BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0311.p (343 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3366 [R] COG0388 Predicted amidohydrolase Pae Pseudomonas aeru... 567 e-161 HP0294 [R] COG0388 Predicted amidohydrolase Hpy Helicobacter pyl... 541 e-154 jhp0279 [R] COG0388 Predicted amidohydrolase jHp Helicobacter py... 539 e-153 HP1238 [R] COG0388 Predicted amidohydrolase Hpy Helicobacter pyl... 219 8e-57 jhp1159 [R] COG0388 Predicted amidohydrolase jHp Helicobacter py... 214 3e-55 >PA3366 [R] COG0388 Predicted amidohydrolase Pae Pseudomonas aeruginosa Length = 346 Score = 567 bits (1461), Expect = e-161, Method: Compositional matrix adjust. Identities = 264/340 (77%), Positives = 295/340 (86%) Query: 1 MRHGDISSSKDAVGVAVVNYKMPRLHTRCEVLENAQKIAAMLVGMKQGLPGLDLVVFPEY 60 MRHGDISSS D VGVAVVNYKMPRLHT EVL+NA+KIA M+VGMKQGLPG+DLVVFPEY Sbjct: 1 MRHGDISSSNDTVGVAVVNYKMPRLHTAAEVLDNARKIAEMIVGMKQGLPGMDLVVFPEY 60 Query: 61 STHGIMYDREEMFETAAAIPGDETRIFSEACRIAGVWGVFSLTGERHEEHPRKVPYNTLI 120 S GIMYD EM ETA AIPG+ET IFS ACR A VWGVFSLTGERHEEHPRK PYNTL+ Sbjct: 61 SLQGIMYDPAEMMETAVAIPGEETEIFSRACRKANVWGVFSLTGERHEEHPRKAPYNTLV 120 Query: 121 LINDQGEIVQKYRKIMPWTPIEGWYPGDATYVCDGPKGLKISLIICDDGNYPEIWRDCAM 180 LI++ GEIVQKYRKI+PW PIEGWYPG TYV +GPKG+KISLIICDDGNYPEIWRDCAM Sbjct: 121 LIDNNGEIVQKYRKIIPWCPIEGWYPGGQTYVSEGPKGMKISLIICDDGNYPEIWRDCAM 180 Query: 181 KGAELVVRCQGYMYPAKEQQIMVSKAMAWMNNLYVAVANAAGFDGVYSYFGHSAIVGFDG 240 KGAEL+VRCQGYMYPAK+QQ+M++KAMAW NN YVAVANAAGFDGVYSYFGHSAI+GFDG Sbjct: 181 KGAELIVRCQGYMYPAKDQQVMMAKAMAWANNCYVAVANAAGFDGVYSYFGHSAIIGFDG 240 Query: 241 RTLGECGTEEMGIQYAELSISAIRDARRNWQSQNHLYKLLHRGYTGKINSGESPAGVAEC 300 RTLGECG EEMGIQYA+LS+S IRDAR N QSQNHL+K+LHRGY+G SG+ G+AEC Sbjct: 241 RTLGECGEEEMGIQYAQLSLSQIRDARANDQSQNHLFKILHRGYSGLQASGDGDRGLAEC 300 Query: 301 PFDFYRTWVNDPQAARAQVEALTRNSAGTPECPMPGIPIE 340 PF+FYRTWV D + AR VE LTR++ G +CP+ +P E Sbjct: 301 PFEFYRTWVTDAEKARENVERLTRSTTGVAQCPVGRLPYE 340 >HP0294 [R] COG0388 Predicted amidohydrolase Hpy Helicobacter pylori 26695 Length = 339 Score = 541 bits (1395), Expect = e-154, Method: Compositional matrix adjust. Identities = 249/340 (73%), Positives = 290/340 (85%), Gaps = 1/340 (0%) Query: 1 MRHGDISSSKDAVGVAVVNYKMPRLHTRCEVLENAQKIAAMLVGMKQGLPGLDLVVFPEY 60 MRHGDISSS D VGVAVVNYKMPRLHT+ EVLEN + IA ++ G+KQGLPGLDL++FPEY Sbjct: 1 MRHGDISSSPDTVGVAVVNYKMPRLHTKNEVLENCRNIAKVIGGVKQGLPGLDLIIFPEY 60 Query: 61 STHGIMYDREEMFETAAAIPGDETRIFSEACRIAGVWGVFSLTGERHEEHPRKVPYNTLI 120 STHGIMYDR+EMF+TAA++PG+ET IF+EAC+ VWGVFSLTGE+HE+ +K PYNTLI Sbjct: 61 STHGIMYDRQEMFDTAASVPGEETAIFAEACKKNKVWGVFSLTGEKHEQ-AKKNPYNTLI 119 Query: 121 LINDQGEIVQKYRKIMPWTPIEGWYPGDATYVCDGPKGLKISLIICDDGNYPEIWRDCAM 180 L+ND+GEIVQKYRKI+PW PIE WYPGD TYV DGPKGLK+SLIICDDGNYPEIWRDCAM Sbjct: 120 LVNDKGEIVQKYRKILPWCPIECWYPGDKTYVVDGPKGLKVSLIICDDGNYPEIWRDCAM 179 Query: 181 KGAELVVRCQGYMYPAKEQQIMVSKAMAWMNNLYVAVANAAGFDGVYSYFGHSAIVGFDG 240 +GAEL+VRCQGYMYPAKEQQI + KAMAW N YVAVANA GFDGVYSYFGHS+I+GFDG Sbjct: 180 RGAELIVRCQGYMYPAKEQQIAIVKAMAWANQCYVAVANATGFDGVYSYFGHSSIIGFDG 239 Query: 241 RTLGECGTEEMGIQYAELSISAIRDARRNWQSQNHLYKLLHRGYTGKINSGESPAGVAEC 300 TLGECG EE G+QYA+LS+ IRDAR+ QSQN L+KLLHRGY+G SG+ GVAEC Sbjct: 240 HTLGECGEEENGLQYAQLSVQQIRDARKYDQSQNQLFKLLHRGYSGVFASGDGDKGVAEC 299 Query: 301 PFDFYRTWVNDPQAARAQVEALTRNSAGTPECPMPGIPIE 340 PF+FY+TWVNDP+ A+ VE +TR S G CP+ +P + Sbjct: 300 PFEFYKTWVNDPKKAQENVEKITRPSVGVAACPVGDLPTK 339 >jhp0279 [R] COG0388 Predicted amidohydrolase jHp Helicobacter pylori J99 Length = 339 Score = 539 bits (1388), Expect = e-153, Method: Compositional matrix adjust. Identities = 248/340 (72%), Positives = 288/340 (84%), Gaps = 1/340 (0%) Query: 1 MRHGDISSSKDAVGVAVVNYKMPRLHTRCEVLENAQKIAAMLVGMKQGLPGLDLVVFPEY 60 MRHGDISSS D VGVAVVNYKMPRLHT+ EVLEN + IA ++ G+KQGLPGLDL++FPEY Sbjct: 1 MRHGDISSSPDTVGVAVVNYKMPRLHTKNEVLENCRNIAKVIGGVKQGLPGLDLIIFPEY 60 Query: 61 STHGIMYDREEMFETAAAIPGDETRIFSEACRIAGVWGVFSLTGERHEEHPRKVPYNTLI 120 STHGIMYDR+EMF+TAA++PG+ET I +EAC+ VWGVFSLTGE+HE+ +K PYNTLI Sbjct: 61 STHGIMYDRQEMFDTAASVPGEETAILAEACKKNKVWGVFSLTGEKHEQ-AKKNPYNTLI 119 Query: 121 LINDQGEIVQKYRKIMPWTPIEGWYPGDATYVCDGPKGLKISLIICDDGNYPEIWRDCAM 180 L+ND+GEIVQKYRKI+PW PIE WYPGD TYV DGPKGLK+SLIICDDGNYPEIWRDCAM Sbjct: 120 LVNDKGEIVQKYRKILPWCPIECWYPGDKTYVVDGPKGLKVSLIICDDGNYPEIWRDCAM 179 Query: 181 KGAELVVRCQGYMYPAKEQQIMVSKAMAWMNNLYVAVANAAGFDGVYSYFGHSAIVGFDG 240 +GAEL+VRCQGYMYPAKEQQI + KAMAW N YVAVANA GFDGVYSYFGHS+I+GFDG Sbjct: 180 RGAELIVRCQGYMYPAKEQQIAIVKAMAWANQCYVAVANATGFDGVYSYFGHSSIIGFDG 239 Query: 241 RTLGECGTEEMGIQYAELSISAIRDARRNWQSQNHLYKLLHRGYTGKINSGESPAGVAEC 300 TLGECG EE G+QYA+LS+ IRDAR+ QSQN L+KLLHRGY+G SG+ GVAEC Sbjct: 240 HTLGECGEEENGLQYAQLSVQQIRDARKYDQSQNQLFKLLHRGYSGVFASGDGDKGVAEC 299 Query: 301 PFDFYRTWVNDPQAARAQVEALTRNSAGTPECPMPGIPIE 340 PF+FY+TWVNDP+ A+ VE TR S G CP+ +P + Sbjct: 300 PFEFYKTWVNDPKKAQENVEKFTRPSVGVAACPVGDLPTK 339 >HP1238 [R] COG0388 Predicted amidohydrolase Hpy Helicobacter pylori 26695 Length = 334 Score = 219 bits (558), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 116/296 (39%), Positives = 171/296 (57%), Gaps = 4/296 (1%) Query: 4 GDISSSKDAVGVAVVNYKMPRLHTRCEVLENAQKIAAMLVGMKQGLPGLDLVVFPEYSTH 63 G + + VA + + +P +++R ++ N + I L K G PG++L++FPEYST Sbjct: 5 GSMGKPIEGFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQ 64 Query: 64 GIMYDREEMFETAAAIPGDETRIFSEACRIAGVWGVFSLTGERHEEHPRKVPYNTLILIN 123 G+ + E +PG ET ++++AC+ A V+GVFS+ ER+ + K PYNT I+I+ Sbjct: 65 GLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIM-ERNPDS-NKNPYNTAIIID 122 Query: 124 DQGEIVQKYRKIMPWTPIEGWYPGDATY-VCDGPKGLKISLIICDDGNYPEIWRDCAMKG 182 QGEI+ KYRK+ PW PIE WYPGD VC+GP G K+++ IC DG PE+ R+ A KG Sbjct: 123 PQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKG 182 Query: 183 AELVVRCQGYMYPAKEQQIMVSKAMAWMNNLYVAVANAAGFDGVYSYFGHSAIVGFDGRT 242 + +R GY +Q I+ +++ AW N +Y N AG+D V+ YFG I FDG T Sbjct: 183 CNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTT 242 Query: 243 LGECGTEEMGIQYAELSISAIRDARRNWQSQNHLYKLLHRGYTGKINSGESPAGVA 298 L + I E+ +AR +W +N++Y L HRGY K GE AG+ Sbjct: 243 LVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAK-PGGEHDAGLT 297 >jhp1159 [R] COG0388 Predicted amidohydrolase jHp Helicobacter pylori J99 Length = 334 Score = 214 bits (544), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 113/296 (38%), Positives = 170/296 (57%), Gaps = 4/296 (1%) Query: 4 GDISSSKDAVGVAVVNYKMPRLHTRCEVLENAQKIAAMLVGMKQGLPGLDLVVFPEYSTH 63 G + + VA + + +P +++R ++ N + I L K G PG++L++FPEYST Sbjct: 5 GSMGKPIEGFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQ 64 Query: 64 GIMYDREEMFETAAAIPGDETRIFSEACRIAGVWGVFSLTGERHEEHPRKVPYNTLILIN 123 G+ + E +PG ET ++++AC+ A V+GV S+ ER+ + + PYNT I+I+ Sbjct: 65 GLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVLSIM-ERNPDS-NENPYNTAIIID 122 Query: 124 DQGEIVQKYRKIMPWTPIEGWYPGDATY-VCDGPKGLKISLIICDDGNYPEIWRDCAMKG 182 QG+I+ KYRK+ PW PIE WYPGD VC+GP G K+++ IC DG PE+ R+ A KG Sbjct: 123 PQGKIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKG 182 Query: 183 AELVVRCQGYMYPAKEQQIMVSKAMAWMNNLYVAVANAAGFDGVYSYFGHSAIVGFDGRT 242 + +R GY +Q I+ +++ AW N +Y N AG+D V+ YFG I FDG T Sbjct: 183 CNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTT 242 Query: 243 LGECGTEEMGIQYAELSISAIRDARRNWQSQNHLYKLLHRGYTGKINSGESPAGVA 298 L + I E+ +AR +W +N++Y L HRGY K GE AG+ Sbjct: 243 LVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAK-PGGEHDAGLT 297