BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0179.p (428 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 621 e-177 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 596 e-170 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 573 e-163 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 557 e-158 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 277 4e-74 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 621 bits (1601), Expect = e-177, Method: Compositional matrix adjust. Identities = 301/427 (70%), Positives = 355/427 (83%), Gaps = 1/427 (0%) Query: 1 MTTSTASQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNEFASLMLTFMTFG 60 M T ++SK ++ RV SGNF+EM+DF ++G+YA I+ FFP+DNEF SLML+ +TFG Sbjct: 1 MHTHNPNESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFG 60 Query: 61 AGFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYATIGALAPLLVLIG 120 GFLMRPLGA+ILGAY+DR GRR GLI+TL LMA GT+LIA VP YATIG APLLVLIG Sbjct: 61 VGFLMRPLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIG 120 Query: 121 RLLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYLLSTSLTPA 180 RLLQGFSAGVELGGVSVYLAE++TPG KGF+VSWQSASQQVA++ AA +G LLS L+P Sbjct: 121 RLLQGFSAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPK 180 Query: 181 EVSGWGWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKLVIAG 240 E+ WGWR+PF +GCLIVP LF+IRRSLQETEEF +RKHRP+ G+IFRSM ENW+LV AG Sbjct: 181 EMGEWGWRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGAG 240 Query: 241 MMLVSMTTVSFYLITVYTPTFGKNVLKLSTEASLIVTLCVGLSNFIWLPIMGALSDRVGR 300 +LV MTTVSFYLIT YTPTFGK+VL LS SLIVTLCVG SNF WLP+MG++SDR+GR Sbjct: 241 TLLVVMTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGR 300 Query: 301 RPLLVTFTVLTILTAYPAVNWLVHDASFAKMLIVELWLSFLYASYNGAMVVALTEVMPAD 360 RPLL+TFT LT+LTAYPA+ WL+ + SF ++L VELWLSFLY SYNGAMVV LTE+MP Sbjct: 301 RPLLITFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPA 360 Query: 361 VRTAGFSLAYSLATAVFGGFTPAIATGLIEYTHDKAAPGIWMSTAAVCGLIATLILYRNK 420 VRT GFSLAYSLATA+FGGFTPAIAT LI T +KA PG+W+S AA+CGL+ATLI+ + Sbjct: 361 VRTTGFSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVK-P 419 Query: 421 AARQAAT 427 A R T Sbjct: 420 AGRHVHT 426 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 596 bits (1537), Expect = e-170, Method: Compositional matrix adjust. Identities = 290/426 (68%), Positives = 343/426 (80%), Gaps = 1/426 (0%) Query: 1 MTTSTASQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNEFASLMLTFMTFG 60 M T ++SK + RV SGNF+EMFDF ++G+YAT I+ FFP+ N F SLML+ MTFG Sbjct: 1 MHTHNPNESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFG 60 Query: 61 AGFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYATIGALAPLLVLIG 120 AGFLMRPLGAI+LGAY+DR GRR GLI+TL LMA GTMLIA VP Y TIG APLLVLIG Sbjct: 61 AGFLMRPLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIG 120 Query: 121 RLLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYLLSTSLTPA 180 RLLQGFSAG E GGVSVYL+E+ATPG KGFYVSWQS SQQVA++ AA +G LLS L+P Sbjct: 121 RLLQGFSAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPK 180 Query: 181 EVSGWGWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKLVIAG 240 E+ WGWR+PF IGCLIVP LF IRRSL+ETEEF +RKHRP+ G++ RSM ENW+L AG Sbjct: 181 EMGEWGWRVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWRLAGAG 240 Query: 241 MMLVSMTTVSFYLITVYTPTFGKNVLKLSTEASLIVTLCVGLSNFIWLPIMGALSDRVGR 300 +L MTTVSFYLIT YTPTFG+NVL +S SLIVTLCVG SN IWLP+MG+LSDR+GR Sbjct: 241 TLLAVMTTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGR 300 Query: 301 RPLLVTFTVLTILTAYPAVNWLVHDASFAKMLIVELWLSFLYASYNGAMVVALTEVMPAD 360 R L+ F+ LT+LTAYPA+ WL+ + SF ++L VELWLSFLY YNGAM+V LTE+MP Sbjct: 301 RTPLIVFSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQ 360 Query: 361 VRTAGFSLAYSLATAVFGGFTPAIATGLIEYTHDKAAPGIWMSTAAVCGLIATLILYRNK 420 +RT GFSLAYSLATA+FGGFTPAIATGLI T +KA PG+W+S AA+CGL+ATL + + + Sbjct: 361 LRTTGFSLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKPQ 420 Query: 421 AARQAA 426 R AA Sbjct: 421 -PRPAA 425 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 573 bits (1478), Expect = e-163, Method: Compositional matrix adjust. Identities = 270/416 (64%), Positives = 340/416 (81%) Query: 2 TTSTASQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNEFASLMLTFMTFGA 61 T +T+ F +LRVTSGNF+E FDFFLFGFYAT+I++ FFP+++EFASLMLTF FG+ Sbjct: 5 TPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGS 64 Query: 62 GFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYATIGALAPLLVLIGR 121 GFLMRP+GAI+LGAY+DR+GRR+GL+VTLA+M GT+LIA VP Y TIG AP LVL+GR Sbjct: 65 GFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGR 124 Query: 122 LLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYLLSTSLTPAE 181 LLQGFSAGVELGGVSVYL+E+ATPGNKGFY SWQSASQQVAI+VAA IGY L+ +L Sbjct: 125 LLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDA 184 Query: 182 VSGWGWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKLVIAGM 241 +S WGWRIPFFIGC+I+P++FV+RRSLQETE F++RKHRP T +IF ++ +NW+++ AG Sbjct: 185 ISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAGT 244 Query: 242 MLVSMTTVSFYLITVYTPTFGKNVLKLSTEASLIVTLCVGLSNFIWLPIMGALSDRVGRR 301 +LV+MTT +FY ITVYTPT+G+ VL LS SLIVT+ VG+SNFIWLPI GA+SDR+GRR Sbjct: 245 LLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRR 304 Query: 302 PLLVTFTVLTILTAYPAVNWLVHDASFAKMLIVELWLSFLYASYNGAMVVALTEVMPADV 361 +L+ T+L ++T +P + WL F +M +V LW SF + YNGAMV ALTEVMP V Sbjct: 305 AVLMGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYV 364 Query: 362 RTAGFSLAYSLATAVFGGFTPAIATGLIEYTHDKAAPGIWMSTAAVCGLIATLILY 417 RT GFSLA+SLATA+FGG TPAI+T L++ T DK++PG W+ AA+CGL AT +L+ Sbjct: 365 RTVGFSLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLF 420 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 557 bits (1436), Expect = e-158, Method: Compositional matrix adjust. Identities = 290/420 (69%), Positives = 349/420 (83%) Query: 6 ASQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNEFASLMLTFMTFGAGFLM 65 +++SK + RV SGNF+EM+DF ++GFYAT I+K FFP DN FASLML+ TFGAGFLM Sbjct: 3 SNKSKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLM 62 Query: 66 RPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYATIGALAPLLVLIGRLLQG 125 RPLGA+ LGAY+DR GRRQGLI+TL LMA+GT+LIAFVP YAT+G APLLVL GRLLQG Sbjct: 63 RPLGAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQG 122 Query: 126 FSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYLLSTSLTPAEVSGW 185 FSAGVELGGVSVYL+E+ATPG KGF+VSWQSASQQVA++ A +G LL+ L+P ++ W Sbjct: 123 FSAGVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEW 182 Query: 186 GWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKLVIAGMMLVS 245 GWR+PFFIGCLIVP LFVIRRSL+ET EF R HRPS Q+ RS+ +N+ +V+AG +V Sbjct: 183 GWRVPFFIGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVV 242 Query: 246 MTTVSFYLITVYTPTFGKNVLKLSTEASLIVTLCVGLSNFIWLPIMGALSDRVGRRPLLV 305 MTTVSFYLIT YTPTFGKN L+LS SL+VT+C+GLSNFIWLP+MGA SDR+GR+PLL+ Sbjct: 243 MTTVSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLL 302 Query: 306 TFTVLTILTAYPAVNWLVHDASFAKMLIVELWLSFLYASYNGAMVVALTEVMPADVRTAG 365 + L +LTAYPA++WLV + SFA +L VELWLSFLY+SYNGAMVVALTEVMPADVRT G Sbjct: 303 GASALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTG 362 Query: 366 FSLAYSLATAVFGGFTPAIATGLIEYTHDKAAPGIWMSTAAVCGLIATLILYRNKAARQA 425 FSLAYSLATA FGGFTPA+ T LI ++AAPGIW+S AA+ GL+ATL+L+R + A Sbjct: 363 FSLAYSLATATFGGFTPAVCTWLIHTLDNRAAPGIWLSGAALLGLLATLVLFRRRGKEIA 422 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 277 bits (708), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 163/429 (37%), Positives = 237/429 (55%), Gaps = 9/429 (2%) Query: 1 MTTSTASQSKFSTVLRVTSGNFMEMFDFFLFGFYATHISKAFFPSDNEFASLMLTFMTFG 60 M + S+ V GN +E +DF ++GF ++ I++ FFPS +E+ SL++ TFG Sbjct: 1 MHACPSGTSRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFG 60 Query: 61 AGFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTMLIAFVPSYATIGALAPLLVLIG 120 GF MRP+G ++LG Y DR GR+ + + + LM L +IAF P+YA IG APLL++I Sbjct: 61 VGFFMRPVGGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIA 120 Query: 121 RLLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQVAIIVAAAIGYLLSTSLTPA 180 R+LQGF+ G E + +L E A P +G Y SWQ Q +A+ A +G L++ L Sbjct: 121 RMLQGFATGGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAE 180 Query: 181 EVSGWGWRIPFFIGCLIVPVLFVIRRSLQETEEFMRRKHRPSTGQIFRSMIENWKL-VIA 239 + WGWR+PF G LI PV IRR + ETE F+ P Q ++ ++ V+ Sbjct: 181 ALESWGWRVPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLV 240 Query: 240 GMMLVSMTTVSFYLITVYTPTFGKNVLKLSTEASLIVTL-CVGLSNFIWLPIMGALSDRV 298 M L + TVSFY++ V PTF L L + +V + V L + +P+ G LSDRV Sbjct: 241 SMGLTVVGTVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLV-IPLAGGLSDRV 299 Query: 299 GRRPLLVTFTVLTILTAYPAVNWLVHDASFAKMLIVELWLSFLYASYNGAMVVALTEVMP 358 GRRP+L+ T+ +L YP W+ S ++L+++L L + G A+ E P Sbjct: 300 GRRPVLLVATLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFP 359 Query: 359 ADVRTAGFSLAYSLATAVFGGFTPAIATGLIEYTHDKAAPGIWMSTAAVCGLIATLILYR 418 VR+ G ++AY+LA +FGGF P I T L E AP ++ AA GL+ATL L Sbjct: 360 VRVRSTGLAVAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYL-- 417 Query: 419 NKAARQAAT 427 R+ AT Sbjct: 418 ----REGAT 422