BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0335.p (519 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0618_1 [H] COG1010 Precorrin-3B methylase Rso Ralstonia solan... 342 1e-93 RSp0618_2 [H] COG2099 Precorrin-6x reductase Rso Ralstonia solan... 322 9e-88 TVN0921 [H] COG1010 Precorrin-3B methylase Tvo Thermoplasma volc... 189 2e-47 lin1162 [H] COG1010 Precorrin-3B methylase Lin Listeria innocua 179 2e-44 STM2027 [H] COG1010 Precorrin-3B methylase Sty Salmonella typhim... 172 2e-42 >RSp0618_1 [H] COG1010 Precorrin-3B methylase Rso Ralstonia solanacearum Length = 243 Score = 342 bits (877), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 172/242 (71%), Positives = 192/242 (79%) Query: 7 KGVLNLVSVGPGFEEMIIPRAIEALRESEVIVAYELYLRWIAAHIEGKEIHTPPLTQERE 66 G L LVSVGPG E+I P AL ++VIVAY+LYL WIA I K+I T PLTQER Sbjct: 2 SGKLYLVSVGPGTRELIPPMVKTALDAADVIVAYDLYLTWIAPWITAKDIRTLPLTQERG 61 Query: 67 RALLAIEQARAGRRVALISSGDIGIYAMAALAFDDMREDDTYEVNVIPGVTSANACASLL 126 RA LAI +ARAGR VALISSGDIGIYAMAALAF+ M E DT++V VIPG+TSANACASLL Sbjct: 62 RAELAIAEARAGRTVALISSGDIGIYAMAALAFEAMAEHDTFDVQVIPGITSANACASLL 121 Query: 127 GSPLSHDFATLSLSNLLCPWTWIEQRASHIAQADLACVLYNVQSAGRQEGVYRILQLMLQ 186 GSPLSHDFATLSLS+LLCPW WIE RA HIAQADLA VLYNVQS RQEGVYRIL ++L+ Sbjct: 122 GSPLSHDFATLSLSDLLCPWAWIETRARHIAQADLAVVLYNVQSRQRQEGVYRILDILLE 181 Query: 187 HKAPHTLCGVVRNAYRPGQKVSIHRLDELPGLQFDMLTSIVIGNRFTQRKRDWIFTPRGY 246 HK TLCG+V NAYR GQ I L EL +FDMLTS+VIGNRFT+RKR WI+TPRGY Sbjct: 182 HKRAETLCGIVHNAYRDGQAAEIVTLAELRTRRFDMLTSLVIGNRFTRRKRGWIYTPRGY 241 Query: 247 ND 248 + Sbjct: 242 GN 243 >RSp0618_2 [H] COG2099 Precorrin-6x reductase Rso Ralstonia solanacearum Length = 276 Score = 322 bits (826), Expect = 9e-88, Method: Compositional matrix adjust. Identities = 168/268 (62%), Positives = 195/268 (72%) Query: 249 WSEESQAEEVAQLPSQAVWVFAGTSDGNALAAELAGQGRPVVVSTATGYGGELARSDCPG 308 W + A LP+ AVWVF+GTSDGNALA ++A GR VVVS+A+ YG LA +CPG Sbjct: 1 WDDTPDTVTAAGLPAHAVWVFSGTSDGNALARDIAATGRAVVVSSASDYGAALAGQNCPG 60 Query: 309 AFVWSGRQGLEARRQALRDSRARVLVDATHPFAVQMSQQLMTLSQELGIPYLRYERPGEL 368 V +GR G+E RR+ LR+S A +VDATHP+A +MSQQL+ L+QEL +PYLRYERPG+ Sbjct: 61 VAVVAGRLGIERRRELLRESAAHAIVDATHPYAAEMSQQLIRLAQELALPYLRYERPGDA 120 Query: 369 AADDPHACADMEDAAHKAMAMGQRIFLATGSKDLATFLQAPGAQERQWFARVTADPDFIS 428 A A MEDAA AM G+RIFLATGSKDLATF+ A A WF RV DP + Sbjct: 121 QAAPAQRAASMEDAARLAMQHGRRIFLATGSKDLATFVNADAAGRHAWFVRVAPDPAHLQ 180 Query: 429 RALELGLPRAHLCAMQGPFSQAFNEALWRDWGIDCVVTKDSGEAGGYHAKAEAARALGIP 488 RA++ G+PRA L AMQGPFSQA NEALWRDWGIDCVVTKDSGEAGGYHAKA AA ALGIP Sbjct: 181 RAIDAGIPRARLVAMQGPFSQAANEALWRDWGIDCVVTKDSGEAGGYHAKAAAAAALGIP 240 Query: 489 LLTVRRPPLDYPQVAHDFGSVHAHLAAL 516 L+ V RP +DYP VAHDF V LA L Sbjct: 241 LIVVDRPAIDYPAVAHDFAGVLMQLADL 268 >TVN0921 [H] COG1010 Precorrin-3B methylase Tvo Thermoplasma volcanium Length = 251 Score = 189 bits (479), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 97/240 (40%), Positives = 149/240 (62%), Gaps = 2/240 (0%) Query: 10 LNLVSVGPGFEEMIIPRAIEALRESEVIVAYELYLRWIAAHIEGKEIHTPPLTQERERAL 69 L +V +GPG +++ P+A A+ SE ++ + LY+ +I K + + E ERA Sbjct: 5 LFVVGIGPGSNDLMTPQASLAIERSEYVIGFSLYVSFIKEKFPNKIYISNGMQGEIERAK 64 Query: 70 LAIEQARAGRRVALISSGDIGIYAMAALAFDDMR--EDDTYEVNVIPGVTSANACASLLG 127 AIE AR+G V++ISSGD GIY +A F+ + ED+ EV+V+PG+++ ++CASLLG Sbjct: 65 KAIELARSGHNVSIISSGDAGIYGIAGAVFEILSTLEDNMPEVSVVPGISALSSCASLLG 124 Query: 128 SPLSHDFATLSLSNLLCPWTWIEQRASHIAQADLACVLYNVQSAGRQEGVYRILQLMLQH 187 SPLS+DF LSLS+LL PW I +RA A DL V+YN + + + ++++ L++ Sbjct: 125 SPLSNDFMVLSLSDLLTPWEVIRKRAEAAAILDLVTVIYNPRGSRFPNNLEKVMEYFLKY 184 Query: 188 KAPHTLCGVVRNAYRPGQKVSIHRLDELPGLQFDMLTSIVIGNRFTQRKRDWIFTPRGYN 247 ++ T G+VRNAYRP Q I +L + + DMLT+++IGN T W+ T RGY+ Sbjct: 185 RSGDTPVGIVRNAYRPDQSAKIVQLKDFSCSEIDMLTTVIIGNSETYVSGRWMATRRGYS 244 >lin1162 [H] COG1010 Precorrin-3B methylase Lin Listeria innocua Length = 241 Score = 179 bits (453), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 86/240 (35%), Positives = 147/240 (61%), Gaps = 1/240 (0%) Query: 9 VLNLVSVGPGFEEMIIPRAIEALRESEVIVAYELYLRWIAAHIEGKEIHTPPLTQERERA 68 ++ ++ +GPG + ++ A+EA+ +++VIV Y Y++ I I+ KE+ + +E +R Sbjct: 1 MIYVIGIGPGDKRLMTGEALEAIADADVIVGYVTYIKLIKELIKDKEVVKTGMRREIDRC 60 Query: 69 LLAIEQARAGRRVALISSGDIGIYAMAALAFD-DMREDDTYEVNVIPGVTSANACASLLG 127 A+ A G++VA++SSGD GIY MA L + + + EV VIPG+T++ A++LG Sbjct: 61 QEAVNIALTGKKVAVVSSGDAGIYGMAGLVLELAEKSNPELEVKVIPGITASIGAAAVLG 120 Query: 128 SPLSHDFATLSLSNLLCPWTWIEQRASHIAQADLACVLYNVQSAGRQEGVYRILQLMLQH 187 +P+ HDF +SLS+L+ PW IE+R +H A AD YN +S GR + Q M++H Sbjct: 121 APIMHDFCHISLSDLMTPWEVIEKRLTHAAMADFVVCFYNPRSKGRANHLANAFQKMMEH 180 Query: 188 KAPHTLCGVVRNAYRPGQKVSIHRLDELPGLQFDMLTSIVIGNRFTQRKRDWIFTPRGYN 247 K+P T+ G+V++ R ++ I ++++ DM T +++GN+ T K + TPRGY+ Sbjct: 181 KSPKTVVGIVKDVGRKEERKIITTMEDIDYELVDMTTMVIVGNKETYVKNGKMITPRGYS 240 >STM2027 [H] COG1010 Precorrin-3B methylase Sty Salmonella typhimurium LT2 Length = 241 Score = 172 bits (435), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 93/240 (38%), Positives = 143/240 (59%), Gaps = 1/240 (0%) Query: 9 VLNLVSVGPGFEEMIIPRAIEALRESEVIVAYELYLRWIAAHIEGKEIHTPPLTQERERA 68 +L+++ +GPG + M+ AIEAL+ +E++V Y+ Y + A K++ + +E ER Sbjct: 1 MLSVIGIGPGSQAMMTMEAIEALQAAEIVVGYKTYTHLVKAFTGDKQVIKTGMCREIERC 60 Query: 69 LLAIEQARAGRRVALISSGDIGIYAMAALAFDDM-REDDTYEVNVIPGVTSANACASLLG 127 AIE A+AG VALISSGD GIY MA L + + ++ EV +IPG+T++ A ASLLG Sbjct: 61 QAAIELAQAGHNVALISSGDAGIYGMAGLVLELVSKQKLDVEVRLIPGMTASIAAASLLG 120 Query: 128 SPLSHDFATLSLSNLLCPWTWIEQRASHIAQADLACVLYNVQSAGRQEGVYRILQLMLQH 187 +PL HDF +SLS+LL PW IE+R +AD YN +S GR+ + R L+ Sbjct: 121 APLMHDFCHISLSDLLTPWPVIEKRIVAAGEADFVICFYNPRSRGREGHLARAFDLLAAS 180 Query: 188 KAPHTLCGVVRNAYRPGQKVSIHRLDELPGLQFDMLTSIVIGNRFTQRKRDWIFTPRGYN 247 K+ T GVV++A R ++ + L ++ DM + +++GN+ T + + TPRGY Sbjct: 181 KSAQTPVGVVKSAGRKKEEKWLTTLGDMDFEPVDMTSLVIVGNKTTYVQDGLMITPRGYT 240