAL T YPT R+TG+ W+ IGR G++VG + GG ++A+ ++ +LF AVPA ISA Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 433 LTIARL 438 + + L Sbjct: 425 VMLTLL 430 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 258 bits (658), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 150/426 (35%), Positives = 247/426 (57%), Gaps = 1/426 (0%) Query: 13 HVDQVVEQGRFGAFQFGLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGA 72 + +++ G Q+ +++ C L +++DGFD A+G++AP I W ++ L P+FGA Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFGA 65 Query: 73 GLFGMLLGSLVLTPVGDRYGRRPVLILSTLFFALCMLATPMVTTLDQLLVLRFITGFGLG 132 GL + G+L+ P+ DR+GR+ V+ L F LA+ L L+ LRF+TG GLG Sbjct: 66 GLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 133 SIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPAYGWHAVFWVGGAV 192 MPN + + E+ P+ R + L+ CGFT+G+A GG VSA L+P GWH + +GG + Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 193 PLVLGLAMLVWLPESIQFLVLHRRPRTQVARWLRKLDPNIVIDDKTEVVVKETKAEGMPV 252 PL+L +A+LV LPES ++ V + P+ +A+ + + +D ++ + +G + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKG-SI 244 Query: 253 AALFRDGRAGVTVLLWLISFMNLINLYFLSNWLPTLIRDAGYSTSMAVLIGTSLQVGGVI 312 LF + +T++LW++ FM+L+ +Y LS+W+PTL+ G A + + Q+GG + Sbjct: 245 RQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTL 304 Query: 313 GTLSLGRFIQRFGFTRVLGSCFLLACLSIALIGKLATVPALLFVAVIVAGFCIVGGQPAV 372 G L+LG + +F RVL + + + I +IG L+ +A+ G I G Q + Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 373 NALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWTNASLFLAAAVPALISA 432 NAL T YPT R+TG+ W+ IGR G++VG + GG ++A+ ++ +LF AVPA ISA Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 433 LTIARL 438 + + L Sbjct: 425 VMLTLL 430