BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0265.p (249 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc3699 [IQR] COG1028 Dehydrogenases with different specificitie... 356 2e-98 mlr3115 [IQR] COG1028 Dehydrogenases with different specificitie... 252 5e-67 SMc00372 [IQR] COG1028 Dehydrogenases with different specificiti... 251 1e-66 MA0415 [IQR] COG1028 Dehydrogenases with different specificities... 167 2e-41 BS_gdh [IQR] COG1028 Dehydrogenases with different specificities... 154 1e-37 >AGc3699 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 249 Score = 356 bits (914), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 182/249 (73%), Positives = 204/249 (81%) Query: 1 MNTLQGKVALITGASAGIGRATALLFARHGAALILTARRQDALEQVAALIRAQGGRASVV 60 M L+ KVA+ITGAS+GIGRATA+LF GAA+++ AR + AL++VAA IR GGR V Sbjct: 1 MKLLENKVAIITGASSGIGRATAMLFVTQGAAVVINARGEKALQEVAADIRDAGGRVHAV 60 Query: 61 AGDVGEAATHERGVAMALDEFGGLDIAINNAGAVGACKPLAEISPQQWQDTLHANLTSAF 120 AGD G A TH R A+ FGGLDIAINNAGAVGA KPLAEISP++W L+ NLTSAF Sbjct: 61 AGDAGVAETHSRLADAAVGVFGGLDIAINNAGAVGAMKPLAEISPEEWDHVLNVNLTSAF 120 Query: 121 LGARCQIPAMLARGAGAIVFTSSFVGSSAGLPGMAAYGAAKAGLMGLVKGIAADYAVQGI 180 LGAR QIP ML RG G+IVFTSSFVG+SAG+PGM+AYG AKA LMGLVKGI ADYA+ GI Sbjct: 121 LGARYQIPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTAKAALMGLVKGITADYAINGI 180 Query: 181 RANALLPGGVDTDMGGDPQQKQWAAGLHAMKRIAQPEEIAAAALFLASPMASFVTGTALY 240 RANALLPGGVDT GDP QK+WAAGLHAMKRIAQPEEIA AALFLASPMASFV G AL+ Sbjct: 181 RANALLPGGVDTPAAGDPAQKEWAAGLHAMKRIAQPEEIAQAALFLASPMASFVAGAALF 240 Query: 241 ADGGNSAVK 249 ADGGN+AVK Sbjct: 241 ADGGNAAVK 249 >mlr3115 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 259 Score = 252 bits (644), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 134/254 (52%), Positives = 181/254 (71%), Gaps = 10/254 (3%) Query: 1 MNTLQGKVALITGASAGIGRATALLFARHGAALILTARRQDALEQVAALIRAQGGRASVV 60 M L K+A++TGAS+GIGRATA LFA GA +++ ARRQ L+ + A I G A + Sbjct: 4 MLALANKIAIVTGASSGIGRATAKLFAEEGARVVVAARRQAELDTLVAEISDAEGTAVAL 63 Query: 61 AGDVGEAATHERGVAMALDEFGGLDIAINNAGAVGACKPLAEISPQQWQDTLHANLTSAF 120 AGDV + A + V +A++ FGGLD+A NNAGAVG P++ +S + W++TL NLTSAF Sbjct: 64 AGDVRDEAYAKALVDLAVESFGGLDVAFNNAGAVGQMGPISGLSLEGWRETLDTNLTSAF 123 Query: 121 LGARCQIPAMLARGAGAIVFTSSFVGSSAGLPGMAAYGAAKAGLMGLVKGIAADYAVQGI 180 LGA+ Q+PAM+ RG G+++FTS+FVG + G+PGM +Y A+KAGL+GL + +AA++ QG+ Sbjct: 124 LGAKYQVPAMIERGGGSLIFTSTFVGHTIGMPGMTSYAASKAGLIGLTQVLAAEHGPQGV 183 Query: 181 RANALLPGGVDT--------DMGGDPQQKQWAAGLHAMKRIAQPEEIAAAALFLASPMAS 232 R NALLPGG DT D G P+ + LHA+KR+AQPEEIA +AL+LAS +S Sbjct: 184 RVNALLPGGTDTPASITNAPDAG--PEVLAFVQALHALKRMAQPEEIARSALYLASDASS 241 Query: 233 FVTGTALYADGGNS 246 F TGTAL+ADGG S Sbjct: 242 FTTGTALFADGGVS 255 >SMc00372 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 256 Score = 251 bits (641), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 140/255 (54%), Positives = 183/255 (71%), Gaps = 6/255 (2%) Query: 1 MNTLQGKVALITGASAGIGRATALLFARHGAALILTARRQDALEQVAALIRAQGGRASVV 60 M+ L+GK+A++TGAS+GIGRA ALLFAR GA +++TAR +AL ++ I GG A+ + Sbjct: 1 MSRLEGKIAIVTGASSGIGRAAALLFAREGAKVVVTARNGNALAELTDEIAGGGGEAAAL 60 Query: 61 AGDVGEAATHERGVAMALDEFGGLDIAINNAGAVGACKPLAEISPQQWQDTLHANLTSAF 120 AGDVG+ A HE V +A+ FGGLD A NNAGA+GA ++ +S + W++TL NLTSAF Sbjct: 61 AGDVGDEALHEALVELAVRRFGGLDTAFNNAGALGAMGEISSLSVEGWRETLDTNLTSAF 120 Query: 121 LGARCQIPAMLARGAGAIVFTSSFVGSSAGLPGMAAYGAAKAGLMGLVKGIAADYAVQGI 180 L A+ Q+PA+ A G G++ FTSSFVG +AG G+A Y A+KAGL+GLV+ +A + +GI Sbjct: 121 LAAKYQVPAIAALGGGSLTFTSSFVGHTAGFAGVAPYAASKAGLIGLVQALAVELGARGI 180 Query: 181 RANALLPGGVDTDM------GGDPQQKQWAAGLHAMKRIAQPEEIAAAALFLASPMASFV 234 R NALLPGG DT G P+ + + GLHA+KRIA+PEEIA AAL+LAS ASFV Sbjct: 181 RVNALLPGGTDTPANFANLPGAAPETRGFVEGLHALKRIARPEEIAEAALYLASDGASFV 240 Query: 235 TGTALYADGGNSAVK 249 TG AL ADGG S K Sbjct: 241 TGAALLADGGASVTK 255 >MA0415 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mac Methanosarcina acetivorans str.C2A Length = 256 Score = 167 bits (424), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 105/247 (42%), Positives = 135/247 (54%), Gaps = 7/247 (2%) Query: 6 GKVALITGASAGIGRATALLFARHGAALILTARRQDALEQVAALIRAQGGRASVVAGDVG 65 GKVA +TG + GIG+ATA+ FAR GA + LT Q A EQ I GG+A + DV Sbjct: 11 GKVAFVTGGATGIGQATAVAFAREGANVALTYHNQGA-EQTVRRIEELGGQALAIKCDVI 69 Query: 66 EAATHERGVAMALDEFGGLDIAINNAGAVGACKPLAEISPQQWQDTLHANLTSAFLGARC 125 + + + FG LD A NNAG G AE ++W + NLT FL + Sbjct: 70 REEDVKNAIEKIIQTFGQLDYAFNNAGIEGKTVITAEYPVEEWNRVIATNLTGVFLCMKY 129 Query: 126 QIPAMLARGAGAIVFTSSFVGSSAGLPGMAAYGAAKAGLMGLVKGIAADYAVQGIRANAL 185 +IP ML +GAGAIV SS G + G P ++ Y A+K G++GL K A DYA IR NA+ Sbjct: 130 EIPQMLKQGAGAIVNCSSGAGLT-GFPDISPYVASKHGVVGLTKTAALDYAKSNIRINAV 188 Query: 186 LPGGVDTDM-----GGDPQQKQWAAGLHAMKRIAQPEEIAAAALFLASPMASFVTGTALY 240 PG DT M GG P+ + + R+ +PEEIA A L+L S ASFVTG + Sbjct: 189 CPGMTDTPMMERYSGGTPEGYEKIIEQEPIGRMGRPEEIAIAVLWLCSDAASFVTGDVMR 248 Query: 241 ADGGNSA 247 DGG A Sbjct: 249 VDGGQLA 255 >BS_gdh [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bsu Bacillus subtilis Length = 261 Score = 154 bits (390), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 96/247 (38%), Positives = 135/247 (54%), Gaps = 8/247 (3%) Query: 4 LQGKVALITGASAGIGRATALLFARHGAALILT--ARRQDALEQVAALIRAQGGRASVVA 61 L+GKV ITGA++G+G+A A+ F + A +++ + +QD E +I+A GG A VV Sbjct: 5 LKGKVVAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKEEVIKA-GGEAVVVQ 63 Query: 62 GDVGEAATHERGVAMALDEFGGLDIAINNAGAVGACKPLAEISPQQWQDTLHANLTSAFL 121 GDV + + V A+ EFG LDI INNAG P E+ + W + NLT AFL Sbjct: 64 GDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPV-PSHEMPLKDWDKVIGTNLTGAFL 122 Query: 122 GARCQIPAMLARGAGAIVFTSSFVGSSAGLPGMAAYGAAKAGLMGLVKGIAADYAVQGIR 181 G+R I + V S V P Y A+K G+ + + +A +YA +GIR Sbjct: 123 GSREAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYAPKGIR 182 Query: 182 ANALLPGGVDTDMG----GDPQQKQWAAGLHAMKRIAQPEEIAAAALFLASPMASFVTGT 237 N + PG ++T + DP+QK + M I +PEEIAA A +LAS AS+VTG Sbjct: 183 VNNIGPGAINTPINAEKFADPKQKADVESMIPMGYIGEPEEIAAVAAWLASKEASYVTGI 242 Query: 238 ALYADGG 244 L+ADGG Sbjct: 243 TLFADGG 249