BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0184.p (468 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4024 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Pae... 705 0.0 RSc3127 Non COG 671 0.0 lin1139 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Li... 481 e-135 FN0079 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Fnu... 477 e-134 STM2458 [E] COG4303 Ethanolamine ammonia-lyase, large subunit St... 461 e-129 >PA4024 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Pae Pseudomonas aeruginosa Length = 464 Score = 705 bits (1820), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/463 (73%), Positives = 389/463 (84%), Gaps = 2/463 (0%) Query: 5 RFRHSVGSASYVFRDLKELMAKASPARSGDLLAGVAAGSAEERAIAQMALAALPLKTFLE 64 RF HSVG +Y F LK++MAKASPARSGD LAGVAA + ER AQMALA +PLK FL+ Sbjct: 3 RFTHSVGGETYRFDSLKDVMAKASPARSGDFLAGVAASNDGERVAAQMALADIPLKHFLD 62 Query: 65 EPLIPYEEDEVTRLILDSHDRAAFATIAHLTVGDFRNWLLADDTDSAVLAAVAPGITPEM 124 E LIPYE+DEVTRLI+D+H R AFA ++HLTVG FR+WLL D D A L A+APG+TPEM Sbjct: 63 EALIPYEDDEVTRLIIDTHQRDAFAPVSHLTVGGFRDWLLGDAADEASLRALAPGLTPEM 122 Query: 125 AAAVSKIMRNQDLILVAKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASMLDGL 184 AAAVSKIMR QDL+LVA+K RVVT FRNT+GL GRLSTRLQPNHPTDD +GIAAS+LDGL Sbjct: 123 AAAVSKIMRVQDLVLVAQKIRVVTRFRNTLGLRGRLSTRLQPNHPTDDPAGIAASILDGL 182 Query: 185 LYGNGDAVIGINPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPV 244 L+GNGDA++GINPATD++ + L+ M+ +I RYEIPTQ+CVLTHVT++I AI RG P+ Sbjct: 183 LFGNGDAMLGINPATDSMASICALLEMLDAIIQRYEIPTQACVLTHVTSSIEAINRGVPL 242 Query: 245 DLVFQSIAGTEAANRGFGIDLALLGEAREAALSLQRGTVGDNVMYFETGQGSALSANAHH 304 DLVFQSIAGTEAAN FGI L +L E EA LS +RGT+G+N+MYFETGQGSALSANAHH Sbjct: 243 DLVFQSIAGTEAANASFGISLKILQEGYEAGLSQKRGTLGNNLMYFETGQGSALSANAHH 302 Query: 305 GIDQQTCEARAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMG 364 G+DQQTCE RAYAVAR FKP LVNTVVGFIGPEYLY+GKQIIRAGLEDHFC KLLG+PMG Sbjct: 303 GVDQQTCETRAYAVARHFKPFLVNTVVGFIGPEYLYNGKQIIRAGLEDHFCGKLLGVPMG 362 Query: 365 CDVCYTNHAEADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLG 424 CD+CYTNHAEADQ+DMD+LLTLLGVAG F+MGIPGSDD+MLNYQTTSFHDALYAR+ LG Sbjct: 363 CDICYTNHAEADQDDMDMLLTLLGVAGINFIMGIPGSDDVMLNYQTTSFHDALYARQTLG 422 Query: 425 SRPAPEFEDWLHRMQIFNPGGEDQAFRLHADMPPGFRETLLRL 467 +PAPEFEDWL RM IF D R ++PP FR+ L +L Sbjct: 423 LKPAPEFEDWLQRMGIFTQA--DGRIRFGDELPPAFRQALAQL 463 >RSc3127 Non COG Length = 464 Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/463 (73%), Positives = 392/463 (84%), Gaps = 2/463 (0%) Query: 5 RFRHSVGSASYVFRDLKELMAKASPARSGDLLAGVAAGSAEERAIAQMALAALPLKTFLE 64 RF H++G +Y F +L++++AKASPARSGD LAG+AA SA ER AQMALA +PL+ FL+ Sbjct: 3 RFSHTLGHETYRFDNLRDVLAKASPARSGDALAGIAAASAAERVAAQMALAEIPLRHFLD 62 Query: 65 EPLIPYEEDEVTRLILDSHDRAAFATIAHLTVGDFRNWLLADDTDSAVLAAVAPGITPEM 124 E +IPYE DEVTRLI+D+HD AAFA ++HLTVGDFR+WLL D D A LAA+APG+TPEM Sbjct: 63 EAVIPYEADEVTRLIVDTHDAAAFAPVSHLTVGDFRDWLLGDAADEAALAALAPGLTPEM 122 Query: 125 AAAVSKIMRNQDLILVAKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASMLDGL 184 AAAVSK+MR QDLILVA+K RVVT FRNTIGL GR++TRLQPNHPTDD +GIAAS+LDGL Sbjct: 123 AAAVSKLMRVQDLILVAQKTRVVTRFRNTIGLRGRMATRLQPNHPTDDPAGIAASLLDGL 182 Query: 185 LYGNGDAVIGINPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPV 244 +YG+GDAVIG+NP +D+ + L+GM+ VI RY+IPTQ+CVLTHVT T+ AI RG PV Sbjct: 183 MYGSGDAVIGVNPVSDSTAAICDLLGMLDAVIRRYDIPTQACVLTHVTTTLEAIRRGMPV 242 Query: 245 DLVFQSIAGTEAANRGFGIDLALLGEAREAALSLQRGTVGDNVMYFETGQGSALSANAHH 304 DLVFQSIAGTEAAN FG+ LALL EAR+AAL LQRGTVGDNVMYFETGQGSALSANAHH Sbjct: 243 DLVFQSIAGTEAANASFGVSLALLHEARDAALGLQRGTVGDNVMYFETGQGSALSANAHH 302 Query: 305 GIDQQTCEARAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMG 364 G+DQQTCEARAYAVAR F+PLLVNTVVGFIGPEYLYDGKQI+RAGLEDHFC KLLG+PMG Sbjct: 303 GVDQQTCEARAYAVARRFRPLLVNTVVGFIGPEYLYDGKQILRAGLEDHFCGKLLGVPMG 362 Query: 365 CDVCYTNHAEADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLG 424 CD+CYTNHAEADQ+DMD LLTLLG AG ++MGIPGSDD+MLNYQTTSFHDALY RRVLG Sbjct: 363 CDICYTNHAEADQDDMDTLLTLLGAAGVNYIMGIPGSDDVMLNYQTTSFHDALYVRRVLG 422 Query: 425 SRPAPEFEDWLHRMQIFNPGGEDQAFRLHADMPPGFRETLLRL 467 RPAPEFEDWL RM I G D L +P FR + +L Sbjct: 423 LRPAPEFEDWLARMGICTAG--DGRIALADGLPDPFRRAVAQL 463 >lin1139 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Lin Listeria innocua Length = 454 Score = 481 bits (1238), Expect = e-135, Method: Compositional matrix adjust. Identities = 231/426 (54%), Positives = 295/426 (69%), Gaps = 3/426 (0%) Query: 14 SYVFRDLKELMAKASPARSGDLLAGVAAGSAEERAIAQMALAALPLKTFLEEPLIPYEED 73 +Y F+ + +++AKA+ +SGD LAGVAA SAEER A++ L+ + L P++PYE D Sbjct: 11 TYQFKSITDVLAKANEEKSGDRLAGVAAESAEERVAAKVVLSKMTLGDLRNNPVVPYETD 70 Query: 74 EVTRLILDSHDRAAFATIAHLTVGDFRNWLLADDTDSAVLAAVAPGITPEMAAAVSKIMR 133 EVTR+I D + +I + TV + R W+L T A + VA G+T E+ AAV+K+M Sbjct: 71 EVTRIIQDQVNERIHDSIKNWTVEELREWILDHKTTDADIKRVARGLTSEIIAAVTKLMS 130 Query: 134 NQDLILVAKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASMLDGLLYGNGDAVI 193 N DLI AKK RV+ TIGLPG S RLQPNHPTDD GI AS+++GL YG GDAVI Sbjct: 131 NLDLIYGAKKIRVIAHANTTIGLPGTFSARLQPNHPTDDPDGILASLMEGLTYGIGDAVI 190 Query: 194 GINPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPVDLVFQSIAG 253 G+NP D+ VV+L+ + +++++PTQ+CVL HV + A+ RGAP LVFQSIAG Sbjct: 191 GLNPVDDSTDSVVRLLNKFEEFRSKWDVPTQTCVLAHVKTQMEAMRRGAPTGLVFQSIAG 250 Query: 254 TEAANRGFGIDLALLGEAREAALSLQRG-TVGDNVMYFETGQGSALSANAHHGIDQQTCE 312 +E N FG D A + EAR+ L+LQ G G NVMYFETGQGS LS++AH G+DQ T E Sbjct: 251 SEKGNTAFGFDGATIEEARQ--LALQSGAATGPNVMYFETGQGSELSSDAHFGVDQVTME 308 Query: 313 ARAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMGCDVCYTNH 372 AR Y A+ F P LVNTVVGFIGPEYLYD KQ+IRAGLEDHF KL G+ MGCDVCYTNH Sbjct: 309 ARCYGFAKKFDPFLVNTVVGFIGPEYLYDSKQVIRAGLEDHFMGKLTGISMGCDVCYTNH 368 Query: 373 AEADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLGSRPAPEFE 432 +ADQND++ L LL AGC F+MGIP DD+MLNYQTT +H+ R + G +P EF+ Sbjct: 369 MKADQNDVENLSVLLTAAGCNFIMGIPHGDDVMLNYQTTGYHETATLRELFGLKPIKEFD 428 Query: 433 DWLHRM 438 W+ +M Sbjct: 429 QWMEKM 434 >FN0079 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Fnu Fusobacterium nucleatum Length = 455 Score = 477 bits (1227), Expect = e-134, Method: Compositional matrix adjust. Identities = 232/433 (53%), Positives = 297/433 (68%), Gaps = 3/433 (0%) Query: 15 YVFRDLKELMAKASPARSGDLLAGVAAGSAEERAIAQMALAALPLKTFLEEPLIPYEEDE 74 Y F LKE+MAKA+ +SGD LAG+AA S++ER A++ L+ + LK E P +PYEEDE Sbjct: 12 YNFSSLKEVMAKANEKKSGDTLAGIAASSSKERVAAKVVLSKITLKDLKENPAVPYEEDE 71 Query: 75 VTRLILDSHDRAAFATIAHLTVGDFRNWLLADDTDSAVLAAVAPGITPEMAAAVSKIMRN 134 VTR+I+D + + I TV D R WLL+++ + + + G+T EM AAV+K+M N Sbjct: 72 VTRIIIDDLNLQIYDEIKDWTVSDLREWLLSEEATPSKINWIRRGLTSEMIAAVAKLMSN 131 Query: 135 QDLILVAKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASMLDGLLYGNGDAVIG 194 DLI+ AKK V TIG L+ RLQPNH TDD GI S L+GL YG GDAVIG Sbjct: 132 MDLIVAAKKIEVRAHCNTTIGGYDTLAVRLQPNHTTDDPDGIMISTLEGLSYGIGDAVIG 191 Query: 195 INPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPVDLVFQSIAGT 254 +NP D+V V+ ++ + Y+IPTQ+CVL HVT + AI+RGA VD++FQSIAG+ Sbjct: 192 LNPVDDSVDSVMAVMERFHKIKTEYQIPTQTCVLAHVTTQMEAIKRGAKVDMIFQSIAGS 251 Query: 255 EAANRGFGIDLALLGEAREAALSLQRGT-VGDNVMYFETGQGSALSANAHHGIDQQTCEA 313 E N FGI A++ EAR+ L L+ GT G N+MYFETGQGS LS++AH+G DQ T EA Sbjct: 252 EKGNEAFGITGAMIEEARQ--LGLKYGTAAGPNIMYFETGQGSELSSDAHNGADQVTMEA 309 Query: 314 RAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMGCDVCYTNHA 373 R Y A+ F+P LVNTVVGFIGPEYLYD KQ+IRAGLEDHF KL GLPMG DVCYTNH Sbjct: 310 RCYGFAKRFQPFLVNTVVGFIGPEYLYDSKQVIRAGLEDHFMGKLHGLPMGVDVCYTNHM 369 Query: 374 EADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLGSRPAPEFED 433 +A+Q+D+++L TLL AGC + MG+P DDIMLNYQTT FHD R + G +P EF++ Sbjct: 370 KAEQSDVEILATLLTAAGCNYFMGVPAGDDIMLNYQTTGFHDNQSLRELFGKQPIKEFKE 429 Query: 434 WLHRMQIFNPGGE 446 WL + G+ Sbjct: 430 WLVKYGFMTEDGK 442 >STM2458 [E] COG4303 Ethanolamine ammonia-lyase, large subunit Sty Salmonella typhimurium LT2 Length = 453 Score = 461 bits (1185), Expect = e-129, Method: Compositional matrix adjust. Identities = 226/440 (51%), Positives = 295/440 (67%), Gaps = 1/440 (0%) Query: 5 RFRHSVGSASYVFRDLKELMAKASPARSGDLLAGVAAGSAEERAIAQMALAALPLKTFLE 64 + + ++ Y F+D+KE++AKA+ RSGD+LAGVAA S++ER A+ L+ + + Sbjct: 2 KLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRN 61 Query: 65 EPLIPYEEDEVTRLILDSHDRAAFATIAHLTVGDFRNWLLADDTDSAVLAAVAPGITPEM 124 P+I YEED VTRLI D + A+ I + ++ + R ++L+D+T +A G+T E+ Sbjct: 62 NPVIAYEEDCVTRLIQDDVNETAYNRIKNWSISELREYVLSDETSVDDIAFTRKGLTSEV 121 Query: 125 AAAVSKIMRNQDLILVAKKCRVVTAFRNTIGLPGRLSTRLQPNHPTDDASGIAASMLDGL 184 AAV+KI N DLI KK V+ TIG+PG S RLQPN DD IAA + +GL Sbjct: 122 VAAVAKICSNADLIYGGKKMPVIKKANTTIGIPGTFSCRLQPNDTRDDVQSIAAQIYEGL 181 Query: 185 LYGNGDAVIGINPATDNVPQVVKLVGMMADVIARYEIPTQSCVLTHVTNTIAAIERGAPV 244 +G GDAVIG+NP TD+V + +++ + VI ++ IPTQ CVL HVT I AI RGAP Sbjct: 182 SFGAGDAVIGVNPVTDDVENLTRVLDTVYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPG 241 Query: 245 DLVFQSIAGTEAANRGFGIDLALLGEAREAALSLQRGTVGDNVMYFETGQGSALSANAHH 304 L+FQSI G+E + FG++LA+L EAR R G+N +YFETGQGSALSA A+ Sbjct: 242 GLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNR-IAGENCLYFETGQGSALSAGANF 300 Query: 305 GIDQQTCEARAYAVARAFKPLLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCAKLLGLPMG 364 G DQ T EAR Y +AR + P LVNTVVGFIGPEYLY+ +QIIRAGLEDHF KL G+ MG Sbjct: 301 GADQVTMEARNYGLARHYDPFLVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMG 360 Query: 365 CDVCYTNHAEADQNDMDVLLTLLGVAGCTFVMGIPGSDDIMLNYQTTSFHDALYARRVLG 424 CD CYTNHA+ADQN + L+ LL AGC ++MG+P DDIMLNYQTT+FHD R++L Sbjct: 361 CDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLN 420 Query: 425 SRPAPEFEDWLHRMQIFNPG 444 RP+PEFE WL M I G Sbjct: 421 LRPSPEFERWLETMGIMANG 440