BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0343.p (1376 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MT2121 [H] COG1429 Cobalamin biosynthesis protein CobN and relat... 971 0.0 Rv2062c [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 971 0.0 alr1689 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 960 0.0 slr1211 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 872 0.0 RSp0626 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 851 0.0 >MT2121 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases MtC Mycobacterium tuberculosis CDC1551 Length = 1195 Score = 971 bits (2511), Expect = 0.0, Method: Compositional matrix adjust. Identities = 563/1326 (42%), Positives = 745/1326 (56%), Gaps = 203/1326 (15%) Query: 65 LAAAQVIVLRVLGRLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQ 124 LA A ++V+R+LG A Q + V A G +++SG D EL ST A Sbjct: 44 LAEASIVVIRILGGYRAWQ---SGIDTVIAGGVPAVLVSGEQAADAELTDRSTVAAGTAL 100 Query: 125 QALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAGIADWLAL 184 QA Y GG NL ++ L D +L++G+G+ P A P G+ Sbjct: 101 QAHIYLAHGGVDNLRELHAFLCDTVLMTGFGFTPPVATPTWGVLE--------------- 145 Query: 185 RAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAGGGQAL 244 R A P + +++YRA L+GNT +++AL A+E G LP++ +SLR A Sbjct: 146 RPDAGKTGPTIAVLYYRAQHLAGNTGYVEALCRAIEDAGGRPLPLYCASLRT------AE 199 Query: 245 PPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAG---------WSVSVLEQLDLPVLQA 295 P L+ G D ++ T + AGGV PA W+V L LD+P+LQ Sbjct: 200 PRLLERLGGA--DAMVVTV------LAAGGVKPAAASAGGDDDSWNVEHLAALDIPILQG 251 Query: 296 ITSGMTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETTDSGAVQYQPLPDRV 355 + + QW + G++PLD A V +PEFDGRII VP SFKE D G + Y P+R Sbjct: 252 LCLTSPRDQWCANDDGLSPLDVASQVAVPEFDGRIITVPFSFKEIDDDGLISYVADPERC 311 Query: 356 RRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSADG 415 R+AGLA R RLR A+KR+A +F+ +K ++IGNAVGLD P S +A+L+A+ G Sbjct: 312 ARVAGLAVRHARLRQVAPADKRVALVFSAYPTKHARIGNAVGLDTPASAVALLQAMRQRG 371 Query: 416 YAIDALP----QTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSL 471 Y + LP G ALIH L++ +D LTE QL R+ A Y WFA LP L Sbjct: 372 YRVGDLPGVESNDGDALIHALIECGGHDPDWLTEGQLAGNPIRVSAKEYRDWFATLPAEL 431 Query: 472 QDKMQRQWGAAPGQAYVHDQH-----LVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDL 526 D + WG PG+ +V H +VIA L GN + +QPPRG+G +P AIYH PDL Sbjct: 432 TDVVTAYWGPPPGELFVDRSHDPDGEIVIAALRAGNLVLMVQPPRGFGENPVAIYHDPDL 491 Query: 527 PPTHHYYALYRWLD----EEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPL 582 PP+HHY A YRWLD +GAHA+VH+GKHG LEWLPGK +G+S C PDA LGD+PL Sbjct: 492 PPSHHYLAAYRWLDTGFSNGFGAHAVVHLGKHGNLEWLPGKTLGMSASCGPDAALGDLPL 551 Query: 583 FYPFIINDPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSK 642 YPF++NDPGEG+QAKRRAHAV+VDHL PPM A++YG +A+L QL+DE+ V LDP K Sbjct: 552 IYPFLVNDPGEGTQAKRRAHAVLVDHLIPPMARAETYGDIARLEQLLDEHASVAALDPGK 611 Query: 643 LPLLQQQIWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHA 702 LP ++QQIW L+R +D HD G Sbjct: 612 LPAIRQQIWTLIRAAKMD-----------------------------------HDLGLTE 636 Query: 703 HHDHDHAHEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQM 762 + D + ++ +DG+LCE+ QIRDGLHILG+ P Q Sbjct: 637 RPEEDSFDD------------------MLLHVDGWLCEIKDVQIRDGLHILGQNPTGEQE 678 Query: 763 PDMLVALTRLPN-----QDLPGLQEEVARLFGLSLDMLLEHKGRRLNIDDALARCADRPI 817 D+++A+ R +PGL++ GL+ D E R +D Sbjct: 679 LDLVLAILRARQLFGGAHAIPGLRQA----LGLAEDGTDE----RATVDQ---------- 720 Query: 818 VTRADALEAIDALCLRLMQALQEHDFAPTAIDGVLGSVFAALEQASPEQRPRLQPAMSQA 877 T A A E L+ ALQ + P+A D + G+ AA Sbjct: 721 -TEAKARE--------LVAALQATGWDPSAADRLTGNADAA------------------- 752 Query: 878 ATSVLGXRLQPAMSQAATSVLPSRRAADTGAVRCVLAFACEELVPRLHRTSEEIGNLLNG 937 VL FA E++PRL T+ EI +L Sbjct: 753 ---------------------------------AVLRFAATEVIPRLAGTATEIEQVLRA 779 Query: 938 LRGGYIPAGPSGSPTRGMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLAREVLQRHHRET 997 L G +IPAGPSGSP RG+ ++LPTGRNFYSVDP++VPS+ AW G LA +L R+ E Sbjct: 780 LDGRFIPAGPSGSPLRGLVNVLPTGRNFYSVDPKAVPSRLAWEAGVALADSLLARYRDEH 839 Query: 998 GHYPESVAISIWGTSAMRTHGDDVAQILWLMGARPLWRAGNRQVAGVELVPLE--ELQRP 1055 G +P SV +S+WGTSAMRT GDD+A++L L+G RP+W +R+V ++L P++ EL RP Sbjct: 840 GRWPRSVGLSVWGTSAMRTAGDDIAEVLALLGVRPVWDDASRRV--IDLAPMQPAELGRP 897 Query: 1056 RIDVTTRISGFFRDAFPQLIELIDDAVQLAIAADEPETMNFVRKHYLHDLAQGMGAGLGQ 1115 RIDVT RISGFFRDAFP ++ ++DDAV+L DE N+VR H DLA G Sbjct: 898 RIDVTVRISGFFRDAFPHVVTMLDDAVRLVADLDEAAEDNYVRAHAQADLAHH-----GD 952 Query: 1116 AEAAAQASYRVFGAKPGSYGAGILPLIQEKNWQDQADFAEAYINWGGFAYGRKVQGADQR 1175 +A+ R+FG+KPG+YGAG+L LI ++W+D AD A+ Y WGGFAYGR + G + Sbjct: 953 QR---RATTRIFGSKPGTYGAGLLQLIDSRSWRDDADLAQVYTAWGGFAYGRDLDGREAI 1009 Query: 1176 DAFRQRLAGVQVALHNQDNHEHDIFDSDDYLQYHGGMIATIRALSGQQPRHYFGDSHDPQ 1235 D ++ + VA N D EHDI DSDDY QYHGGM+AT+RAL+GQ P Y GD+ P Sbjct: 1010 DDMNRQYRRIAVAAKNTDTREHDIADSDDYFQYHGGMVATVRALTGQAPAAYIGDNTRPD 1069 Query: 1236 RAAVRDLKEETLRVFRARVVNPKWLASIQRHGYKGGLELSATVDYLFGYDATAQVLDDWM 1295 R L EET RVFRARVVNP+W+A+++RHGYKG E++ATVDYLFGYDATA V+ DWM Sbjct: 1070 AIRTRTLSEETTRVFRARVVNPRWMAAMRRHGYKGAFEMAATVDYLFGYDATAGVMADWM 1129 Query: 1296 YQQLAETYGFDPAMRQFLEEANPWAQNAIAERLLEAASRGMWQAPDAQTLERLRQLYLHS 1355 Y+QL + Y D R F+ E+NPWA + +AERLLEAA RG+W P +TL+ LRQ+ L + Sbjct: 1130 YEQLTQRYVLDAQNRTFMTESNPWALHGMAERLLEAAGRGLWAQPAPETLDGLRQVLLET 1189 Query: 1356 ETLLEA 1361 E LEA Sbjct: 1190 EGDLEA 1195 >Rv2062c [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Mtu Mycobacterium tuberculosis H37Rv Length = 1194 Score = 971 bits (2510), Expect = 0.0, Method: Compositional matrix adjust. Identities = 563/1326 (42%), Positives = 745/1326 (56%), Gaps = 203/1326 (15%) Query: 65 LAAAQVIVLRVLGRLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQ 124 LA A ++V+R+LG A Q + V A G +++SG D EL ST A Sbjct: 43 LAEASIVVIRILGGYRAWQ---SGIDTVIAGGVPAVLVSGEQAADAELTDRSTVAAGTAL 99 Query: 125 QALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAGIADWLAL 184 QA Y GG NL ++ L D +L++G+G+ P A P G+ Sbjct: 100 QAHIYLAHGGVDNLRELHAFLCDTVLMTGFGFTPPVATPTWGVLE--------------- 144 Query: 185 RAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAGGGQAL 244 R A P + +++YRA L+GNT +++AL A+E G LP++ +SLR A Sbjct: 145 RPDAGKTGPTIAVLYYRAQHLAGNTGYVEALCRAIEDAGGRPLPLYCASLRT------AE 198 Query: 245 PPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAG---------WSVSVLEQLDLPVLQA 295 P L+ G D ++ T + AGGV PA W+V L LD+P+LQ Sbjct: 199 PRLLERLGGA--DAMVVTV------LAAGGVKPAAASAGGDDDSWNVEHLAALDIPILQG 250 Query: 296 ITSGMTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETTDSGAVQYQPLPDRV 355 + + QW + G++PLD A V +PEFDGRII VP SFKE D G + Y P+R Sbjct: 251 LCLTSPRDQWCANDDGLSPLDVASQVAVPEFDGRIITVPFSFKEIDDDGLISYVADPERC 310 Query: 356 RRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSADG 415 R+AGLA R RLR A+KR+A +F+ +K ++IGNAVGLD P S +A+L+A+ G Sbjct: 311 ARVAGLAVRHARLRQVAPADKRVALVFSAYPTKHARIGNAVGLDTPASAVALLQAMRQRG 370 Query: 416 YAIDALP----QTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSL 471 Y + LP G ALIH L++ +D LTE QL R+ A Y WFA LP L Sbjct: 371 YRVGDLPGVESNDGDALIHALIECGGHDPDWLTEGQLAGNPIRVSAKEYRDWFATLPAEL 430 Query: 472 QDKMQRQWGAAPGQAYVHDQH-----LVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDL 526 D + WG PG+ +V H +VIA L GN + +QPPRG+G +P AIYH PDL Sbjct: 431 TDVVTAYWGPPPGELFVDRSHDPDGEIVIAALRAGNLVLMVQPPRGFGENPVAIYHDPDL 490 Query: 527 PPTHHYYALYRWLD----EEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPL 582 PP+HHY A YRWLD +GAHA+VH+GKHG LEWLPGK +G+S C PDA LGD+PL Sbjct: 491 PPSHHYLAAYRWLDTGFSNGFGAHAVVHLGKHGNLEWLPGKTLGMSASCGPDAALGDLPL 550 Query: 583 FYPFIINDPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSK 642 YPF++NDPGEG+QAKRRAHAV+VDHL PPM A++YG +A+L QL+DE+ V LDP K Sbjct: 551 IYPFLVNDPGEGTQAKRRAHAVLVDHLIPPMARAETYGDIARLEQLLDEHASVAALDPGK 610 Query: 643 LPLLQQQIWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHA 702 LP ++QQIW L+R +D HD G Sbjct: 611 LPAIRQQIWTLIRAAKMD-----------------------------------HDLGLTE 635 Query: 703 HHDHDHAHEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQM 762 + D + ++ +DG+LCE+ QIRDGLHILG+ P Q Sbjct: 636 RPEEDSFDD------------------MLLHVDGWLCEIKDVQIRDGLHILGQNPTGEQE 677 Query: 763 PDMLVALTRLPN-----QDLPGLQEEVARLFGLSLDMLLEHKGRRLNIDDALARCADRPI 817 D+++A+ R +PGL++ GL+ D E R +D Sbjct: 678 LDLVLAILRARQLFGGAHAIPGLRQA----LGLAEDGTDE----RATVDQ---------- 719 Query: 818 VTRADALEAIDALCLRLMQALQEHDFAPTAIDGVLGSVFAALEQASPEQRPRLQPAMSQA 877 T A A E L+ ALQ + P+A D + G+ AA Sbjct: 720 -TEAKARE--------LVAALQATGWDPSAADRLTGNADAA------------------- 751 Query: 878 ATSVLGXRLQPAMSQAATSVLPSRRAADTGAVRCVLAFACEELVPRLHRTSEEIGNLLNG 937 VL FA E++PRL T+ EI +L Sbjct: 752 ---------------------------------AVLRFAATEVIPRLAGTATEIEQVLRA 778 Query: 938 LRGGYIPAGPSGSPTRGMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLAREVLQRHHRET 997 L G +IPAGPSGSP RG+ ++LPTGRNFYSVDP++VPS+ AW G LA +L R+ E Sbjct: 779 LDGRFIPAGPSGSPLRGLVNVLPTGRNFYSVDPKAVPSRLAWEAGVALADSLLARYRDEH 838 Query: 998 GHYPESVAISIWGTSAMRTHGDDVAQILWLMGARPLWRAGNRQVAGVELVPLE--ELQRP 1055 G +P SV +S+WGTSAMRT GDD+A++L L+G RP+W +R+V ++L P++ EL RP Sbjct: 839 GRWPRSVGLSVWGTSAMRTAGDDIAEVLALLGVRPVWDDASRRV--IDLAPMQPAELGRP 896 Query: 1056 RIDVTTRISGFFRDAFPQLIELIDDAVQLAIAADEPETMNFVRKHYLHDLAQGMGAGLGQ 1115 RIDVT RISGFFRDAFP ++ ++DDAV+L DE N+VR H DLA G Sbjct: 897 RIDVTVRISGFFRDAFPHVVTMLDDAVRLVADLDEAAEDNYVRAHAQADLAHH-----GD 951 Query: 1116 AEAAAQASYRVFGAKPGSYGAGILPLIQEKNWQDQADFAEAYINWGGFAYGRKVQGADQR 1175 +A+ R+FG+KPG+YGAG+L LI ++W+D AD A+ Y WGGFAYGR + G + Sbjct: 952 QR---RATTRIFGSKPGTYGAGLLQLIDSRSWRDDADLAQVYTAWGGFAYGRDLDGREAI 1008 Query: 1176 DAFRQRLAGVQVALHNQDNHEHDIFDSDDYLQYHGGMIATIRALSGQQPRHYFGDSHDPQ 1235 D ++ + VA N D EHDI DSDDY QYHGGM+AT+RAL+GQ P Y GD+ P Sbjct: 1009 DDMNRQYRRIAVAAKNTDTREHDIADSDDYFQYHGGMVATVRALTGQAPAAYIGDNTRPD 1068 Query: 1236 RAAVRDLKEETLRVFRARVVNPKWLASIQRHGYKGGLELSATVDYLFGYDATAQVLDDWM 1295 R L EET RVFRARVVNP+W+A+++RHGYKG E++ATVDYLFGYDATA V+ DWM Sbjct: 1069 AIRTRTLSEETTRVFRARVVNPRWMAAMRRHGYKGAFEMAATVDYLFGYDATAGVMADWM 1128 Query: 1296 YQQLAETYGFDPAMRQFLEEANPWAQNAIAERLLEAASRGMWQAPDAQTLERLRQLYLHS 1355 Y+QL + Y D R F+ E+NPWA + +AERLLEAA RG+W P +TL+ LRQ+ L + Sbjct: 1129 YEQLTQRYVLDAQNRTFMTESNPWALHGMAERLLEAAGRGLWAQPAPETLDGLRQVLLET 1188 Query: 1356 ETLLEA 1361 E LEA Sbjct: 1189 EGDLEA 1194 >alr1689 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Nos Nostoc sp. PCC 7120 Length = 1302 Score = 960 bits (2482), Expect = 0.0, Method: Compositional matrix adjust. Identities = 554/1386 (39%), Positives = 767/1386 (55%), Gaps = 137/1386 (9%) Query: 6 ARIALLTHAPTDLAMLATARAQLPADFPAVAGYDLQRLQAADQDQASQWPSLAALLRGEL 65 A L+T A TD+ LA A +LPA FPA+ +L LQ Q S+ L Sbjct: 25 APFVLITAADTDIQTLAAAVPKLPATFPAIRVANLLLLQ--------QQISIDTYAEQVL 76 Query: 66 AAAQVIVLRVLG-RLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQ 124 AQVI+LR+LG R G + +V G LIV+ G DPEL + STAP Sbjct: 77 ELAQVIILRLLGGRSYWAYGLEVVQEIVERTGITLIVMPGDDALDPELISQSTAPVGTVN 136 Query: 125 QALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYH----PDLEQDAGI-A 179 Q YF GG N+ L+ +SD L + Y Q +P GLY + + D G Sbjct: 137 QIWQYFYEGGVENIVNALQLISDVSLKTTYKPPAPQRVPRVGLYEWGMGTNRQGDKGNEV 196 Query: 180 DWLALRAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAG 239 ++ +Q+ P VGI+FYRAH+L+GN IDAL AAL R L +PVF SSLR Sbjct: 197 EFSPTSSQSLI--PKVGILFYRAHYLAGNIQVIDALCAALWQRNLQPVPVFISSLRDPDV 254 Query: 240 GGQALPPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAGWSVSVLEQLDLPVLQAITSG 299 + L Q + Q+ L++NTTSF++ + W E+LD+PVLQ I SG Sbjct: 255 QAE-LIDFFQPKDSQQISLLLNTTSFSLARLETEAPQTELW-----EKLDVPVLQVILSG 308 Query: 300 MTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETT------DSGAVQYQPLPD 353 QW+ G++P D AMNV LPE DGRII +SFK ++ V Y+P+ D Sbjct: 309 GFVEQWEAQLNGLSPRDIAMNVALPEVDGRIISRAVSFKAIQTRNPDLETDVVVYEPISD 368 Query: 354 RVRRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSA 413 R+ +A LA V LRS P +RIA I N ++ ++ N VGLD PES + +L+AL Sbjct: 369 RIDFVAQLAANWVHLRSQPPQQRRIALILANYPNRDGRLANGVGLDTPESCVEILKALQQ 428 Query: 414 DGYAIDALPQTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSLQ- 472 GY + LP G LI L + D ++R + + Y ++FA LP ++Q Sbjct: 429 SGYVVSNLPANGDELIQLLTAGVTNDP---EGREIRPVQQSLSSEEYQEYFAGLPATVQQ 485 Query: 473 ---DKMQRQWGAAPGQAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPT 529 ++ R WG + I G+ GN FV +QP RGY +DP+ YH PDL PT Sbjct: 486 GINERWGRDWGLGEQASNFPSSSCPIPGIQFGNVFVGIQPSRGYDIDPNLNYHAPDLEPT 545 Query: 530 HHYYALYRWLDEEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFYPFIIN 589 H Y A Y W+ E +GA A+VHVGKHG LEWLPGK + LS C+P+A+ G MP YPFI+N Sbjct: 546 HAYLAFYYWVRESFGADAVVHVGKHGNLEWLPGKSLALSSNCYPEAVFGPMPHLYPFIVN 605 Query: 590 DPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLPLLQQQ 649 DPGEGSQAKRRA AV++DHLTPPMT A+ YGAL +L LVDEYY+ E LDPS+L +++ + Sbjct: 606 DPGEGSQAKRRAQAVIIDHLTPPMTRAELYGALQKLENLVDEYYEAESLDPSRLGVIRDR 665 Query: 650 IWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHAHHDHDHA 709 I +LV Q NL YK L + + D + Sbjct: 666 IRDLVIQENL-----YKDLGIEKEEDIVNFE----------------------------- 691 Query: 710 HEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQMPDMLVAL 769 + ++ LDGYLCEL AQIRDGLHI G+ P Q+ D++VA+ Sbjct: 692 ------------------SLILNSLDGYLCELKEAQIRDGLHIFGQCPQGRQLRDLIVAI 733 Query: 770 TRLPNQDLPGLQEEVARLFGLSLDMLLEHKGRRLNIDDA--LARCADRPIVTRADALEAI 827 R+PN+ G+ +A ++GL D L ++ L+ D LA P T DA+ A+ Sbjct: 734 ARIPNRYSTGITRALANVWGLDFDPLTDNFSTPLSTQDQKLLAAKTPNPCRTVGDAVTAL 793 Query: 828 DALCLRLMQALQEHDFAPTAIDGVLGSVFAALEQASPEQRPRLQPAMSQAATSVLGXRLQ 887 + L++ L PTA PE RP P ++ + Sbjct: 794 EEHAALLVEQLIN---PPTA----------------PEVRPEGNPPCDFSSCPL------ 828 Query: 888 PAMSQAATSVLPSRRAADTGAVRCVLAFACEELVPRLHRTSEEIGNLLNGLRGGYIPAGP 947 ++ + VL + +L+P L +T EI NLL+GL GGYIP+ Sbjct: 829 ------------PSSSSPPAPLNTVLNWIKSKLLPSLQQTHAEITNLLHGLDGGYIPSAA 876 Query: 948 SGSPTRGMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLAREVLQRHHRETGHYPESVAIS 1007 SG+PTRG +LPTGRNFY+VD R++P+++AW +G++ A +++ + +E G YP+++ +S Sbjct: 877 SGAPTRGRPEVLPTGRNFYAVDIRAIPTETAWDIGRKAAENLVECYTQEHGEYPKTLGLS 936 Query: 1008 IWGTSAMRTHGDDVAQILWLMGARPLWRAGNRQVAGVELVPLEELQRPRIDVTTRISGFF 1067 +WGT+ MRT GDD+A+ L L+G +P+W R+V ++++PL L RPR+DVT RISGFF Sbjct: 937 VWGTATMRTGGDDIAEALALLGVQPVWDGAARRVVDLDILPLSILGRPRVDVTLRISGFF 996 Query: 1068 RDAFPQLIELIDDAVQLAIAADEPETMNFVRKHYLHDLAQGMGAGLGQAEAAAQASYRVF 1127 RDAFP L++L + AV A DEP N + D + GL A ++ YR+F Sbjct: 997 RDAFPNLMDLFEQAVNAVAALDEPPEQNPLAAQIRQDTDFWIQQGLTPETAFERSRYRLF 1056 Query: 1128 GAKPGSYGAGILPLIQEKNWQDQADFAEAYINWGGFAY--GRKVQGADQ---------RD 1176 G+KPG+YGAG+ LI+ +NWQ+ D A AYINW +AY G+ + + + Sbjct: 1057 GSKPGAYGAGLQGLIESQNWQNDQDLANAYINWSCYAYSSGKSQEAGTEINPPSPIPSPE 1116 Query: 1177 AFRQRLAGVQVALHNQDNHEHDIFDSDDYLQYHGGMIATIRALSGQQPRHYFGDSHDPQR 1236 AF QRL +Q+ L NQDN EHD+ DSDDY Q+ GG+ A IR+L G+ P YFGD+ P + Sbjct: 1117 AFTQRLGQMQIVLQNQDNREHDLLDSDDYYQFQGGLTAAIRSLQGKNPETYFGDNSIPSQ 1176 Query: 1237 AAVRDLKEETLRVFRARVVNPKWLASIQRHGYKGGLELSATVDYLFGYDATAQVLDDWMY 1296 VR L+EE RV+R+RVVNPKW+ + RHGYKG E++ATVD+LF YDAT + ++D+MY Sbjct: 1177 PRVRQLREEIARVYRSRVVNPKWIEGMMRHGYKGAFEMAATVDFLFAYDATTRCVEDYMY 1236 Query: 1297 QQLAETYGFDPAMRQFLEEANPWAQNAIAERLLEAASRGMWQAPDAQTLERLRQLYLHSE 1356 Q + + Y DP + ++E NP A IAERLLEA RG+W+ + +TLE LR L +E Sbjct: 1237 QGVMQAYLLDPVVCTYIENKNPHALRDIAERLLEANQRGLWENVNIETLENLRNLVHQAE 1296 Query: 1357 TLLEAR 1362 +EA+ Sbjct: 1297 ATIEAK 1302 >slr1211 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Syn Synechocystis Length = 1092 Score = 872 bits (2252), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/1178 (39%), Positives = 677/1178 (57%), Gaps = 117/1178 (9%) Query: 194 AVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLR---VSAGGGQALPPALQY 250 + IIFYR+H+LSGNT IDAL ALE L+ L ++ SSLR V A L Q Sbjct: 9 TIAIIFYRSHYLSGNTTPIDALCQALEKHNLNPLAIYVSSLREPDVQAEILAILENLDQP 68 Query: 251 FGAGQVDLIINTTSFAMGEIT--AGGVTPAGWSVSVLEQLDLPVLQAITSGMTQAQWQHS 308 GA I+NTTSF++ ++ G + + + ++L++PVLQ I SG + QWQ Sbjct: 69 LGA-----ILNTTSFSLAKLQRQIGNLE----MIPLWQKLNVPVLQVILSGGDRQQWQEG 119 Query: 309 TRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETT------DSGAVQYQPLPDRVRRIAGLA 362 RG+NP D AMNV LPE DGRII +SFK ++ Y+P+ DRV IA L Sbjct: 120 LRGLNPRDLAMNVALPEVDGRIITRAISFKAMAARHPQLETEVAIYEPVLDRVEWIAELT 179 Query: 363 QRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSADGYAIDALP 422 + ++ T ++IA I N +K ++ N VGLD P S + +L AL GY + A+P Sbjct: 180 KNIINCAQTEIFQRKIALILANYPNKDGRLANGVGLDTPASCLQILEALKIAGYHLSAIP 239 Query: 423 QTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSLQDKMQRQWGAA 482 + LI +L + D L Q R I + Q+F +LP S+Q M +W Sbjct: 240 KDTETLIKQLTQGVTNDQELA---QYRTVNQTIVTEKVWQFFYSLPQSVQQAMTERWQVR 296 Query: 483 PGQAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLDEE 542 + DQ I+G+ GN FV +QP RGY DP YH PDL PT HY A Y WL +E Sbjct: 297 ENWDNLPDQ-FAISGIQFGNIFVGIQPARGYDFDPSLNYHAPDLEPTLHYLAFYLWLRQE 355 Query: 543 WGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFYPFIINDPGEGSQAKRRAH 602 + A AI+H+GKHG LEWLPGK V LSD C P+ LG +P FYPFI+NDPGEG+QAKRR+ Sbjct: 356 FSAQAIIHLGKHGNLEWLPGKSVVLSDHCHPEIALGPLPNFYPFIVNDPGEGTQAKRRSQ 415 Query: 603 AVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLPLLQQQIWELVRQTNLDTD 662 A ++DHLTPP+T A+ YG L +L L+DEYY+ + LDP+++ + ++ +L+ +NL TD Sbjct: 416 ACIIDHLTPPLTRAELYGDLEKLEALIDEYYEAQALDPTRVKTIGDRLRKLLATSNLQTD 475 Query: 663 LQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHAHHDHDHAHEEGELPHALTEL 722 L G P AL +L Sbjct: 476 L-------------------------------------------------GLTPPALKDL 486 Query: 723 DGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQMPDMLVALTRLPNQDLPGLQE 782 L+ D YLCEL AQIRDGLHILG+TP Q+ D+ +++ R P+ GL + Sbjct: 487 QP-----LLTSADSYLCELKEAQIRDGLHILGQTPTGEQLRDLAISIARSPSYQRLGLTQ 541 Query: 783 EVARLFGLSLDMLLEHKGRRLNIDDALARCADRPIVTRADALEAIDALCLRLMQALQEHD 842 +A L D +L+ + + + +T+ + L + + Sbjct: 542 AIAFDLELEFDPVLDDPNEPWQLSSTMQMKLQQWELTQ----------FIELFNSCR--- 588 Query: 843 FAPTAIDGVLGSVFAALEQASPEQRPRLQPAMSQAATSVLGXRLQPAMSQAATSVLPSRR 902 + G V LE+ A ++G L+ + ++ + Sbjct: 589 --------IGGQVIEILEEI---------------AKQLVGSLLEIVIVDQKVNLFFQKP 625 Query: 903 AADTGAVRCVLAFACEELVPRLHRTSEEIGNLLNGLRGGYIPAGPSGSPTRGMAHILPTG 962 + T + L + + L+P L +T +EI NLL GL G YI +GP+G+P+RG +LPTG Sbjct: 626 DSKT---KSNLDYIEQTLLPMLQQTPQEITNLLRGLNGEYIASGPAGAPSRGRPDVLPTG 682 Query: 963 RNFYSVDPRSVPSQSAWRVGQQLAREVLQRHHRETGHYPESVAISIWGTSAMRTHGDDVA 1022 RNFY+VD R++P+++AW +G++ A +++R+ ++ G YP+++AISIWGTS MRT GDD+A Sbjct: 683 RNFYAVDIRAIPTETAWDIGRRAAETLIERYTQDHGEYPQTLAISIWGTSTMRTGGDDIA 742 Query: 1023 QILWLMGARPLWRAGNRQVAGVELVPLEELQRPRIDVTTRISGFFRDAFPQLIELIDDAV 1082 Q+L L+G +P+W + +R++ E++P L+RPR+DVT RISGFFRD+FP L+E + A+ Sbjct: 743 QVLALLGVQPVWDSPSRRIVDFEILPTTVLKRPRVDVTIRISGFFRDSFPNLVEFLHQAI 802 Query: 1083 QLAIAADEPETMNFVRKHYLHDLAQGMGAGLGQAEAAAQASYRVFGAKPGSYGAGILPLI 1142 DEP +N + + + Q GL EA +A+YR+FG+KPG+YGAG+ LI Sbjct: 803 AAVSQLDEPANLNPLAEKVKQETEQWQQLGLATEEAVTKATYRIFGSKPGAYGAGLQGLI 862 Query: 1143 QEKNWQDQADFAEAYINWGGFAYGRKVQGADQRDAFRQRLAGVQVALHNQDNHEHDIFDS 1202 + +NWQD +D A AY+NW +AY R+ G +Q + F QRL +Q+ LHNQDN EHD+ DS Sbjct: 863 EAQNWQDDSDLARAYLNWSCYAYDRQGVGHNQPEVFAQRLQNLQIVLHNQDNREHDLLDS 922 Query: 1203 DDYLQYHGGMIATIRALSGQQPRHYFGDSHDPQRAAVRDLKEETLRVFRARVVNPKWLAS 1262 DDY Q+ GG+ A +R+L+G+ P YFGD+ +P + V+ L +E +V+R+RVVNPKW+A Sbjct: 923 DDYYQFQGGLTAAVRSLTGKNPTVYFGDNSNPAQPKVKLLTQEIAKVYRSRVVNPKWIAG 982 Query: 1263 IQRHGYKGGLELSATVDYLFGYDATAQVLDDWMYQQLAETYGFDPAMRQFLEEANPWAQN 1322 + RHGYKG E++AT+DYLF YDATA ++D+MY +A+ Y D +++F+++ NPWA Sbjct: 983 VMRHGYKGAFEMAATLDYLFAYDATAHCVEDFMYTGIAQAYLLDEEVQKFVQQHNPWALR 1042 Query: 1323 AIAERLLEAASRGMWQAPDAQTLERLRQLYLHSETLLE 1360 +AERLLEA R +W D Q L++LR + +E +LE Sbjct: 1043 DMAERLLEAEQRQLWSNVDPQLLDQLRAIAHGAEEILE 1080 >RSp0626 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Rso Ralstonia solanacearum Length = 1379 Score = 851 bits (2199), Expect = 0.0, Method: Compositional matrix adjust. Identities = 428/663 (64%), Positives = 508/663 (76%), Gaps = 18/663 (2%) Query: 8 IALLTHAPTDLAMLATARAQLPADFPAVAGYDLQRLQAADQDQASQWPSLAALLRGELAA 67 I LLTHA TDL+ L A AQLP F V G LQ A D A +A LL G +A Sbjct: 9 IVLLTHAGTDLSTLQRATAQLPDGFAGVTGLHLQ----AIGDDAR----MADLLAGPIAG 60 Query: 68 AQVIVLRVLGRLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQQAL 127 A+++++RVLGRL A+ G +L RA+GR L+++SGTGEPDPELAA ST P +QQ+ Sbjct: 61 ARIVIVRVLGRLQAIPGIDALLHDTRAQGRALVIVSGTGEPDPELAARSTVPPALQQEVA 120 Query: 128 AYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAGIADWLALRAQ 187 AY GG+ NLAQ+LRCLSDRLL++G+GY+P ALPEHG+YHP+L A + DW A+R Sbjct: 121 AYLQAGGTGNLAQLLRCLSDRLLMTGFGYQPPMALPEHGIYHPELAAPATLDDWAAIRNP 180 Query: 188 APAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAGGGQALPPA 247 A P VGI FYRAHWL GNT FID LV AL + L+ LPV+T+SLR G +P A Sbjct: 181 A---WPTVGIAFYRAHWLCGNTRFIDQLVDALAEQRLNALPVYTASLRTLDATG--MPAA 235 Query: 248 LQYF---GAGQVDLIINTTSFAMGEITAGGVTPAGWSVSVLEQLDLPVLQAITSGMTQAQ 304 L F G G++D ++NTTSFAMG++ A G T AGWSV+ +LD+PV+QAI S MTQAQ Sbjct: 236 LDVFADDGVGRIDALVNTTSFAMGDVNADGPTAAGWSVAAFTRLDVPVVQAIASSMTQAQ 295 Query: 305 WQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETTDSGAVQYQPLPDRVRRIAGLAQR 364 W S RG+NPLD AMNV LPEFDGRI+ VP+SFK+ D A Y PLPDRVRR+AG+ R Sbjct: 296 WAASERGLNPLDTAMNVALPEFDGRIVSVPMSFKDERDETA--YAPLPDRVRRVAGIVAR 353 Query: 365 LVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSADGYAIDALPQT 424 V LR T A+KRIAF+FTNSSSKASQIGNAVGLD+P SL+ +LRA+ A GY ID LP++ Sbjct: 354 QVALRRTAPADKRIAFLFTNSSSKASQIGNAVGLDSPASLLTLLRAMQAQGYRIDGLPES 413 Query: 425 GTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSLQDKMQRQWGAAPG 484 G ALIH L+DR +YD+ L+ QL +A A +PAARYA WF+ LP LQDKM+++WG APG Sbjct: 414 GDALIHALIDRGAYDEDYLSAAQLEQAIATVPAARYAAWFSDLPAPLQDKMRQRWGDAPG 473 Query: 485 QAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLDEEWG 544 AYVHD LV AG++ GNAFVALQPPRGYGMDPDAIYH PDLPPTHHYYALYRWL +EW Sbjct: 474 NAYVHDGKLVFAGMEYGNAFVALQPPRGYGMDPDAIYHTPDLPPTHHYYALYRWLRDEWR 533 Query: 545 AHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFYPFIINDPGEGSQAKRRAHAV 604 A AIVHVGKHGTLEWLPGKGVG+S CFPDALLGD+PLFYPFI+NDPGEGSQAKRRAHAV Sbjct: 534 ADAIVHVGKHGTLEWLPGKGVGVSQTCFPDALLGDLPLFYPFILNDPGEGSQAKRRAHAV 593 Query: 605 VVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLPLLQQQIWELVRQTNLDTDLQ 664 ++DHLTPPMTTAD+YG LAQLTQLVDEYYQVE+LDP+KLPLLQQQIW+L+++ LD DL Sbjct: 594 IIDHLTPPMTTADTYGPLAQLTQLVDEYYQVEMLDPAKLPLLQQQIWDLIKEARLDADLA 653 Query: 665 YKL 667 L Sbjct: 654 AML 656 Score = 820 bits (2119), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/654 (62%), Positives = 478/654 (73%), Gaps = 45/654 (6%) Query: 715 LPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQMPDMLVALTRLPN 774 +P +L ++DG VAHLIED+DGYLCELGAAQIRDGLH+LGR P + DM+ A+ RLPN Sbjct: 769 VPLSLAKMDGVDVAHLIEDIDGYLCELGAAQIRDGLHVLGRVPADDALVDMVCAMVRLPN 828 Query: 775 QDLPGLQEEVARLFGLSLDMLLEHKGRRLN-IDDALARCADRPIVTRADALEAIDALCLR 833 +P L VA GL+ D L KG+RL + L R ADRP+VTRADAL+A+ AL Sbjct: 829 LGVPSLPAGVAEALGLAWDALQHDKGKRLEAVSPPLQRLADRPLVTRADALDAVSALTRA 888 Query: 834 LMQALQEHDFAPTAIDGVLGSVFAALEQASPEQRPRLQPAMSQAATSVLGXRLQPAMSQA 893 L+ AL EH F T D L SV + Sbjct: 889 LIAALAEHGFDATRSDAALASVLPGI---------------------------------- 914 Query: 894 ATSVLPSRRAADTGAVRCVLAFACEELVPRLHRTSEEIGNLLNGLRGGYIPAGPSGSPTR 953 A TGA+R LAF C ELVP L RT+EEIGNLL+GL GGY+PAGPSG+PTR Sbjct: 915 ----------AHTGAIRQTLAFVCRELVPNLARTTEEIGNLLHGLAGGYVPAGPSGAPTR 964 Query: 954 GMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLAREVLQRHHRETGHYPESVAISIWGTSA 1013 GMAH+LPTGRNFYSVDPRS+PSQ+AWR+G LA E L RH ETGH PESV+IS+WGTSA Sbjct: 965 GMAHVLPTGRNFYSVDPRSLPSQAAWRIGTALANEALARHRTETGHDPESVSISVWGTSA 1024 Query: 1014 MRTHGDDVAQILWLMGARPLWRAGNRQVAGVELVPLEELQRPRIDVTTRISGFFRDAFPQ 1073 MRTHGDD+AQIL L+G RP W+A +R+VAG+E++PL EL RPRIDVT RISGFFRDAFP Sbjct: 1025 MRTHGDDIAQILALLGVRPRWQAESRRVAGIEVIPLAELGRPRIDVTVRISGFFRDAFPH 1084 Query: 1074 LIELIDDAVQLAIAADEPETMNFVRKHYLHDLAQGMGAGLGQAEAAAQASYRVFGAKPGS 1133 LI L+D+AV DEP NFVRKHYL DLA + AGL A + YRVFG++PG+ Sbjct: 1085 LIHLVDEAVHTVARLDEPVERNFVRKHYLADLAHQLFAGLPPEAAEQRTLYRVFGSRPGT 1144 Query: 1134 YGAGILPLIQEKNWQDQADFAEAYINWGGFAYGRKVQGADQRDAFRQRLAGVQVALHNQD 1193 YGAGILPLIQE++WQD ADFA+AYINWGG+AYGR+ G D R FR RL+GV++ALHNQD Sbjct: 1145 YGAGILPLIQEQHWQDDADFAQAYINWGGYAYGRRDNGTDARADFRHRLSGVEIALHNQD 1204 Query: 1194 NHEHDIFDSDDYLQYHGGMIATIRALSGQQPRHYFGDSHDPQRAAVRDLKEETLRVFRAR 1253 N EHDIFDSDDYLQYHGGMIATIR+L+G+QPR YFGDSH+P AVR LKEETLRVFR+R Sbjct: 1205 NREHDIFDSDDYLQYHGGMIATIRSLTGRQPRQYFGDSHNPDHPAVRSLKEETLRVFRSR 1264 Query: 1254 VVNPKWLASIQRHGYKGGLELSATVDYLFGYDATAQVLDDWMYQQLAETYGFDPAMRQFL 1313 V NPKW+A IQ+HGYKGGLEL+ATVDYLFGYDATA V+DDW+Y+QLA+ Y FDPAM+QFL Sbjct: 1265 VANPKWIAGIQKHGYKGGLELTATVDYLFGYDATAHVVDDWVYEQLAQAYAFDPAMQQFL 1324 Query: 1314 EEANPWAQNAIAERLLEAASRGMWQAPDAQTLERLRQLYLHSETLLEARGETVR 1367 E+NPWA NAI ERLLEA R MW P T+ L+ L+L SE +LEARGET + Sbjct: 1325 AESNPWALNAITERLLEAIQRQMWAEPKPDTVAALQALHLRSEAMLEARGETTQ 1378