BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0005.p (495 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2540_2 [QR] COG0500 SAM-dependent methyltransferases Pae Pseud... 415 e-115 YPO2814_2 [QR] COG0500 SAM-dependent methyltransferases Ype Yers... 354 2e-97 Z2317_2 [QR] COG0500 SAM-dependent methyltransferases EcZ Escher... 350 3e-96 ynbC_2 [QR] COG0500 SAM-dependent methyltransferases Eco Escheri... 350 4e-96 ECs2012_2 [QR] COG0500 SAM-dependent methyltransferases Ecs Esch... 346 6e-95 >PA2540_2 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudomonas aeruginosa Length = 312 Score = 415 bits (1066), Expect = e-115, Method: Compositional matrix adjust. Identities = 216/309 (69%), Positives = 250/309 (80%), Gaps = 1/309 (0%) Query: 185 AREFILRQFAQPWSRPDLRQAHRHGPTFDEAQALAAPLQALSPKGLYWAGYRANLKLGGL 244 AR F+L FA RP L A R G T EA+ALAAPL SP+ LYW RA L+LG L Sbjct: 1 ARRFLLEAFATAPERPSLLDADRLGHTCAEAEALAAPLPKNSPRDLYWRATRAGLRLGSL 60 Query: 245 LSAGVALGHRTGFDSGSTLDYVYRNRPEGAGPLGRAIDRQYLDAIGWKGIRQRKLHIEQL 304 S GV LG TGFDSGSTLDYVYRN+P G+GPLGR IDR YLD+IGW+GIRQRKLH+E+L Sbjct: 61 WSDGVKLGFDTGFDSGSTLDYVYRNQPCGSGPLGRLIDRNYLDSIGWRGIRQRKLHVEEL 120 Query: 305 LRLALARLQAEGQPLRVLDIAAGHGRYVLEALES-GPRPESILLRDYSELNVRQGSALIA 363 LRLA+ RL+ E + +R++DIAAGHGRY+LEAL+ P PESILLRDYSE+NVR GSALI Sbjct: 121 LRLAMQRLREEQREVRIVDIAAGHGRYILEALQGVEPLPESILLRDYSEINVRDGSALIE 180 Query: 364 EKGLGEIARFVQGDAFDRASLAAVTPRPTVGIVSGLYELFPDNDAVATSLAGMADAIAPG 423 KGL IARFV+GDAFDRA LAA+ P+P++G+VSGLYELF DN V SLAG+ +A+ G Sbjct: 181 SKGLAGIARFVKGDAFDRADLAALQPKPSLGVVSGLYELFADNRMVGDSLAGLGEALEEG 240 Query: 424 GYLIYTGQPWHPQLEMIARALTSHRGGQAWVMRRRTQAEMDQLVAEAGFEKIEQRIDQWG 483 GYL+YTGQPWHPQLE+IARALTSHR GQAWVMRRRTQAEMDQLVA AGF KI QR+DQWG Sbjct: 241 GYLVYTGQPWHPQLELIARALTSHRQGQAWVMRRRTQAEMDQLVAAAGFRKITQRVDQWG 300 Query: 484 IFTVSLARR 492 IF+VSLA++ Sbjct: 301 IFSVSLAQK 309 >YPO2814_2 [QR] COG0500 SAM-dependent methyltransferases Ype Yersinia pestis Length = 312 Score = 354 bits (909), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 176/308 (57%), Positives = 225/308 (73%) Query: 186 REFILRQFAQPWSRPDLRQAHRHGPTFDEAQALAAPLQALSPKGLYWAGYRANLKLGGLL 245 + FI R +A D R P+ D + L AP ++ S +G+++A +K G Sbjct: 2 KNFIDRLYATAPYAFDYSHEDRWSPSADAYRELQAPPKSRSLEGMFYAALSFGMKTIGRQ 61 Query: 246 SAGVALGHRTGFDSGSTLDYVYRNRPEGAGPLGRAIDRQYLDAIGWKGIRQRKLHIEQLL 305 S G+ LG+ TGFDSGSTLDYVYRN+PEG G LGR ID YL+++GW+GIR RK++I+Q++ Sbjct: 62 SKGMLLGYETGFDSGSTLDYVYRNQPEGNGILGRMIDHNYLNSVGWRGIRVRKVNIQQMI 121 Query: 306 RLALARLQAEGQPLRVLDIAAGHGRYVLEALESGPRPESILLRDYSELNVRQGSALIAEK 365 A+A++Q P+RV+DIAAGHGRYVL+ALE ESILLRDYS+LNV +G A+I E+ Sbjct: 122 EQAVAKIQLSHMPVRVVDIAAGHGRYVLDALEKQQGIESILLRDYSDLNVEKGQAMIEER 181 Query: 366 GLGEIARFVQGDAFDRASLAAVTPRPTVGIVSGLYELFPDNDAVATSLAGMADAIAPGGY 425 GL +A+F +G+AFD SLA + P PT+GIVSGLYELFPDND + TSLAG+A AI PGG Sbjct: 182 GLSHVAQFRKGNAFDYDSLATLDPAPTLGIVSGLYELFPDNDLIKTSLAGLAAAIPPGGM 241 Query: 426 LIYTGQPWHPQLEMIARALTSHRGGQAWVMRRRTQAEMDQLVAEAGFEKIEQRIDQWGIF 485 L+YTGQPWHPQL+ IA LTSH+ G W+MR R+Q EMD LV +AGFEK Q ID++GIF Sbjct: 242 LVYTGQPWHPQLKTIAYTLTSHQNGIPWMMRVRSQKEMDTLVEQAGFEKCHQVIDEFGIF 301 Query: 486 TVSLARRK 493 TVSLA RK Sbjct: 302 TVSLAVRK 309 >Z2317_2 [QR] COG0500 SAM-dependent methyltransferases EcZ Escherichia coli O157:H7 EDL933 Length = 311 Score = 350 bits (899), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 174/308 (56%), Positives = 225/308 (73%) Query: 186 REFILRQFAQPWSRPDLRQAHRHGPTFDEAQALAAPLQALSPKGLYWAGYRANLKLGGLL 245 + FI R +A + D + R GP+ D + L+ LSP L + R +KL G Sbjct: 2 QSFISRLYANKSQKFDYQHEDRTGPSADRWRLLSGGPVPLSPVDLAYRFMRKAMKLFGTH 61 Query: 246 SAGVALGHRTGFDSGSTLDYVYRNRPEGAGPLGRAIDRQYLDAIGWKGIRQRKLHIEQLL 305 SAG+ LG TGFDSGS+LDYVY+N+P+G+ GR ID+ YL+++GW+GIRQRK H++ L+ Sbjct: 62 SAGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLIDKIYLNSVGWRGIRQRKTHLQILI 121 Query: 306 RLALARLQAEGQPLRVLDIAAGHGRYVLEALESGPRPESILLRDYSELNVRQGSALIAEK 365 + A+A L A+G +RV+DIAAGHGRYVL+AL + P ILLRDYSELNV QG +IA++ Sbjct: 122 KQAVADLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQEMIAQR 181 Query: 366 GLGEIARFVQGDAFDRASLAAVTPRPTVGIVSGLYELFPDNDAVATSLAGMADAIAPGGY 425 G+ RF QGDAF+ L+A+TPRPT+ IVSGLYELFP N+ V SLAG+A+AI PGG Sbjct: 182 GMSGRVRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPGNEQVKNSLAGLANAIEPGGI 241 Query: 426 LIYTGQPWHPQLEMIARALTSHRGGQAWVMRRRTQAEMDQLVAEAGFEKIEQRIDQWGIF 485 L+YTGQPWHPQLE+IA LTSH+ G+ WVMR R+Q EMD LV +AGF+K QRID+WGIF Sbjct: 242 LLYTGQPWHPQLELIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDAGFDKCTQRIDEWGIF 301 Query: 486 TVSLARRK 493 TVS+A R+ Sbjct: 302 TVSMAVRR 309 >ynbC_2 [QR] COG0500 SAM-dependent methyltransferases Eco Escherichia coli K12 Length = 311 Score = 350 bits (899), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 173/308 (56%), Positives = 225/308 (73%) Query: 186 REFILRQFAQPWSRPDLRQAHRHGPTFDEAQALAAPLQALSPKGLYWAGYRANLKLGGLL 245 + FI R +A + D + GP+ D + L+ LSP L + R +KL G Sbjct: 2 QSFISRLYANKSQKFDYQHEDCTGPSADRWRLLSGGPVPLSPVDLAYRFMRKAMKLFGTH 61 Query: 246 SAGVALGHRTGFDSGSTLDYVYRNRPEGAGPLGRAIDRQYLDAIGWKGIRQRKLHIEQLL 305 S+G+ LG TGFDSGS+LDYVY+N+P+G+ GR +D+ YL+++GW+GIRQRK H++ L+ Sbjct: 62 SSGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLVDKIYLNSVGWRGIRQRKTHLQILI 121 Query: 306 RLALARLQAEGQPLRVLDIAAGHGRYVLEALESGPRPESILLRDYSELNVRQGSALIAEK 365 + A+A L A+G +RV+DIAAGHGRYVL+AL + P ILLRDYSELNV QG +IA++ Sbjct: 122 KQAVADLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQEMIAQR 181 Query: 366 GLGEIARFVQGDAFDRASLAAVTPRPTVGIVSGLYELFPDNDAVATSLAGMADAIAPGGY 425 G+ RF QGDAF+ L+A+TPRPT+ IVSGLYELFP+N+ V SLAG+A+AI PGG Sbjct: 182 GMSGRVRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPENEQVKNSLAGLANAIEPGGI 241 Query: 426 LIYTGQPWHPQLEMIARALTSHRGGQAWVMRRRTQAEMDQLVAEAGFEKIEQRIDQWGIF 485 LIYTGQPWHPQLEMIA LTSH+ G+ WVMR R+Q EMD LV +AGF+K QRID+WGIF Sbjct: 242 LIYTGQPWHPQLEMIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDAGFDKCTQRIDEWGIF 301 Query: 486 TVSLARRK 493 TVS+A R+ Sbjct: 302 TVSMAVRR 309 >ECs2012_2 [QR] COG0500 SAM-dependent methyltransferases Ecs Escherichia coli O157:H7 Length = 305 Score = 346 bits (888), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 172/303 (56%), Positives = 222/303 (73%) Query: 191 RQFAQPWSRPDLRQAHRHGPTFDEAQALAAPLQALSPKGLYWAGYRANLKLGGLLSAGVA 250 R +A + D + R GP+ D + L+ LSP L + R +KL G SAG+ Sbjct: 1 RLYANKSQKFDYQHEDRTGPSADRWRLLSGGPVPLSPVDLAYRFMRKAMKLFGTHSAGLH 60 Query: 251 LGHRTGFDSGSTLDYVYRNRPEGAGPLGRAIDRQYLDAIGWKGIRQRKLHIEQLLRLALA 310 LG TGFDSGS+LDYVY+N+P+G+ GR ID+ YL+++GW+GIRQRK H++ L++ A+A Sbjct: 61 LGMSTGFDSGSSLDYVYQNQPQGSNAFGRLIDKIYLNSVGWRGIRQRKTHLQILIKQAVA 120 Query: 311 RLQAEGQPLRVLDIAAGHGRYVLEALESGPRPESILLRDYSELNVRQGSALIAEKGLGEI 370 L A+G +RV+DIAAGHGRYVL+AL + P ILLRDYSELNV QG +IA++G+ Sbjct: 121 DLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQEMIAQRGMSGR 180 Query: 371 ARFVQGDAFDRASLAAVTPRPTVGIVSGLYELFPDNDAVATSLAGMADAIAPGGYLIYTG 430 RF QGDAF+ L+A+TPRPT+ IVSGLYELFP N+ V SLAG+A+AI PGG L+YTG Sbjct: 181 VRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPGNEQVKNSLAGLANAIEPGGILLYTG 240 Query: 431 QPWHPQLEMIARALTSHRGGQAWVMRRRTQAEMDQLVAEAGFEKIEQRIDQWGIFTVSLA 490 QPWHPQLE+IA LTSH+ G+ WVMR R+Q EMD LV +AGF+K QRID+WGIFTVS+A Sbjct: 241 QPWHPQLELIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDAGFDKCTQRIDEWGIFTVSMA 300 Query: 491 RRK 493 R+ Sbjct: 301 VRR 303