BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0182.p (742 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Rv0066c [C] COG2838 Monomeric isocitrate dehydrogenase Mtu Mycob... 1162 0.0 MT0072 [C] COG2838 Monomeric isocitrate dehydrogenase MtC Mycoba... 1162 0.0 ML2672 [C] COG2838 Monomeric isocitrate dehydrogenase Mle Mycoba... 1133 0.0 PA2624 [C] COG2838 Monomeric isocitrate dehydrogenase Pae Pseudo... 1066 0.0 VC1141 [C] COG2838 Monomeric isocitrate dehydrogenase Vch Vibrio... 970 0.0 >Rv0066c [C] COG2838 Monomeric isocitrate dehydrogenase Mtu Mycobacterium tuberculosis H37Rv Length = 745 Score = 1162 bits (3007), Expect = 0.0, Method: Compositional matrix adjust. Identities = 547/739 (74%), Positives = 630/739 (85%), Gaps = 1/739 (0%) Query: 5 NPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTDEQKV 64 PTIIYTLTDEAP LAT++ LPIV+ F AGI + SDISVAARILAEFP+YLT+EQ+V Sbjct: 5 QPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTEEQRV 64 Query: 65 PDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEEEKAL 124 PDNLA LG LTQ PD NIIKLPNISAS+ QL AAI+ELQ +GY +PDYP +P T++EKA+ Sbjct: 65 PDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQEKAI 124 Query: 125 QKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHGGDFY 184 ++RYA+ GSAVNPVLR+GNSDRRAP AVK YARKHPHSM +WSMASRTHVAHM GDFY Sbjct: 125 KERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRHGDFY 184 Query: 185 AGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEEQMQD 244 AGEKS+TLD+A +V+M+L+ KSG+TIVLKP++ L G++IDSMFMSKKALC +YEEQMQD Sbjct: 185 AGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEEQMQD 244 Query: 245 AFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMSGVYE 304 AFET ++ S+HVKATMMKVSHPIVFGHAVR +YKD F KH +LF ++GVN NNG+S +Y Sbjct: 245 AFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLSDLYS 304 Query: 305 KINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIRAGGK 364 KI +LP +++ E++ DL RP LAMVDSA+GI+N H+P+DVIVDASMPAMIRAGGK Sbjct: 305 KIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIRAGGK 364 Query: 365 MWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAEEYGS 424 M+ A GK +DTKA+ PESTF+RIYQE+INFCKTNG FDPTTMGTVPNVGLMAQ+AEEYGS Sbjct: 365 MYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAEEYGS 424 Query: 425 HDKTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRARLSG 483 HDKTFEI + GVA IV + G+VLL +NVE GDIWRMC VKDA +RDWVKLAVTRAR+SG Sbjct: 425 HDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRARISG 484 Query: 484 MPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDTISV 543 MP +FWLDPYRPHE ELIKKV TYLKDHD G DIQIMSQVR+MRYT ER++RGLDTI+ Sbjct: 485 MPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLDTIAA 544 Query: 544 TGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENHLRW 603 TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGM+ETGAGGSAPKHV+QLV ENHLRW Sbjct: 545 TGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRW 604 Query: 604 DSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNRGSHF 663 DSLGEFLAL E++GIKTGN RAK+L KTLDAA GKLLDN+KSPS KTGELDNRGS F Sbjct: 605 DSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNRGSQF 664 Query: 664 YLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLPDRE 723 YLA+YWAQELAAQ DD +LA+ FA LA L +NE IV EL VQG+ VDIGGYY PD + Sbjct: 665 YLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYAPDSD 724 Query: 724 KTFAVMRPSTTLNQALETL 742 T AVMRPS T N ALE + Sbjct: 725 MTTAVMRPSKTFNAALEAV 743 >MT0072 [C] COG2838 Monomeric isocitrate dehydrogenase MtC Mycobacterium tuberculosis CDC1551 Length = 745 Score = 1162 bits (3007), Expect = 0.0, Method: Compositional matrix adjust. Identities = 547/739 (74%), Positives = 630/739 (85%), Gaps = 1/739 (0%) Query: 5 NPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTDEQKV 64 PTIIYTLTDEAP LAT++ LPIV+ F AGI + SDISVAARILAEFP+YLT+EQ+V Sbjct: 5 QPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTEEQRV 64 Query: 65 PDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEEEKAL 124 PDNLA LG LTQ PD NIIKLPNISAS+ QL AAI+ELQ +GY +PDYP +P T++EKA+ Sbjct: 65 PDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQEKAI 124 Query: 125 QKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHGGDFY 184 ++RYA+ GSAVNPVLR+GNSDRRAP AVK YARKHPHSM +WSMASRTHVAHM GDFY Sbjct: 125 KERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRHGDFY 184 Query: 185 AGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEEQMQD 244 AGEKS+TLD+A +V+M+L+ KSG+TIVLKP++ L G++IDSMFMSKKALC +YEEQMQD Sbjct: 185 AGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEEQMQD 244 Query: 245 AFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMSGVYE 304 AFET ++ S+HVKATMMKVSHPIVFGHAVR +YKD F KH +LF ++GVN NNG+S +Y Sbjct: 245 AFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLSDLYS 304 Query: 305 KINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIRAGGK 364 KI +LP +++ E++ DL RP LAMVDSA+GI+N H+P+DVIVDASMPAMIRAGGK Sbjct: 305 KIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIRAGGK 364 Query: 365 MWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAEEYGS 424 M+ A GK +DTKA+ PESTF+RIYQE+INFCKTNG FDPTTMGTVPNVGLMAQ+AEEYGS Sbjct: 365 MYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAEEYGS 424 Query: 425 HDKTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRARLSG 483 HDKTFEI + GVA IV + G+VLL +NVE GDIWRMC VKDA +RDWVKLAVTRAR+SG Sbjct: 425 HDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRARISG 484 Query: 484 MPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDTISV 543 MP +FWLDPYRPHE ELIKKV TYLKDHD G DIQIMSQVR+MRYT ER++RGLDTI+ Sbjct: 485 MPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLDTIAA 544 Query: 544 TGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENHLRW 603 TGNILRDYLTDLFPI+ELGTSAKMLS+VPLMAGGGM+ETGAGGSAPKHV+QLV ENHLRW Sbjct: 545 TGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRW 604 Query: 604 DSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNRGSHF 663 DSLGEFLAL E++GIKTGN RAK+L KTLDAA GKLLDN+KSPS KTGELDNRGS F Sbjct: 605 DSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNRGSQF 664 Query: 664 YLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLPDRE 723 YLA+YWAQELAAQ DD +LA+ FA LA L +NE IV EL VQG+ VDIGGYY PD + Sbjct: 665 YLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYAPDSD 724 Query: 724 KTFAVMRPSTTLNQALETL 742 T AVMRPS T N ALE + Sbjct: 725 MTTAVMRPSKTFNAALEAV 743 >ML2672 [C] COG2838 Monomeric isocitrate dehydrogenase Mle Mycobacterium leprae Length = 746 Score = 1133 bits (2930), Expect = 0.0, Method: Compositional matrix adjust. Identities = 540/731 (73%), Positives = 616/731 (84%), Gaps = 1/731 (0%) Query: 7 TIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTDEQKVPD 66 TIIYTLTDEAP LAT++ LPIV+ FT AGI V SDISVAARILAEFP+YLT+EQ+VP+ Sbjct: 7 TIIYTLTDEAPLLATYAFLPIVRAFTKPAGIKVQTSDISVAARILAEFPDYLTEEQRVPN 66 Query: 67 NLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEEEKALQK 126 NLA LG LTQ PD NIIKLPNISAS+ QL AAI+ELQ++G+KLPDYP++P + +E ++ Sbjct: 67 NLAELGRLTQLPDTNIIKLPNISASVPQLMAAIKELQAKGFKLPDYPQDPKSYQEIDIRN 126 Query: 127 RYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHGGDFYAG 186 RY K GSAVNPVLREGNSDRRAP AVK YAR +PHSM +WSMASRTHVA M GDFY G Sbjct: 127 RYGKCLGSAVNPVLREGNSDRRAPKAVKEYARNNPHSMGEWSMASRTHVATMRHGDFYHG 186 Query: 187 EKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEEQMQDAF 246 EKS+TLD+A DVKM+L TK G+ +VLKPK+SL+ G+IIDSMFMSKKALC +YEEQM+DA Sbjct: 187 EKSMTLDRARDVKMELATKKGKIVVLKPKVSLRDGDIIDSMFMSKKALCEFYEEQMEDAR 246 Query: 247 ETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMSGVYEKI 306 +T ++ S+HVKATMMKVSHPIVFGHAV+T+YK+ F KH LF E+GVN NNG+ +Y KI Sbjct: 247 KTGVMFSLHVKATMMKVSHPIVFGHAVKTFYKEAFAKHQDLFDELGVNVNNGLVDLYSKI 306 Query: 307 NTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIRAGGKMW 366 TL +++ E++ DL A RP LAMVDSA+GI+N ++P+DVIVDASMPAMIRAGGKM+ Sbjct: 307 ETLTASQRDEIIQDLHACHEHRPELAMVDSARGISNFYSPSDVIVDASMPAMIRAGGKMY 366 Query: 367 NAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAEEYGSHD 426 A G+ +DTKA+ PESTF+RIYQE+INFCKTNGAFDP TMGTVPNVGLMAQ+AEEYGSHD Sbjct: 367 GADGRAKDTKAVNPESTFSRIYQEIINFCKTNGAFDPATMGTVPNVGLMAQQAEEYGSHD 426 Query: 427 KTFEIAQAGVARIVTL-DGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRARLSGMP 485 KTFEI + GVA IV L G+VLL QNVE GDIWR+C V DAA+RDWVKLAV+R R SGMP Sbjct: 427 KTFEIPEDGVANIVDLTTGEVLLTQNVETGDIWRLCVVTDAAIRDWVKLAVSRMRNSGMP 486 Query: 486 AVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDTISVTG 545 +FWLDPYRPHE ELIKKV YLKDHD +G DIQIMSQVR+MRYT ER+IRGLDTI+ TG Sbjct: 487 VLFWLDPYRPHENELIKKVRAYLKDHDTSGLDIQIMSQVRSMRYTCERLIRGLDTIAATG 546 Query: 546 NILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENHLRWDS 605 NILRDYLTDLFPI+ELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHV+QLV ENHLRWDS Sbjct: 547 NILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRWDS 606 Query: 606 LGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNRGSHFYL 665 LGEFLALAVS+E++GIKTGN RAKILAKTLD ATGKLLDN KSPS K GELDNRGS FYL Sbjct: 607 LGEFLALAVSLEDLGIKTGNERAKILAKTLDVATGKLLDNRKSPSRKAGELDNRGSQFYL 666 Query: 666 ALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLPDREKT 725 A+YWAQELA Q DD L F PLA+ LA+NE IV ELN QGK VDIGGYY PD E Sbjct: 667 AMYWAQELATQTDDQHLRNYFTPLAETLAKNECTIVAELNEAQGKAVDIGGYYAPDAELA 726 Query: 726 FAVMRPSTTLN 736 AVMRPS N Sbjct: 727 KAVMRPSAVFN 737 >PA2624 [C] COG2838 Monomeric isocitrate dehydrogenase Pae Pseudomonas aeruginosa Length = 741 Score = 1066 bits (2757), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/735 (69%), Positives = 596/735 (81%), Gaps = 1/735 (0%) Query: 8 IIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTDEQKVPDN 67 I YT TDEAP LAT+SLLPIVK F A+AGIDV SDIS+A RILA F + L +Q++ D+ Sbjct: 7 ITYTFTDEAPALATYSLLPIVKAFAASAGIDVETSDISLAGRILANFADRLEADQRIEDD 66 Query: 68 LAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEEEKALQKR 127 LA L L SPDANIIKLPNISAS+ QL+ AI ELQ GYK+PD+PE+P T+EEK ++ R Sbjct: 67 LARLAVLATSPDANIIKLPNISASVPQLKGAIAELQGLGYKVPDFPEDPQTDEEKEVRAR 126 Query: 128 YAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHGGDFYAGE 187 YAK+ GSAVNPVLREGNSDRRAP AVK YARKHPHSM KWSMASR+H +M GGDF++ E Sbjct: 127 YAKILGSAVNPVLREGNSDRRAPAAVKAYARKHPHSMGKWSMASRSHADYMRGGDFFSSE 186 Query: 188 KSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEEQMQDAFE 247 +S+T+ KA DV+++ V K G+ + +K ++SLQ GE++DSMFMS L ++E+ +QD E Sbjct: 187 QSITMAKAGDVRIEFVGKDGK-VEVKKQLSLQEGEVLDSMFMSCGKLRDFFEKTLQDCKE 245 Query: 248 TDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMSGVYEKIN 307 T ++ S+HVKATMMK+SHPIVFGHAV YYKD F K +LF E+GVNPNNG+S VY+KI Sbjct: 246 TGVMWSLHVKATMMKISHPIVFGHAVSVYYKDVFDKWGQLFEELGVNPNNGISSVYDKIK 305 Query: 308 TLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIRAGGKMWN 367 +LP +++ E+L D+ + RP +AMVDS KGITNLH P+DVIVDASMPAMIR G+MW Sbjct: 306 SLPASQQEEILHDIHEVYSHRPEMAMVDSVKGITNLHIPSDVIVDASMPAMIRNSGQMWG 365 Query: 368 AAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAEEYGSHDK 427 GK +DTKA++PEST+ARIYQEMINFCKTNGAFDPTTMG+VPNVGLMAQKAEEYGSHDK Sbjct: 366 KDGKQKDTKAVMPESTYARIYQEMINFCKTNGAFDPTTMGSVPNVGLMAQKAEEYGSHDK 425 Query: 428 TFEIAQAGVARIVTLDGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRARLSGMPAV 487 TFE+ G R+V DG VL++ VE GDIWR CQ KDA +RDWVKLAVTRAR S PA+ Sbjct: 426 TFEMTADGTMRVVLADGSVLMQHKVETGDIWRACQTKDAPIRDWVKLAVTRARQSDTPAI 485 Query: 488 FWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDTISVTGNI 547 FWLDP R H+ EL KKV YLKDHDLTG DI IM A+R ++ER+IRG DTISVTGN+ Sbjct: 486 FWLDPERAHDRELRKKVELYLKDHDLTGLDISIMGYNEAIRVSMERLIRGKDTISVTGNV 545 Query: 548 LRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENHLRWDSLG 607 LRDYLTDLFPIMELGTSAKMLSIVPLMAGGGM+ETGAGGSAPKHVQQLV EN+LRWDSLG Sbjct: 546 LRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEENYLRWDSLG 605 Query: 608 EFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNRGSHFYLAL 667 EFLALAVS+EE GIKTGNA+AK+L K LD ATGKLLDNNKSPS K G++DNRGSHFYLA+ Sbjct: 606 EFLALAVSLEETGIKTGNAKAKLLGKALDEATGKLLDNNKSPSRKVGDIDNRGSHFYLAM 665 Query: 668 YWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLPDREKTFA 727 YWAQ LAAQ +DAEL FAPLAKAL E E IV ELN+VQGK +IGGYY + E T Sbjct: 666 YWAQALAAQNEDAELKAHFAPLAKALTEQEATIVAELNAVQGKPAEIGGYYRSNPELTSK 725 Query: 728 VMRPSTTLNQALETL 742 VMRPS T N A+++L Sbjct: 726 VMRPSATFNAAIDSL 740 >VC1141 [C] COG2838 Monomeric isocitrate dehydrogenase Vch Vibrio cholerae Length = 741 Score = 970 bits (2508), Expect = 0.0, Method: Compositional matrix adjust. Identities = 468/738 (63%), Positives = 583/738 (78%) Query: 3 TGNPTIIYTLTDEAPYLATHSLLPIVKKFTAAAGIDVVESDISVAARILAEFPEYLTDEQ 62 T PTIIYT+TDEAP LAT+SLLPI++ FTA++GI+V DIS+A RILA FPE+LT+EQ Sbjct: 3 TNKPTIIYTITDEAPALATYSLLPIIQSFTASSGINVETRDISLAGRILANFPEHLTEEQ 62 Query: 63 KVPDNLAALGALTQSPDANIIKLPNISASILQLQAAIRELQSRGYKLPDYPENPTTEEEK 122 ++ D L LG L ++P+ANIIKLPNISAS+ QL+AAI+ELQ +GY LP+YPE P++ EE+ Sbjct: 63 RISDALTELGELAKTPEANIIKLPNISASVPQLKAAIKELQDKGYALPNYPEEPSSYEEE 122 Query: 123 ALQKRYAKVTGSAVNPVLREGNSDRRAPNAVKNYARKHPHSMAKWSMASRTHVAHMHGGD 182 A++ Y K+ GSAVNPVLREGNSDRRAP +VKNYA+K+PHSM WS S++HVA M D Sbjct: 123 AIKATYDKIKGSAVNPVLREGNSDRRAPASVKNYAKKNPHSMGAWSKDSKSHVASMSDKD 182 Query: 183 FYAGEKSLTLDKAVDVKMDLVTKSGETIVLKPKISLQAGEIIDSMFMSKKALCAYYEEQM 242 F+ EKS+T+ A V ++ V K G VLK +LQ EIID+ MSKKAL A++E+++ Sbjct: 183 FFGSEKSMTVSGATKVAIEFVGKEGAVKVLKKPFALQDKEIIDTSVMSKKALIAFFEKEI 242 Query: 243 QDAFETDLLLSVHVKATMMKVSHPIVFGHAVRTYYKDTFTKHAKLFAEIGVNPNNGMSGV 302 DA D+L S+H+KATMMKVS P++FGHAV+ YYK F K+ +LF ++GV+ NNG+ V Sbjct: 243 ADAKAQDVLFSLHMKATMMKVSDPVIFGHAVKVYYKAVFDKYGQLFDQLGVDVNNGLGDV 302 Query: 303 YEKINTLPDAKKAEVLADLKADEAKRPRLAMVDSAKGITNLHAPNDVIVDASMPAMIRAG 362 Y KI +LP+A++AE+ A ++A A +P LAMVDS +GITNLH P+DVIVDASMPAMIR Sbjct: 303 YAKIQSLPEAQRAEIEAAIQAVYATQPALAMVDSDRGITNLHVPSDVIVDASMPAMIRTS 362 Query: 363 GKMWNAAGKTEDTKALLPESTFARIYQEMINFCKTNGAFDPTTMGTVPNVGLMAQKAEEY 422 G+MW GK +DTKA +P+ +A +YQ +I+FCK +GAFDPTTMG+VPNVGLMAQKAEEY Sbjct: 363 GQMWGPDGKQKDTKATIPDRCYAGVYQTVIDFCKQHGAFDPTTMGSVPNVGLMAQKAEEY 422 Query: 423 GSHDKTFEIAQAGVARIVTLDGQVLLEQNVEEGDIWRMCQVKDAAVRDWVKLAVTRARLS 482 GSHDKTF + GV R++ G+VLLEQ+VE GDI+RMCQVKDA ++DWVKLAVTRAR S Sbjct: 423 GSHDKTFILDAEGVVRVIDEAGKVLLEQSVEAGDIFRMCQVKDAPIQDWVKLAVTRARAS 482 Query: 483 GMPAVFWLDPYRPHEAELIKKVNTYLKDHDLTGADIQIMSQVRAMRYTLERVIRGLDTIS 542 PAVFWLDP R H+AELIKKVN YL +HD +G +I+I+S + A +Y+L R+ G DTIS Sbjct: 483 NTPAVFWLDPARAHDAELIKKVNQYLPNHDTSGLEIKILSPIEATQYSLVRMKAGQDTIS 542 Query: 543 VTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMFETGAGGSAPKHVQQLVGENHLR 602 VTGN+LRDYLTDLFPI+ELGTSAKMLSIVPLM GGG+FETGAGGSAPKHVQQ+ ENHLR Sbjct: 543 VTGNVLRDYLTDLFPILELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQVQKENHLR 602 Query: 603 WDSLGEFLALAVSIEEVGIKTGNARAKILAKTLDAATGKLLDNNKSPSPKTGELDNRGSH 662 WDSLGEFLALA S+E + + TGN +A++LA LD ATGK LD NKSPS + GE+DNRGSH Sbjct: 603 WDSLGEFLALAASLEHLSVVTGNRKAQVLADALDKATGKFLDMNKSPSRRVGEIDNRGSH 662 Query: 663 FYLALYWAQELAAQKDDAELAKQFAPLAKALAENEQKIVEELNSVQGKQVDIGGYYLPDR 722 FYLA YWAQ LA Q DA+LA +FAP+AKAL E E +IV ELN QGK D+GGYY P+ Sbjct: 663 FYLATYWAQALAEQTADADLAAEFAPIAKALEEKEAQIVAELNGAQGKPGDLGGYYAPEF 722 Query: 723 EKTFAVMRPSTTLNQALE 740 K +MRPS+T N ++ Sbjct: 723 AKVAPLMRPSSTFNAIID 740