BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0267.p (257 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB1521 [I] COG1562 Phytoene/squalene synthetase Nme Neisseria m... 268 9e-72 NMA1721 [I] COG1562 Phytoene/squalene synthetase NmA Neisseria m... 267 2e-71 alr1833 [I] COG1562 Phytoene/squalene synthetase Nos Nostoc sp. ... 110 4e-24 slr1255 [I] COG1562 Phytoene/squalene synthetase Syn Synechocystis 100 5e-21 NMA1339 [I] COG1562 Phytoene/squalene synthetase NmA Neisseria m... 91 3e-18 >NMB1521 [I] COG1562 Phytoene/squalene synthetase Nme Neisseria meningitidis MC58 Length = 275 Score = 268 bits (685), Expect = 9e-72, Method: Compositional matrix adjust. Identities = 140/268 (52%), Positives = 179/268 (66%), Gaps = 13/268 (4%) Query: 1 MAVDHYENFPVASLLLPARLRPAVADIYAFARSADDIADEGDAAPEERLAGLHAYEAQLD 60 M+V HYENFPV SL+LP RLR V +YAFAR+ADD+ADEG E RLAGL + +LD Sbjct: 6 MSVGHYENFPVGSLILPRRLRKPVHAVYAFARTADDMADEGSMPSEARLAGLEGLQRELD 65 Query: 61 LIARQQPCATPMFERLR-HTIARHELPLQPLRDLLSAFRQDVVTTRYEHYTDLLDYCRRS 119 ++A A P+ RL + L LQP DLLSAF QDVV TRY ++ +L DYCRRS Sbjct: 66 VLASGGRSAHPLIARLDAEAVVPFGLDLQPFYDLLSAFSQDVVKTRYGNFGELADYCRRS 125 Query: 120 ANPVGTLMLHLYGAX------------SALQLINFWQDIAIDWQKQRIYLPLEDLARFGV 167 ANPVG +ML LYG +ALQL+NFWQD+A+DWQK R+Y+P +DL +FGV Sbjct: 126 ANPVGRIMLALYGKTDAVCVAQSDGICTALQLVNFWQDVAVDWQKGRVYIPQDDLLKFGV 185 Query: 168 TPEDIAAGRCDGRWQQLMRFEVERARALMLAGAPLAKRLPGRIGWELRLVVQGGLRILTR 227 + E IAAGR D +Q+LM +E RA ++ AG+PLA+ L GRIG ELR++V G IL + Sbjct: 186 SEEQIAAGRADAAFQRLMAYECRRAFRMLKAGSPLARELNGRIGLELRMIVLGAQLILQK 245 Query: 228 IERVQGDVFGHRPKLGKADWLAVGWRAL 255 ++ + DVF RP L K DWL + +AL Sbjct: 246 LDACRYDVFAQRPVLDKKDWLIMLKKAL 273 >NMA1721 [I] COG1562 Phytoene/squalene synthetase NmA Neisseria meningitidis Z2491 Length = 276 Score = 267 bits (682), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 141/268 (52%), Positives = 177/268 (66%), Gaps = 13/268 (4%) Query: 1 MAVDHYENFPVASLLLPARLRPAVADIYAFARSADDIADEGDAAPEERLAGLHAYEAQLD 60 M+V HYENFPV SL+LP RLR V +YAFAR+ADD+ADEG E RLAGL A +LD Sbjct: 7 MSVGHYENFPVGSLILPRRLRKPVHAVYAFARTADDMADEGSMPSEARLAGLDALRRELD 66 Query: 61 LIARQQPCATPMFERLR-HTIARHELPLQPLRDLLSAFRQDVVTTRYEHYTDLLDYCRRS 119 ++A A P+ RL + L LQP DLLSAF QDVV TRY H+ +L DYCRRS Sbjct: 67 VLASGGRSAHPLIARLDAEAVVPFGLDLQPFYDLLSAFSQDVVKTRYAHFGELADYCRRS 126 Query: 120 ANPVGTLMLHLYGAX------------SALQLINFWQDIAIDWQKQRIYLPLEDLARFGV 167 ANPVG +ML LYG +ALQL+NFWQD+A+DWQK R+Y+P +DL +FGV Sbjct: 127 ANPVGRIMLALYGKTDAVCVAQSDGICTALQLVNFWQDVAVDWQKGRVYIPQDDLLKFGV 186 Query: 168 TPEDIAAGRCDGRWQQLMRFEVERARALMLAGAPLAKRLPGRIGWELRLVVQGGLRILTR 227 + IA GR D +Q+LM +E RA ++ AG+PLA+ L GRIG ELR++V G IL + Sbjct: 187 SEGQIAEGRADAAFQRLMAYECRRAFRMLKAGSPLARELKGRIGLELRMIVLGAQLILQK 246 Query: 228 IERVQGDVFGHRPKLGKADWLAVGWRAL 255 ++ + DVF RP L K DWL + RAL Sbjct: 247 LDACRYDVFAQRPVLDKKDWLIMLKRAL 274 >alr1833 [I] COG1562 Phytoene/squalene synthetase Nos Nostoc sp. PCC 7120 Length = 310 Score = 110 bits (274), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 85/280 (30%), Positives = 124/280 (44%), Gaps = 30/280 (10%) Query: 1 MAVDHYENFPVASLLLPARLRPAVADIYAFARSADDIADEGDAAPEERLAGLHAYEAQLD 60 + + + F + +LL+ R A+ IYA+ R D++ D G A+ L +E L+ Sbjct: 27 LTAKYAKTFYLGTLLMSPAKRQAIWAIYAWCRRTDELVD-GPASAITTPETLDLWEQHLE 85 Query: 61 LIARQQPCATPMFERLRHTIARHELPLQPLRDLLSAFRQDVVTTRYEHYTDLLDYCRRSA 120 + P L TI R L +QP RD+++ R D+ +RYE + +L YC R A Sbjct: 86 AMFAGHPKENYDVA-LVDTIQRFNLDIQPFRDMIAGQRMDLHRSRYETFEELYLYCYRVA 144 Query: 121 NPVG---TLMLHLYGAXS----------------------ALQLINFWQDIAIDWQKQRI 155 VG T ++ + + A QL N +D+ D ++ RI Sbjct: 145 GTVGLMSTAVMEVDNTTNTAPWHQSKPLYIPTQEAIALGIANQLTNILRDVGEDARRGRI 204 Query: 156 YLPLEDLARFGVTPEDIAAGRCDGRWQQLMRFEVERARALMLAGAPLAKRLPGRIGWELR 215 Y+PLEDLARF T +D G D RW+ LMRF++ERAR L W + Sbjct: 205 YIPLEDLARFNYTEQDFCNGVVDERWRSLMRFQIERARQFYAEAEKGITHLAPDARWPVW 264 Query: 216 LVVQGGLRILTRIERVQGDVFGHR---PKLGKADWLAVGW 252 +IL IER DVF R P+ K L + W Sbjct: 265 AASMLYGQILDVIERNDYDVFSQRAYVPQWKKLRTLPIAW 304 >slr1255 [I] COG1562 Phytoene/squalene synthetase Syn Synechocystis Length = 337 Score = 100 bits (248), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 123/279 (44%), Gaps = 29/279 (10%) Query: 1 MAVDHYENFPVASLLLPARLRPAVADIYAFARSADDIADEGDAAPEERLAGLHAYEAQLD 60 + + + F + +LL+P R A+ IY + R D++ D G A L +E +L+ Sbjct: 55 VTAQYAKTFYLGTLLMPPAKRRAIWAIYLWCRRTDELVD-GPQAATTTPETLDHWERRLE 113 Query: 61 LIARQQPCATPMFERLRHTIARHELPLQPLRDLLSAFRQDVVTTRYEHYTDLLDYCRRSA 120 I QP L T+ L +QP RD+++ R D+ +RY+ + +L YC R A Sbjct: 114 GIFAGQPQDDADVA-LVDTLETFPLDIQPFRDMIAGQRMDLYRSRYQTFEELDLYCYRVA 172 Query: 121 NPVGTLMLHLYGAXS------------------------ALQLINFWQDIAIDWQKQRIY 156 VG + + G + A QL N +D+ D ++ RIY Sbjct: 173 GTVGLMSSAVLGVDTGNGQAPWQPDAVYIPQEEAIALGVANQLTNILRDVGEDVERGRIY 232 Query: 157 LPLEDLARFGVTPEDIAAGRCDGRWQQLMRFEVERARALMLAGAPLAKRLPGRIGWELRL 216 LPLEDL RF + +D+ G D RW+ LM+FE++RAR + L W + Sbjct: 233 LPLEDLERFNYSEQDLLNGVNDDRWRSLMKFEIDRARHYFEDAERGIRALNRDARWPVWT 292 Query: 217 VVQGGLRILTRIERVQGDVFGHR---PKLGKADWLAVGW 252 + IL IE +VF R P K +L V W Sbjct: 293 ALMLYKGILDVIEANNYNVFNRRAYVPTPKKLLYLPVAW 331 >NMA1339 [I] COG1562 Phytoene/squalene synthetase NmA Neisseria meningitidis Z2491 Length = 290 Score = 90.5 bits (223), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 61/191 (31%), Positives = 91/191 (47%), Gaps = 13/191 (6%) Query: 15 LLPARLRPAVADIYAFARSADDIADEGDAAPEERLAGLHAYEAQLDLIARQQPCATPMFE 74 L R AV +YAF R DD+ DE + P+ A L+ + LD + P+ + Sbjct: 24 FLTQEKRDAVTVLYAFCRELDDVVDEC-SNPDVAQATLNWWRGDLDKVFGGAMPEHPVNQ 82 Query: 75 RLRHTIARHELPLQPLRDLLSAFRQDVVTTRYEHYTDLLDYCRRSANPVGTLMLHLYGAX 134 LR +LP L L+ + D++ RY + +L YCRR A VG L+ + G Sbjct: 83 ALRQVKETFKLPKYELEALIDGMQMDLLRVRYGSFEELKLYCRRVAGVVGCLIARILGFS 142 Query: 135 S------------ALQLINFWQDIAIDWQKQRIYLPLEDLARFGVTPEDIAAGRCDGRWQ 182 ALQL N +D+ D ++ RIYLP+E++ RF V I G + Sbjct: 143 DDQTLEYADKMGLALQLTNIIRDVGEDARRGRIYLPMEEMRRFDVPASVILQCSPTGNFA 202 Query: 183 QLMRFEVERAR 193 +LM F+++RAR Sbjct: 203 ELMAFQIKRAR 213